-
1
-
-
0025009192
-
Chemical carcinogenesis: Too many rodent carcinogens
-
Ames, B. N., and Gold, L. S. (1990). Chemical carcinogenesis: Too many rodent carcinogens. Proc. Natl. Acad. Sci. USA 87, 7772-7776.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 7772-7776
-
-
Ames, B.N.1
Gold, L.S.2
-
2
-
-
0024507201
-
The production of chromosomal alterations in human lymphocytes by drugs known to interfere with the activity of DNA topoisomerase II. I. m-Amsa
-
Andersson, H. C., and Kihlman, B. A. (1989). The production of chromosomal alterations in human lymphocytes by drugs known to interfere with the activity of DNA topoisomerase II. I. m-Amsa. Carcinogenesis 10, 123-130.
-
(1989)
Carcinogenesis
, vol.10
, pp. 123-130
-
-
Andersson, H.C.1
Kihlman, B.A.2
-
3
-
-
0024955726
-
A special role for amsacrine in the treatment of acute leukemia
-
Arlin, Z. A. (1989). A special role for amsacrine in the treatment of acute leukemia. Cancer Invest. 7, 607-609.
-
(1989)
Cancer Invest.
, vol.7
, pp. 607-609
-
-
Arlin, Z.A.1
-
4
-
-
0023759254
-
Amsacrine with high-dose cytarabine is highly effective therapy for refractory and relapsed acute lymphoblastic leukemia in adults
-
Arlin, Z. A., Feldman, E., Kempin, S., Ahmed, T., Mittelman, A., Savona, S., Ascensao, J., Baskind, P., Sullivan, P., Fuhr, H. G., and Mertelsmann, R. (1988). Amsacrine with high-dose cytarabine is highly effective therapy for refractory and relapsed acute lymphoblastic leukemia in adults. Blood 72, 433-435.
-
(1988)
Blood
, vol.72
, pp. 433-435
-
-
Arlin, Z.A.1
Feldman, E.2
Kempin, S.3
Ahmed, T.4
Mittelman, A.5
Savona, S.6
Ascensao, J.7
Baskind, P.8
Sullivan, P.9
Fuhr, H.G.10
Mertelsmann, R.11
-
5
-
-
0025938458
-
Amsacrine is safe and effective therapy for patients with myocardial dysfunction and acute leukemia
-
Arlin, Z. A., Feldman, E. J., Mittelman, A., Ahmed, T., Puccio, C., Chun, H. G., Cook, P., Baskind, P., Marboe, C., and Mehta, R. (1991). Amsacrine is safe and effective therapy for patients with myocardial dysfunction and acute leukemia. Cancer 68, 1198-1200.
-
(1991)
Cancer
, vol.68
, pp. 1198-1200
-
-
Arlin, Z.A.1
Feldman, E.J.2
Mittelman, A.3
Ahmed, T.4
Puccio, C.5
Chun, H.G.6
Cook, P.7
Baskind, P.8
Marboe, C.9
Mehta, R.10
-
6
-
-
0018966583
-
Phase I and II trial of 4′-(9-acridinylamino)methanesulfon-m-anisidide in patients with acute leukemia
-
Arlin, Z. A., Sklaroff, R. B., Gee, T. S., Kempin, S. J., Howard, J., Clarkson, B. D., and Young, C. W. (1980). Phase I and II trial of 4′-(9-acridinylamino)methanesulfon-m-anisidide in patients with acute leukemia. Cancer Res. 40, 3304-3306.
-
(1980)
Cancer Res.
, vol.40
, pp. 3304-3306
-
-
Arlin, Z.A.1
Sklaroff, R.B.2
Gee, T.S.3
Kempin, S.J.4
Howard, J.5
Clarkson, B.D.6
Young, C.W.7
-
9
-
-
0023856614
-
Chemical structure, salmonella mutagenicity and extent of carcinogenicity as indicators of genotoxic carcinogenesis among 222 chemicals tested in rodents by the U.S. NCI/ NTP
-
Ashby, J., and Tennant, R. W. (1988). Chemical structure, Salmonella mutagenicity and extent of carcinogenicity as indicators of genotoxic carcinogenesis among 222 chemicals tested in rodents by the U.S. NCI/ NTP. Mutat. Res. 204, 17-115.
-
(1988)
Mutat. Res.
