메뉴 건너뛰기




Volumn 16, Issue 7, 2017, Pages 789-799

Desmoteplase for acute ischemic stroke: A systematic review and meta analysis of randomized controlled trials

Author keywords

Desmoteplase; Ischemic stroke; Meta analysis; Mortality; Reperfusion; Tissue plasminogen activator

Indexed keywords

DESMOTEPLASE; TISSUE PLASMINOGEN ACTIVATOR; PLASMINOGEN ACTIVATOR; SALIVARY PLASMINOGEN ACTIVATOR ALPHA 1, DESMODUS ROTUNDUS;

EID: 85038443378     PISSN: 18715273     EISSN: 19963181     Source Type: Journal    
DOI: 10.2174/1871527315666161213110104     Document Type: Article
Times cited : (16)

References (22)
  • 1
    • 84969376984 scopus 로고    scopus 로고
    • Executive Summary: Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association
    • Mozaffarian D, Benjamin EJ, Go AS, et al. Executive Summary: Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association. Circulation 2016; 133: 447.
    • (2016) Circulation , vol.133 , pp. 447
    • Mozaffarian, D.1    Benjamin, E.J.2    Go, A.S.3
  • 2
    • 84949086655 scopus 로고    scopus 로고
    • Global, regional, and national disability-adjusted life years (Dalys) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: Quantifying the epidemiological transition
    • Murray CJL, Barber RM, Foreman KJ, et al Global, regional, and national disability-adjusted life years (dalys) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition. Lancet 2015; 386: 2145-91.
    • (2015) Lancet , vol.386 , pp. 2145-2191
    • Murray, C.1    Barber, R.M.2    Foreman, K.J.3
  • 3
    • 84992904621 scopus 로고    scopus 로고
    • Intravenous thrombolysis for acute ischemic stroke within 3 hours versus between 3 and 4.5 hours of symptom onset
    • Cheng NT, Kim AS. Intravenous thrombolysis for acute ischemic stroke within 3 hours versus between 3 and 4.5 hours of symptom onset. Neurohospitalist 2015; 5: 101-09.
    • (2015) Neurohospitalist , vol.5 , pp. 101-109
    • Cheng, N.T.1    Kim, A.S.2
  • 4
    • 84992884507 scopus 로고    scopus 로고
    • Absolute and relative contraindications to IV rt-PA for acute ischemic stroke
    • Fugate JE, Rabinstein AA. Absolute and relative contraindications to IV rt-PA for acute ischemic stroke. Neurohospitalist 2015; 5: 110-21.
    • (2015) Neurohospitalist , vol.5 , pp. 110-121
    • Fugate, J.E.1    Rabinstein, A.A.2
  • 5
    • 84891765341 scopus 로고    scopus 로고
    • Tissue plasminogen activator overdose in acute ischemic stroke patients linked to poorer functional outcomes
    • Sahlas DJ, Gould L, Swartz RH, et al. Tissue plasminogen activator overdose in acute ischemic stroke patients linked to poorer functional outcomes. J Stroke Cerebrovasc Dis 2014; 23: 155-59.
    • (2014) J Stroke Cerebrovasc Dis , vol.23 , pp. 155-159
    • Sahlas, D.J.1    Gould, L.2    Swartz, R.H.3
  • 6
    • 4544316926 scopus 로고    scopus 로고
    • The neurotoxicity of tissue plasminogen activator&quest
    • Kaur J, Zhao Z, Klein GM, et al. The neurotoxicity of tissue plasminogen activator& quest. J Cerebral Blood Flow Metabol 2004; 24: 945-963.
    • (2004) J Cerebral Blood Flow Metabol , vol.24 , pp. 945-963
    • Kaur, J.1    Zhao, Z.2    Klein, G.M.3
  • 7
    • 0025937492 scopus 로고
    • Effective thrombolysis without marked plasminemia after bolus intravenous administration of vampire bat salivary plasminogen activator in rabbits
    • Gardell SJ, Ramjit DR, Stabilito II, et al. Effective thrombolysis without marked plasminemia after bolus intravenous administration of vampire bat salivary plasminogen activator in rabbits. Circulation 1991; 84: 244-253.
    • (1991) Circulation , vol.84 , pp. 244-253
    • Gardell, S.J.1    Ramjit, D.R.2    Stabilito, I.I.3
  • 8
    • 80053651851 scopus 로고    scopus 로고
    • Desmoteplase: Discovery, insights and opportunities for ischaemic stroke
    • Medcalf RL, Desmoteplase: discovery, insights and opportunities for ischaemic stroke. Br J Pharmacol 2012; 165:75-89.
    • (2012) Br J Pharmacol , vol.165 , pp. 75-89
    • Medcalf, R.L.1
  • 9
    • 0028961324 scopus 로고
    • Vampire bat salivary plasminogen activator evokes minimal bleeding relative to tissuetype plasminogen activator as assessed by a rabbit cuticle bleeding time model
    • Mellott MJ, Ramjit DR, Stabilito II, et al. Vampire bat salivary plasminogen activator evokes minimal bleeding relative to tissuetype plasminogen activator as assessed by a rabbit cuticle bleeding time model. Thromb Haemost 1995; 73: 478-483.
    • (1995) Thromb Haemost , vol.73 , pp. 478-483
    • Mellott, M.J.1    Ramjit, D.R.2    Stabilito, I.I.3
  • 10
    • 19944426190 scopus 로고    scopus 로고
