Single measurement of plasminogen activator inhibitor-1 in sepsis: Is it useful for evaluating the severity or prognosis of sepsis?

Journal of Intensive Care

Volumn 5, Issue 1, 2017, Pages

  Koyama, Kansuke ^a   Nunomiya, Shin ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Biomarker; Coagulopathy; Plasminogen activator inhibitor 1; Prognosis; Sepsis

Indexed keywords

BIOLOGICAL MARKER; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN C;

BLOOD CLOTTING DISORDER; DISEASE SEVERITY; ENDOTHELIUM CELL; HUMAN; INFLAMMATION; LETTER; PRIORITY JOURNAL; PROGNOSIS; SEPSIS;

EID: 85034022944     PISSN: None     EISSN: 20520492     Source Type: Journal    
DOI: 10.1186/s40560-017-0259-3     Document Type: Letter

References (5)

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2. Iba T, Thachil J. Clinical significance of measuring plasminogen activator inhibitor-1 in sepsis. J Intensive Care. 2017;5:56.
3. Lorente JA, Garcia-Frade LJ, Landin L, de Pablo R, Torrado C, Renes E, et al. Time course of hemostatic abnormalities in sepsis and its relation to outcome. Chest. 1993;103:1536-42.
4. Kinasewitz GT, Yan SB, Basson B, Comp P, Russell JA, Cariou A, et al. Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism. Crit Care. 2004;8:R82.
5. Koyama K, Madoiwa S, Nunomiya S, Koinuma T, Wada M, Sakata A, et al. Combination of thrombin-antithrombin complex, plasminogen activator inhibitor-1, and protein C activity for early identification of severe coagulopathy in initial phase of sepsis: a prospective observational study. Crit Care. 2014;18:R13.