메뉴 건너뛰기




Volumn 46, Issue 3, 2018, Pages 270-275

Correlation between hospital-level antibiotic consumption and incident health care facility-onset Clostridium difficile infection

Author keywords

Antibiotic use; Antimicrobial stewardship; Healthcare associated infections; Statistical model

Indexed keywords

AMIKACIN; ANTIBIOTIC AGENT; AZTREONAM; CARBAPENEM DERIVATIVE; CEFTRIAXONE; CIPROFLOXACIN; MEROPENEM; PIPERACILLIN PLUS TAZOBACTAM; QUINOLONE DERIVATIVE; SULTAMICILLIN; TOBRAMYCIN; ANTIINFECTIVE AGENT;

EID: 85034989462     PISSN: 01966553     EISSN: 15273296     Source Type: Journal    
DOI: 10.1016/j.ajic.2017.09.015     Document Type: Article
Times cited : (7)

References (27)
  • 1
    • 84930811216 scopus 로고    scopus 로고
    • Burden of Clostridium difficile infection in the United States
    • Lessa, F.C., Winston, L.G., McDonald, L.C., Emerging Infections Program CdST. Burden of Clostridium difficile infection in the United States. N Engl J Med 372 (2015), 2369–2370.
    • (2015) N Engl J Med , vol.372 , pp. 2369-2370
    • Lessa, F.C.1    Winston, L.G.2    McDonald, L.C.3
  • 2
    • 77951026738 scopus 로고    scopus 로고
    • Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA)
    • Cohen, S.H., Gerding, D.N., Johnson, S., Kelly, C.P., Loo, V.G., McDonald, L.C., et al. Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA). Infect Control Hosp Epidemiol 31 (2010), 431–455.
    • (2010) Infect Control Hosp Epidemiol , vol.31 , pp. 431-455
    • Cohen, S.H.1    Gerding, D.N.2    Johnson, S.3    Kelly, C.P.4    Loo, V.G.5    McDonald, L.C.6
  • 3
    • 84856959278 scopus 로고    scopus 로고
    • Time interval of increased risk for Clostridium difficile infection after exposure to antibiotics
    • Hensgens, M.P., Goorhuis, A., Dekkers, O.M., Kuijper, E.J., Time interval of increased risk for Clostridium difficile infection after exposure to antibiotics. J Antimicrob Chemother 67 (2012), 742–748.
    • (2012) J Antimicrob Chemother , vol.67 , pp. 742-748
    • Hensgens, M.P.1    Goorhuis, A.2    Dekkers, O.M.3    Kuijper, E.J.4
  • 4
    • 27444437759 scopus 로고    scopus 로고
    • Emergence of fluoroquinolones as the predominant risk factor for Clostridium difficile-associated diarrhea: a cohort study during an epidemic in Quebec
    • Pepin, J., Saheb, N., Coulombe, M.A., Alary, M.E., Corriveau, M.P., Authier, S., et al. Emergence of fluoroquinolones as the predominant risk factor for Clostridium difficile-associated diarrhea: a cohort study during an epidemic in Quebec. Clin Infect Dis 41 (2005), 1254–1260.
    • (2005) Clin Infect Dis , vol.41 , pp. 1254-1260
    • Pepin, J.1    Saheb, N.2    Coulombe, M.A.3    Alary, M.E.4    Corriveau, M.P.5    Authier, S.6
  • 5
    • 84884597711 scopus 로고    scopus 로고
    • Antibiotic Resistance Threats in the United States
    • Available from: (Accessed 13 June 2016)
    • Centers for Disease Control and Prevention (CDC), Antibiotic Resistance Threats in the United States. Available from: http://www.cdc.gov/drugresistance/threat-report-2013/, 2013. (Accessed 13 June 2016)
    • (2013)
  • 6
    • 85056371858 scopus 로고    scopus 로고
    • Vital Signs Technical Appendix: Estimating the Potential Reductions in Clostridium difficile Infection (CDI) among Patients when Antibiotic Use is Improved
    • Available from: (Accessed 13 June 2016)
    • Centers for Disease Control and Prevention (CDC), Vital Signs Technical Appendix: Estimating the Potential Reductions in Clostridium difficile Infection (CDI) among Patients when Antibiotic Use is Improved. Available from: http://www.cdc.gov/getsmart/healthcare/evidence/cdiff.html, 2015. (Accessed 13 June 2016)
    • (2015)
  • 7
    • 84896447804 scopus 로고    scopus 로고
    • Antibiotics and hospital-acquired Clostridium difficile infection: update of systematic review and meta-analysis
    • Slimings, C., Riley, T.V., Antibiotics and hospital-acquired Clostridium difficile infection: update of systematic review and meta-analysis. J Antimicrob Chemother 69 (2014), 881–891.
    • (2014) J Antimicrob Chemother , vol.69 , pp. 881-891