, vol.204
, pp. 17-115
-
-
Ashby, J.1
Tennant, R.W.2
-
10
-
-
0025049435
-
Genotoxicity of inhibitors of DNA topoisomerases I (camptothecin) and II (m-AMSA) in vivo and in vitro
-
Backer, L. C., Allen, J. W., Harrington-Brock, K., Campbell, J. A., DeMarini, D. M., Doerr, C. L., Howard, D. R., Kligerman, A. D., and Moore, M. M. (1990). Genotoxicity of inhibitors of DNA topoisomerases I (camptothecin) and II (m-AMSA) in vivo and in vitro. Mutagenesis 5, 541-547.
-
(1990)
Mutagenesis
, vol.5
, pp. 541-547
-
-
Backer, L.C.1
Allen, J.W.2
Harrington-Brock, K.3
Campbell, J.A.4
DeMarini, D.M.5
Doerr, C.L.6
Howard, D.R.7
Kligerman, A.D.8
Moore, M.M.9
-
11
-
-
0028308415
-
Frequency of spontaneous tumours in Wistar rats in 2-year studies
-
Bombard, E., and Rinke, M. (1994). Frequency of spontaneous tumours in Wistar rats in 2-year studies. Exp. Toxicol. Pathol. 46, 17-29.
-
(1994)
Exp. Toxicol. Pathol.
, vol.46
, pp. 17-29
-
-
Bombard, E.1
Rinke, M.2
-
12
-
-
0025820646
-
A critique of the use of the maximum tolerated dose in bioassays to assess cancer risks from chemicals
-
Carr, C. J., and Kolbye, A. C. (1991). A critique of the use of the maximum tolerated dose in bioassays to assess cancer risks from chemicals. Regul. Toxicol. Pharmacol. 14, 78-87.
-
(1991)
Regul. Toxicol. Pharmacol.
, vol.14
, pp. 78-87
-
-
Carr, C.J.1
Kolbye, A.C.2
-
13
-
-
0026344785
-
An appreciation of the maximum tolerated dose: An inadequately precise decision point in designing a carcinogenesis bioassay?
-
Clayson, D. B., Iverson, F., and Mueller, R. (1991). An appreciation of the maximum tolerated dose: An inadequately precise decision point in designing a carcinogenesis bioassay? Teratogen. Carcinog. Mutagen. 11, 279-296.
-
(1991)
Teratogen. Carcinog. Mutagen.
, vol.11
, pp. 279-296
-
-
Clayson, D.B.1
Iverson, F.2
Mueller, R.3
-
14
-
-
0026625103
-
Granular basal cell tumor in a Wistar rat
-
Courtney, C. L., Hawkins, K. L., and Graziano, M. J. (1992a). Granular basal cell tumor in a Wistar rat. Toxicol. Pathol. 20, 122-124.
-
(1992)
Toxicol. Pathol.
, vol.20
, pp. 122-124
-
-
Courtney, C.L.1
Hawkins, K.L.2
Graziano, M.J.3
-
15
-
-
0026450056
-
Immunohistochemical and ultrastructural characterization of granular cell tumors of the female reproductive tract in two aged Wistar rats
-
Courtney, C. L., Hawkins, K. L., Meierhenry, E. F., and Graziano, M. J. (1992b). Immunohistochemical and ultrastructural characterization of granular cell tumors of the female reproductive tract in two aged Wistar rats. Vet. Pathol. 29, 86-89.
-
(1992)
Vet. Pathol.
, vol.29
, pp. 86-89
-
-
Courtney, C.L.1
Hawkins, K.L.2
Meierhenry, E.F.3
Graziano, M.J.4
-
16
-
-
0023883103
-
Topoisomerase II-mediated DNA damage produced by 4′-(9-acridinylamino)-methanesulfon-m-anisidide and related acridines in L1210 cells and isolated nuclei: Relation to cytotoxicity
-
Covey, J. M., Kohn, K. W., Kerrigan, D., Tilchen, E. J., and Pommier, Y. (1988). Topoisomerase II-mediated DNA damage produced by 4′-(9-acridinylamino)-methanesulfon-m-anisidide and related acridines in L1210 cells and isolated nuclei: Relation to cytotoxicity. Cancer Res. 48, 860-865.
-
(1988)
Cancer Res.
, vol.48
, pp. 860-865
-
-
Covey, J.M.1
Kohn, K.W.2
Kerrigan, D.3
Tilchen, E.J.4
Pommier, Y.5
-
17
-
-
0027292407
-
DNA topoisomerase I and II as targets for rational design of new anticancer drugs
-
Cummings, J., and Smyth, J. F. (1993). DNA topoisomerase I and II as targets for rational design of new anticancer drugs. Ann. Oncol. 4, 533-543.
-
(1993)
Ann. Oncol.
