메뉴 건너뛰기




Volumn 5, Issue 11, 2017, Pages 763-771

Heart Failure With Mid-Range (Borderline) Ejection Fraction: Clinical Implications and Future Directions

Author keywords

epidemiology; heart failure with borderline ejection fraction; heart failure with mid range ejection fraction; heart failure with preserved ejection fraction; HFbEF; HFmrEF; HFpEF; outcomes

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; ENKEPHALINASE INHIBITOR; IRBESARTAN; SACUBITRIL PLUS VALSARTAN; VALSARTAN;

EID: 85030857433     PISSN: 22131779     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchf.2017.06.013     Document Type: Review
Times cited : (146)

References (37)
  • 1
    • 0041356972 scopus 로고    scopus 로고
    • Natural history of asymptomatic left ventricular systolic dysfunction in the community
    • Wang, T.J., Evans, J.C., Benjamin, E.J., Levy, D., LeRoy, E.C., Vasan, R.S., Natural history of asymptomatic left ventricular systolic dysfunction in the community. Circulation 108 (2003), 977–982.
    • (2003) Circulation , vol.108 , pp. 977-982
    • Wang, T.J.1    Evans, J.C.2    Benjamin, E.J.3    Levy, D.4    LeRoy, E.C.5    Vasan, R.S.6
  • 2
    • 34547837711 scopus 로고    scopus 로고
    • Characteristics, treatments, and outcomes of patients with preserved systolic function hospitalized for heart failure: a report from the OPTIMIZE-HF Registry
    • Fonarow, G.C., Stough, W.G., Abraham, W.T., et al. Characteristics, treatments, and outcomes of patients with preserved systolic function hospitalized for heart failure: a report from the OPTIMIZE-HF Registry. J Am Coll Cardiol 50 (2007), 768–777.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 768-777
    • Fonarow, G.C.1    Stough, W.G.2    Abraham, W.T.3
  • 3
    • 84897487563 scopus 로고    scopus 로고
    • Developing therapies for heart failure with preserved ejection fraction: current state and future directions
    • Butler, J., Fonarow, G.C., Zile, M.R., et al. Developing therapies for heart failure with preserved ejection fraction: current state and future directions. J Am Coll Cardiol HF 2 (2014), 97–112.
    • (2014) J Am Coll Cardiol HF , vol.2 , pp. 97-112
    • Butler, J.1    Fonarow, G.C.2    Zile, M.R.3
  • 4
    • 41349112073 scopus 로고    scopus 로고
    • Comparison of clinical features and outcomes of patients hospitalized with heart failure and normal ejection fraction (> or =55%) versus those with mildly reduced (40% to 55%) and moderately to severely reduced (<40%) fractions
    • Sweitzer, N.K., Lopatin, M., Yancy, C.W., Mills, R.M., Stevenson, L.W., Comparison of clinical features and outcomes of patients hospitalized with heart failure and normal ejection fraction (> or =55%) versus those with mildly reduced (40% to 55%) and moderately to severely reduced (<40%) fractions. Am J Cardiol 101 (2008), 1151–1156.
    • (2008) Am J Cardiol , vol.101 , pp. 1151-1156
    • Sweitzer, N.K.1    Lopatin, M.2    Yancy, C.W.3    Mills, R.M.4    Stevenson, L.W.5
  • 5
    • 84884294190 scopus 로고    scopus 로고
    • 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
    • Yancy, C.W., Jessup, M., Bozkurt, B., et al. 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 62 (2013), e147–e239.
    • (2013) J Am Coll Cardiol , vol.62 , pp. e147-e239
    • Yancy, C.W.1    Jessup, M.2    Bozkurt, B.3
  • 6
    • 84980396108 scopus 로고    scopus 로고
    • 2016 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure: the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) developed with the special contribution of the Heart Failure Association (HFA) of the ESC
    • Ponikowski, P., Voors, A.A., Anker, S.D., et al. 2016 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure: the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J 37 (2016), 2129–2200.
    • (2016) Eur Heart J , vol.37 , pp. 2129-2200
    • Ponikowski, P.1    Voors, A.A.2    Anker, S.D.3
  • 7
    • 85017014567 scopus 로고    scopus 로고
    • Fussing over the middle child: heart failure with mid-range ejection fraction
    • Lam, C.S., Solomon, S.D., Fussing over the middle child: heart failure with mid-range ejection fraction. Circulation 135 (2017), 1279–1280.
