Cardiac βarrestin2 Improves Contractility and Adverse Remodeling in Heart Failure, But Is Underexpressed in Humans

Journal of the American College of Cardiology

Volumn 70, Issue 23, 2017, Pages 2948-2949

  McCrink, Katie A ^a   Maning, Jennifer ^a   Vu, Angela ^a   Jafferjee, Malika ^a   Marrero, Christine ^a   Brill, Ava ^a   Bathgate Siryk, Ashley ^a   Dabul, Samalia ^a   Koch, Walter J ^a   Lymperopoulos, Anastasios ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; BETA ARRESTIN 2; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; BETA ARRESTIN 1;

BETA ARRESTIN 2 GENE; CALCIUM TRANSPORT; GENE; GENE THERAPY; HEART FAILURE; HEART INFARCTION SIZE; HEART MUSCLE CONTRACTILITY; HUMAN; LETTER; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SERCA2A GENE; SUMOYLATION; BIOPSY; CARDIAC MUSCLE; HEART CONTRACTION; HEART STROKE VOLUME; HEART VENTRICLE REMODELING; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES;

BETA-ARRESTIN 1; BIOPSY; GENETIC THERAPY; HEART FAILURE; HUMANS; MYOCARDIAL CONTRACTION; MYOCARDIUM; STROKE VOLUME; VENTRICULAR REMODELING;

EID: 85034611863     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2017.10.008     Document Type: Letter

References (3)

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2. McCrink, K.A., Maning, J., Vu, A., et al. βarrestin2 improves post-myocardial infarction heart failure via SERCA2a-dependent positive inotropy in cardiomyocytes. Hypertension 70 (2017), 972–981.
3. Kho, C., Lee, A., Jeong, D., et al. SUMO1-dependent modulation of SERCA2a in heart failure. Nature 477 (2011), 601–605.