The biophysical properties of mucus

Therapy for Mucus-Clearance Disorders

Volumn , Issue , 2004, Pages 29-41

  King, Malcolm ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85031335388     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (43)

1. Dasgupta B, King M. Molecular basis for mucolytic therapy. Can Respir J 1995; 2:223-230.
2. Rubin BK, Tomkiewicz RP, King M. Mucoactive agents: old and new. In: Wilmott RW, ed. The Pediatric Lung. Basel, Switzerland: Birkhàuser, 1997:155-179.
3. King M. Mucus, mucociliary clearance and coughing. In: Bates DV. ed. Respiratory Function in Disease. 3rd ed. Philadelphia: Saunders, 1989:69-78.
4. King M, Rubin BK. Rheology of airway mucus: relationship with clearance function. In: Takishima T, Shimura S, eds. Airway Secretion: Physiological Bases for the Control of Mucous Hypersecretion. New York: Marcel Dekker, 1994:283-314.
5. King M, Rubin BK. Mucus physiology and pathophysiology: therapeutic aspects. In: Derenne JP, Whitelaw WA, Similowski T, eds. Acute Respiratory Failure in COPD. New York: Marcel Dekker, 1996:391-411.
6. Lutz RJ, Litt M, Chakrin LW. Physical-chemical factors in mucus rheology. In: Gabelnick HL. Litt M, eds. Rheology of Biological Systems. Springfield, 1L: Charles C Thomas, 1973:158-194.
7. Lamblin G, Aubert JP, Perini JM, Klein N, Porchet N, Degand P, Roussel P. Human respiratory mucins. Eur Respir J 1992; 5:247-256.
8. Bansil R, Stanley E, LaMont JT. Mucin biophysics. Annu Rev Physiol 1995; 57: 635-657.
9. King M. Macklem PT. Rheological properties of microliter quantities of normal mucus. J Appl Physiol 1977; 42:797-802.
10. Meyer FA, Gelman RA. Mucociliary transference rate and mucus viscoelasticity: dependence on dynamic storage and loss modulus. Am Rev Respir Dis 1979; 120: 553-557.
11. Dasgupta B. Tomkiewicz RP, De Sanctis GT, Boyd WA, King M. Rheological properties in cystic fibrosis airway secretions with combined rhDNase and gelsolin treatment. In: Singh M, Saxena VP, eds. Advances in Physiological Fluid Dynamics. New Delhi, India: Narosa. 1996:74-78.
12. Dulfano MJ, Adler KB. Physical properties of sputum. VII. Rheologic properties and mucociliary transport. Am Rev Respir Dis 1975; 112:341-347.
13. Shih CK, Litt M, Khan MA, Wolf DP. Effect of nondialyzable solids concentration and viscoelasticity on ciliary transport of tracheal mucus. Am Rev Respir Dis 1975; 115:89-995.
14. King M. Relationship between mucus viscoelasticity and ciliary transport in guaran gel/frog palate model system. Biorheology 1980; 17:249-254.
15. Puchelle E, Zahm JM, Duvivier C. Spinability of bronchial mucus: relationship with viscoelasticity and mucus transport properties. Biorheology 1983; 20:239-249.
16. King M, Zahm JM, Pierrot D, Vaquez-Girod S, Puchelle E. The role of mucus gel viscosity, spinnability, and adhesive properties in clearance by simulated cough. Biorheology 1989: 26:737-745.
17. King M, Dasgupta B, Tomkiewicz RP, Brown NE. Rheology of cystic fibrosis sputum after in vitro treatment with hypertonic saline alone and in combination with rhDNase. Am J Respir Crit Care Med 1997; 156:173-177.
18. Agarwal M, King M. Rubin BK, Shukla JB. Mucus transport in a miniaturized simulated cough machine: effect of constriction and serous layer simulant. Biorheology 1989; 26:977-988.
19. Zahm JM, Pierrot D, Vaquez-Girod S, Duvivier C, King M, Puchelle E. The role of mucus sol phase in clearance by simulated cough. Biorheology 1989; 26:747-752.