, vol.4
, pp. 533-543
-
-
Cummings, J.1
Smyth, J.F.2
-
18
-
-
0017592982
-
The pharmacologic disposition of 4′-(9-acridinylamino)methanesulfon-m-anisidide in mice and rats
-
Cysyk, R. L., Shoemaker, D., and Adamson, R. H. (1977). The pharmacologic disposition of 4′-(9-acridinylamino)methanesulfon-m-anisidide in mice and rats. Drug Metab. Disp. 5, 579-590.
-
(1977)
Drug Metab. Disp.
, vol.5
, pp. 579-590
-
-
Cysyk, R.L.1
Shoemaker, D.2
Adamson, R.H.3
-
19
-
-
0025264490
-
Intermediate-dose cytosine arabinoside and amsacrine
-
Dekker, A. W., Nieuwenhuis, H. K., and Verdonck, L. F. (1990). Intermediate-dose cytosine arabinoside and amsacrine. Cancer 65, 1891-1894.
-
(1990)
Cancer
, vol.65
, pp. 1891-1894
-
-
Dekker, A.W.1
Nieuwenhuis, H.K.2
Verdonck, L.F.3
-
20
-
-
0023403294
-
Mutagenicity of m-AMSA and o-AMSA in mammalian cells due to clastogenic mechanism: Possible role of topoisomerase
-
DeMarini, D. M., Doerr, C. L., Meyer, M. K., Brock, K. H., Hozier, J., and Moore, R. M. (1987). Mutagenicity of m-AMSA and o-AMSA in mammalian cells due to clastogenic mechanism: Possible role of topoisomerase. Mutagenesis 2, 349-355.
-
(1987)
Mutagenesis
, vol.2
, pp. 349-355
-
-
DeMarini, D.M.1
Doerr, C.L.2
Meyer, M.K.3
Brock, K.H.4
Hozier, J.5
Moore, R.M.6
-
21
-
-
0025768698
-
The genetic toxicology of acridines
-
Ferguson, L. R., and Denny, W. A. (1991). The genetic toxicology of acridines. Mutat. Res. 258, 123-160.
-
(1991)
Mutat. Res.
, vol.258
, pp. 123-160
-
-
Ferguson, L.R.1
Denny, W.A.2
-
22
-
-
0013909023
-
Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey, and man
-
Freireich, E. J., Gehan, E. A., Rall, D. P., Schmidt, L. H., and Skipper, H. E. (1966). Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey, and man. Cancer Chemother. Rep. 50, 219-244.
-
(1966)
Cancer Chemother. Rep.
, vol.50
, pp. 219-244
-
-
Freireich, E.J.1
Gehan, E.A.2
Rall, D.P.3
Schmidt, L.H.4
Skipper, H.E.5
-
23
-
-
0025787478
-
Five-day 4′-(9-acridinylamino)methanesulphon-m-anisidide and intermediate-dose cytosine arabinoside in high-risk relapsing or refractory acute myeloid leukemia
-
Freund, M., Giller, S., Hinrichs, F., Baars, A., Meran, J., Korfer, A., Link, H., and Poliwoda, H. (1991). Five-day 4′-(9-acridinylamino)methanesulphon-m-anisidide and intermediate-dose cytosine arabinoside in high-risk relapsing or refractory acute myeloid leukemia. J. Cancer Res. Clin. Oncol. 117, 489-492.
-
(1991)
J. Cancer Res. Clin. Oncol.
, vol.117
, pp. 489-492
-
-
Freund, M.1
Giller, S.2
Hinrichs, F.3
Baars, A.4
Meran, J.5
Korfer, A.6
Link, H.7
Poliwoda, H.8
-
24
-
-
0027488886
-
The immune system response during development and progression of carcinogen-induced rat mammary tumors: Prevention of tumor growth and restoration of immune system responsiveness by thymopentin
-
Gallo, F., Morale, M. C., Sambataro, D., Farinella, Z., Scapagnini, U., and Marchetti, B. (1993). The immune system response during development and progression of carcinogen-induced rat mammary tumors: Prevention of tumor growth and restoration of immune system responsiveness by thymopentin. Breast Cancer Res. Treat. 27, 221-237.
-
(1993)
Breast Cancer Res. Treat.
, vol.27
, pp. 221-237
-
-
Gallo, F.1
Morale, M.C.2
Sambataro, D.3
Farinella, Z.4
Scapagnini, U.5
Marchetti, B.6
-
25
-
-
0018761565
-
Statistical issues in interpretation of chronic bioassay tests for carcinogenicity
-
Gart, J. J., Chu, K. C., and Tarone, R. E. (1979). Statistical issues in interpretation of chronic bioassay tests for carcinogenicity. J. Natl. Cancer Inst. 62, 957-974.
