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Volumn 113, Issue 1, 2018, Pages

The RISK pathway and beyond

Author keywords

Cardioprotection; Ischemia reperfusion injury; Ischemic preconditioning; RISK pathway

Indexed keywords

ACUTE HEART INFARCTION; APOPTOSIS; HEART INFARCTION PREVENTION; HEART PROTECTION; HUMAN; NONHUMAN; REPERFUSION INJURY SALVAGE KINASE SIGNALING; REVIEW; SIGNAL TRANSDUCTION; SURVIVAL; ANIMAL; CARDIAC MUSCLE; ENZYMOLOGY; HEART INFARCTION; METABOLISM; MYOCARDIAL ISCHEMIA REPERFUSION INJURY; NECROSIS; PATHOLOGY;

EID: 85035108746     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-017-0662-x     Document Type: Review
Times cited : (158)

References (45)
  • 2
    • 0035197082 scopus 로고    scopus 로고
    • Cardioprotective effects of transforming growth factor-beta1 during early reoxygenation or reperfusion are mediated by p42/p44 MAPK
    • COI: 1:CAS:528:DC%2BD3MXovVOnsbk%3D, PID: 11707697
    • Baxter GF, Mocanu MM, Brar BK, Latchman DS, Yellon DM (2001) Cardioprotective effects of transforming growth factor-beta1 during early reoxygenation or reperfusion are mediated by p42/p44 MAPK. J Cardiovasc Pharmacol 38:930–939
    • (2001) J Cardiovasc Pharmacol , vol.38 , pp. 930-939
    • Baxter, G.F.1    Mocanu, M.M.2    Brar, B.K.3    Latchman, D.S.4    Yellon, D.M.5
  • 3
    • 84873350013 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibition protects CyPD knockout mice independently of RISK/mPTP signalling: a parallel pathway to protection
    • PID: 23361433
    • Bell RM, Kunuthur SP, Hendry C, Bruce-Hickman D, Davidson S, Yellon DM (2013) Matrix metalloproteinase inhibition protects CyPD knockout mice independently of RISK/mPTP signalling: a parallel pathway to protection. Basic Res Cardiol 108:331. https://doi.org/10.1007/s00395-013-0331-7
    • (2013) Basic Res Cardiol , vol.108 , pp. 331
    • Bell, R.M.1    Kunuthur, S.P.2    Hendry, C.3    Bruce-Hickman, D.4    Davidson, S.5    Yellon, D.M.6
  • 4
    • 36049029970 scopus 로고    scopus 로고
    • Cardioprotection: spotlight on PKG
    • COI: 1:CAS:528:DC%2BD2sXht1ynt7rL, PID: 17876305
    • Cohen MV, Downey JM (2007) Cardioprotection: spotlight on PKG. Br J Pharmacol 152:833–834. https://doi.org/10.1038/sj.bjp.0707453
    • (2007) Br J Pharmacol , vol.152 , pp. 833-834
    • Cohen, M.V.1    Downey, J.M.2
  • 5
    • 29244467695 scopus 로고    scopus 로고
    • Signalling via the reperfusion injury signalling kinase (RISK) pathway links closure of the mitochondrial permeability transition pore to cardioprotection
    • COI: 1:CAS:528:DC%2BD2MXhtlCrtr3K, PID: 16280253
    • Davidson SM, Hausenloy D, Duchen MR, Yellon DM (2006) Signalling via the reperfusion injury signalling kinase (RISK) pathway links closure of the mitochondrial permeability transition pore to cardioprotection. Int J Biochem Cell Biol 38:414–419. https://doi.org/10.1016/j.biocel.2005.09.017
    • (2006) Int J Biochem Cell Biol , vol.38 , pp. 414-419
    • Davidson, S.M.1    Hausenloy, D.2    Duchen, M.R.3    Yellon, D.M.4
  • 6
    • 85025173340 scopus 로고    scopus 로고
    • STAT5 fits the RISK profile for cardioprotection
    • PID: 24058753
    • Davidson SM, Yellon DM (2012) STAT5 fits the RISK profile for cardioprotection. JAK-STAT 1:73–76. https://doi.org/10.4161/jkst.20072
    • (2012) JAK-STAT , vol.1 , pp. 73-76
    • Davidson, S.M.1    Yellon, D.M.2
  • 7
    • 84908219745 scopus 로고    scopus 로고
    • Top 10 cardiovascular therapies and interventions for the next decade
    • PID: 25267423
    • Fuster V (2014) Top 10 cardiovascular therapies and interventions for the next decade. Nat Rev Cardiol 11:671–683. https://doi.org/10.1038/nrcardio.2014.137
    • (2014) Nat Rev Cardiol , vol.11 , pp. 671-683
    • Fuster, V.1
  • 8
    • 85014430719 scopus 로고    scopus 로고
    • Ischemic preconditioning in pigs: a causal role for signal transducer and activator of transcription 3
    • PID: 28039203
    • Gent S, Skyschally A, Kleinbongard P, Heusch G (2017) Ischemic preconditioning in pigs: a causal role for signal transducer and activator of transcription 3. Am J Physiol Heart Circ Physiol 312:H478–H484. https://doi.org/10.1152/ajpheart.00749.2016
    • (2017) Am J Physiol Heart Circ Physiol , vol.312 , pp. H478-H484
    • Gent, S.1    Skyschally, A.2    Kleinbongard, P.3    Heusch, G.4
  • 9
    • 13944271065 scopus 로고    scopus 로고
    • Pharmacological facilitation of primary percutaneous coronary intervention for acute myocardial infarction: is the slope of the curve the shape of the future?