    • The Desmoteplase in Acute Ischemic Stroke Trial (DIAS) a phase II MRI-based 9-hour window acute stroke thrombolysis trial with intravenous desmoteplase
    • Hacke W, Albers G, Al-Rawi Y, et al. The Desmoteplase in Acute Ischemic Stroke Trial (DIAS) a phase II MRI-based 9-hour window acute stroke thrombolysis trial with intravenous desmoteplase. Stroke 2005; 36: 66-73.
    • (2005) Stroke , vol.36 , pp. 66-73
    • Hacke, W.1    Albers, G.2    Al-Rawi, Y.3
  • 11
    • 33646705400 scopus 로고    scopus 로고
    • Dose escalation of desmoteplase for acute ischemic stroke (DEDAS) evidence of safety and efficacy 3 to 9 hours after stroke onset
    • Furlan AJ, Eyding D, Albers GW, et al. Dose escalation of desmoteplase for acute ischemic stroke (DEDAS) evidence of safety and efficacy 3 to 9 hours after stroke onset. Stroke 2006; 37: 1227-31.
    • (2006) Stroke , vol.37 , pp. 1227-1231
    • Furlan, A.J.1    Eyding, D.2    Albers, G.W.3
  • 12
    • 58249134578 scopus 로고    scopus 로고
    • Intravenous desmoteplase in patients with acute ischaemic stroke selected by MRI perfusiondiffusion weighted imaging or perfusion CT (DIAS-2): A prospective, randomised, double-blind, placebo-controlled study
    • Hacke W, Furlan AJ, Al-Rawi Y, et al. Intravenous desmoteplase in patients with acute ischaemic stroke selected by MRI perfusiondiffusion weighted imaging or perfusion CT (DIAS-2): a prospective, randomised, double-blind, placebo-controlled study. Lancet Neurol 2009; 8: 141-150.
    • (2009) Lancet Neurol , vol.8 , pp. 141-150
    • Hacke, W.1    Furlan, A.J.2    Al-Rawi, Y.3
  • 13
    • 84929519483 scopus 로고    scopus 로고
    • Safety and efficacy of desmoteplase given 3-9 h after ischaemic stroke in patients with occlusion or high-grade stenosis in major cerebral arteries (DIAS-3): A double-blind, randomised, placebo-controlled phase 3 trial
    • Albers GW, von Kummer R, Truelsen T, et al. Safety and efficacy of desmoteplase given 3-9 h after ischaemic stroke in patients with occlusion or high-grade stenosis in major cerebral arteries (DIAS-3): a double-blind, randomised, placebo-controlled phase 3 trial. Lancet Neurol 2015; 14: 575-584.
    • (2015) Lancet Neurol , vol.14 , pp. 575-584
    • Albers, G.W.1    Von Kummer, R.2    Truelsen, T.3
  • 15
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M, Smith GD, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. Bmj 1997; 315: 629-634.
    • (1997) Bmj , vol.315 , pp. 629-634
    • Egger, M.1    Smith, G.D.2    Schneider, M.3    Minder, C.4
  • 16
    • 84940397254 scopus 로고    scopus 로고
    • Safety and tolerability of desmoteplase within 3 to 9 hours after symptoms onset in japanese patients with ischemic stroke
    • Mori E, Minematsu K, Nakagawara J, et al. Safety and tolerability of desmoteplase within 3 to 9 hours after symptoms onset in japanese patients with ischemic stroke. Stroke 2015; 46: 2549-54.
    • (2015) Stroke , vol.46 , pp. 2549-2554
    • Mori, E.1    Minematsu, K.2    Nakagawara, J.3
  • 18
    • 40949161352 scopus 로고    scopus 로고
    • Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): A placebo-controlled randomised trial
    • Davis SM, Donnan GA, Parsons MW, et al. Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial. Lancet Neurol 2008; 7: 299-09.
    • (2008) Lancet Neurol , vol.7 , pp. 299-309
    • Davis, S.M.1    Donnan, G.A.2    Parsons, M.W.3
  • 19
    • 33845298309 scopus 로고    scopus 로고
    • Magnetic resonance imaging profiles predict clinical response to early reperfusion: The diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study
    • Albers GW, Thijs VN, Wechsler L, et al. Magnetic resonance imaging profiles predict clinical response to early reperfusion: The diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study. Annal Neurol 2006; 60: 508-17.
    • (2006) Annal Neurol , vol.60 , pp. 508-517
    • Albers, G.W.1    Thijs, V.N.2    Wechsler, L.3
  • 21
    • 60049091968 scopus 로고    scopus 로고
    • Penumbral selection of patients for trials of acute stroke therapy
    • Donnan GA, Baron J-C, Ma H, Davis SM. Penumbral selection of patients for trials of acute stroke therapy. Lancet Neurol 2009; 8: 261-69.
    • (2009) Lancet Neurol , vol.8 , pp. 261-269
    • Donnan, G.A.1    Baron, J.-C.2    Ma, H.3    Davis, S.M.4
  • 22
    • 74049115448 scopus 로고    scopus 로고
    • Mismatch-based delayed thrombolysis a meta-analysis
    • Mishra NK, Albers GW, Davis SM, et al. Mismatch-based delayed thrombolysis a meta-analysis. Stroke 2010; 41: e25-33.
    • (2010) Stroke , vol.41 , pp. e25-e33
    • Mishra, N.K.1    Albers, G.W.2    Davis, S.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.