    • (2017) Circulation , vol.135 , pp. 1279-1280
    • Lam, C.S.1    Solomon, S.D.2
  • 8
    • 84908367057 scopus 로고    scopus 로고
    • Outcomes in patients with heart failure with preserved, borderline, and reduced ejection fraction in the Medicare population
    • Cheng, R.K., Cox, M., Neely, M.L., et al. Outcomes in patients with heart failure with preserved, borderline, and reduced ejection fraction in the Medicare population. Am Heart J 168 (2014), 721–730.
    • (2014) Am Heart J , vol.168 , pp. 721-730
    • Cheng, R.K.1    Cox, M.2    Neely, M.L.3
  • 9
    • 85029007717 scopus 로고    scopus 로고
    • Heart disease and stroke statistics—2017 update: a report from the American Heart Association
    • Benjamin, E.J., Blaha, M.J., Chiuve, S.E., et al. Heart disease and stroke statistics—2017 update: a report from the American Heart Association. Circulation 135 (2017), e146–e603.
    • (2017) Circulation , vol.135 , pp. e146-e603
    • Benjamin, E.J.1    Blaha, M.J.2    Chiuve, S.E.3
  • 10
    • 84977147320 scopus 로고    scopus 로고
    • Precipitating clinical factors, heart failure characterization, and outcomes in patients hospitalized with heart failure with reduced, borderline, and preserved ejection fraction
    • Kapoor, J.R., Kapoor, R., Ju, C., et al. Precipitating clinical factors, heart failure characterization, and outcomes in patients hospitalized with heart failure with reduced, borderline, and preserved ejection fraction. J Am Coll Cardiol HF 4 (2016), 464–472.
    • (2016) J Am Coll Cardiol HF , vol.4 , pp. 464-472
    • Kapoor, J.R.1    Kapoor, R.2    Ju, C.3
  • 11
    • 85017364572 scopus 로고    scopus 로고
    • Characterization of heart failure patients with mid-range left ventricular ejection fraction—a report from the CHART-2 Study
    • [E-pub ahead of print]
    • Tsuji, K., Sakata, Y., Nochioka, K., et al. Characterization of heart failure patients with mid-range left ventricular ejection fraction—a report from the CHART-2 Study. Eur J Heart Fail, 2017 Mar 31 [E-pub ahead of print].
    • (2017) Eur J Heart Fail
    • Tsuji, K.1    Sakata, Y.2    Nochioka, K.3
  • 12
    • 84974699024 scopus 로고    scopus 로고
    • Magnitude of and prognostic factors associated with 1-year mortality after hospital discharge for acute decompensated heart failure based on ejection fraction findings
    • Coles, A.H., Tisminetzky, M., Yarzebski, J., et al. Magnitude of and prognostic factors associated with 1-year mortality after hospital discharge for acute decompensated heart failure based on ejection fraction findings. J Am Heart Assoc, 4, 2015, e002303.
    • (2015) J Am Heart Assoc , vol.4 , pp. e002303
    • Coles, A.H.1    Tisminetzky, M.2    Yarzebski, J.3
  • 13
    • 84863614614 scopus 로고    scopus 로고
    • Trends in patients hospitalized with heart failure and preserved left ventricular ejection fraction: prevalence, therapies, and outcomes
    • Steinberg, B.A., Zhao, X., Heidenreich, P.A., et al. Trends in patients hospitalized with heart failure and preserved left ventricular ejection fraction: prevalence, therapies, and outcomes. Circulation 126 (2012), 65–75.
    • (2012) Circulation , vol.126 , pp. 65-75
    • Steinberg, B.A.1    Zhao, X.2    Heidenreich, P.A.3
  • 14
    • 85015257096 scopus 로고    scopus 로고
    • Heart failure with mid-range ejection fraction: a distinct clinical entity? Insights from the Trial of Intensified Versus Standard Medical Therapy in Elderly Patients With Congestive Heart Failure (TIME-CHF)
    • [E-pub ahead of print]
    • Rickenbacher, P., Kaufmann, B.A., Maeder, M.T., et al. Heart failure with mid-range ejection fraction: a distinct clinical entity? Insights from the Trial of Intensified Versus Standard Medical Therapy in Elderly Patients With Congestive Heart Failure (TIME-CHF). Eur J Heart Fail, 2017 Mar 15 [E-pub ahead of print].
