Topical application of the anti-microbial chemical triclosan induces immunomodulatory responses through the S100A8/A9-TLR4 pathway

Journal of Immunotoxicology

Volumn 14, Issue 1, 2017, Pages 50-59

  Marshall, Nikki B ^a   Lukomska, Ewa ^a   Nayak, Ajay P ^a   Long, Carrie M ^a,b   Hettick, Justin M ^a   Anderson, Stacey E ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^b WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Immunomodulation; Innate immunity; TLR4; Triclosan

Indexed keywords

CALGRANULIN A; CALGRANULIN B; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 6; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 6; TRICLOSAN; TUMOR NECROSIS FACTOR; ALLERGEN; ANTIINFECTIVE AGENT; BLOCKING ANTIBODY; CYTOKINE; TLR4 PROTEIN, MOUSE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DRUG EXPOSURE; FEMALE; IMMUNOMODULATION; IN VIVO STUDY; INNATE IMMUNITY; LEUKOCYTE; LYMPH NODE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN INFILTRATE; T LYMPHOCYTE; TH2 CELL; TLR SIGNALING; ANIMAL; BAGG ALBINO MOUSE; CELL CULTURE; DISEASE MODEL; HUMAN; HYPERSENSITIVITY; IMMUNOLOGY; METABOLISM; SIGNAL TRANSDUCTION; SKIN; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ALLERGENS; ANIMALS; ANTI-INFECTIVE AGENTS; ANTIBODIES, BLOCKING; CALGRANULIN A; CALGRANULIN B; CELLS, CULTURED; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; HYPERSENSITIVITY; IMMUNITY, INNATE; IMMUNOMODULATION; MICE; MICE, INBRED BALB C; SIGNAL TRANSDUCTION; SKIN; TH2 CELLS; TOLL-LIKE RECEPTOR 4; TRICLOSAN;

EID: 85031696278     PISSN: 1547691X     EISSN: 15476901     Source Type: Journal    
DOI: 10.1080/1547691X.2016.1258094     Document Type: Article

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