    • COI: 1:CAS:528:DC%2BD2MXhsFGhu78%3D, PID: 15728169
    • Gersh BJ, Stone GW, White HD, Holmes DR (2005) Pharmacological facilitation of primary percutaneous coronary intervention for acute myocardial infarction: is the slope of the curve the shape of the future? JAMA 293:979–986. https://doi.org/10.1001/jama.293.8.979
    • (2005) JAMA , vol.293 , pp. 979-986
    • Gersh, B.J.1    Stone, G.W.2    White, H.D.3    Holmes, D.R.4
  • 12
    • 0345490687 scopus 로고    scopus 로고
    • Inhibiting mitochondrial permeability transition pore opening at reperfusion protects against ischaemia–reperfusion injury
    • COI: 1:CAS:528:DC%2BD3sXptlymsbo%3D, PID: 14659807
    • Hausenloy DJ, Duchen MR, Yellon DM (2003) Inhibiting mitochondrial permeability transition pore opening at reperfusion protects against ischaemia–reperfusion injury. Cardiovasc Res 60:617–625. https://doi.org/10.1016/j.cardiores.2003.09.025
    • (2003) Cardiovasc Res , vol.60 , pp. 617-625
    • Hausenloy, D.J.1    Duchen, M.R.2    Yellon, D.M.3
  • 14
    • 12344311866 scopus 로고    scopus 로고
    • Ischemic preconditioning protects by activating prosurvival kinases at reperfusion
    • COI: 1:CAS:528:DC%2BD2MXhsFels7o%3D, PID: 15358610
    • Hausenloy DJ, Tsang A, Mocanu MM, Yellon DM (2005) Ischemic preconditioning protects by activating prosurvival kinases at reperfusion. Am J Physiol Heart Circ Physiol 288:H971–H976. https://doi.org/10.1152/ajpheart.00374.2004
    • (2005) Am J Physiol Heart Circ Physiol , vol.288 , pp. H971-H976
    • Hausenloy, D.J.1    Tsang, A.2    Mocanu, M.M.3    Yellon, D.M.4
  • 15
    • 18844458509 scopus 로고    scopus 로고
    • The reperfusion injury salvage kinase pathway: a common target for both ischemic preconditioning and postconditioning
    • COI: 1:CAS:528:DC%2BD2MXktVOisLw%3D, PID: 15885573
    • Hausenloy DJ, Tsang A, Yellon DM (2005) The reperfusion injury salvage kinase pathway: a common target for both ischemic preconditioning and postconditioning. Trends Cardiovasc Med 15:69–75. https://doi.org/10.1016/j.tcm.2005.03.001
    • (2005) Trends Cardiovasc Med , vol.15 , pp. 69-75
    • Hausenloy, D.J.1    Tsang, A.2    Yellon, D.M.3
  • 16
    • 84924123511 scopus 로고    scopus 로고
    • Molecular basis of cardioprotection: signal transduction in ischemic pre-, post-, and remote conditioning
    • COI: 1:CAS:528:DC%2BC2MXis1Ojtr4%3D, PID: 25677517
    • Heusch G (2015) Molecular basis of cardioprotection: signal transduction in ischemic pre-, post-, and remote conditioning. Circ Res 116:674–699. https://doi.org/10.1161/CIRCRESAHA.116.305348
    • (2015) Circ Res , vol.116 , pp. 674-699
    • Heusch, G.1
  • 17
    • 85018173958 scopus 로고    scopus 로고
    • The pathophysiology of acute myocardial infarction and strategies of protection beyond reperfusion: a continual challenge
    • PID: 27354052
    • Heusch G, Gersh BJ (2017) The pathophysiology of acute myocardial infarction and strategies of protection beyond reperfusion: a continual challenge. Eur Heart J 38:774–784. https://doi.org/10.1093/eurheartj/ehw224
    • (2017) Eur Heart J , vol.38 , pp. 774-784
    • Heusch, G.1    Gersh, B.J.2
  • 18
    • 84855341208 scopus 로고    scopus 로고
