Monte carlo methods and mathematical models for the dosimetry of skeleton and bone marrow

Therapeutic Applications of Monte Carlo Calculations in Nuclear Medicine

Volumn , Issue , 2002, Pages 286-309

  Bouchet, Lionel G ^a   Bolch, Wesley E ^a   Stabin, Michael ^b   Eckerman, Keith F ^c   Poston, John W ^d   Brill, A Bertrand ^b  

^a UNIVERSITY OF FLORIDA   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c OAK RIDGE NATIONAL LABORATORY   (United States)

^d Texas AandM University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85031159869     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (82)

1. Gray H 1974 Gray’s Anatomy (Philadelphia, PA: Running)
2. ICRP 1995 Basic anatomical and physiological data for use in radiological protection: the skeleton ICRP Publication 70, International Commission on Radiological Protection (Oxford: Pergamon)
3. Rowland R E, Stehney A F and Lucas H F 1978 Dose-response relationships for female radium dial workers Radiat. Res. 76 368-83
4. Littman M S, Kirsh I E and Keane A T 1978 Radium-induced malignant-tumors of mastoid and para-nasal sinuses Am. J. Roentgenol. 131 773-85
5. Rowland R E, Stehney A F and Lucas H F 1983 Dose-response relationships for radium-induced bone sarcomas Health Phys. 44 15-31
6. Beddoe A H 1976 The Microstructure of Mammalian Bone in Relation to the Dosimetry of Bone-Seeking Radionuclides (Leeds: University of Leeds)
7. Lewington V J 1996 Cancer therapy using bone-seeking isotopes Phys. Med. Biol. 41 2027-42
8. Siegel J A, Wessels B W, Watson E E, Stabin M, Vriesendorp H M, Bradley E W, Badger C C, Brill A B, Kwok C, Stickney D R, Eckerman K F, Fisher D R, Buchsbaum D J and Order S E 1990 Bone marrow dosimetry and toxicity for radioimmunotherapy Ab. Immunconj. Radiopharm. 3 213-33
9. Sgouros G 1993 Bone marrow dosimetry for radioimmunotherapy: theoretical considerations J. Nucl. Med. 34 689-94
10. Sgouros G, Stabin M, Erdi Y, Akabani G, Kwok C, Brill A B and Wessels B 2000 Red marrow dosimetry for radiolabeled antibodies that bind to marrow, bone, or blood components Med. Phys. 27 2150-64
11. Shen S, DeNardo G L, Sgouros G, O’Donnell R T and DeNardo S J 1999 Practical determination of patient-specific marrow dose using radioactivity concentration in blood and body J. Nucl. Med. 40 2102-6
12. Loevinger R, Budinger T F and Watson E E 1991 MIRD Primer for Absorbed Dose Calculations (New York: Society of Nuclear Medicine)
13. Siegel J A, Lee R E, Pawlyk D A, Horowitz J A, Sharkey R M and Goldenberg D M 1989 Sacral scintigraphy for bone marrow dosimetry in radioimmunotherapy Int. J. Radiat. Appl. Instrum. B 16 553-9
14. Snyder W S, Ford M R, Warner G G and Watson S B 1975 MIRD Pamphlet No 11:‘S’, absorbed dose per unit cumulated activity for selected radionuclides and organs (New York: Society of Nuclear Medicine)
15. Snyder W S, Ford M R and Warner G G 1978 MIRD Pamphlet No 5, Revised: Estimates of specific absorbed fractions for photon sources uniformly distributed in various organs of a heterogeneous phantom (New York: Society of Nuclear Medicine)
16. CristyMand Eckerman K F 1987 Specific absorbed fractions of energy at various ages from internal photon sources ORNL/TM-8381 (Oak Ridge, TN: Oak Ridge National Laboratory)
17. Clairand I, Bouchet L G and Bolch W E 2000 A new macroscopic model of the long bones for skeletal dosimetry J. Nucl. Med. 41 1062
18. Snyder W S, Ford M R, Warner G G and Watson S B 1974 A tabulation of dose equivalent per microcurie-day for source and target organs of an adult for various radionuclides ORNL-5000 (Oak Ridge, TN: Oak Ridge National Laboratory)
19. Eckerman K F 1985 Aspects of the dosimetry of radionuclides within the skeleton with particular emphasis on the active marrow. In Proceedings of the Fourth International Radiopharmaceutical Dosimetry Symposium eds A T Schlafke-Stelson and E E Watson (Oak Ridge, TN: ORAU) pp 514-34