    • (2017) Eur J Heart Fail
    • Rickenbacher, P.1    Kaufmann, B.A.2    Maeder, M.T.3
  • 15
    • 67649497912 scopus 로고    scopus 로고
    • Relation of disease pathogenesis and risk factors to heart failure with preserved or reduced ejection fraction: insights from the Framingham Heart Study of the National Heart, Lung, and Blood Institute
    • Lee, D.S., Gona, P., Vasan, R.S., et al. Relation of disease pathogenesis and risk factors to heart failure with preserved or reduced ejection fraction: insights from the Framingham Heart Study of the National Heart, Lung, and Blood Institute. Circulation 119 (2009), 3070–3077.
    • (2009) Circulation , vol.119 , pp. 3070-3077
    • Lee, D.S.1    Gona, P.2    Vasan, R.S.3
  • 16
    • 79955759374 scopus 로고    scopus 로고
    • Diastolic and systolic heart failure are distinct phenotypes within the heart failure spectrum
    • discussion 2014
    • Borlaug, B.A., Redfield, M.M., Diastolic and systolic heart failure are distinct phenotypes within the heart failure spectrum. Circulation 123 (2011), 2006–2013 discussion 2014.
    • (2011) Circulation , vol.123 , pp. 2006-2013
    • Borlaug, B.A.1    Redfield, M.M.2
  • 17
    • 33746033433 scopus 로고    scopus 로고
    • Outcome of heart failure with preserved ejection fraction in a population-based study
    • Bhatia, R.S., Tu, J.V., Lee, D.S., et al. Outcome of heart failure with preserved ejection fraction in a population-based study. N Engl J Med 355 (2006), 260–269.
    • (2006) N Engl J Med , vol.355 , pp. 260-269
    • Bhatia, R.S.1    Tu, J.V.2    Lee, D.S.3
  • 18
    • 84880118241 scopus 로고    scopus 로고
    • The survival of patients with heart failure with preserved or reduced left ventricular ejection fraction: an individual patient data meta-analysis
    • Meta-analysis Global Group in Chronic Heart Failure (MAGGIC). The survival of patients with heart failure with preserved or reduced left ventricular ejection fraction: an individual patient data meta-analysis. Eur Heart J 33 (2012), 1750–1757.
    • (2012) Eur Heart J , vol.33 , pp. 1750-1757
  • 19
    • 33644878739 scopus 로고    scopus 로고
    • Influence of ejection fraction on cardiovascular outcomes in a broad spectrum of heart failure patients
    • Solomon, S.D., Anavekar, N., Skali, H., et al. Influence of ejection fraction on cardiovascular outcomes in a broad spectrum of heart failure patients. Circulation 112 (2005), 3738–3744.
    • (2005) Circulation , vol.112 , pp. 3738-3744
    • Solomon, S.D.1    Anavekar, N.2    Skali, H.3
  • 20
    • 84877986173 scopus 로고    scopus 로고
    • Predicting survival in heart failure: a risk score based on 39 372 patients from 30 studies
    • Pocock, S.J., Ariti, C.A., McMurray, J.J., et al. Predicting survival in heart failure: a risk score based on 39 372 patients from 30 studies. Eur Heart J 34 (2013), 1404–1413.
    • (2013) Eur Heart J , vol.34 , pp. 1404-1413
    • Pocock, S.J.1    Ariti, C.A.2    McMurray, J.J.3
  • 21
    • 85016811660 scopus 로고    scopus 로고
    • Associations with and prognostic impact of chronic kidney disease in heart failure with preserved, mid-range, and reduced ejection fraction
    • [E-pub ahead of print]
    • Löfman, I., Szummer, K., Dahlström, U., Jernberg, T., Lund, L.H., Associations with and prognostic impact of chronic kidney disease in heart failure with preserved, mid-range, and reduced ejection fraction. Eur J Heart Fail, 2017 Mar 29 [E-pub ahead of print].
