Nipah and Hendra virus nucleoproteins inhibit nuclear accumulation of signal transducer and activator of transcription 1 (STAT1) and STAT2 by interfering with their complex formation

Journal of Virology

Volumn 91, Issue 21, 2017, Pages

  Sugai, Akihiro ^a   Sato, Hiroki ^a   Takayama, Ikuyo ^a,b   Yoneda, Misako ^a   Kai, Chieko ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

Hendra virus; Henipavirus; Interferon; JAK STAT; Nipah virus; Nucleoprotein; Paramyxoviridae; STAT transcription factors

Indexed keywords

GAMMA INTERFERON; GLYCINE DEHYDROGENASE (DECARBOXYLATING); GUANINE NUCLEOTIDE BINDING PROTEIN; IMPORTIN ALPHA5; IMPORTIN BETA1; INTERFERON; NUCLEAR PROTEIN; RAN PROTEIN; STAT1 PROTEIN; STAT2 PROTEIN; UNCLASSIFIED DRUG; VIRUS NUCLEOPROTEIN; NUCLEOPROTEIN;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOKINE RESPONSE; CYTOPLASM; DOWN REGULATION; GENE; GENE REPRESSION; HENDRA VIRUS; HUMAN; HUMAN CELL; INTERFERON STIMULATED GENE; JAK-STAT SIGNALING; LUCIFERASE ASSAY; NIPAH VIRUS; NUCLEAR IMPORT; NUCLEOCYTOPLASMIC TRANSPORT; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; CELL NUCLEUS; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HENIPAVIRUS INFECTION; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; VIROLOGY;

CELL NUCLEUS; HEK293 CELLS; HELA CELLS; HENDRA VIRUS; HENIPAVIRUS INFECTIONS; HUMANS; IMMUNITY, INNATE; NIPAH VIRUS; NUCLEOPROTEINS; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; STAT2 TRANSCRIPTION FACTOR;

EID: 85031087111     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01136-17     Document Type: Article

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