    • STAT5 activation and cardioprotection by remote ischemic preconditioning in humans novelty and significance
    • COI: 1:CAS:528:DC%2BC38XivFWluw%3D%3D, PID: 22116817
    • Heusch G, Musiolik J, Kottenberg E, Peters J, Jakob H, Thielmann M (2012) STAT5 activation and cardioprotection by remote ischemic preconditioning in humans novelty and significance. Circ Res 110:111–115. https://doi.org/10.1161/CIRCRESAHA.111.259556
    • (2012) Circ Res , vol.110 , pp. 111-115
    • Heusch, G.1    Musiolik, J.2    Kottenberg, E.3    Peters, J.4    Jakob, H.5    Thielmann, M.6
  • 19
    • 0041932511 scopus 로고    scopus 로고
    • Additive protection of the ischemic heart ex vivo by combined treatment with -protein kinase C inhibitor and -protein kinase C activator
    • COI: 1:CAS:528:DC%2BD3sXmtFCisbs%3D, PID: 12860903
    • Inagaki K (2003) Additive protection of the ischemic heart ex vivo by combined treatment with -protein kinase C inhibitor and -protein kinase C activator. Circulation 108:869–875. https://doi.org/10.1161/01.CIR.0000081943.93653.73
    • (2003) Circulation , vol.108 , pp. 869-875
    • Inagaki, K.1
  • 20
    • 0035824907 scopus 로고    scopus 로고
    • Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling
    • COI: 1:CAS:528:DC%2BD3MXptFKmu7o%3D, PID: 11739285
    • Jonassen AK, Sack MN, Mjøs OD, Yellon DM (2001) Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling. Circ Res 89:1191–1198. https://doi.org/10.1161/hh2401.101385
    • (2001) Circ Res , vol.89 , pp. 1191-1198
    • Jonassen, A.K.1    Sack, M.N.2    Mjøs, O.D.3    Yellon, D.M.4
  • 21
    • 85027955586 scopus 로고    scopus 로고
    • Mechanisms of cell death in heart disease
    • COI: 1:CAS:528:DC%2BC38XpvV2msb0%3D, PID: 22596221
    • Konstantinidis K, Whelan RS, Kitsis RN (2012) Mechanisms of cell death in heart disease. Arterioscler Thromb Vasc Biol 32:1552–1562. https://doi.org/10.1161/ATVBAHA.111.224915
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 1552-1562
    • Konstantinidis, K.1    Whelan, R.S.2    Kitsis, R.N.3
  • 22
    • 71549129836 scopus 로고    scopus 로고
    • Ischaemic postconditioning protects against reperfusion injury via the SAFE pathway
    • COI: 1:CAS:528:DC%2BD1MXht1OrtLjI, PID: 19666677
    • Lacerda L, Somers S, Opie LH, Lecour S (2009) Ischaemic postconditioning protects against reperfusion injury via the SAFE pathway. Cardiovasc Res 84:201–208. https://doi.org/10.1093/cvr/cvp274
    • (2009) Cardiovasc Res , vol.84 , pp. 201-208
    • Lacerda, L.1    Somers, S.2    Opie, L.H.3    Lecour, S.4
  • 23
    • 63349089932 scopus 로고    scopus 로고
    • Multiple protective pathways against reperfusion injury: a SAFE path without Aktion?
    • COI: 1:CAS:528:DC%2BD1MXktFCht7o%3D, PID: 19318238
    • Lecour S (2009) Multiple protective pathways against reperfusion injury: a SAFE path without Aktion? J Mol Cell Cardiol 46:607–609. https://doi.org/10.1016/j.yjmcc.2009.01.003
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 607-609
    • Lecour, S.1
  • 24
    • 67349229765 scopus 로고    scopus 로고
    • Activation of the protective Survivor Activating Factor Enhancement (SAFE) pathway against reperfusion injury: does it go beyond the RISK pathway?