    • (2017) Eur J Heart Fail
    • Löfman, I.1    Szummer, K.2    Dahlström, U.3    Jernberg, T.4    Lund, L.H.5
  • 22
    • 84926143863 scopus 로고    scopus 로고
    • Long-term survival for patients with acute decompensated heart failure according to ejection fraction findings
    • Coles, A.H., Fisher, K., Darling, C., et al. Long-term survival for patients with acute decompensated heart failure according to ejection fraction findings. Am J Cardiol 114 (2014), 862–868.
    • (2014) Am J Cardiol , vol.114 , pp. 862-868
    • Coles, A.H.1    Fisher, K.2    Darling, C.3
  • 23
    • 84898713808 scopus 로고    scopus 로고
    • Spironolactone for heart failure with preserved ejection fraction
    • Pitt, B., Pfeffer, M.A., Assmann, S.F., et al. Spironolactone for heart failure with preserved ejection fraction. N Engl J Med 370 (2014), 1383–1392.
    • (2014) N Engl J Med , vol.370 , pp. 1383-1392
    • Pitt, B.1    Pfeffer, M.A.2    Assmann, S.F.3
  • 24
    • 84960104469 scopus 로고    scopus 로고
    • Influence of ejection fraction on outcomes and efficacy of spironolactone in patients with heart failure with preserved ejection fraction
    • Solomon, S.D., Claggett, B., Lewis, E.F., et al. Influence of ejection fraction on outcomes and efficacy of spironolactone in patients with heart failure with preserved ejection fraction. Eur Heart J 37 (2016), 455–462.
    • (2016) Eur Heart J , vol.37 , pp. 455-462
    • Solomon, S.D.1    Claggett, B.2    Lewis, E.F.3
  • 25
    • 85030124629 scopus 로고    scopus 로고
    • 2017 ACC/AHA/HFSA focused update of the 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America
    • [E-pub ahead of print]
    • Yancy, C.W., Jessup, M., Bozkurt, B., et al. 2017 ACC/AHA/HFSA focused update of the 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America. J Am Coll Cardiol, 2017 Apr 21 [E-pub ahead of print].
    • (2017) J Am Coll Cardiol
    • Yancy, C.W.1    Jessup, M.2    Bozkurt, B.3
  • 26
    • 0041408234 scopus 로고    scopus 로고
    • Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial
    • Yusuf, S., Pfeffer, M.A., Swedberg, K., et al. Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial. Lancet Lond Engl 362 (2003), 777–781.
    • (2003) Lancet Lond Engl , vol.362 , pp. 777-781
    • Yusuf, S.1    Pfeffer, M.A.2    Swedberg, K.3
  • 27
    • 57349142933 scopus 로고    scopus 로고
    • Irbesartan in patients with heart failure and preserved ejection fraction
    • Massie, B.M., Carson, P.E., McMurray, J.J., et al. Irbesartan in patients with heart failure and preserved ejection fraction. N Engl J Med 359 (2008), 2456–2467.
    • (2008) N Engl J Med , vol.359 , pp. 2456-2467
    • Massie, B.M.1    Carson, P.E.2    McMurray, J.J.3
  • 28
    • 58149097941 scopus 로고    scopus 로고
    • Clinical effectiveness of beta-blockers in heart failure: findings from the OPTIMIZE-HF (Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure) Registry
    • Hernandez, A.F., Hammill, B.G., O'Connor, C.M., Schulman, K.A., Curtis, L.H., Fonarow, G.C., Clinical effectiveness of beta-blockers in heart failure: findings from the OPTIMIZE-HF (Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure) Registry. J Am Coll Cardiol 53 (2009), 184–192.
    • (2009) J Am Coll Cardiol , vol.53 , pp. 184-192
    • Hernandez, A.F.1    Hammill, B.G.2    O'Connor, C.M.3    Schulman, K.A.4    Curtis, L.H.5    Fonarow, G.C.6
  • 29
    • 84908060979 scopus 로고    scopus 로고
    • Rationale and design of the GUIDE-IT study: guiding evidence based therapy using biomarker intensified treatment in heart failure
    • Felker, G.M., Ahmad, T., Anstrom, K.J., et al. Rationale and design of the GUIDE-IT study: guiding evidence based therapy using biomarker intensified treatment in heart failure. J Am Coll Cardiol HF 2 (2014), 457–465.
