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Volumn 32, Issue 1, 1996, Pages 53-65

Carcinogenicity of the anticancer topoisomerase inhibitor, amsacrine, in Wistar rats

Author keywords

[No Author keywords available]

Indexed keywords

AMSACRINE;

EID: 85033062532     PISSN: 02720590     EISSN: None     Source Type: Journal    
DOI: 10.1006/faat.1996.0106     Document Type: Article
Times cited : (7)

References (63)
  • 1
    • 0025009192 scopus 로고
    • Chemical carcinogenesis: Too many rodent carcinogens
    • Ames, B. N., and Gold, L. S. (1990). Chemical carcinogenesis: Too many rodent carcinogens. Proc. Natl. Acad. Sci. USA 87, 7772-7776.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 7772-7776
    • Ames, B.N.1    Gold, L.S.2
  • 2
    • 0024507201 scopus 로고
    • The production of chromosomal alterations in human lymphocytes by drugs known to interfere with the activity of DNA topoisomerase II. I. m-Amsa
    • Andersson, H. C., and Kihlman, B. A. (1989). The production of chromosomal alterations in human lymphocytes by drugs known to interfere with the activity of DNA topoisomerase II. I. m-Amsa. Carcinogenesis 10, 123-130.
    • (1989) Carcinogenesis , vol.10 , pp. 123-130
    • Andersson, H.C.1    Kihlman, B.A.2
  • 3
    • 0024955726 scopus 로고
    • A special role for amsacrine in the treatment of acute leukemia
    • Arlin, Z. A. (1989). A special role for amsacrine in the treatment of acute leukemia. Cancer Invest. 7, 607-609.
    • (1989) Cancer Invest. , vol.7 , pp. 607-609
    • Arlin, Z.A.1
  • 6
    • 0018966583 scopus 로고
    • Phase I and II trial of 4′-(9-acridinylamino)methanesulfon-m-anisidide in patients with acute leukemia
    • Arlin, Z. A., Sklaroff, R. B., Gee, T. S., Kempin, S. J., Howard, J., Clarkson, B. D., and Young, C. W. (1980). Phase I and II trial of 4′-(9-acridinylamino)methanesulfon-m-anisidide in patients with acute leukemia. Cancer Res. 40, 3304-3306.
    • (1980) Cancer Res. , vol.40 , pp. 3304-3306
    • Arlin, Z.A.1    Sklaroff, R.B.2    Gee, T.S.3    Kempin, S.J.4    Howard, J.5    Clarkson, B.D.6    Young, C.W.7
  • 9
    • 0023856614 scopus 로고
    • Chemical structure, salmonella mutagenicity and extent of carcinogenicity as indicators of genotoxic carcinogenesis among 222 chemicals tested in rodents by the U.S. NCI/ NTP
    • Ashby, J., and Tennant, R. W. (1988). Chemical structure, Salmonella mutagenicity and extent of carcinogenicity as indicators of genotoxic carcinogenesis among 222 chemicals tested in rodents by the U.S. NCI/ NTP. Mutat. Res. 204, 17-115.
    • (1988) Mutat. Res. , vol.204 , pp. 17-115
    • Ashby, J.1    Tennant, R.W.2
  • 11
    • 0028308415 scopus 로고
    • Frequency of spontaneous tumours in Wistar rats in 2-year studies
    • Bombard, E., and Rinke, M. (1994). Frequency of spontaneous tumours in Wistar rats in 2-year studies. Exp. Toxicol. Pathol. 46, 17-29.
    • (1994) Exp. Toxicol. Pathol. , vol.46 , pp. 17-29
    • Bombard, E.1    Rinke, M.2
  • 12
    • 0025820646 scopus 로고
    • A critique of the use of the maximum tolerated dose in bioassays to assess cancer risks from chemicals
    • Carr, C. J., and Kolbye, A. C. (1991). A critique of the use of the maximum tolerated dose in bioassays to assess cancer risks from chemicals. Regul. Toxicol. Pharmacol. 14, 78-87.
