Bacterial and human cell mutagenicity and mouse lung tumorigenicity of the oxygenated polynuclear aromatic hydrocarbon phenalenone

Fundamental and Applied Toxicology

Volumn 33, Issue 2, 1996, Pages 212-219

  Wang, Jia Sheng ^a,b   Busby Jr , William F ^a,c  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FOSSIL FUEL; POLYCYCLIC AROMATIC HYDROCARBON;

AIR POLLUTANT; ANIMAL EXPERIMENT; ARTICLE; CARCINOGENICITY; CELL LINE; COMBUSTION; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; FEMALE; HUMAN; HUMAN CELL; LUNG TUMOR; MALE; MOUSE; MUTAGENICITY; MUTATION; NONHUMAN; SEX DIFFERENCE;

ANIMALIA; BACTERIA (MICROORGANISMS); OXY; SALMONELLA; SALMONELLA TYPHIMURIUM; TYPHIMURIUM;

EID: 85033071441     PISSN: 02720590     EISSN: None     Source Type: Journal    
DOI: 10.1006/faat.1996.0158     Document Type: Article

References (30)

1. Aceves, M., and Grimalt, J. O. (1992). Gas chromatographic screening of organic compounds in urban aerosols. Selectivity effects in semi-polar columns. J. Chromatog. 607, 261-270.
2. Alsberg, T., Strandell, M., Westerholm, R., and Stenberg, U. (1985). Fractionation and chemical analysis of gasoline exhaust paniculate extracts in connection with biological testing. Environ. Int. 11, 249-257.
3. Amin, S., Hecht, S. S., LaVoie, E., and Hoffmann, D. (1979). Synthesis and mutagenicity of 5,11-dimethylchrysene and some methyl-oxidized derivatives of 5-methylchrysene. J. Med. Chem. 22, 1336-1340.
4. Busby, W. F., Jr., Goldman, M. E., Newberne, P. M., and Wogan, G. N. (1984). Tumorigenicity of fluoranthene in a newborn mouse lung adenoma bioassay. Carcinogenesis 5, 1311-1316.
5. Busby, W. F., Jr., Penman, B. W., and Crespi, C. L. (1994a). Human cell mutagenicity of mono-and dinitropyrenes in metabolically competent MCL-5 cells. Mutat. Res. 322, 233-242.
6. Busby, W. F., Jr., Smith, H., Bishop, W. W., and Thilly, W. G. (1994b). Mutagenicity of mono-and dinitropyrenes in the Salmonella typhimurium TM677 forward mutation assay. Mutat. Res. 322, 221-232.
7. Busby, W. F., Jr., Smith, H., Crespi, C. L., and Penman, B. W. (1995). Mutagenicity of benzo[a]pyrene and dibenzopyrenes in the Salmonella typhimurium TM677 and the MCL-5 human cell forward mutation assays. Mutat. Res. 342,9-16.
8. Busby, W. F., Jr., Smith, H., Crespi, C. L., Penman, B. W., and Lafleur, A. L. (1996). Mutagenicity of the atmospheric transformation products 2-nitrofluoranthene and 2-nitrodibenzopyranone in Salmonella and human cell forward mutation assays. Mutat. Res., in press.
9. Busby, W. F., Jr., Stevens, E. K., Kellenbach, E. R., Cornelisse, J., and Lugtenburg, J. (1988). Dose-response relationships of the tumorigenicity of cyclopenta[cd]pyrene, benzo[a]pyrene and 6-nitrochrysene in a newborn mouse lung adenoma bioassay. Carcinogenesis 9, 741-746.
10. Busby, W. F., Jr., Stevens, E. K., Martin, C. N., Chow, F. L., and Garner, R. C. (1989). Comparative lung tumorigenicity of parent and mononitropolynuclear aromatic hydrocarbons in the BLU:Ha newborn mouse assay. Toxicol. Appl. Pharmacol. 99, 555-563.
11. Chiu, K.-S., Walsh, P. M., Beer, J. M., and Biemann, K. (1983). Polynuclear aromatic compounds in fluidized bed combustion of bituminous coal, subbituminous coal, and oil shale. In Polynuclear Aromatic Hydrocarbons: Formation, Metabolism and Measurement (M. Cooke and A. J. Dennis, Eds.), pp. 319-339. Battelle Press, Columbus.
12. Crespi, C. L., Gonzalez, F. J., Steimel, D. T., Turner, T. R., Gelboin, H. V., Penman, B. W., and Langenbach R. (1991). A metabolically competent human cell line expressing five cDNAs encoding procarcinogen-activating enzymes: Application to mutagenicity testing. Chem. Res. Toxicol. 4, 566-572.
13. Furth, E. E., Thilly, W. G., Penman, B. W., Liber, H. L., and Rand, W. M. (1981). Quantitative assay for mutation in diploid human lymphoblasts using microtiter plates. Anal. Biochem. 110, 1-8.
14. Kaden, D. A., Hites, R. A., and Thilly, W. G. (1979). Mutagenicity of soot and associated polycyclic aromatic hydrocarbons to Salmonella typhimurium. Cancer Res. 39, 4152-4159.