20. Girod S, Galabert C, Pierrot D. Boissonade MM. Zahm JM, Baszkin A. Puchelle E. Role of phospholipid lining on respiratory mucus clearance by cough. J Appl Physiol 1991; 71:2262-2266.
21. Schürch S, Gehr P, Im Hof V, Geiser M, Green F. Surfactant displaces particles toward the epithelium in airways and alveoli. Respir Physiol 1990; 80:17-32.
22. Allegra L, Bossi R, Braga PC. Influence of surfactant on mucociliary transport. Eur J Respir Dis 1985; 67(suppl 142):71-76.
23. Rubin BK, Ramirez O, King M. The role of mucus rheology and transport in neonatal respiratory distress syndrome and the effect of surfactant therapy. Chest 1992; 101:1080-1085.
24. De Sanctis GT, Tomkiewicz RP, Rubin BK, Schürch S, King M. Exogenous surfactant enhances mucociliary clearance in the anesthetized dog. Eur Respir J 1994; 7: 1616-1621.
25. Braga PC. Sinusoidal oscillations method. In: Braga PC, Allegra L, eds. Methods in Bronchial Mucology. New York: Raven Press, 1988:63-71.
26. Davis SS. Practical applications of viscoelasticity measurement. Eur J Respir Dis1980; 61(suppl 110):141-156.
27. Kim CS. Capillary type viscometer. In: Braga PC, Allegra L. eds. Methods in Bronchial Mucology. New York: Raven Press, 1988:93-103.
28. Leikauf GD, Ueki IF, Nadel JA. Autonomic regulation of viscoelasticity of cat tracheal gland secretion. J Appl Physiol 1984; 56:426-430.
29. King M. Magnetic microrheometer. In: Braga PC, Allegra L, eds. Methods in Bronchial Mucology. New York: Raven Press, 1988:3-83.
30. Majima Y, Hirata K, Takeuchi K, Hattori M, Sakakura Y. Effects of orally administered drugs on dynamic viscoelasticity of human nasal mucus. Am Rev Respir Dis1990; 141:79-83.
31. Silveira PSP. Bbhm GM. Yang HM. Wen CL, Guimar(atilde)es ET, Parada MAC, King M, Saldiva PHN. Computer-assisted rheological evaluation of microsamples of mucus. Comput Methods Programs Biomed 1992; 39:51-60.
32. Zahm JM, Puchelle E, Duvivier C. Didelon J. Spinability of respiratory mucus. Validation of a new apparatus: the Filancemeter. Bull Eur Physiopathol Respir1986; 22:609-613.
33. Blake JR. Winet H. On the mechanics of mucociliary transport. Biorheology 1980; 17:125-134.
34. King M, Agarwal M, Shukla JB. A planar model for mucociliary transport: effect of mucus viscoelasticity. Biorheology 1993; 30:49-61.
35. Gil J, Weibel ER. Extracellular lining of bronchioles after perfusion-fixation of rat lungs for electron microscopy. Anal Rec 1971; 169:185-200.
36. Van As A. Pulmonary airway clearance mechanisms: a reappraisal [editorial]. Am Rev Respir Dis 1977; 115:721-726.
37. Boucher RC, Stutts MJ, Bromberg PA, Gatzy JT. Regional differences in airway surface liquid composition. J Appl Physiol 1981; 50:613-620.
38. Boucher RC. State of the art: human airway ion transport. Am J Respir Crit Care Med 1994; 150:271-281. 581-593.
39. Widdicombe JH. Ion and fluid transport by airway epithelium. In: Takishima T, Shimura S, eds. Airway Secretion: Physiological Bases for the Control of Mucus Hypersecretion. New York: Marcel Dekker, 1994:399-431.
40. Govindaraju K, Cowley EA, Eidelman DH. Lloyd DK. Analysis of proteins in micro samples of rat airway surface fluid by capillary electrophoresis. J Chromatog B Biomed Sci Appl 1998; 705:223-230.
41. King M. Role of mucus viscoelasticity in cough clearance. Biorheology 1987; 24: 589-597.
42. King M. Brock G. Lundell C. Clearance of mucus by simulated cough. J Appl Physiol 1985; 58:1776-1782.
43. Zahm JM. King M. Duvivier C, Pierrot D, Girod S, Puchelle E. Role of simulated repetitive coughing in mucus clearance. Eur Respir J 1991; 4:311-315.