    • (1991) Regul. Toxicol. Pharmacol. , vol.14 , pp. 78-87
    • Carr, C.J.1    Kolbye, A.C.2
  • 13
    • 0026344785 scopus 로고
    • An appreciation of the maximum tolerated dose: An inadequately precise decision point in designing a carcinogenesis bioassay?
    • Clayson, D. B., Iverson, F., and Mueller, R. (1991). An appreciation of the maximum tolerated dose: An inadequately precise decision point in designing a carcinogenesis bioassay? Teratogen. Carcinog. Mutagen. 11, 279-296.
    • (1991) Teratogen. Carcinog. Mutagen. , vol.11 , pp. 279-296
    • Clayson, D.B.1    Iverson, F.2    Mueller, R.3
  • 15
    • 0026450056 scopus 로고
    • Immunohistochemical and ultrastructural characterization of granular cell tumors of the female reproductive tract in two aged Wistar rats
    • Courtney, C. L., Hawkins, K. L., Meierhenry, E. F., and Graziano, M. J. (1992b). Immunohistochemical and ultrastructural characterization of granular cell tumors of the female reproductive tract in two aged Wistar rats. Vet. Pathol. 29, 86-89.
    • (1992) Vet. Pathol. , vol.29 , pp. 86-89
    • Courtney, C.L.1    Hawkins, K.L.2    Meierhenry, E.F.3    Graziano, M.J.4
  • 16
    • 0023883103 scopus 로고
    • Topoisomerase II-mediated DNA damage produced by 4′-(9-acridinylamino)-methanesulfon-m-anisidide and related acridines in L1210 cells and isolated nuclei: Relation to cytotoxicity
    • Covey, J. M., Kohn, K. W., Kerrigan, D., Tilchen, E. J., and Pommier, Y. (1988). Topoisomerase II-mediated DNA damage produced by 4′-(9-acridinylamino)-methanesulfon-m-anisidide and related acridines in L1210 cells and isolated nuclei: Relation to cytotoxicity. Cancer Res. 48, 860-865.
    • (1988) Cancer Res. , vol.48 , pp. 860-865
    • Covey, J.M.1    Kohn, K.W.2    Kerrigan, D.3    Tilchen, E.J.4    Pommier, Y.5
  • 17
    • 0027292407 scopus 로고
    • DNA topoisomerase I and II as targets for rational design of new anticancer drugs
    • Cummings, J., and Smyth, J. F. (1993). DNA topoisomerase I and II as targets for rational design of new anticancer drugs. Ann. Oncol. 4, 533-543.
    • (1993) Ann. Oncol. , vol.4 , pp. 533-543
    • Cummings, J.1    Smyth, J.F.2
  • 18
    • 0017592982 scopus 로고
    • The pharmacologic disposition of 4′-(9-acridinylamino)methanesulfon-m-anisidide in mice and rats
    • Cysyk, R. L., Shoemaker, D., and Adamson, R. H. (1977). The pharmacologic disposition of 4′-(9-acridinylamino)methanesulfon-m-anisidide in mice and rats. Drug Metab. Disp. 5, 579-590.
    • (1977) Drug Metab. Disp. , vol.5 , pp. 579-590
    • Cysyk, R.L.1    Shoemaker, D.2    Adamson, R.H.3
  • 19
    • 0025264490 scopus 로고
    • Intermediate-dose cytosine arabinoside and amsacrine
    • Dekker, A. W., Nieuwenhuis, H. K., and Verdonck, L. F. (1990). Intermediate-dose cytosine arabinoside and amsacrine. Cancer 65, 1891-1894.
