Frailty affects the initial treatment response and time to recovery of mobility in acutely ill older adults admitted to hospital

Age and Ageing

Volumn 46, Issue 6, 2017, Pages 920-925

  Hatheway, Oliver L ^a   Mitnitski, Arnold ^a   Rockwood, Kenneth ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Comprehensive geriatric assessment; Falls; Frailty; Frailty index; Geriatric giants; Hierarchical Assessment of Balance and Mobility (HABAM); Older people

Indexed keywords

ACUTE DISEASE; AGE; AGED; ARTICLE; CANADA; COHORT ANALYSIS; ENERGY RECOVERY; FEMALE; FRAILTY; GENERAL CONDITION IMPROVEMENT; GERIATRIC ASSESSMENT; GERIATRIC CARE; GERIATRIC PATIENT; HIERARCHICAL ASSESSMENT OF BALANCE AND MOBILITY; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HOSPITAL PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; PHYSICAL MOBILITY; PRIORITY JOURNAL; SCORING SYSTEM; TREATMENT RESPONSE; VERY ELDERLY; AGING; BODY EQUILIBRIUM; CONVALESCENCE; DECISION SUPPORT SYSTEM; FRAIL ELDERLY; LENGTH OF STAY; NOVA SCOTIA; ODDS RATIO; PATHOPHYSIOLOGY; PSYCHOLOGY; RISK FACTOR; TIME FACTOR; TREATMENT OUTCOME; WALKING DIFFICULTY;

ACUTE DISEASE; AGE FACTORS; AGED; AGED, 80 AND OVER; AGING; DECISION SUPPORT TECHNIQUES; FEMALE; FRAIL ELDERLY; FRAILTY; GERIATRIC ASSESSMENT; HUMANS; LENGTH OF STAY; MALE; MOBILITY LIMITATION; NOVA SCOTIA; ODDS RATIO; PATIENT ADMISSION; POSTURAL BALANCE; RECOVERY OF FUNCTION; RISK FACTORS; TIME FACTORS; TREATMENT OUTCOME;

EID: 85034260038     PISSN: 00020729     EISSN: 14682834     Source Type: Journal    
DOI: 10.1093/ageing/afw257     Document Type: Article

References (29)

1. Clegg A, Young J, Iliffe S et al. Frailty in elderly people. Lancet Lond Engl 2013; 381: 752-62
2. Elbourne HF, Hominick K, Mallery L et al. Characteristics of patients described as sub-acute in an acute care hospital. Can J Aging Rev Can Vieil 2013; 32: 203-8
3. Goldstein J, McVey J, Ackroyd-Stolarz S. The role of emergency medical services in geriatrics: bridging the gap between primary and acute care. Can J Emerg Med 2016; 18: 54-61
4. Young J, Gladman JRF, Forsyth DR et al. The second national audit of intermediate care. Age Ageing 2015; 44: 182-4
5. Zisberg A, Sinoff G, Agmon M et al. Even a small change can make a big difference: the case of in-hospital cognitive decline and new IADL dependency. Age Ageing 2016; 45: 500-4
6. Dent E, Chapman I, Howell S et al. Frailty and functional decline indices predict poor outcomes in hospitalised older people. Age Ageing 2014; 43: 477-84
7. Mitnitski A, Song X, Rockwood K. Assessing biological aging: the origin of deficit accumulation. Biogerontology 2013; 14: 709-17
8. Mitnitski AB, Mogilner AJ, Rockwood K. Accumulation of deficits as a proxy measure of aging. Scientific World J 2001; 1: 323-36
9. Fried LP, Tangen CM, Walston J et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 2001; 56: M146-56
10. Davis DHJ, Rockwood MRH, Mitnitski AB et al. Impairments in mobility and balance in relation to frailty. Arch Gerontol Geriatr 2011; 53: 79-83
11. Guadalupe-Grau A, Carnicero JA, Gómez-Cabello A et al. Association of regional muscle strength with mortality and hospitalisation in older people. Age Ageing 2015; 44: 790-5
12. Isaacs B. The Challenge of Geriatric Medicine. Oxford: Oxford University Press, 1992
13. Hubbard RE, Eeles EMP, Rockwood MRH et al. Assessing balance and mobility to track illness and recovery in older inpatients. J Gen Intern Med 2011; 26: 1471-8
14. MacKnight C, Rockwood K. A hierarchical assessment of balance and mobility. Age Ageing 1995; 24: 126-30
15. Rockwood K, Rockwood MRH, Andrew MK et al. Reliability of the hierarchical assessment of balance and mobility in frail older adults. J Am Geriatr Soc 2008; 56: 1213-7
16. Jones DM, Song X, Rockwood K. Operationalizing a frailty index from a standardized comprehensive geriatric assessment. J Am Geriatr Soc 2004; 52: 1929-33
17. Jones D, Song X, Mitnitski A et al. Evaluation of a frailty index based on a comprehensive geriatric assessment in a population based study of elderly Canadians. Aging Clin Exp Res 2005; 17: 465-71
18. Evans SJ, Sayers M, Mitnitski A et al. The risk of adverse outcomes in hospitalized older patients in relation to a frailty index based on a comprehensive geriatric assessment. Age Ageing 2014; 43: 127-32
19. Pocock LV, Ives A, Pring A et al. Factors associated with hospital deaths in the oldest old: a cross-sectional study. Age Ageing 2016; 45: 372-6
20. Bauer JM, Sieber CC. Sarcopenia and frailty: a clinician's controversial point of view. Exp Gerontol 2008; 43: 674-8
21. Rockwood K, Rockwood MRH, Mitnitski A. Physiological redundancy in older adults in relation to the change with age in the slope of a frailty index. J Am Geriatr Soc 2010; 58: 318-23
22. Gu D, Dupre ME, Sautter J et al. Frailty and mortality among Chinese at advanced ages. J Gerontol B Psychol Sci Soc Sci 2009; 64: 279-89
23. Henchoz Y, Meylan L, Goy R et al. Domains of importance to the quality of life of older people from two Swiss regions. Age Ageing 2015; 44: 979-85
24. Portegijs E, Rantakokko M, Viljanen A et al. Is frailty associated with life-space mobility and perceived autonomy in participation outdoors? A longitudinal study. Age Ageing 2016; 45: 550-3
25. Gothe NP, Fanning J, Awick E et al. Executive function processes predict mobility outcomes in older adults. J Am Geriatr Soc 2014; 62: 285-90
26. Li H, Manwani B, Leng SX. Frailty, inflammation, and immunity. Aging Dis 2011; 2: 466-73
27. Christensen K, Johnson TE, Vaupel JW. The quest for genetic determinants of human longevity: challenges and insights. Nat Rev Genet 2006; 7: 436-48
28. Yashin AI, Arbeev KG, Wu D et al. How lifespan associated genes modulate aging changes: lessons from analysis of longitudinal data. Front Genet 2013; 4: 3
29. Gladman JRF, Conroy SP, Ranhoff AH et al. New horizons in the implementation and research of comprehensive geriatric assessment: knowing, doing and the 'know-do' gap. Age Ageing 2016; 45: 194-200