-
(1979)
J. Natl. Cancer Inst.
, vol.62
, pp. 957-974
-
-
Gart, J.J.1
Chu, K.C.2
Tarone, R.E.3
-
26
-
-
0027463052
-
Comparison of target organs of carcinogenicity for mutagenic and non-mutagenic chemicals
-
Gold, L. S., Slone, T. H., Stern, B. R., and Bernstein, L. (1993). Comparison of target organs of carcinogenicity for mutagenic and non-mutagenic chemicals. Mutat. Res. 286, 75-100.
-
(1993)
Mutat. Res.
, vol.286
, pp. 75-100
-
-
Gold, L.S.1
Slone, T.H.2
Stern, B.R.3
Bernstein, L.4
-
27
-
-
0028138989
-
Induction of small intestinal adenocarcinomas in Wistar rats administered amsacrine
-
Gough, A., Courtney, C., and Graziano, M. (1994). Induction of small intestinal adenocarcinomas in Wistar rats administered amsacrine. Exp. Toxicol. Pathol. 46, 275-281.
-
(1994)
Exp. Toxicol. Pathol.
, vol.46
, pp. 275-281
-
-
Gough, A.1
Courtney, C.2
Graziano, M.3
-
28
-
-
0027156736
-
Correlations between chemically related site-specific carcinogenic effects in long-term studies in rats and mice
-
Haseman, J. K., and Lockhart, A.-M. (1993). Correlations between chemically related site-specific carcinogenic effects in long-term studies in rats and mice. Environ. Health Perspect. 101, 50-54.
-
(1993)
Environ. Health Perspect.
, vol.101
, pp. 50-54
-
-
Haseman, J.K.1
Lockhart, A.-M.2
-
29
-
-
0019259193
-
Preclinical toxicologic evaluation of 4′-(9-acridinylamino)methanesulfon-m-anisidide (AMSA) in mice, dogs, and monkeys
-
Henry, M. C., Port, C. D., and Levine, B. S. (1980). Preclinical toxicologic evaluation of 4′-(9-acridinylamino)methanesulfon-m-anisidide (AMSA) in mice, dogs, and monkeys. Cancer Treat. Rep. 64, 855-860.
-
(1980)
Cancer Treat. Rep.
, vol.64
, pp. 855-860
-
-
Henry, M.C.1
Port, C.D.2
Levine, B.S.3
-
30
-
-
0021613807
-
High-dose cytosine arabinoside and m-AMSA is effective therapy in relapsed acute nonlymphocytic leukemia
-
Hines, J. D., Oken, M. M., Mazza, J. J., Keller, A. M., Streeter, R. R., and Glick, J. H. (1984). High-dose cytosine arabinoside and m-AMSA is effective therapy in relapsed acute nonlymphocytic leukemia. J. Clin. Oncol. 2, 545-549.
-
(1984)
J. Clin. Oncol.
, vol.2
, pp. 545-549
-
-
Hines, J.D.1
Oken, M.M.2
Mazza, J.J.3
Keller, A.M.4
Streeter, R.R.5
Glick, J.H.6
-
31
-
-
0026555984
-
Micronucleus induction by camptothecin and amsacrine in bone marrow of male and female CD-1 mice
-
Holmstrom, M., and Winters, V. (1992). Micronucleus induction by camptothecin and amsacrine in bone marrow of male and female CD-1 mice. Mutagenesis 7, 189-193.
-
(1992)
Mutagenesis
, vol.7
, pp. 189-193
-
-
Holmstrom, M.1
Winters, V.2
-
32
-
-
0026705622
-
Mutagenic activities of azido analogues of amsacrine and other 9-anilinoacridines in Salmonella typhimurium and their enhancement by photoirradiation
-
Iwamoto, Y., Ferguson, L. R., Pogai, H. B., Uzuhashi, T., Kurita, A., Yangihara, Y., and Denny, W. A. (1992). Mutagenic activities of azido analogues of amsacrine and other 9-anilinoacridines in Salmonella typhimurium and their enhancement by photoirradiation. Mutat. Res. 280, 233-244.
-
(1992)
Mutat. Res.
, vol.280
, pp. 233-244
-
-
Iwamoto, Y.1
Ferguson, L.R.2
Pogai, H.B.3
Uzuhashi, T.4
Kurita, A.5
Yangihara, Y.6
Denny, W.A.7
-
33
-
-
0025741218
-
New drugs in the treatment of acute and chronic leukemia with some emphasis on m-AMSA
-
Jehn, U., and Heinemann, V. (1991). New drugs in the treatment of acute and chronic leukemia with some emphasis on m-AMSA. Anticancer Res. 11, 705-712.