20. Eckerman K F and Stabin M 2000 Electron absorbed fractions and dose conversion factors for marrow and bone by skeletal regions Health Phys. 78 199-214
21. Stabin M 1996 MIRDOSE: personal computer software for internal dose assessment in nuclear medicine J. Nucl. Med. 37 538-46
22. Bouchet L G, Clairand I and Bolch W E 2000 Improvement of skeletal dosimetry associated with photon sources J. Nucl. Med. 41 1049
23. Beddoe A H, Darley P J and Spiers F W 1976 Measurements of trabecular bone structure in man Phys. Med. Biol. 21 589-607
24. Darley P J 1968 Measurement of linear path length distributions in bone and bone marrow using a scanning technique. In Symposium on Microdosimetry EAEC Report EUR 3747 Ispra, Italy pp 509-26
25. Darley P J 1972 An Investigation of the Structure of Trabecular Bone in Relation to the Radiation Dosimetry of Bone-Seeking Radionuclides (Leeds: University of Leeds)
26. Whitwell J R 1973 Theoretical Investigations of Energy Loss by Ionizing Particles in Bone (Leeds: University of Leeds)
27. Whitwell J R and Spiers F W 1976 Calculated beta-ray dose factors for trabecular bone Phys. Med. Biol. 21 16-38
28. Spiers F W 1949 The influence of energy absorption and electron range on dosage in irradiated bone Br. J. Radiol. 22 521-33
29. Spiers FW 1966 A review of the theoretical and experimental methods of determining radiation dose in bone Br. J. Radiol. 39 216-21
30. Bouchet L G, Jokisch DWand BolchWE 1999 A three-dimensional transport model for determining absorbed fractions of energy for electrons within trabecular bone J. Nucl. Med. 40 1947-66
31. Howell RW, Wessels BW, Loevinger R, Watson E E, BolchWE, Brill A B, Charkes N D, Fisher D R, Hays M T, Robertson J S, Siegel J A and Thomas S R 1999 The MIRD perspective 1999 J. Nucl. Med. 40 3S-10S
32. ICRP 1979 Limits for intakes of radionuclides by workers Publication 30, Part 1. International Commission on Radiological Protection (Oxford: Pergamon)
33. Chen H T and Poston JW 1982 Estimates of absorbed energy in trabecular bone due to beta-particles or electrons Health Phys. 43 647-53
34. Zuzarte de Mendonca A 1993 Trabecular Bone Dosimetry Using a Monte Carlo Code (College Station, TX: Texas A&M University)
35. Nelson W R, Hirayama R H and Roger D W O 1985 The EGS4 code system SLAC Report 265 (Stanford, CA: Stanford Linear Accelerator Center)
36. Parry R A 1995 Revised Estimates of Electron Absorbed Fractions and Radionuclide SValues in Trabecular Bone (College Station, TX: Texas A&M University)
37. Bielajew A F and Rogers D W O 1987 PRESTA, the ‘parameter reduced electron step transport algorithm’ for electron Monte Carlo transport Nucl. Instrum. Meth. B 18 165-81
38. Bouchet L G, Bolch W E, Howell R W and Rao D V 2000 S values for radionuclides localized within the skeleton J. Nucl. Med. 41 189-212
39. Patton P 2000 NMR Microscopy for Skeletal Dosimetry: an Investigation of Marrow Cellularity on Dose Estimates (Gainesville, FL: University of Florida)
40. Stabin M, Eckerman K F, Bolch W E, Bouchet L G and Patton P W 2002 Evolution and status of bone and marrow dose models Cancer Biother. Radiopharmaceut. In press
41. Samaratunga R C, Thomas S R, Hinnefeld J D, Von Kuster L C, Hyams D M, Moulton J S, Sperling M I and Maxon H R 1995 A Monte Carlo simulation model for radiation dose to metastatic skeletal tumor from rhenium-186(Sn)-HEDP J. Nucl. Med. 36 336-50
42. Jokisch D W, Patton P W, Inglis B A, Bouchet L G, Rajon D A, Rifkin J and Bolch W E 1998 NMR microscopy of trabecular bone and its role in skeletal dosimetry Health Phys. 75 584-96
43. Jokisch D W, Bouchet L G, Patton P W, Rajon D A and Bolch W E 2001 Betaparticle dosimetry of the trabecular skeleton using Monte Carlo transport within 3D digital images Med. Phys. 28 1505-18
