Ozone uptake in healthy adult males during quiet breathing

Fundamental and Applied Toxicology

Volumn 29, Issue 1, 1996, Pages 102-109

  Wiester, M J ^a   Stevens, M A ^d   Menache, M G ^c   McKee Jr , J L ^a   Gerrity, T R ^a,b  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b DEPARTMENT OF VETERANS AFFAIRS   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

OZONE;

ADULT; ARTICLE; BREATHING; DOSIMETRY; HUMAN; HUMAN EXPERIMENT; INHALATION; LUNG GAS EXCHANGE; MALE; NORMAL HUMAN; SPIROMETRY;

EID: 85033058702     PISSN: 02720590     EISSN: None     Source Type: Journal    
DOI: 10.1006/faat.1996.0011     Document Type: Article

References (19)

1. Dungworth, D. L. (1989). Noncarcinogenic responses of the respiratory tract to inhaled toxicants. In Concepts in Inhalation Toxicology (R. O. McClellan and R. F. Henderson, Eds.), pp. 273-298. Hemisphere, Washington, DC/New York.
2. Gerrity, T. R., Biscardi, F., Strong, A. A., and Garlington, R. (1995). Ozone uptake in the conducting airways of humans. Submitted for publication.
3. 3 in tidal-breathing humans. J. Appl. Physiol. 65, 393-400.
4. Gliner, J. A., Horvath, S. M., and Folinsbee, L. J. (1983). Pre-exposure to low ozone concentrations does not diminish the pulmonary function response on exposure to higher ozone concentrations. Am. Rev. Respir. Dis. 127, 51-55.
5. Glover, D. E., Berntsen, J. H., Crider, W. L., and Strong, A. A. (1981). Design and performance of a system to control concentrations of common gaseous air pollutants within environmental laboratories used for human exposure studies. J. Environ. Sci. Health 16, 501-522.
6. Hu, S. C., Ben-Jebna, A., and Ultman, J. S. (1992). Longitudinal distribution of ozone absorption in the lung: Effects of respiratory flow. J. Appl. Physiol. 73, 1655-1667.
7. Lippmann, M. (1989). Health effects of ozone. A critical review. JAPCA 39, 672-695.
8. Mauderly, J. L. (1988). Comparisons of respiratory function responses of laboratory animals and humans. In Inhalation Toxicology: The Design and Interpretation of Inhalation Studies and Their Use in Risk Assessment (U. Mohr, Ed.), pp. 243-269. Springer-Verlag, New York.
9. McDonnell, W. F., Horstman, D. H., Hazucha, M. J., Seal, E., Haak, E. D., Salaam, S. A., and House, D. E. (1983). Pulmonary effects of ozone exposure during exercise: Dose response characteristics. J. Appl. Physiol. Respir. Environ. Exercise Physiol. 54, 1345-1352.
10. McDonnell, W. F., Horstman, D. H., Salaam, S. A., and House, D. E. (1985). Reproducibility of individual responses to ozone exposure. Am. Rev. Respir. Dis. 131, 36-40.
11. Miller, F. J., McNeal, C. A., Kirtz, J. M., Gardner, D. E., Coffin, D. L., and Menzel, D. B. (1979). Nasopharyngeal removal of ozone in rabbits and guinea pigs. Toxicology 14, 273-281.
12. Moorman, W. J., Chmiel, J. J., Stara, J. F., and Lewis, T. R. (1973). Comparative decomposition of ozone in the nasopharynx of beagles: Acute vs. chronic exposure. Arch. Environ. Health 26, 153-155.
13. Tepper, J. S., Costa, D. L., Lehmann, J. R., Weber, M. F., and Hatch, G. E. (1989). Unattenuated structural and biochemical alterations in the rat lung during functional adaptation to ozone. Am. Rev. Respir. Dis. 140, 493-501.
14. Vaughan, T. R., Jennelle, L. F., and Lewis, T. R. (1969). Long-term exposure to low levels of air pollutants. Arch. Environ. Health 19, 45-50.
15. Warheit, D. B. (1989). Interspecies comparisons of lung responses to inhaled particles and gases. Crit. Rev. Toxicol. 20(1), 1-29.
16. Wiester, M. J., Tepper, J. S., Doerfler, D. L., and Costa, D. L. (1995). Ozone adaptation in rats after chronic exposure to a stimulated urban profile of ozone. Fundam. Appl. Toxicol. 24, 42-51.
17. 3) uptake in three strains of rats and in the guinea pig. Toxicol. Appl. Pharmacol. 96, 140-146.
18. Wiester, M. J., Williams, T. B., King, M. E., Menache, M. G., and Miller, F. J. (1987). Ozone uptake in awake Sprague-Dawley rats. Toxicol. Appl. Pharmacol. 89, 429-437.
19. Yokoyama, E., and Frank, R. (1972). Respiratory uptake of ozone in dogs. Arch. Environ. Health 25, 132-138.