-
(1991)
Anticancer Res.
, vol.11
, pp. 705-712
-
-
Jehn, U.1
Heinemann, V.2
-
34
-
-
0023920752
-
Quantifying the carcinogenicity of antineoplastic drugs
-
Kaldor, J. M., Day, N. E., and Hemminki, K. (1988). Quantifying the carcinogenicity of antineoplastic drugs. Eur. J. Cancer Clin. Oncol. 24, 703-711.
-
(1988)
Eur. J. Cancer Clin. Oncol.
, vol.24
, pp. 703-711
-
-
Kaldor, J.M.1
Day, N.E.2
Hemminki, K.3
-
35
-
-
33845382806
-
Nonparametric estimation from incomplete observations
-
Kaplan, E. L., and Meier, P. (1958). Nonparametric estimation from incomplete observations. J. Am. Stat. Assoc. 53, 457-481.
-
(1958)
J. Am. Stat. Assoc.
, vol.53
, pp. 457-481
-
-
Kaplan, E.L.1
Meier, P.2
-
36
-
-
0003089892
-
Benzacridines and dibenzacridines. Metabolism, mutagenicity and carcinogenicity
-
(S. K. Yang and B. D. Silverman, Eds.). CRC Press, Boca Raton
-
Lehr, R. E., Wood, A. W., Levin, W., Conney, A. H., and Jerina, D. M. (1988). Benzacridines and dibenzacridines. Metabolism, mutagenicity and carcinogenicity. In Polycyclic Aromatic Hydrocarbon Carcinogenesis: Structure-Activity Relationships. (S. K. Yang and B. D. Silverman, Eds.), pp. 31-58. CRC Press, Boca Raton.
-
(1988)
Polycyclic Aromatic Hydrocarbon Carcinogenesis: Structure-Activity Relationships
, pp. 31-58
-
-
Lehr, R.E.1
Wood, A.W.2
Levin, W.3
Conney, A.H.4
Jerina, D.M.5
-
37
-
-
0019944571
-
Evaluation of AMSA in previously treated patients with acute leukemia: Results of therapy in 109 adults
-
Legha, S. S., Keating, M. J., McCredie, K. B., Bodey, G. P., and Freireich, E. J. (1982). Evaluation of AMSA in previously treated patients with acute leukemia: Results of therapy in 109 adults. Blood 60, 484-490.
-
(1982)
Blood
, vol.60
, pp. 484-490
-
-
Legha, S.S.1
Keating, M.J.2
McCredie, K.B.3
Bodey, G.P.4
Freireich, E.J.5
-
38
-
-
0023006294
-
Induction of sister chromatid exchanges by inhibitors of topoisomerases
-
Lim, M., Liu, M. F., Jacobson-Kram, D., and Williams, J. R. (1986). Induction of sister chromatid exchanges by inhibitors of topoisomerases. Cell Biol. Toxicol. 2, 485-494.
-
(1986)
Cell Biol. Toxicol.
, vol.2
, pp. 485-494
-
-
Lim, M.1
Liu, M.F.2
Jacobson-Kram, D.3
Williams, J.R.4
-
39
-
-
0024316466
-
DNA topoisomerase poisons as antitumor drugs
-
Liu, L. F. (1989). DNA topoisomerase poisons as antitumor drugs. Annu. Rev. Biochem. 58, 351-375.
-
(1989)
Annu. Rev. Biochem.
, vol.58
, pp. 351-375
-
-
Liu, L.F.1
-
40
-
-
0025943536
-
Carcinogenic properties of pharmaceutical agents evaluated in the IARC monographs programme
-
Marselos, M., and Vainio, H. (1991). Carcinogenic properties of pharmaceutical agents evaluated in the IARC Monographs programme. Carcinogenesis 12, 1751-1766.
-
(1991)
Carcinogenesis
, vol.12
, pp. 1751-1766
-
-
Marselos, M.1
Vainio, H.2
-
41
-
-
0027049136
-
AMSA combination chemotherapy in patients with acute myelogenous leukemia unsuitable for standard antileukemic treatment
-
Maschmeyer, G., Willborn, K., and Heit, W. (1992). AMSA combination chemotherapy in patients with acute myelogenous leukemia unsuitable for standard antileukemic treatment. Leuk. Lymphoma 8, 365-369.
