Effect of bile duct ligation and unilateral nephrectomy on brain concentration and convulsant potential of the quinolone antibacterial agent levofloxacin in rats

Fundamental and Applied Toxicology

Volumn 29, Issue 2, 1996, Pages 280-286

  Akahane, Kazumi ^a   Ohkawara, Satoshi ^a   Nomura, Mamoru ^a   Kato, Michiyuki ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

LEVOFLOXACIN; QUINOLINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILE DUCT LIGATION; CONTROLLED STUDY; CONVULSION; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG URINE LEVEL; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; RAT; UNINEPHRECTOMY;

EID: 85033065099     PISSN: 02720590     EISSN: None     Source Type: Journal    
DOI: 10.1006/faat.1996.0032     Document Type: Article

References (27)

1. Akahane, K., Sekiguchi, M., Une, T., and Osada, Y. (1989). Structure-epileptogenicity relationship of quinolones with special reference to their interaction with γ-aminobutyric acid receptor sites. Antimicrob. Agents Chemother. 33, 1704-1708.
2. Akahane, K., Kato, M., and Takayama, S. (1993). Involvement of inhibitory and excitatory neurotransmitters in levofloxacin- and ciprofloxacin-induced convulsions in mice. Antimicrob. Agents Chemother. 37, 1764-1770.
3. Anastasio, G. D., Menscery, D., and Little, J. M., Jr. (1988). Norfloxacin and seizures. Ann. Intern. Med. 109, 169-170.
4. Aoki, H., Okazaki, O., Kurata, T., Shintani, S., Tachizawa, H., and Hakusui, H. (1991). The pharmacokinetics of DR-3355(I): Absorption, distribution and excretion after a single oral administration to rats. Xenobiotic Metab. Dispos. 6, 793-803.
5. Arcieri, G., Griffith, E., Gruenwaldt, G., Heyd, A., O'Brien, B., Backer, N., and August, R. (1987). Ciprofloxacin: An update on clinical experience. Am. J. Med. 82(Suppl. 4A), 381-386.
6. Chiccarelli, F. S., Eisner, H. J., and Van Lear, G. E. (1980). Metabolic and pharmacokinetic studies with fenbufen in man. Arzneim.-Forsch. 30, 727-732.
7. Dodd, P. R., Davies, L. P., Watson, W. E. J., Nielsen, B., Dyer, J. A., Wong, L. S., and Johnston, G. A. R. (1989). Neurochemica studies on quinolone antibiotics Effects on glutamate, GABA and adenosine systems in mammalian CNS. Pharmacol. Toxicol. 64, 404-411.
8. Dodo, M., Nakatsuji, K., Miura, Y., Hori, M., Furukawa, K., Oka, M., and Ito, T. (1991). General pharmacology of sparfloxacin, a new quinolone antibacterial agent. 1. Effects on the centra nervous system. Pharmacometrics 41, 147-155.
9. Halliwell, R. F., Davey, P. G., and Lambert, J. J. (1991). The effects of qui nol ones and NSAI Ds upon GAVA-evoked currents recorded from rat dorsal root ganglion neurones. J. Antimicrob. Chemother. 27, 209-218.
10. Hori, S., Shimada, J., Saito, A., Matsuda, M., and Miyahara, T. (1989). Comparison of the inhibitory effects of new quinoloneson γ-aminobutyric acid receptor binding in the presence of antiinflammatory drugs Rev. Infect. Dis 11(Suppl. 5), S1397-S1398.
11. Ichikawa, N., Naora, K., Hayashibara, M., Katagiri, Y., and Iwamoto, K. (1992). Effect of fenbufen on the entry of new quinolones, norfloxacin and ofloxacin, into the central nervous system in rats. J. Pharm. Pharmacol. 44, 915-920.