    • (1990) Cancer , vol.65 , pp. 1891-1894
    • Dekker, A.W.1    Nieuwenhuis, H.K.2    Verdonck, L.F.3
  • 20
    • 0023403294 scopus 로고
    • Mutagenicity of m-AMSA and o-AMSA in mammalian cells due to clastogenic mechanism: Possible role of topoisomerase
    • DeMarini, D. M., Doerr, C. L., Meyer, M. K., Brock, K. H., Hozier, J., and Moore, R. M. (1987). Mutagenicity of m-AMSA and o-AMSA in mammalian cells due to clastogenic mechanism: Possible role of topoisomerase. Mutagenesis 2, 349-355.
    • (1987) Mutagenesis , vol.2 , pp. 349-355
    • DeMarini, D.M.1    Doerr, C.L.2    Meyer, M.K.3    Brock, K.H.4    Hozier, J.5    Moore, R.M.6
  • 21
    • 0025768698 scopus 로고
    • The genetic toxicology of acridines
    • Ferguson, L. R., and Denny, W. A. (1991). The genetic toxicology of acridines. Mutat. Res. 258, 123-160.
    • (1991) Mutat. Res. , vol.258 , pp. 123-160
    • Ferguson, L.R.1    Denny, W.A.2
  • 22
    • 0013909023 scopus 로고
    • Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey, and man
    • Freireich, E. J., Gehan, E. A., Rall, D. P., Schmidt, L. H., and Skipper, H. E. (1966). Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey, and man. Cancer Chemother. Rep. 50, 219-244.
    • (1966) Cancer Chemother. Rep. , vol.50 , pp. 219-244
    • Freireich, E.J.1    Gehan, E.A.2    Rall, D.P.3    Schmidt, L.H.4    Skipper, H.E.5
  • 23
    • 0025787478 scopus 로고
    • Five-day 4′-(9-acridinylamino)methanesulphon-m-anisidide and intermediate-dose cytosine arabinoside in high-risk relapsing or refractory acute myeloid leukemia
    • Freund, M., Giller, S., Hinrichs, F., Baars, A., Meran, J., Korfer, A., Link, H., and Poliwoda, H. (1991). Five-day 4′-(9-acridinylamino)methanesulphon-m-anisidide and intermediate-dose cytosine arabinoside in high-risk relapsing or refractory acute myeloid leukemia. J. Cancer Res. Clin. Oncol. 117, 489-492.
    • (1991) J. Cancer Res. Clin. Oncol. , vol.117 , pp. 489-492
    • Freund, M.1    Giller, S.2    Hinrichs, F.3    Baars, A.4    Meran, J.5    Korfer, A.6    Link, H.7    Poliwoda, H.8
  • 24
    • 0027488886 scopus 로고
    • The immune system response during development and progression of carcinogen-induced rat mammary tumors: Prevention of tumor growth and restoration of immune system responsiveness by thymopentin
    • Gallo, F., Morale, M. C., Sambataro, D., Farinella, Z., Scapagnini, U., and Marchetti, B. (1993). The immune system response during development and progression of carcinogen-induced rat mammary tumors: Prevention of tumor growth and restoration of immune system responsiveness by thymopentin. Breast Cancer Res. Treat. 27, 221-237.
    • (1993) Breast Cancer Res. Treat. , vol.27 , pp. 221-237
    • Gallo, F.1    Morale, M.C.2    Sambataro, D.3    Farinella, Z.4    Scapagnini, U.5    Marchetti, B.6
  • 25
    • 0018761565 scopus 로고
    • Statistical issues in interpretation of chronic bioassay tests for carcinogenicity
    • Gart, J. J., Chu, K. C., and Tarone, R. E. (1979). Statistical issues in interpretation of chronic bioassay tests for carcinogenicity. J. Natl. Cancer Inst. 62, 957-974.
    • (1979) J. Natl. Cancer Inst. , vol.62 , pp. 957-974
    • Gart, J.J.1    Chu, K.C.2    Tarone, R.E.3
  • 26
    • 0027463052 scopus 로고
    • Comparison of target organs of carcinogenicity for mutagenic and non-mutagenic chemicals
    • Gold, L. S., Slone, T. H., Stern, B. R., and Bernstein, L. (1993). Comparison of target organs of carcinogenicity for mutagenic and non-mutagenic chemicals. Mutat. Res. 286, 75-100.