-
(1992)
Leuk. Lymphoma
, vol.8
, pp. 365-369
-
-
Maschmeyer, G.1
Willborn, K.2
Heit, W.3
-
42
-
-
0028310293
-
Characterization of a chemically induced tumor model and the effects of natural killer cell depletion by antiasialo GM-1
-
Mather, G. G., Talcott, P. A., and Exon, J. H. (1994). Characterization of a chemically induced tumor model and the effects of natural killer cell depletion by antiasialo GM-1. Immunobiology 190, 333-345.
-
(1994)
Immunobiology
, vol.190
, pp. 333-345
-
-
Mather, G.G.1
Talcott, P.A.2
Exon, J.H.3
-
43
-
-
0026360043
-
Successful reinduction therapy with amsacrine and cyclocytidine in acute nonlymphoblastic leukemia in children. A report from the childrens cancer study group
-
Miller, L. P., Pyesmany, A. F., Wolff, L. J., Rogers, P. C., Siegel, S. E., Wells, R. J., Buckley, J. D., and Hammond, G. D. (1991). Successful reinduction therapy with amsacrine and cyclocytidine in acute nonlymphoblastic leukemia in children. A report from the Childrens Cancer Study Group. Cancer 67, 2235-2240.
-
(1991)
Cancer
, vol.67
, pp. 2235-2240
-
-
Miller, L.P.1
Pyesmany, A.F.2
Wolff, L.J.3
Rogers, P.C.4
Siegel, S.E.5
Wells, R.J.6
Buckley, J.D.7
Hammond, G.D.8
-
44
-
-
0022514876
-
Isolation of intercalator-dependent protein-linked DNA strand cleavage activity from cell nuclei and identification as topoisomerase II
-
Minford, J., Pommier, Y., Filipski, J., Kohn, K. W., Kerrigan, D., Mattern, M., Michaels, S., Schwartz, R., and Zwelling, L. A. (1986). Isolation of intercalator-dependent protein-linked DNA strand cleavage activity from cell nuclei and identification as topoisomerase II. Biochemistry 25, 9-16.
-
(1986)
Biochemistry
, vol.25
, pp. 9-16
-
-
Minford, J.1
Pommier, Y.2
Filipski, J.3
Kohn, K.W.4
Kerrigan, D.5
Mattern, M.6
Michaels, S.7
Schwartz, R.8
Zwelling, L.A.9
-
45
-
-
0029156694
-
Expression of exposure in negative carcinogenicity studies: Dose/body weight, dose/body surface area, or plasma concentrations?
-
Monro, A., and Mordenti, J. (1995). Expression of exposure in negative carcinogenicity studies: Dose/body weight, dose/body surface area, or plasma concentrations? Toxicologic Pathol. 23, 187-198.
-
(1995)
Toxicologic Pathol.
, vol.23
, pp. 187-198
-
-
Monro, A.1
Mordenti, J.2
-
46
-
-
0003668668
-
-
CAS 952-23-8. Carcinogenesis Technical Report Series 5, DHEW Publication (NIH) 77-805
-
National Cancer Institute (1977). Bioassay of Proflavine for Possible Carcinogenicity. CAS 952-23-8. Carcinogenesis Technical Report Series 5, DHEW Publication (NIH) 77-805.
-
(1977)
Bioassay of Proflavine for Possible Carcinogenicity
-
-
-
47
-
-
0021333644
-
Mechanism of antitumor drug action: Poisoning of mammalian DNA topoisomerase II on DNA by 4′-(9-acridinylamino)-methanesulfon-m-anisidide
-
Nelson, E. M., Tewey, K. M., and Liu, L. F. (1984). Mechanism of antitumor drug action: Poisoning of mammalian DNA topoisomerase II on DNA by 4′-(9-acridinylamino)-methanesulfon-m-anisidide. Proc. Natl. Acad. Sci. USA 81, 1361-1365.
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 1361-1365
-
-
Nelson, E.M.1
Tewey, K.M.2
Liu, L.F.3
-
48
-
-
0017185669
-
Pulmonary carcinogenesis by derivatives of polynuclear aromatic alkylating agents
-
Peck, R. M., Tan, T. K., and Peck, E. B. (1976). Pulmonary carcinogenesis by derivatives of polynuclear aromatic alkylating agents. Cancer Res. 36, 2423-2427.
-
(1976)
Cancer Res.
, vol.36
, pp. 2423-2427
-
-
Peck, R.M.1
Tan, T.K.2
Peck, E.B.3
-
49
-
-
85033066248
-
Subchronic intravenous toxicity of the antineoplastic drug, amsacrine, in male Wistar rats
-
Pegg, D. G., Watkins, J. R., Graziano, M. J., and McKenna, M. J. (1996). Subchronic intravenous toxicity of the antineoplastic drug, amsacrine, in male Wistar rats. Fund. Appl. Toxicol. 32, 45-52.