    • Slimings, C.1    Riley, T.V.2
  • 8
    • 39749120072 scopus 로고    scopus 로고
    • Antimicrobial-associated risk factors for Clostridium difficile infection
    • Owens, R.C. Jr, Donskey, C.J., Gaynes, R.P., Loo, V.G., Muto, C.A., Antimicrobial-associated risk factors for Clostridium difficile infection. Clin Infect Dis 46:Suppl 1 (2008), S19–S31.
    • (2008) Clin Infect Dis , vol.46 , pp. S19-S31
    • Owens, R.C.1    Donskey, C.J.2    Gaynes, R.P.3    Loo, V.G.4    Muto, C.A.5
  • 9
    • 84987816801 scopus 로고    scopus 로고
    • Making Health Care Safer: Antibiotic Rx in Hospitals: Proceed with Caution
    • Available from: (Accessed 13 June 2016)
    • Centers for Disease Control and Prevention (CDC), Making Health Care Safer: Antibiotic Rx in Hospitals: Proceed with Caution. Available from: http://www.cdc.gov/vitalsigns/antibiotic-prescribing-practices, 2014. (Accessed 13 June 2016)
    • (2014)
  • 10
    • 0037471542 scopus 로고    scopus 로고
    • Unnecessary use of antimicrobials in hospitalized patients: current patterns of misuse with an emphasis on the antianaerobic spectrum of activity
    • Hecker, M.T., Aron, D.C., Patel, N.P., Lehmann, M.K., Donskey, C.J., Unnecessary use of antimicrobials in hospitalized patients: current patterns of misuse with an emphasis on the antianaerobic spectrum of activity. Arch Intern Med 163 (2003), 972–978.
    • (2003) Arch Intern Med , vol.163 , pp. 972-978
    • Hecker, M.T.1    Aron, D.C.2    Patel, N.P.3    Lehmann, M.K.4    Donskey, C.J.5
  • 11
    • 85056369038 scopus 로고    scopus 로고
    • Get Smart for Healthcare
    • Available from: (Accessed 24 August 2016)
    • Centers for Disease Control and Prevention (CDC), Get Smart for Healthcare. Available from: http://www.cdc.gov/getsmart/healthcare/, 2016. (Accessed 24 August 2016)
    • (2016)
  • 12
    • 84872299193 scopus 로고    scopus 로고
    • Approaching zero: temporal effects of a restrictive antibiotic policy on hospital-acquired Clostridium difficile, extended-spectrum beta-lactamase-producing coliforms and meticillin-resistant Staphylococcus aureus
    • Dancer, S.J., Kirkpatrick, P., Corcoran, D.S., Christison, F., Farmer, D., Robertson, C., Approaching zero: temporal effects of a restrictive antibiotic policy on hospital-acquired Clostridium difficile, extended-spectrum beta-lactamase-producing coliforms and meticillin-resistant Staphylococcus aureus. Int J Antimicrob Agents 41 (2013), 137–142.
    • (2013) Int J Antimicrob Agents , vol.41 , pp. 137-142
    • Dancer, S.J.1    Kirkpatrick, P.2    Corcoran, D.S.3    Christison, F.4    Farmer, D.5    Robertson, C.6
  • 13
    • 34548267536 scopus 로고    scopus 로고
    • Impact of a reduction in the use of high-risk antibiotics on the course of an epidemic of Clostridium difficile-associated disease caused by the hypervirulent NAP1/027 strain
    • Valiquette, L., Cossette, B., Garant, M.P., Diab, H., Pepin, J., Impact of a reduction in the use of high-risk antibiotics on the course of an epidemic of Clostridium difficile-associated disease caused by the hypervirulent NAP1/027 strain. Clin Infect Dis 45:Suppl 2 (2007), S112–S121.
    • (2007) Clin Infect Dis , vol.45 , pp. S112-S121
    • Valiquette, L.1    Cossette, B.2    Garant, M.P.3    Diab, H.4    Pepin, J.5
  • 16
    • 84928188666 scopus 로고    scopus 로고
    • Hospital ward antibiotic prescribing and the risks of Clostridium difficile infection
    • Brown, K., Valenta, K., Fisman, D., Simor, A., Daneman, N., Hospital ward antibiotic prescribing and the risks of Clostridium difficile infection. JAMA Intern Med 175 (2015), 626–633.
    • (2015) JAMA Intern Med , vol.175 , pp. 626-633
    • Brown, K.1    Valenta, K.2    Fisman, D.3    Simor, A.4    Daneman, N.5
  • 18
    • 34848846245 scopus 로고    scopus 로고
    • Asymptomatic carriers are a potential source for transmission of epidemic and nonepidemic Clostridium difficile strains among long-term care facility residents