    • (1993) Mutat. Res. , vol.286 , pp. 75-100
    • Gold, L.S.1    Slone, T.H.2    Stern, B.R.3    Bernstein, L.4
  • 27
    • 0028138989 scopus 로고
    • Induction of small intestinal adenocarcinomas in Wistar rats administered amsacrine
    • Gough, A., Courtney, C., and Graziano, M. (1994). Induction of small intestinal adenocarcinomas in Wistar rats administered amsacrine. Exp. Toxicol. Pathol. 46, 275-281.
    • (1994) Exp. Toxicol. Pathol. , vol.46 , pp. 275-281
    • Gough, A.1    Courtney, C.2    Graziano, M.3
  • 28
    • 0027156736 scopus 로고
    • Correlations between chemically related site-specific carcinogenic effects in long-term studies in rats and mice
    • Haseman, J. K., and Lockhart, A.-M. (1993). Correlations between chemically related site-specific carcinogenic effects in long-term studies in rats and mice. Environ. Health Perspect. 101, 50-54.
    • (1993) Environ. Health Perspect. , vol.101 , pp. 50-54
    • Haseman, J.K.1    Lockhart, A.-M.2
  • 29
    • 0019259193 scopus 로고
    • Preclinical toxicologic evaluation of 4′-(9-acridinylamino)methanesulfon-m-anisidide (AMSA) in mice, dogs, and monkeys
    • Henry, M. C., Port, C. D., and Levine, B. S. (1980). Preclinical toxicologic evaluation of 4′-(9-acridinylamino)methanesulfon-m-anisidide (AMSA) in mice, dogs, and monkeys. Cancer Treat. Rep. 64, 855-860.
    • (1980) Cancer Treat. Rep. , vol.64 , pp. 855-860
    • Henry, M.C.1    Port, C.D.2    Levine, B.S.3
  • 30
    • 0021613807 scopus 로고
    • High-dose cytosine arabinoside and m-AMSA is effective therapy in relapsed acute nonlymphocytic leukemia
    • Hines, J. D., Oken, M. M., Mazza, J. J., Keller, A. M., Streeter, R. R., and Glick, J. H. (1984). High-dose cytosine arabinoside and m-AMSA is effective therapy in relapsed acute nonlymphocytic leukemia. J. Clin. Oncol. 2, 545-549.
    • (1984) J. Clin. Oncol. , vol.2 , pp. 545-549
    • Hines, J.D.1    Oken, M.M.2    Mazza, J.J.3    Keller, A.M.4    Streeter, R.R.5    Glick, J.H.6
  • 31
    • 0026555984 scopus 로고
    • Micronucleus induction by camptothecin and amsacrine in bone marrow of male and female CD-1 mice
    • Holmstrom, M., and Winters, V. (1992). Micronucleus induction by camptothecin and amsacrine in bone marrow of male and female CD-1 mice. Mutagenesis 7, 189-193.
    • (1992) Mutagenesis , vol.7 , pp. 189-193
    • Holmstrom, M.1    Winters, V.2
  • 32
    • 0026705622 scopus 로고
    • Mutagenic activities of azido analogues of amsacrine and other 9-anilinoacridines in Salmonella typhimurium and their enhancement by photoirradiation
    • Iwamoto, Y., Ferguson, L. R., Pogai, H. B., Uzuhashi, T., Kurita, A., Yangihara, Y., and Denny, W. A. (1992). Mutagenic activities of azido analogues of amsacrine and other 9-anilinoacridines in Salmonella typhimurium and their enhancement by photoirradiation. Mutat. Res. 280, 233-244.