15. Kapitulnik, J., Wislocki, P. G., Levin, W., Yagi, H., Jerina, D. M., and Conney, A. H. (1978). Tumorigenicity studies with diol-epoxides of benzo[a]pyrene which indicate that (±)-trans-7β,8α-dihydroxy-9α, 10α-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene is an ultimate carcinogen in newborn mice. Cancer Res. 38, 354-358.
16. Leary, J. A., Biemann, K., Lafleur, A. L., Kruzel, E. L., Prado, G. P., Longwell, J. P., and Peters, W. A. (1987). Chemical and toxicological characterization of residential oil burner emissions: I. Yields and chemical characterization of extractables from combustion of No. 2 fuel oil at different Bacharach smoke numbers and firing cycles. Environ. Health Perspect. 73, 223-234.
17. Leary, J. A., Lafleur, A. L., Liber, H. L., and Biemann, K. (1983). Chemical and toxicologic characterization of fossil fuel combustion product phenalen-1-one. Anal. Chem. 55, 758-761.
18. Lies, K.-H., Hartung, A., Postulka, A., Gring, H., and Schulze, H. (1986). Composition of diesel exhaust with particular reference to particle bound organics including formation of artifacts. In Carcinogenic and Mutagenic Effects of Diesel Engine Exhaust (N. Ishinishi, A., Koizumi, R. O. McClellan, and W. Stöber, Eds.), pp. 65-82. Elsevier, New York.
19. Marshman, S. J. (1990). Liquid Chromatographic determination of phenalenones in middle distillate fuels. Fuel 69, 1558-1560.
20. Pedley, J. F., Hiley, R. W., and Hancock, R. A. (1988). Storage stability of petroleum-derived diesel fuel: 3. Identification of compounds involved in sediment formation. Fuel 67, 1124-1130.
21. Penman, B. W., and Crespi, C. L. (1987). Analysis of human lymphoblast mutation assays by using historical negative control data bases. Environ. Mol. Mutagen. 10, 35-60.
22. Penman, B. W., Chen, L., Gelboin, H. V., Gonzalez, F. G., and Crespi, C. L. (1994). Development of a human lymphoblastoid cell line constitutively expressing human CYP1A1 cDNA: Substrate specificity with model substrates and promutagens. Carcinogenesis 15, 1931-1937.
23. Peto, R., Pike, M. C., Day, N. E., Gray, R. G., Lee, P. N., Parish, S., Peto, J., Richards, S., and Wahrendorf, J. (1980). Guidelines for simple sensitive significance tests for carcinogenic effects in long-term animal experiments. In Long-Term and Short-Term Screening Assays for Carcinogens: A Critical Appraisal. IARC Monographs, Supplement 2, pp. 311-426. International Agency for Research on Cancer, Lyon.
24. Pitts, J. N., Jr., Lokensgard, D. M., Karger, W., Fisher, T. S., Mejia, V., Schuler, J. J., Scorziell, G. M., and Katzenstein, Y. A. (1982). Mutagens in diesel exhaust paniculate. Identification and direct activities of 6-nitrobenzo[a]pyrene, 9-nitroanthracene, 1-nitropyrene and 5H-phenanthro[4,5-bcd]pyran-5-one. Mutat. Res. 103, 241-249.
25. Ramdahl, T. (1983). Polycyclic aromatic ketones in environmental samples. Environ. Sci. Technol. 17, 666-670.
26. Rannug, U., and Sundvall, A. (1985). Mutagenic properties of gasoline exhausts. Environ. Int. 11, 303-309.
27. Rogge, W. F., Hildemann, L. M., Mazurek, M. A., Cass, G. R., and Simoneit, B. R. T. (1993). Sources of fine organic aerosol. 5. Natural gas home appliances. Environ. Sci. Technol. 27, 2736-2744.
28. Stanley, T. W., Morgan, M. J., and Meeker, J. E. (1969). Rapid estimation of 7H-benz[de]anthracen-7-one and phenalen-1-one in organic extracts of airborne particulates from 3-hour sequential air samples. Environ. Sci. Technol. 3, 1198-1200.
29. Strandell, M., Zakrisson, S., Alsberg, T., Westerholm, R., Winquist, L., and Rannug, U. (1994). Chemical analysis and biological testing of a polar fraction of ambient air, diesel engine, and gasoline engine exhaust particulate extracts. Environ. Health Perspect. 102(Suppl. 4), 85-92.
30. Winters, K., Batterton, J. C., and Van Baalen, C. (1977). Phenalen-1-one: Occurrence in a fuel oil and toxicity to microalgae. Environ. Sci. Technol. 11, 270-272.