    • COI: 1:CAS:528:DC%2BD1MXms1Ortrw%3D, PID: 19344728
    • Lecour S (2009) Activation of the protective Survivor Activating Factor Enhancement (SAFE) pathway against reperfusion injury: does it go beyond the RISK pathway? J Mol Cell Cardiol 47:32–40. https://doi.org/10.1016/j.yjmcc.2009.03.019
    • (2009) J Mol Cell Cardiol , vol.47 , pp. 32-40
    • Lecour, S.1
  • 25
    • 33644876126 scopus 로고    scopus 로고
    • Pharmacological preconditioning with tumor necrosis factor-alpha activates signal transducer and activator of transcription-3 at reperfusion without involving classic prosurvival kinases (Akt and extracellular signal-regulated kinase)
    • COI: 1:CAS:528:DC%2BD2MXhtlSqurnJ, PID: 16344382
    • Lecour S, Suleman N, Deuchar GA, Somers S, Lacerda L, Huisamen B, Opie LH (2005) Pharmacological preconditioning with tumor necrosis factor-alpha activates signal transducer and activator of transcription-3 at reperfusion without involving classic prosurvival kinases (Akt and extracellular signal-regulated kinase). Circulation 112:3911–3918. https://doi.org/10.1161/CIRCULATIONAHA.105.581058
    • (2005) Circulation , vol.112 , pp. 3911-3918
    • Lecour, S.1    Suleman, N.2    Deuchar, G.A.3    Somers, S.4    Lacerda, L.5    Huisamen, B.6    Opie, L.H.7
  • 26
    • 1942501599 scopus 로고    scopus 로고
    • Differential contribution of necrosis and apoptosis in myocardial ischemia–reperfusion injury
    • COI: 1:CAS:528:DC%2BD2cXkt1entL0%3D, PID: 14715509
    • McCully JD, Wakiyama H, Hsieh Y-J, Jones M, Levitsky S (2004) Differential contribution of necrosis and apoptosis in myocardial ischemia–reperfusion injury. Am J Physiol Heart Circ Physiol 286:H1923–H1935. https://doi.org/10.1152/ajpheart.00935.2003
    • (2004) Am J Physiol Heart Circ Physiol , vol.286 , pp. H1923-H1935
    • McCully, J.D.1    Wakiyama, H.2    Hsieh, Y.-J.3    Jones, M.4    Levitsky, S.5
  • 27
    • 17144405293 scopus 로고    scopus 로고
    • Failure to protect the myocardium against ischemia/reperfusion injury after chronic atorvastatin treatment is recaptured by acute atorvastatin treatment: a potential role for phosphatase and tensin homolog deleted on chromosome ten?
    • COI: 1:CAS:528:DC%2BD2MXjtlagtL8%3D, PID: 15837263
    • Mensah K, Mocanu MM, Yellon DM (2005) Failure to protect the myocardium against ischemia/reperfusion injury after chronic atorvastatin treatment is recaptured by acute atorvastatin treatment: a potential role for phosphatase and tensin homolog deleted on chromosome ten? J Am Coll Cardiol 45:1287–1291. https://doi.org/10.1016/j.jacc.2005.01.021
    • (2005) J Am Coll Cardiol , vol.45 , pp. 1287-1291
    • Mensah, K.1    Mocanu, M.M.2    Yellon, D.M.3
  • 28
    • 0034016833 scopus 로고    scopus 로고
    • Caspase inhibition and limitation of myocardial infarct size: protection against lethal reperfusion injury
    • COI: 1:CAS:528:DC%2BD3cXjsl2mtLs%3D, PID: 10807653
    • Mocanu MM, Baxter GF, Yellon DM (2000) Caspase inhibition and limitation of myocardial infarct size: protection against lethal reperfusion injury. Br J Pharmacol 130:197–200. https://doi.org/10.1038/sj.bjp.0703336
    • (2000) Br J Pharmacol , vol.130 , pp. 197-200
    • Mocanu, M.M.1    Baxter, G.F.2    Yellon, D.M.3
  • 29
    • 0022970945 scopus 로고
    • Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium
    • COI: 1:STN:280:DyaL2s%2FivVKnuw%3D%3D, PID: 3769170
    • Murry CE, Jennings RB, Reimer KA (1986) Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74:1124–1136. https://doi.org/10.1161/01.CIR.74.5.1124
    • (1986) Circulation , vol.74 , pp. 1124-1136
    • Murry, C.E.1    Jennings, R.B.2    Reimer, K.A.3
  • 31
    • 85040973020 scopus 로고    scopus 로고
    • Role of PI3K in myocardial ischaemic preconditioning: mapping pro-survival cascades at the trigger phase and at reperfusion
    • Rossello X, Riquelme JA, Davidson SM, Yellon DM (2017) Role of PI3K in myocardial ischaemic preconditioning: mapping pro-survival cascades at the trigger phase and at reperfusion. J Cell Mol Med. https://doi.org/10.1111/jcmm.13394
    • (2017) J Cell Mol Med
    • Rossello, X.1    Riquelme, J.A.2    Davidson, S.M.3    Yellon, D.M.4
  • 33
    • 84976869433 scopus 로고    scopus 로고
    • A critical review on the translational journey of cardioprotective therapies!
