Cardiac MR With Late Gadolinium Enhancement in Acute Myocarditis With Preserved Systolic Function: ITAMY Study

Journal of the American College of Cardiology

Volumn 70, Issue 16, 2017, Pages 1977-1987

  Aquaro, Giovanni Donato ^a   Perfetti, Matteo ^a   Camastra, Giovanni ^b   Monti, Lorenzo ^c   Dellegrottaglie, Santo ^d,e   Moro, Claudio ^f   Pepe, Alessia ^a   Todiere, Giancarlo ^a   Lanzillo, Chiara ^g   Scatteia, Alessandra ^h   Di Roma, Mauro ⁱ   Pontone, Gianluca ^j   Perazzolo Marra, Martina ^k   Barison, Andrea ^a   Di Bella, Gianluca ^l  

^a FONDAZIONE TOSCANA GABRIELE MONASTERIO   (Italy)

^b Vannini Hospital   (Italy)

^c HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^d Division of Cardiology   (Italy)

^e MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^f DESIO HOSPITAL   (Italy)

^g Cardiology Department   (Italy)

^h UNIVERSITY OF NAPLES FEDERICO II   (Italy)

ⁱ EUROPEAN HOSPITAL   (Italy)

^j CENTRO CARDIOLOGICO MONZINO   (Italy)

^k UNIVERSITY OF PADOVA   (Italy)

^l UNIVERSITY OF MESSINA   (Italy)

more..

Author keywords

acute myocarditis; cardiac magnetic resonance; late gadolinium enhancement; prognosis

Indexed keywords

GADOLINIUM; RADIOISOTOPE;

ACUTE DISEASE; ADULT; ARTICLE; CARDIAC IMAGING; CARDIOVASCULAR MAGNETIC RESONANCE; CONTRAST ENHANCEMENT; DISEASE MARKER; FEMALE; HEART ARREST; HEART DEATH; HEART FAILURE; HEART HEMODYNAMICS; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MYOCARDITIS; PRESERVED LEFT VENTRICULAR EJECTION FRACTION; PRIORITY JOURNAL; PROGNOSIS; RESUSCITATION; CINE MAGNETIC RESONANCE IMAGING; CLINICAL TRIAL; CORONARY ANGIOGRAPHY; DIAGNOSTIC IMAGING; FOLLOW UP; HEART LEFT VENTRICLE FUNCTION; ITALY; MIDDLE AGED; MULTICENTER STUDY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES;

ACUTE DISEASE; ADULT; CORONARY ANGIOGRAPHY; FEMALE; FOLLOW-UP STUDIES; GADOLINIUM; HUMANS; ITALY; MAGNETIC RESONANCE IMAGING, CINE; MALE; MIDDLE AGED; MYOCARDITIS; RADIOISOTOPES; VENTRICULAR FUNCTION, LEFT;

EID: 85031719512     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2017.08.044     Document Type: Article

References (23)