-
(1996)
Fund. Appl. Toxicol.
, vol.32
, pp. 45-52
-
-
Pegg, D.G.1
Watkins, J.R.2
Graziano, M.J.3
McKenna, M.J.4
-
50
-
-
0019291735
-
Guidelines for simple, sensitive significance tests for carcinogenic effects in long-term animal experiments
-
International Agency for Research on Cancer
-
Peto, R., Pike, M. C., Day, N. E., Gray, R. G., Lee, P. N., Parish, S., Peto, J., Richards, S., and Wahrendorf, J. (1980). Guidelines for simple, sensitive significance tests for carcinogenic effects in long-term animal experiments. In Long-Term and Short-Term Screening assays for Carcinogens: A Critical Appraisal, IARC Monographs Suppl. 2, pp. 311-426. International Agency for Research on Cancer.
-
(1980)
Long-Term and Short-Term Screening Assays for Carcinogens: A Critical Appraisal, IARC Monographs
, Issue.SUPPL. 2
, pp. 311-426
-
-
Peto, R.1
Pike, M.C.2
Day, N.E.3
Gray, R.G.4
Lee, P.N.5
Parish, S.6
Peto, J.7
Richards, S.8
Wahrendorf, J.9
-
51
-
-
0023493551
-
Role of DNA intercalation in the inhibition of purified mouse leukemia (L1210) DNA topoisomerase II by 9-aminoacridines
-
Pommier, Y., Covey, J., Kerrigan, D., Mattes, W., Markovits, J., and Kohn, K. W. (1987). Role of DNA intercalation in the inhibition of purified mouse leukemia (L1210) DNA topoisomerase II by 9-aminoacridines. Biochem. Pharmacol. 36, 3477-3486.
-
(1987)
Biochem. Pharmacol.
, vol.36
, pp. 3477-3486
-
-
Pommier, Y.1
Covey, J.2
Kerrigan, D.3
Mattes, W.4
Markovits, J.5
Kohn, K.W.6
-
52
-
-
0021153767
-
Formation and rejoining of deoxyribonucleic acid double-strand breaks induced in isolated cell nuclei by antineoplastic intercalating agents
-
Pommier, Y., Schwartz, R. E., Kohn, K. W., and Zwelling, L. A. (1984). Formation and rejoining of deoxyribonucleic acid double-strand breaks induced in isolated cell nuclei by antineoplastic intercalating agents. Biochemistry 23, 3194-3201.
-
(1984)
Biochemistry
, vol.23
, pp. 3194-3201
-
-
Pommier, Y.1
Schwartz, R.E.2
Kohn, K.W.3
Zwelling, L.A.4
-
53
-
-
0021631110
-
Carcinogenicity of antineoplastic agents in man
-
Rieche, K. (1984). Carcinogenicity of antineoplastic agents in man. Cancer Treat. Rev. 11, 39-67.
-
(1984)
Cancer Treat. Rev.
, vol.11
, pp. 39-67
-
-
Rieche, K.1
-
54
-
-
0022656381
-
DNA damage by antitumor acridines mediated by mammalian DNA topoisomerase II
-
Rowe, T. C., Chen, G. L., Hsiang, Y.-H., and Liu, L. F. (1986). DNA damage by antitumor acridines mediated by mammalian DNA topoisomerase II. Cancer Res. 46, 2021-2026.
-
(1986)
Cancer Res.
, vol.46
, pp. 2021-2026
-
-
Rowe, T.C.1
Chen, G.L.2
Hsiang, Y.-H.3
Liu, L.F.4
-
55
-
-
0026510803
-
Immunosuppression and cancer: The ciclosporin case
-
Ryffel, B., Mihatsch, M. J., and Fisher, G. L. (1992). Immunosuppression and cancer: The ciclosporin case. Drug Chem. Toxicol. 15, 95-115.
-
(1992)
Drug Chem. Toxicol.
, vol.15
, pp. 95-115
-
-
Ryffel, B.1
Mihatsch, M.J.2
Fisher, G.L.3
-
56
-
-
0026665545
-
Human immunodeficiency virus as a risk factor in miscellaneous cancers
-
Spina, M., and Tirelli, U. (1992). Human immunodeficiency virus as a risk factor in miscellaneous cancers. Curr. Opin. Oncol. 4, 907-910.
-
(1992)
Curr. Opin. Oncol.