    • (1992) Mutat. Res. , vol.280 , pp. 233-244
    • Iwamoto, Y.1    Ferguson, L.R.2    Pogai, H.B.3    Uzuhashi, T.4    Kurita, A.5    Yangihara, Y.6    Denny, W.A.7
  • 33
    • 0025741218 scopus 로고
    • New drugs in the treatment of acute and chronic leukemia with some emphasis on m-AMSA
    • Jehn, U., and Heinemann, V. (1991). New drugs in the treatment of acute and chronic leukemia with some emphasis on m-AMSA. Anticancer Res. 11, 705-712.
    • (1991) Anticancer Res. , vol.11 , pp. 705-712
    • Jehn, U.1    Heinemann, V.2
  • 34
    • 0023920752 scopus 로고
    • Quantifying the carcinogenicity of antineoplastic drugs
    • Kaldor, J. M., Day, N. E., and Hemminki, K. (1988). Quantifying the carcinogenicity of antineoplastic drugs. Eur. J. Cancer Clin. Oncol. 24, 703-711.
    • (1988) Eur. J. Cancer Clin. Oncol. , vol.24 , pp. 703-711
    • Kaldor, J.M.1    Day, N.E.2    Hemminki, K.3
  • 35
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • Kaplan, E. L., and Meier, P. (1958). Nonparametric estimation from incomplete observations. J. Am. Stat. Assoc. 53, 457-481.
    • (1958) J. Am. Stat. Assoc. , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 37
    • 0019944571 scopus 로고
    • Evaluation of AMSA in previously treated patients with acute leukemia: Results of therapy in 109 adults
    • Legha, S. S., Keating, M. J., McCredie, K. B., Bodey, G. P., and Freireich, E. J. (1982). Evaluation of AMSA in previously treated patients with acute leukemia: Results of therapy in 109 adults. Blood 60, 484-490.
    • (1982) Blood , vol.60 , pp. 484-490
    • Legha, S.S.1    Keating, M.J.2    McCredie, K.B.3    Bodey, G.P.4    Freireich, E.J.5
  • 38
    • 0023006294 scopus 로고
    • Induction of sister chromatid exchanges by inhibitors of topoisomerases
    • Lim, M., Liu, M. F., Jacobson-Kram, D., and Williams, J. R. (1986). Induction of sister chromatid exchanges by inhibitors of topoisomerases. Cell Biol. Toxicol. 2, 485-494.
    • (1986) Cell Biol. Toxicol. , vol.2 , pp. 485-494
    • Lim, M.1    Liu, M.F.2    Jacobson-Kram, D.3    Williams, J.R.4
  • 39
    • 0024316466 scopus 로고
    • DNA topoisomerase poisons as antitumor drugs
    • Liu, L. F. (1989). DNA topoisomerase poisons as antitumor drugs. Annu. Rev. Biochem. 58, 351-375.
    • (1989) Annu. Rev. Biochem. , vol.58 , pp. 351-375
    • Liu, L.F.1
  • 40
    • 0025943536 scopus 로고
    • Carcinogenic properties of pharmaceutical agents evaluated in the IARC monographs programme
    • Marselos, M., and Vainio, H. (1991). Carcinogenic properties of pharmaceutical agents evaluated in the IARC Monographs programme. Carcinogenesis 12, 1751-1766.
    • (1991) Carcinogenesis , vol.12 , pp. 1751-1766
    • Marselos, M.1    Vainio, H.2
  • 41
    • 0027049136 scopus 로고
    • AMSA combination chemotherapy in patients with acute myelogenous leukemia unsuitable for standard antileukemic treatment
    • Maschmeyer, G., Willborn, K., and Heit, W. (1992). AMSA combination chemotherapy in patients with acute myelogenous leukemia unsuitable for standard antileukemic treatment. Leuk. Lymphoma 8, 365-369.
    • (1992) Leuk. Lymphoma , vol.8 , pp. 365-369
    • Maschmeyer, G.1    Willborn, K.2    Heit, W.3
  • 42
    • 0028310293 scopus 로고
    • Characterization of a chemically induced tumor model and the effects of natural killer cell depletion by antiasialo GM-1
    • Mather, G. G., Talcott, P. A., and Exon, J. H. (1994). Characterization of a chemically induced tumor model and the effects of natural killer cell depletion by antiasialo GM-1. Immunobiology 190, 333-345.
