A data-driven approach links microglia to pathology and prognosis in amyotrophic lateral sclerosis

Acta neuropathologica communications

Volumn 5, Issue 1, 2017, Pages 23-

  Cooper Knock, Johnathan ^a   Green, Claire ^a   Altschuler, Gabriel ^a   Wei, Wenbin ^a   Bury, Joanna J ^a   Heath, Paul R ^a   Wyles, Matthew ^a   Gelsthorpe, Catherine ^a   Highley, J Robin ^a   Lorente Pons, Alejandro ^a   Beck, Tim ^a   Doyle, Kathryn ^a   Otero, Karel ^a   Traynor, Bryan ^a   Kirby, Janine ^a   Shaw, Pamela J ^a   Hide, Winston ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Amyotrophic lateral sclerosis; Biomarkers; Microglia; Neuropathology; Transciptome; TREM2

Indexed keywords

BIOLOGICAL MARKER; IMMUNOGLOBULIN RECEPTOR; MEMBRANE PROTEIN; TREM2 PROTEIN, HUMAN;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; BRAIN; CELL LINE; COHORT ANALYSIS; DISEASE COURSE; FEMALE; GENETICS; GENOME-WIDE ASSOCIATION STUDY; HUMAN; LYMPHOCYTE; MALE; METABOLISM; MICROGLIA; MIDDLE AGED; MOTONEURON; PATHOLOGY; PROGNOSIS; SPINAL CORD; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; AMYOTROPHIC LATERAL SCLEROSIS; BIOMARKERS; BRAIN; CELL LINE; COHORT STUDIES; DISEASE PROGRESSION; FEMALE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LYMPHOCYTES; MALE; MEMBRANE GLYCOPROTEINS; MICROGLIA; MIDDLE AGED; MOTOR NEURONS; PROGNOSIS; RECEPTORS, IMMUNOLOGIC; SPINAL CORD;

EID: 85032152754     PISSN: None     EISSN: 20515960     Source Type: Journal    
DOI: 10.1186/s40478-017-0424-x     Document Type: Article

References (0)