    • PID: 27379920
    • Rossello X, Yellon DM (2016) A critical review on the translational journey of cardioprotective therapies! Int J Cardiol 220:176–184. https://doi.org/10.1016/j.ijcard.2016.06.131
    • (2016) Int J Cardiol , vol.220 , pp. 176-184
    • Rossello, X.1    Yellon, D.M.2
  • 34
    • 0036783616 scopus 로고    scopus 로고
    • Urocortin protects the heart from reperfusion injury via upregulation of p42/p44 MAPK signaling pathway
    • COI: 1:CAS:528:DC%2BD38XotVKit7s%3D, PID: 12234800
    • Schulman D, Latchman DS, Yellon DM (2002) Urocortin protects the heart from reperfusion injury via upregulation of p42/p44 MAPK signaling pathway. Am J Physiol Heart Circ Physiol 283:H1481–H1488. https://doi.org/10.1152/ajpheart.01089.2001
    • (2002) Am J Physiol Heart Circ Physiol , vol.283 , pp. H1481-H1488
    • Schulman, D.1    Latchman, D.S.2    Yellon, D.M.3
  • 35
    • 77955157002 scopus 로고    scopus 로고
    • Preconditioning the diabetic human myocardium
    • COI: 1:CAS:528:DC%2BC3cXhsFyrtLvP, PID: 19508386
    • Sivaraman V, Hausenloy DJ, Wynne AM, Yellon DM (2010) Preconditioning the diabetic human myocardium. J Cell Mol Med 14:1740–1746. https://doi.org/10.1111/j.1582-4934.2009.00796.x
    • (2010) J Cell Mol Med , vol.14 , pp. 1740-1746
    • Sivaraman, V.1    Hausenloy, D.J.2    Wynne, A.M.3    Yellon, D.M.4
  • 36
    • 59649114814 scopus 로고    scopus 로고
    • Ischemic postconditioning in pigs: no causal role for RISK activation
    • COI: 1:CAS:528:DC%2BD1cXhsFSmt7%2FJ, PID: 19038864
    • Skyschally A, van Caster P, Boengler K, Gres P, Musiolik J, Schilawa D, Schulz R, Heusch G (2009) Ischemic postconditioning in pigs: no causal role for RISK activation. Circ Res 104:15–18. https://doi.org/10.1161/CIRCRESAHA.108.186429
    • (2009) Circ Res , vol.104 , pp. 15-18
    • Skyschally, A.1    van Caster, P.2    Boengler, K.3    Gres, P.4    Musiolik, J.5    Schilawa, D.6    Schulz, R.7    Heusch, G.8
  • 37
    • 84937562950 scopus 로고    scopus 로고
    • Across-species transfer of protection by remote ischemic preconditioning with species-specific myocardial signal transduction by reperfusion injury salvage kinase and survival activating factor enhancement pathways novelty and significance
    • COI: 1:CAS:528:DC%2BC2MXhtFyjsbjM, PID: 26058828
    • Skyschally A, Gent S, Amanakis G, Schulte C, Kleinbongard P, Heusch G (2015) Across-species transfer of protection by remote ischemic preconditioning with species-specific myocardial signal transduction by reperfusion injury salvage kinase and survival activating factor enhancement pathways novelty and significance. Circ Res 117:279–288. https://doi.org/10.1161/CIRCRESAHA.117.306878
    • (2015) Circ Res , vol.117 , pp. 279-288
    • Skyschally, A.1    Gent, S.2    Amanakis, G.3    Schulte, C.4    Kleinbongard, P.5    Heusch, G.6
  • 38
    • 80052173847 scopus 로고    scopus 로고
    • Necroptosis, necrostatins and tissue injury
    • COI: 1:CAS:528:DC%2BC3MXht1ejt7jK, PID: 21564515
    • Smith CCT, Yellon DM (2011) Necroptosis, necrostatins and tissue injury. J Cell Mol Med 15:1797–1806. https://doi.org/10.1111/j.1582-4934.2011.01341.x