    • Riggs, M.M., Sethi, A.K., Zabarsky, T.F., Eckstein, E.C., Jump, R.L., Donskey, C.J., Asymptomatic carriers are a potential source for transmission of epidemic and nonepidemic Clostridium difficile strains among long-term care facility residents. Clin Infect Dis 45 (2007), 992–998.
    • (2007) Clin Infect Dis , vol.45 , pp. 992-998
    • Riggs, M.M.1    Sethi, A.K.2    Zabarsky, T.F.3    Eckstein, E.C.4    Jump, R.L.5    Donskey, C.J.6
  • 19
    • 72449194859 scopus 로고    scopus 로고
    • Persistence of skin contamination and environmental shedding of Clostridium difficile during and after treatment of C. difficile infection
    • Sethi, A.K., Al-Nassir, W.N., Nerandzic, M.M., Bobulsky, G.S., Donskey, C.J., Persistence of skin contamination and environmental shedding of Clostridium difficile during and after treatment of C. difficile infection. Infect Control Hosp Epidemiol 31 (2010), 21–27.
    • (2010) Infect Control Hosp Epidemiol , vol.31 , pp. 21-27
    • Sethi, A.K.1    Al-Nassir, W.N.2    Nerandzic, M.M.3    Bobulsky, G.S.4    Donskey, C.J.5
  • 20
    • 85056363692 scopus 로고    scopus 로고
    • Multidrug-Resistant Organism & Clostridium difficile Infection (MDRO/CDI) Module
    • Available from: (Accessed 13 June 2016)
    • Centers for Disease Control and Prevention (CDC), Multidrug-Resistant Organism & Clostridium difficile Infection (MDRO/CDI) Module. Available from: http://www.cdc.gov/nhsn/PDFs/pscManual/12pscMDRO_CDADcurrent.pdf, 2016. (Accessed 13 June 2016)
    • (2016)
  • 21
    • 85013633826 scopus 로고    scopus 로고
    • Antimicrobial Use and Resistance (AUR) Module
    • Available from: (Accessed 13 June 2016)
    • National Healthcare Safety Network (NHSN), Antimicrobial Use and Resistance (AUR) Module. Available from: http://www.cdc.gov/nhsn/PDFs/pscManual/11pscAURcurrent.pdf, 2016. (Accessed 13 June 2016)
    • (2016)
  • 24
    • 84864952631 scopus 로고    scopus 로고
    • Seasonality and temporal correlation between community antibiotic use and resistance in the United States
    • Sun, L., Klein, E.Y., Laxminarayan, R., Seasonality and temporal correlation between community antibiotic use and resistance in the United States. Clin Infect Dis 55 (2012), 687–694.
    • (2012) Clin Infect Dis , vol.55 , pp. 687-694
    • Sun, L.1    Klein, E.Y.2    Laxminarayan, R.3
  • 25
    • 84964313475 scopus 로고    scopus 로고
    • Antibiotic susceptibility of Clostridium difficile is similar worldwide over two decades despite widespread use of broad-spectrum antibiotics: an analysis done at the University Hospital of Zurich
    • Büchler, A.C., Rampini, S.K., Stelling, S., Ledergerber, B., Peter, S., Schweiger, A., et al. Antibiotic susceptibility of Clostridium difficile is similar worldwide over two decades despite widespread use of broad-spectrum antibiotics: an analysis done at the University Hospital of Zurich. BMC Infect Dis, 14, 2014, 607, 10.1186/s12879-014-0607-z.
    • (2014) BMC Infect Dis , vol.14 , pp. 607
    • Büchler, A.C.1    Rampini, S.K.2    Stelling, S.3    Ledergerber, B.4    Peter, S.5    Schweiger, A.6
  • 26
    • 66149143508 scopus 로고    scopus 로고
    • Quasiexperimental study of the effects of antibiotic use, gastric acid-suppressive agents, and infection control practices on the incidence of Clostridium difficile-associated diarrhea in hospitalized patients
    • Aldeyab, M.A., Harbarth, S., Vernaz, N., Kearney, M.P., Scott, M.G., Funston, C., et al. Quasiexperimental study of the effects of antibiotic use, gastric acid-suppressive agents, and infection control practices on the incidence of Clostridium difficile-associated diarrhea in hospitalized patients. Antimicrob Agents Chemother 53 (2009), 2082–2088.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 2082-2088
    • Aldeyab, M.A.1    Harbarth, S.2    Vernaz, N.3    Kearney, M.P.4    Scott, M.G.5    Funston, C.6
  • 27
    • 0035049158 scopus 로고    scopus 로고
    • Adjusting for multiple testing–when and how?
    • Bender, R., Lange, S., Adjusting for multiple testing–when and how?. J Clin Epidemiol 54 (2001), 343–349.
    • (2001) J Clin Epidemiol , vol.54 , pp. 343-349
    • Bender, R.1    Lange, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.