, vol.4
, pp. 907-910
-
-
Spina, M.1
Tirelli, U.2
-
57
-
-
0025214172
-
Double intensification with amsacrine/high dose ara-c and high dose chemotherapy with autologous bone marrow transplantation produces durable remissions in acute myelogenous leukemia
-
Spinolo, J. A., Dicke, K. A., Horwitz, L. J., Jagannath, S., Zander, A. R., Auber, M. L., and Spitzer, G. (1990). Double intensification with amsacrine/high dose ara-c and high dose chemotherapy with autologous bone marrow transplantation produces durable remissions in acute myelogenous leukemia. Bone Marrow Transplant 5, 111-118.
-
(1990)
Bone Marrow Transplant
, vol.5
, pp. 111-118
-
-
Spinolo, J.A.1
Dicke, K.A.2
Horwitz, L.J.3
Jagannath, S.4
Zander, A.R.5
Auber, M.L.6
Spitzer, G.7
-
58
-
-
0016759979
-
Tests for trend in life table analysis
-
Tarone, R. E. (1975). Tests for trend in life table analysis. Biometrika 62, 679-682.
-
(1975)
Biometrika
, vol.62
, pp. 679-682
-
-
Tarone, R.E.1
-
59
-
-
0017336302
-
On distribution-free tests for equality of survival distributions
-
Tarone, R. E., and Ware, J. (1977). On distribution-free tests for equality of survival distributions. Biometrika 64, 156-160.
-
(1977)
Biometrika
, vol.64
, pp. 156-160
-
-
Tarone, R.E.1
Ware, J.2
-
60
-
-
77957176959
-
Spontaneous neoplasms in control Wistar rats
-
Walsh, K. M., and Poteracki, J. (1994). Spontaneous neoplasms in control Wistar rats. Fund. Appl. Toxicol. 22, 65-72.
-
(1994)
Fund. Appl. Toxicol.
, vol.22
, pp. 65-72
-
-
Walsh, K.M.1
Poteracki, J.2
-
61
-
-
0023787257
-
Intermediate and high dose Ara-C and m-AMSA for remission induction and consolidation treatment of patients with acute myeloid leukemia: An EORTC leukemia cooperative group phase II study
-
Willemze, R., Jager, U., Jehn, U., Stryckmans, P., Bury, J., Suciu, S., Solbu, G., Zittoun, R., Burghouts, J., Lowenberg, B., Abels, J., and Cauchie, CH. (1988). Intermediate and high dose Ara-C and m-AMSA for remission induction and consolidation treatment of patients with acute myeloid leukemia: An EORTC Leukemia Cooperative Group phase II study. Eur. J. Cancer Clin. Oncol. 24, 1721-1725.
-
(1988)
Eur. J. Cancer Clin. Oncol.
, vol.24
, pp. 1721-1725
-
-
Willemze, R.1
Jager, U.2
Jehn, U.3
Stryckmans, P.4
Bury, J.5
Suciu, S.6
Solbu, G.7
Zittoun, R.8
Burghouts, J.9
Lowenberg, B.10
Abels, J.11
Cauchie, C.H.12
-
62
-
-
0024594243
-
Alternating v repeated postremission treatment in adult acute myelogenous leukemia: A randomized phase III study (AML6) of the EORTC leukemia cooperative group
-
Zittoun, R., Jehn, U., Fiere, D., Haanan, B., Lowenburg, B., Willemze, R., Abels, J., Bury, J., Peetermans, M., Hayat, M., Suciu, S., Solbu, G., and Stryckmans, P. (1989). Alternating v repeated postremission treatment in adult acute myelogenous leukemia: A randomized phase III study (AML6) of the EORTC Leukemia Cooperative Group. Blood 73, 896-906.
-
(1989)
Blood
, vol.73
, pp. 896-906
-
-
Zittoun, R.1
Jehn, U.2
Fiere, D.3
Haanan, B.4
Lowenburg, B.5
Willemze, R.6
Abels, J.7
Bury, J.8
Peetermans, M.9
Hayat, M.10
Suciu, S.11
Solbu, G.12
Stryckmans, P.13
-
63
-
-
0019867969
-
Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4′-(9-acridinylamino)methanesulfon-m-anisidide and adriamycin
-
Zwelling, L. A., Michaels, S., Erickson, L. C., Ungerleider, R. S., Nichols, M., and Kohn, K. W. (1981). Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4′-(9-acridinylamino)methanesulfon-m-anisidide and adriamycin. Biochemistry 20, 6553-6563.
-
(1981)
Biochemistry
, vol.20
, pp. 6553-6563
-
-
Zwelling, L.A.1
Michaels, S.2
Erickson, L.C.3
Ungerleider, R.S.4
Nichols, M.5
Kohn, K.W.6
|