    • (1994) Immunobiology , vol.190 , pp. 333-345
    • Mather, G.G.1    Talcott, P.A.2    Exon, J.H.3
  • 43
    • 0026360043 scopus 로고
    • Successful reinduction therapy with amsacrine and cyclocytidine in acute nonlymphoblastic leukemia in children. A report from the childrens cancer study group
    • Miller, L. P., Pyesmany, A. F., Wolff, L. J., Rogers, P. C., Siegel, S. E., Wells, R. J., Buckley, J. D., and Hammond, G. D. (1991). Successful reinduction therapy with amsacrine and cyclocytidine in acute nonlymphoblastic leukemia in children. A report from the Childrens Cancer Study Group. Cancer 67, 2235-2240.
    • (1991) Cancer , vol.67 , pp. 2235-2240
    • Miller, L.P.1    Pyesmany, A.F.2    Wolff, L.J.3    Rogers, P.C.4    Siegel, S.E.5    Wells, R.J.6    Buckley, J.D.7    Hammond, G.D.8
  • 44
    • 0022514876 scopus 로고
    • Isolation of intercalator-dependent protein-linked DNA strand cleavage activity from cell nuclei and identification as topoisomerase II
    • Minford, J., Pommier, Y., Filipski, J., Kohn, K. W., Kerrigan, D., Mattern, M., Michaels, S., Schwartz, R., and Zwelling, L. A. (1986). Isolation of intercalator-dependent protein-linked DNA strand cleavage activity from cell nuclei and identification as topoisomerase II. Biochemistry 25, 9-16.
    • (1986) Biochemistry , vol.25 , pp. 9-16
    • Minford, J.1    Pommier, Y.2    Filipski, J.3    Kohn, K.W.4    Kerrigan, D.5    Mattern, M.6    Michaels, S.7    Schwartz, R.8    Zwelling, L.A.9
  • 45
    • 0029156694 scopus 로고
    • Expression of exposure in negative carcinogenicity studies: Dose/body weight, dose/body surface area, or plasma concentrations?
    • Monro, A., and Mordenti, J. (1995). Expression of exposure in negative carcinogenicity studies: Dose/body weight, dose/body surface area, or plasma concentrations? Toxicologic Pathol. 23, 187-198.
    • (1995) Toxicologic Pathol. , vol.23 , pp. 187-198
    • Monro, A.1    Mordenti, J.2
  • 46
    • 0003668668 scopus 로고
    • CAS 952-23-8. Carcinogenesis Technical Report Series 5, DHEW Publication (NIH) 77-805
    • National Cancer Institute (1977). Bioassay of Proflavine for Possible Carcinogenicity. CAS 952-23-8. Carcinogenesis Technical Report Series 5, DHEW Publication (NIH) 77-805.
    • (1977) Bioassay of Proflavine for Possible Carcinogenicity
  • 47
    • 0021333644 scopus 로고
    • Mechanism of antitumor drug action: Poisoning of mammalian DNA topoisomerase II on DNA by 4′-(9-acridinylamino)-methanesulfon-m-anisidide
    • Nelson, E. M., Tewey, K. M., and Liu, L. F. (1984). Mechanism of antitumor drug action: Poisoning of mammalian DNA topoisomerase II on DNA by 4′-(9-acridinylamino)-methanesulfon-m-anisidide. Proc. Natl. Acad. Sci. USA 81, 1361-1365.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 1361-1365
    • Nelson, E.M.1    Tewey, K.M.2    Liu, L.F.3
  • 48
    • 0017185669 scopus 로고
    • Pulmonary carcinogenesis by derivatives of polynuclear aromatic alkylating agents
    • Peck, R. M., Tan, T. K., and Peck, E. B. (1976). Pulmonary carcinogenesis by derivatives of polynuclear aromatic alkylating agents. Cancer Res. 36, 2423-2427.
