Evaluating lead bioavailability data by means of a physiologically based lead kinetic model

Fundamental and Applied Toxicology

Volumn 29, Issue 1, 1996, Pages 63-70

  Polak J ^a   O'Flaherty, E J ^a   Freeman, G B ^b   Johnson, J D ^b   Liao, S C ^b   Bergstrom, P D ^c  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b BATTELLE MEMORIAL INSTITUTE   (United States)

^c BP EXPLORATION   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

LEAD; LEAD ACETATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOAVAILABILITY; BLOOD; BONE; CONTROLLED STUDY; FEMALE; MALE; MODEL; NONHUMAN; RAT; SOIL POLLUTION; TOXICOKINETICS;

ANIMALIA;

EID: 85033038376     PISSN: 02720590     EISSN: None     Source Type: Journal    
DOI: 10.1006/faat.1996.0006     Document Type: Article

References (15)

1. Aungst, B. J., Dolce, J. A., and Fung, H.-L. (1981). The effect of dose on the disposition of lead in rats after intravenous and oral administration. Toxicol. Appl. Pharmacol. 61, 48-57.
2. Barltrop, D., and Meek, F. (1979). Effect of particle size on lead absorption from the gut. Arch. Environ. Health 34, 280-285.
3. Chaney, R. L. (1991). Soil lead chemistry in relation to bioavailability of lead in soil and dust. In Proceedings, Symposium on Bioavailability and Dietary Uptake of Lead (R. Cothern and R. W. Elias, Eds.), Research Triangle Park, NC.
4. Forbes, G. B., and Reina, J. C. (1972). Effect of age on gastrointestinal absorption (Fe, Sr, Pb) in the rat. J. Nutr. 102, 647-652.
5. Freeman, G. B., Johnson, J. D., Killinger, J. M., Liao, S. C., Feder, P. I., Davis, A. O., Ruby, M. V., Chaney, R. L., Lovre, S. C., and Bergstrom, P. D. (1992). Relative bioavailability of lead from mining waste soil in rats. Fundam. Appl. Toxicol. 19, 388-398.
6. Freeman, G. B., Liao, S. C., Feder, P. I., Trigg, N. J., and Johnson, J. D. (1993). Absolute Bioavailability of Lead Following Dosed Feed Mine Waste Administration in Sprague - Dawley Rats. Draft Final Report to Atlantic Richfield Company, Battelle Study No. SC920179.
7. Freeman, G. B., Johnson, J. D., Liao, S. C., Feder, P. I., Davis, A. O., Ruby, M. V., Schoof, R. A., Chaney, R. L., and Bergstrom, P. D. (1994). Absolute bioavailability of lead acetate and mining waste lead in rats. Toxicology 91, 151-163.
8. Ghantous, H., Bingham, T., McCleary, K., and Bogdanffy, M. (1994). Microswine as a model for lead bioavailability in children. Toxicologist 14, 157. [Abstract]
9. Klaassen, C. D., and Shoeman, D. W. (1974). Biliary excretion of lead in rats, rabbits, and dogs. Toxicol. Appl. Pharmacol. 29, 434-446.
10. Mahaffey, K. R., Goyer, R., and Haseman, J. K. (1973). Dose-response to lead ingestion in rats fed low dietary calcium. J. Lab. Clin. Med. 82, 92-100.
11. O'Flaherty, E. J. (1991). Physiologically based models for bone-seeking elements. II. Kinetics of lead disposition in rats. Toxicol. Appl. Pharmacol. 111, 313-331.
12. Rabinowitz, M. B., Kopple, J. D., and Wetherill, G. W. (1980). Effect of food intake and fasting on gastrointestinal lead absorption in humans. Am. J. Clin. Nutr. 33, 1784-1788.
13. Simons, T. J. B. (1993). Lead transport and binding by human erythrocytes in vitro. Pflügers Arch. 423, 307-313.
14. Steele, M. J., Beck, B. D., Murphy, B. L., and Strauss, H. S. (1990). Assessing the contribution from lead in mining waste to blood lead. Regul. Toxicol. Pharmacol. 11, 158-190.
15. Weis, C. P., Poppenga, R. L., Thacker, B. J., Henningsen, G. M., Curtis, A., Jolly, R., and Harpstead, T. (1994). Pharmacokinetics of soil - lead absorption into immature swine following subchronic oral and IV exposure. Toxicologist 14, 119. [Abstract]