12. Kohno, K., Nozaki, M., Takeda, N., and Tsurumi, K. (1994). Neuroexcitable effects of levofloxacin, a novel quinolone antibacterial, in concomitant use of non-steroidal anti-inflammatory drugs The comparative study with other quinolones. Jpn. Pharmacol. Ther. 22, 1811-1821.
13. Motomura, M., Kataoka, Y., Takeo, G., Shibayama, K., Ohishi, K., Nakamura, T., Niwa, M., Tsujihara, M., and Nagataki, S. (1991). Hippocampus and frontal cortex are the potential mediatory sites for convulsions induced by new quinolones and non-steroidal anti-inflammatory drugs Int. J. Clin. Pharmacol. Ther. Toxicol. 29, 223-227.
14. Murayama, S., Suzuki, T., Hara, Y., Tamagawa, M., and Kakizaki, K. (1987). Unusual central action of new quinolone group of antimicrobials. Jpn. J. Pharmacol. 43(Suppl.), 60.
15. Naora, K., Katagiri, Y., Ichikawa, N., Hayashibara, M., and Iwamoto, K. (1990). A possible reduction in the renal clearance of ciprofloxacin by fenbufen in rats J. Pharm. Pharmacol. 42, 704-707.
16. Naora, K., Katagiri, Y., Ichikawa, N., Hayashibara, M., and Iwamoto, K. (1991). Enhanced entry of ciprofloxacin into the rat central nervous system induced by fenbufen. J. Pharmacol. Exp. Ther. 258, 1033-1037.
17. Nozaki, M., Takeda, N., Tanaka, K., Niwa, M., Inazumi, K., Kaido, T., Tsurumi, K., and Fujimura, H. (1991). Convulsions induced by concomitant use of new quinolone antibacterial and NSAID. Jpn. J. Inflammation 11, 343-348.
18. Roussel, J. P., Tapia-Arancibia, L., Jourdan, J., and Astier, H. (1988). Effect of norfloxacin, a new quinolone, on GABA modulation of TRH-induced TSH release from perfused rat pituitaries Acta Endocrinol. (Copenhagen) 119, 481-487.
19. Segev, S., Rehavi, M., and Rubenstein, E. (1988). Quinolones, theophylline, and diclofenac interactions with γ-aminobutyric acid receptor. Antimicrob. Agents Chemother. 32, 1624-1626.
20. Simpson, K. J., and Brodie, M. J. (1985). Convulsions related to enoxacin. Lancet 2, 161.
21. Suzuki, T., Hara, Y., Tamagawa, M., Kakizaki, K., and Murayama, S. (1992). Effects of the combination of new quinolones and a nonsteroidal anti-inflammatory drug, fenbufen, on the EEG of rabbits. Folia Pharmacol. Jpn. 99, 45-54.
22. Takeo, G., Shibuya, N., Motomura, M., Kanazawa, H., and Shishido, H. (1989). A new DNA gyrase inhibitor induces convulsions A case report and animal experiments. Chemotherapy (Tokyo) 37, 1154-1159.
23. Tsujii, A., Sato, H., Kume, Y., Tamai, I., Okezaki, E., Nagata, O., and Kato, H. (1988a). Inhibitory effects of quinolone antibacterial agents on gamma-aminobutyric acid binding to receptor sites in rat brain membranes. Antimicrob. Agents Chemother. 32, 190-194.
24. Tsujii, A., Sato, H., Okazaki, E., Nagata, O., and Kato, H. (1988b). Effect of the antiinflammatory agent fenbufen on the quinolone-induced inhibition of γ-aminobutyric acid binding to rat brain membranes in vitro. Biochem. Pharmacol. 37, 4408-4411.
25. A receptor inhibition required for quinolone-induced convulsions in mice. J. Antimicrob. Chemother. 34, 737-746.
26. Wolfson, J. S., and Hooper, D. C. (1988). Norfloxacin: A new targeted fluoroquinol one anti bacterial agent. Ann. Intern. Med. 108, 238-251.
27. Yamamoto, K., Naitoh, Y., Inoue, Y., and Yoshimura, K. (1988). Seizure discharges induced by the combination of new quinolinecarboxylic acid antimicrobial drugs and non-steroidal anti-inflammatory drugs Effect of NY-198 on the central nervous system. Chemotherapy (Tokyo) 36(Suppl. 2), 300-324.