    • (2014) J Am Coll Cardiol HF , vol.2 , pp. 457-465
    • Felker, G.M.1    Ahmad, T.2    Anstrom, K.J.3
  • 30
    • 84873429479 scopus 로고    scopus 로고
    • Longitudinal changes in ejection fraction in heart failure patients with preserved and reduced ejection fraction
    • Dunlay, S.M., Roger, V.L., Weston, S.A., Jiang, R., Redfield, M.M., Longitudinal changes in ejection fraction in heart failure patients with preserved and reduced ejection fraction. Circ Heart Fail 5 (2012), 720–726.
    • (2012) Circ Heart Fail , vol.5 , pp. 720-726
    • Dunlay, S.M.1    Roger, V.L.2    Weston, S.A.3    Jiang, R.4    Redfield, M.M.5
  • 31
    • 84857857236 scopus 로고    scopus 로고
    • Impact of noncardiac comorbidities on morbidity and mortality in a predominantly male population with heart failure and preserved versus reduced ejection fraction
    • Ather, S., Chan, W., Bozkurt, B., et al. Impact of noncardiac comorbidities on morbidity and mortality in a predominantly male population with heart failure and preserved versus reduced ejection fraction. J Am Coll Cardiol 59 (2012), 998–1005.
    • (2012) J Am Coll Cardiol , vol.59 , pp. 998-1005
    • Ather, S.1    Chan, W.2    Bozkurt, B.3
  • 32
    • 84944800184 scopus 로고    scopus 로고
    • Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes
    • Zinman, B., Wanner, C., Lachin, J.M., et al. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N Engl J Med 373 (2015), 2117–2128.
    • (2015) N Engl J Med , vol.373 , pp. 2117-2128
    • Zinman, B.1    Wanner, C.2    Lachin, J.M.3
  • 34
    • 84864182823 scopus 로고    scopus 로고
    • Assessment of myocardial scarring improves risk stratification in patients evaluated for cardiac defibrillator implantation
    • Klem, I., Weinsaft, J.W., Bahnson, T.D., et al. Assessment of myocardial scarring improves risk stratification in patients evaluated for cardiac defibrillator implantation. J Am Coll Cardiol 60 (2012), 408–420.
    • (2012) J Am Coll Cardiol , vol.60 , pp. 408-420
    • Klem, I.1    Weinsaft, J.W.2    Bahnson, T.D.3
  • 35
    • 85018833039 scopus 로고    scopus 로고
    • Association between mid-wall late gadolinium enhancement and sudden cardiac death in patients with dilated cardiomyopathy and mild and moderate left ventricular systolic dysfunction
    • Halliday, B., Gulati, A., Ali, A., et al. Association between mid-wall late gadolinium enhancement and sudden cardiac death in patients with dilated cardiomyopathy and mild and moderate left ventricular systolic dysfunction. Circulation 135 (2017), 2106–2115.
    • (2017) Circulation , vol.135 , pp. 2106-2115
    • Halliday, B.1    Gulati, A.2    Ali, A.3
  • 36
    • 84925765047 scopus 로고    scopus 로고
    • Wireless pulmonary artery pressure monitoring guides management to reduce decompensation in heart failure with preserved ejection fraction
    • Adamson, P.B., Abraham, W.T., Bourge, R.C., et al. Wireless pulmonary artery pressure monitoring guides management to reduce decompensation in heart failure with preserved ejection fraction. Circ Heart Fail 7 (2014), 935–944.
    • (2014) Circ Heart Fail , vol.7 , pp. 935-944
    • Adamson, P.B.1    Abraham, W.T.2    Bourge, R.C.3
  • 37
    • 85020017334 scopus 로고    scopus 로고
    • Role of biomarkers for the prevention, assessment, and management of heart failure: a scientific statement from the American Heart Association
    • Chow, S.L., Maisel, A.S., Anand, I., et al. Role of biomarkers for the prevention, assessment, and management of heart failure: a scientific statement from the American Heart Association. Circulation 135 (2017), e1054–e1091.
    • (2017) Circulation , vol.135 , pp. e1054-e1091
    • Chow, S.L.1    Maisel, A.S.2    Anand, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.