    • (1976) Cancer Res. , vol.36 , pp. 2423-2427
    • Peck, R.M.1    Tan, T.K.2    Peck, E.B.3
  • 49
    • 85033066248 scopus 로고    scopus 로고
    • Subchronic intravenous toxicity of the antineoplastic drug, amsacrine, in male Wistar rats
    • Pegg, D. G., Watkins, J. R., Graziano, M. J., and McKenna, M. J. (1996). Subchronic intravenous toxicity of the antineoplastic drug, amsacrine, in male Wistar rats. Fund. Appl. Toxicol. 32, 45-52.
    • (1996) Fund. Appl. Toxicol. , vol.32 , pp. 45-52
    • Pegg, D.G.1    Watkins, J.R.2    Graziano, M.J.3    McKenna, M.J.4
  • 51
    • 0023493551 scopus 로고
    • Role of DNA intercalation in the inhibition of purified mouse leukemia (L1210) DNA topoisomerase II by 9-aminoacridines
    • Pommier, Y., Covey, J., Kerrigan, D., Mattes, W., Markovits, J., and Kohn, K. W. (1987). Role of DNA intercalation in the inhibition of purified mouse leukemia (L1210) DNA topoisomerase II by 9-aminoacridines. Biochem. Pharmacol. 36, 3477-3486.
    • (1987) Biochem. Pharmacol. , vol.36 , pp. 3477-3486
    • Pommier, Y.1    Covey, J.2    Kerrigan, D.3    Mattes, W.4    Markovits, J.5    Kohn, K.W.6
  • 52
    • 0021153767 scopus 로고
    • Formation and rejoining of deoxyribonucleic acid double-strand breaks induced in isolated cell nuclei by antineoplastic intercalating agents
    • Pommier, Y., Schwartz, R. E., Kohn, K. W., and Zwelling, L. A. (1984). Formation and rejoining of deoxyribonucleic acid double-strand breaks induced in isolated cell nuclei by antineoplastic intercalating agents. Biochemistry 23, 3194-3201.
    • (1984) Biochemistry , vol.23 , pp. 3194-3201
    • Pommier, Y.1    Schwartz, R.E.2    Kohn, K.W.3    Zwelling, L.A.4
  • 53
    • 0021631110 scopus 로고
    • Carcinogenicity of antineoplastic agents in man
    • Rieche, K. (1984). Carcinogenicity of antineoplastic agents in man. Cancer Treat. Rev. 11, 39-67.
    • (1984) Cancer Treat. Rev. , vol.11 , pp. 39-67
    • Rieche, K.1
  • 54
    • 0022656381 scopus 로고
    • DNA damage by antitumor acridines mediated by mammalian DNA topoisomerase II
    • Rowe, T. C., Chen, G. L., Hsiang, Y.-H., and Liu, L. F. (1986). DNA damage by antitumor acridines mediated by mammalian DNA topoisomerase II. Cancer Res. 46, 2021-2026.
    • (1986) Cancer Res. , vol.46 , pp. 2021-2026
    • Rowe, T.C.1    Chen, G.L.2    Hsiang, Y.-H.3    Liu, L.F.4
  • 55
    • 0026510803 scopus 로고
    • Immunosuppression and cancer: The ciclosporin case
    • Ryffel, B., Mihatsch, M. J., and Fisher, G. L. (1992). Immunosuppression and cancer: The ciclosporin case. Drug Chem. Toxicol. 15, 95-115.
    • (1992) Drug Chem. Toxicol. , vol.15 , pp. 95-115
    • Ryffel, B.1    Mihatsch, M.J.2    Fisher, G.L.3
  • 56
    • 0026665545 scopus 로고
    • Human immunodeficiency virus as a risk factor in miscellaneous cancers
    • Spina, M., and Tirelli, U. (1992). Human immunodeficiency virus as a risk factor in miscellaneous cancers. Curr. Opin. Oncol. 4, 907-910.