44. Bolch W E, Patton P W, Rajon D A, Shah A P, Jokisch D W and Inglis B A 2002 Considerations of marrow cellularity in 3-dimensional dosimetric models of the trabecular skeleton J. Nucl. Med. 43 97-108
45. Patton PW, Rajon D A, Shah A P, Jokisch DW, Inglis B A and BolchWE 2002 Sitespecific variability in trabecular bone dosimetry: considerations of energy loss to cortical bone Med. Phys. 29 6-14
46. Patton P W, Jokisch D W, Rajon D A, Shah A P, Myers S L, Inglis B A and Bolch W E 2002 Skeletal dosimetry via NMR microscopy: investigations of sample reproducibility and signal source Health Phys. 82 316-26
47. Rajon D A, Jokisch D W, Patton P W, Shah A P and Bolch W E 2000 Voxel size effects in three-dimensional nuclear magnetic resonance microscopy performed for trabecular bone dosimetry Med. Phys. 27 2624-35
48. Bouchet L G and Bolch W E 1999 A three-dimensional transport model for determining absorbed fractions of energy for electrons within cortical bone J. Nucl. Med. 40 2115-24
49. Akabani G 1993 Absorbed dose calculations in Haversian canals for several betaemitting radionuclides J. Nucl. Med. 34 1361-6
50. Breems D A, Blokland E A, Neben S and Ploemacher R E 1994 Frequency analysis of human primitive haematopoietic stem cell subsets using a cobblestone area forming cell assay Leukemia 8 1095-104
51. Neben S, Anklesaria P, Greenberger J and Mauch P 1993 Quantitation of murine hematopoietic stem cells in vitro by limiting dilution analysis of cobblestone area formation on a clonal stromal cell line Exp. Hematol. 21 438-43
52. Bolch W E, Bouchet L G, Robertson J S, Wessels B W, Siegel J A, Howell R W, Erdi A K, Aydogan B, Costes S, Watson E E, Brill A B, Charkes N D, Fisher D R, Hays M T and Thomas S R 1999 MIRD pamphlet No 17: the dosimetry of nonuniform activity distributions-radionuclide S values at the voxel level. Medical Internal Radiation Dose Committee J. Nucl. Med. 40 11S-36S
53. DeNardo D A, DeNardo G L, O’Donnell R T, Lim S M, Shen S, Yuan A and DeNardo S J 1997 Imaging for improved prediction of myelotoxicity after radioimmunotherapy Cancer 80 2558-66
54. Lim S M, DeNardo G L, DeNardo D A, Shen S, Yuan A, O’Donnell R T and DeNardo S J 1997 Prediction of myelotoxicity using radiation doses to marrow from body, blood and marrow sources J. Nucl. Med. 38 1374-8
55. Eary J F, Krohn K A, Press O W, Durack L and Bernstein I D 1997 Importance of pre-treatment radiation absorbed dose estimation for radioimmunotherapy of non-Hodgkin’s lymphoma Nucl. Med. Biol. 24 635-8
56. Breitz H B, Fisher D R and Wessels B W 1998 Marrow toxicity and radiation absorbed dose estimates from rhenium-186-labeled monoclonal antibody J. Nucl. Med. 39 1746-51
57. 131I-labeled anti-CEA NP-4 IgG1: dependence on red marrow dosimetry and pretreatment. In Proceedings of the Sixth International Radiopharmaceutical Dosimetry Symposium Gatlinburg, TN, pp 113-25
58. Juweid M E, Zhang C H, Blumenthal R D, Hajjar G, Sharkey R M and Goldenberg D M 1999 Prediction of hematologic toxicity after radioimmunotherapy with (131)Ilabeled anticarcinoembryonic antigen monoclonal antibodies J. Nucl.Med. 40 1609-16
59. Emami B, Lyman J, Brown A, Coia L, Goitein M, Munzenrider J E, Shank B, Solin L J and Wesson M 1991 Tolerance of normal tissue to therapeutic irradiation Int. J. Radiat. Oncol. Biol. Phys. 21 109-22
60. Erdi A K, Erdi Y E, Yorke E D and Wessels B W 1996 Treatment planning for radioimmunotherapy Phys. Med. Biol. 41 2009-26
61. 131I-Lym-1 as a model Cancer 73 1038-48
62. Sgouros G, Barest G, Thekkumthala J, Chui C, Mohan R, Bigler R E and Zanzonico P B 1990 Treatment planning for internal radionuclide therapy: three-dimensional dosimetry for nonuniformly distributed radionuclides J. Nucl. Med. 31 1884-91