    • (2011) J Cell Mol Med , vol.15 , pp. 1797-1806
    • Smith, C.C.T.1    Yellon, D.M.2
  • 39
    • 45849120527 scopus 로고    scopus 로고
    • Dual activation of STAT-3 and Akt is required during the trigger phase of ischaemic preconditioning
    • COI: 1:CAS:528:DC%2BD1cXnt1Skt7Y%3D, PID: 18339648
    • Suleman N, Somers S, Smith R, Opie LH, Lecour SC (2008) Dual activation of STAT-3 and Akt is required during the trigger phase of ischaemic preconditioning. Cardiovasc Res 79:127–133. https://doi.org/10.1093/cvr/cvn067
    • (2008) Cardiovasc Res , vol.79 , pp. 127-133
    • Suleman, N.1    Somers, S.2    Smith, R.3    Opie, L.H.4    Lecour, S.C.5
  • 40
    • 84860792654 scopus 로고    scopus 로고
    • Role of the inflammasome in myocardial infarction
    • COI: 1:CAS:528:DC%2BC38Xnt1ajsLo%3D, PID: 22578238
    • Takahashi M (2011) Role of the inflammasome in myocardial infarction. Trends Cardiovasc Med 21:37–41. https://doi.org/10.1016/j.tcm.2012.02.002
    • (2011) Trends Cardiovasc Med , vol.21 , pp. 37-41
    • Takahashi, M.1
  • 41
    • 84957601532 scopus 로고    scopus 로고
    • Determinants of the efficacy of cardiac ischemic preconditioning: a systematic review and meta-analysis of animal studies
    • PID: 26580958
    • Wever KE, Hooijmans CR, Riksen NP, Sterenborg TB, Sena ES, Ritskes-Hoitinga M, Warlé MC (2015) Determinants of the efficacy of cardiac ischemic preconditioning: a systematic review and meta-analysis of animal studies. PLoS ONE 10:e0142021. https://doi.org/10.1371/journal.pone.0142021
    • (2015) PLoS ONE , vol.10
    • Wever, K.E.1    Hooijmans, C.R.2    Riksen, N.P.3    Sterenborg, T.B.4    Sena, E.S.5    Ritskes-Hoitinga, M.6    Warlé, M.C.7
  • 43
    • 0027301398 scopus 로고
    • Preconditioning the human myocardium
    • COI: 1:STN:280:DyaK3szitlKksA%3D%3D, PID: 8101304
    • Yellon DM, Alkhulaifi AM, Pugsley WB (1993) Preconditioning the human myocardium. Lancet 342:276–277. https://doi.org/10.1016/0140-6736(93)91819-8
    • (1993) Lancet , vol.342 , pp. 276-277
    • Yellon, D.M.1    Alkhulaifi, A.M.2    Pugsley, W.B.3
  • 44
    • 0033292942 scopus 로고    scopus 로고
    • Reperfusion injury revisited: is there a role for growth factor signaling in limiting lethal reperfusion injury?
    • COI: 1:CAS:528:DC%2BD3cXotlCrur4%3D, PID: 11094333
    • Yellon DM, Baxter GF (1999) Reperfusion injury revisited: is there a role for growth factor signaling in limiting lethal reperfusion injury? Trends Cardiovasc Med 9:245–249
    • (1999) Trends Cardiovasc Med , vol.9 , pp. 245-249
    • Yellon, D.M.1    Baxter, G.F.2
  • 45
    • 34548746306 scopus 로고    scopus 로고
    • Myocardial reperfusion injury
    • COI: 1:CAS:528:DC%2BD2sXhtVKgtLzF, PID: 17855673
    • Yellon DM, Hausenloy DJ (2007) Myocardial reperfusion injury. N Engl J Med 357:1121–1135. https://doi.org/10.1056/NEJMra071667
    • (2007) N Engl J Med , vol.357 , pp. 1121-1135
    • Yellon, D.M.1    Hausenloy, D.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.