    • (1992) Curr. Opin. Oncol. , vol.4 , pp. 907-910
    • Spina, M.1    Tirelli, U.2
  • 57
    • 0025214172 scopus 로고
    • Double intensification with amsacrine/high dose ara-c and high dose chemotherapy with autologous bone marrow transplantation produces durable remissions in acute myelogenous leukemia
    • Spinolo, J. A., Dicke, K. A., Horwitz, L. J., Jagannath, S., Zander, A. R., Auber, M. L., and Spitzer, G. (1990). Double intensification with amsacrine/high dose ara-c and high dose chemotherapy with autologous bone marrow transplantation produces durable remissions in acute myelogenous leukemia. Bone Marrow Transplant 5, 111-118.
    • (1990) Bone Marrow Transplant , vol.5 , pp. 111-118
    • Spinolo, J.A.1    Dicke, K.A.2    Horwitz, L.J.3    Jagannath, S.4    Zander, A.R.5    Auber, M.L.6    Spitzer, G.7
  • 58
    • 0016759979 scopus 로고
    • Tests for trend in life table analysis
    • Tarone, R. E. (1975). Tests for trend in life table analysis. Biometrika 62, 679-682.
    • (1975) Biometrika , vol.62 , pp. 679-682
    • Tarone, R.E.1
  • 59
    • 0017336302 scopus 로고
    • On distribution-free tests for equality of survival distributions
    • Tarone, R. E., and Ware, J. (1977). On distribution-free tests for equality of survival distributions. Biometrika 64, 156-160.
    • (1977) Biometrika , vol.64 , pp. 156-160
    • Tarone, R.E.1    Ware, J.2
  • 60
    • 77957176959 scopus 로고
    • Spontaneous neoplasms in control Wistar rats
    • Walsh, K. M., and Poteracki, J. (1994). Spontaneous neoplasms in control Wistar rats. Fund. Appl. Toxicol. 22, 65-72.
    • (1994) Fund. Appl. Toxicol. , vol.22 , pp. 65-72
    • Walsh, K.M.1    Poteracki, J.2
  • 61
    • 0023787257 scopus 로고
    • Intermediate and high dose Ara-C and m-AMSA for remission induction and consolidation treatment of patients with acute myeloid leukemia: An EORTC leukemia cooperative group phase II study
    • Willemze, R., Jager, U., Jehn, U., Stryckmans, P., Bury, J., Suciu, S., Solbu, G., Zittoun, R., Burghouts, J., Lowenberg, B., Abels, J., and Cauchie, CH. (1988). Intermediate and high dose Ara-C and m-AMSA for remission induction and consolidation treatment of patients with acute myeloid leukemia: An EORTC Leukemia Cooperative Group phase II study. Eur. J. Cancer Clin. Oncol. 24, 1721-1725.
    • (1988) Eur. J. Cancer Clin. Oncol. , vol.24 , pp. 1721-1725
    • Willemze, R.1    Jager, U.2    Jehn, U.3    Stryckmans, P.4    Bury, J.5    Suciu, S.6    Solbu, G.7    Zittoun, R.8    Burghouts, J.9    Lowenberg, B.10    Abels, J.11    Cauchie, C.H.12
  • 63
    • 0019867969 scopus 로고
    • Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4′-(9-acridinylamino)methanesulfon-m-anisidide and adriamycin
    • Zwelling, L. A., Michaels, S., Erickson, L. C., Ungerleider, R. S., Nichols, M., and Kohn, K. W. (1981). Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4′-(9-acridinylamino)methanesulfon-m-anisidide and adriamycin. Biochemistry 20, 6553-6563.
    • (1981) Biochemistry , vol.20 , pp. 6553-6563
    • Zwelling, L.A.1    Michaels, S.2    Erickson, L.C.3    Ungerleider, R.S.4    Nichols, M.5    Kohn, K.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.