Discovery of an O-mannosylation pathway selectively serving cadherins and protocadherins

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 42, 2017, Pages 11163-11168

  Larsen, Ida Signe Bohse ^a   Narimatsu, Yoshiki ^a   Joshi, Hiren Jitendra ^a   Siukstaite, Lina ^a   Harrison, Oliver J ^b   Brasch, Julia ^b   Goodman, Kerry M ^b   Hansen, Lars ^a   Shapiro, Lawrence ^b   Honig, Barry ^b   Vakhrushev, Sergey Y ^a   Clausen, Henrik ^a   Halim, Adnan ^a,c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b Columbia University ^*  (United States)

^c ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Gene editing; Glycoproteomics; Glycosyltransferase; Mass spectrometry; O glycosylation

Indexed keywords

CADHERIN; GLYCOPROTEIN; MANNOSE; MANNOSYLTRANSFERASE; PLEXIN; PROTOCADHERIN; SCATTER FACTOR RECEPTOR; UNCLASSIFIED DRUG; CARRIER PROTEIN; GLYCOSYLTRANSFERASE; MEMBRANE PROTEIN; TMTC1 PROTEIN, HUMAN; TMTC3 PROTEIN, HUMAN;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL INTERACTION; CHO CELL LINE; COBBLESTONE LISSENCEPHALY; CRISPR-CAS9 SYSTEM; CUPRIAVIDUS METALLIDURANS; EMBRYO; GLYCOSYLATION; HEK293 CELL LINE; HUMAN; HUMAN CELL; MANNOSYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEOMICS; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; TETRATRICOPEPTIDE REPEAT; GENETICS; METABOLISM; MULTIGENE FAMILY;

CADHERINS; CARRIER PROTEINS; GLYCOSYLATION; GLYCOSYLTRANSFERASES; HEK293 CELLS; HUMANS; MANNOSE; MEMBRANE PROTEINS; MULTIGENE FAMILY;

EID: 85031317570     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1708319114     Document Type: Article

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