1. Aretz, H.T., Billingham, M.E., Edwards, W.D., et al. Myocarditis: a histopathologic definition and classification. Am J Cardiovasc Pathol 1 (1987), 3–14.
2. Leone, O., Veinot, J.P., Angelini, A., et al. 2011 consensus statement on endomyocardial biopsy from the Association for European Cardiovascular Pathology and the Society for Cardiovascular Pathology. Cardiovasc Pathol 21 (2012), 245–274.
3. Caforio, A.L., Pankuweit, S., Arbustini, E., et al. Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. Eur Heart J 34 (2013), 2636–2648 2648a–d.
4. Kindermann, I., Barth, C., Mahfoud, F., et al. Update on myocarditis. J Am Coll Cardiol 59 (2012), 779–792.
5. Friedrich, M.G., Sechtem, U., Schulz-Menger, J., et al. Cardiovascular magnetic resonance in myocarditis: a JACC white paper. J Am Coll Cardiol 53 (2009), 1475–1487.
6. Sanguineti, F., Garot, P., Mana, M., et al. Cardiovascular magnetic resonance predictors of clinical outcome in patients with suspected acute myocarditis. J Cardiovasc Magn Reson, 17, 2015, 78.
7. Grün, S., Schumm, J., Greulich, S., et al. Long-term follow-up of biopsy-proven viral myocarditis: predictors of mortality and incomplete recovery. J Am Coll Cardiol 59 (2012), 1604–1615.
8. Cheong, B.Y., Muthupillai, R., Wilson, J.M., et al. Prognostic significance of delayed-enhancement magnetic resonance imaging: survival of 857 patients with and without left ventricular dysfunction. Circulation 120 (2009), 2069–2076.
9. Wong, T.C., Piehler, K.M., Zareba, K.M., et al. Myocardial damage detected by late gadolinium enhancement cardiovascular magnetic resonance is associated with subsequent hospitalization for heart failure. J Am Heart Assoc, 2, 2013, e000416.
10. Mahrholdt, H., Goedecke, C., Wagner, A., et al. Cardiovascular magnetic resonance assessment of human myocarditis: a comparison to histology and molecular pathology. Circulation 109 (2004), 1250–1258.
11. Mahrholdt, H., Wagner, A., Deluigi, C.C., et al. Presentation, patterns of myocardial damage, and clinical course of viral myocarditis. Circulation 114 (2006), 1581–1590.
12. Abdel-Aty, H., Boye, P., Zagrosek, A., et al. Diagnostic performance of cardiovascular magnetic resonance in patients with suspected acute myocarditis: comparison of different approaches. J Am Coll Cardiol 45 (2005), 1815–1822.
13. Perfetti, M., Malatesta, G., Alvarez, I., et al. A fast and effective method to assess myocardial hyperemia in acute myocarditis by magnetic resonance. Int J Cardiovasc Imaging 30 (2014), 629–637.
14. Hundley, W.G., Bluemke, D.A., Finn, J.P., et al. ACCF/ACR/AHA/NASCI/SCMR 2010 expert consensus document on cardiovascular magnetic resonance: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents. J Am Coll Cardiol 55 (2010), 2614–2662.
15. Di Bella, G., Siciliano, V., Aquaro, G.D., et al. Scar extent, left ventricular end-diastolic volume, and wall motion abnormalities identify high-risk patients with previous myocardial infarction: a multiparametric approach for prognostic stratification. Eur Heart J 34 (2013), 104–111.
16. Aquaro, G.D., Camastra, G., Monti, L., et al. Reference values of cardiac volumes, dimensions, and new functional parameters by MR: a multicenter, multivendor study. J Magn Reson Imaging 45 (2017), 1055–1067.
17. Francone, M., Chimenti, C., Galea, N., et al. CMR sensitivity varies with clinical presentation and extent of cell necrosis in biopsy-proven acute myocarditis. J Am Coll Cardiol Img 7 (2014), 254–263.
18. Schumm, J., Greulich, S., Wagner, A., et al. Cardiovascular magnetic resonance risk stratification in patients with clinically suspected myocarditis. J Cardiovasc Magn Reson, 16, 2014, 14.
19. Shirani, J., Freant, L.J., Roberts, W.C., Gross and semiquantitative histologic findings in mononuclear cell myocarditis causing sudden death, and implications for endomyocardial biopsy. Am J Cardiol 72 (1993), 952–957.
20. De Bolle, L., Van Loon, J., De Clercq, E., Naesens, L., Quantitative analysis of HHV6 cell tropism. J Med Virol 75 (2005), 76–85.
21. Zerr, D.M., Meier, A.S., Selke, S.S., A population-based study of primary HHV6 infection. N Engl J Med 352 (2005), 768–776.
22. Young, N.S., Brown, K.E., Parvovirus B19. N Engl J Med 350 (2004), 586–597.
23. Lurz, P., Eitel, I., Adam, J., et al. Diagnostic performance of CMR imaging compared with EMB in patients with suspected myocarditis. J Am Coll Cardiol Img 5 (2012), 513–524.