63. Akabani G, Hawkins W G, Eckblade M B and Leichner P K 1997 Patient-specific dosimetry using quantitative SPECT imaging and three-dimensional discrete Fourier transform convolution J. Nucl. Med. 38 308-14
64. Furhang E E, Chui C S and Sgouros G 1996 A Monte Carlo approach to patientspecific dosimetry Med. Phys. 23 1523-9
65. DeNardo G L, Lamborn K R, DeNardo S J, Goldstein D S, Dolber-Smith E G, Kroger L A, Larkin E C and Shen S 1995 Prognostic factors for radioimmunotherapy in patients with B-lymphocytic malignancies Cancer Res. 55 5893s-98s
66. Sgouros G, Jureidini IM, Scott AM, GrahamMC, Larson SMand Scheinberg D A 1996 Bone marrow dosimetry: regional variability of marrow-localizing antibody J. Nucl. Med. 37 695-8
67. Wessels B, Breitz H B, Meredith R, JuweidME, Pastor M, ColburnMand DeNardo G L 2000 Bone marrow dosimetry model adjustments based on age, gender and prior therapy J. Nucl. Med. 41 83P
68. 131I-G250 antibody therapy in patients with renal-cell carcinoma J. Nucl. Med. 38 252P
69. O’Donoghue J A, Baidoo N and Sgouros G 1998 Calculated red marrow absorbed dose predicts hematological toxicity in radioimmunotherapy J. Nucl. Med. 39 186P
70. Blumenthal R D, Lew W, Juweid M, Alisauskas R, Ying Z and Goldenberg DM 2000 Plasma FLT3-L levels predict bone marrow recovery from myelosuppressive therapy Cancer 88 333-43
71. Shields A F, Grierson J R, Dohmen B M, Machulla H J, Stayanoff J C, Lawhorn-Crews J M, Obradovich J E, Muzik O and Mangner T J 1998 Imaging proliferation in vivo with [F-18]FLT and positron emission tomography Nat. Med. 4 1334-6
72. Mauch P, Constine L, Greenberger J, Knospe W, Sullivan J, Liesveld J L and Deeg H J 1995 Hematopoietic stem cell compartment: acute and late effects of radiation therapy and chemotherapy Int. J. Radiat. Oncol. Biol. Phys. 31 1319-39
73. Koo K H, Dussault R, Kaplan P, Kim R, Ahn I O, Christopher J, Song H R and Wang G J 1998 Age-related marrow conversion in the proximal metaphysis of the femur: evaluation with T1-weighted MR imaging Radiology 206 745-8
74. Ballon D, Dyke J, Schwartz L H, Lis E, Schneider E, Lauto A and Jakubowski A 2000 Bone marrow segmentation in leukemia using diffusion and T2 weighted echo planar magnetic resonance imaging NMR Biomed. 13 321-28
75. Ballon D, Jakubowski A A, Tulipano P K, GrahamMC, Schneider E, Aghazadeh B, Chen Q S and Koutcher J A 1998 Quantitative assessment of bone marrow hematopoiesis using parametric magnetic resonance imaging Magn. Reson. Med. 39 789-800
76. Ballon D, Jakubowski A A, Graham M C, Schneider E and Koutcher J A 1996 Spatial mapping of the percentage cellularity in human bone marrow using magnetic resonance imaging Med. Phys. 23 243-50
77. Ballon D, Jakubowski A, Gabrilove J, Graham M C, Zakowski M, Sheridan C and Koutcher J A 1991 In vivo measurements of bone marrow cellularity using volumelocalized proton NMR spectroscopy Magn. Reson. Med. 19 85-95
78. Link T M, Majumdar S, Grampp S, Guglielmi G, van Kuijk C, Imhof H, Glueer C and Adams J E 1999 Imaging of trabecular bone structure in osteoporosis Eur. Radiol. 9 1781-8
79. Saito Y and Ortawara B S 2001 Development and evaluation of a real-time 3-dimensional CT (4D-CT) scanner. In 87th Annual Meeting of the Radiological Society of North America Chicago, IL
80. Nonomura Y, Yasumoto M, Yoshimura R, Haraguchi K, Ito S, Akashi T and Ohashi I 2001 Relationship between bone marrow cellularity and apparent diffusion coefficient J. Magn. Reson. Imaging 13 757-60
81. Schick F, Einsele H, Kost R, Duda S, Jung W I, Lutz O and Claussen C D 1994 Hematopoietic reconstitution after bone marrow transplantation: assessment with MR imaging and H-1 localized spectroscopy J. Magn. Reson. Imaging 4 71-8
82. Schick F, Einsele H, Weiss B, Forster J, Lutz O, Kanz L and Claussen C D 1996 Assessment of the composition of bone marrow prior to and following autologous BMT and PBSCT by magnetic resonance Ann. Hematol. 72 361-70