Diagnostic performance of high sensitivity compared with contemporary cardiac troponin I for the diagnosis of acute myocardial infarction

Clinical Chemistry

Volumn 63, Issue 10, 2017, Pages 1594-1604

  Sandoval, Yader ^a   Smith, Stephen W ^b,c   Thordsen, Sarah E ^a   Bruen, Charles A ^b   Carlson, Michelle D ^a   Dodd, Kenneth W ^b   Driver, Brian E ^b   Jacoby, Katherine ^b   Johnson, Benjamin K ^a   Love, Sara A ^b,d   Moore, Johanna C ^b   Sexter, Anne ^e   Schulz, Karen ^e   Scott, Nathaniel L ^b   Nicholson, Jennifer ^b   Apple, Fred S ^b,d  

^a MINNEAPOLIS HEART INSTITUTE FOUNDATION   (United States)

^b HENNEPIN COUNTY MEDICAL CENTER   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

^d UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^e MINNEAPOLIS MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH SENSITIVITY CARDIAC TROPONIN I; TROPONIN I; UNCLASSIFIED DRUG; BIOLOGICAL MARKER;

ACUTE HEART INFARCTION; ARTICLE; CLINICAL OUTCOME; CLINICAL PRACTICE; DELTA RHYTHM; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; ELECTROCARDIOGRAM; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PATIENT SAFETY; PREDICTIVE VALUE; SENSITIVITY AND SPECIFICITY; UNITED STATES; CLINICAL TRIAL; LABORATORY TECHNIQUE; MYOCARDIAL INFARCTION; PROGNOSIS;

BIOMARKERS; CLINICAL LABORATORY TECHNIQUES; FEMALE; HUMANS; MALE; MYOCARDIAL INFARCTION; PROGNOSIS; SENSITIVITY AND SPECIFICITY; TROPONIN I;

EID: 85030772648     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2017.272930     Document Type: Article

References (20)

1. Thygesen K, Alpert JS, Jaffe AS, Simoons ML, Chaitman BR, White HD, et al. Third universal definition of myocardial infarction. J AmColl Cardiol 2012; 60: 1581-98.
2. Apple FS, Sandoval Y, Jaffe AS, Ordonez-Llanos, IFCC Task Force on Clinical Applications of Cardiac Bio- Markers. Cardiac troponin assays: Guide to understanding analytical characteristics and their impact on clinical care. Clin Chem 2017; 63: 73-81.
3. Apple FS, Jaffe AS, Collinson P, Mockel M, Ordonez- Llanos J, Lindahl B, et al. IFCC educational materials on selected analytical and clinical applications of highsensitivity cardiac troponin assays. Clin Biochem 2015; 48: 201-3.
4. Apple FS, Collinson PO, IFCC Task Force on Clinical Applications of Cardiac Biomarkers. Analytical characteristics of high-sensitivity cardiac troponin assays. Clin Chem 2012; 58: 54-61.
5. Amsterdam EA, Wenger NK, Brindis RG, Casey DE Jr., Ganiats TG, Holmes DR, Jr., et al. 2014 AHA/ACC guideline for the management of patients with non- ST-elevation acute coronary syndromes: Executive summary: A report of the America College of Cardiology/ American Heart Association Task Force on Practice Guidelines. Circulation 2014; 130: 2354-94.
6. Sandoval Y, Apple FS. The global need to define normality: The 99th percentile value of cardiac troponin. Clin Chem 2014; 60: 455-62.
7. Sandoval Y, Smith SW, Apple FS. Present and future of cardiac troponin in clinical practice: A paradigm shift to high-sensitivity assays. Am J Med 2016; 129: 354-65.
8. Roffis M, Patrono C, Collet JP, Mueller C, Valgimigli M, Andreotti F, et al. 2015 ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC). Eur Heart J 2016; 37: 267-315.
9. Morrow DA. Clinicians guide to early rule-out strategies with high-sensitivity cardiac troponin. Circulation 2017; 135: 1612-6.
10. Sandoval Y, Smith SW, Schulz KM, MurakamiMM,Love SA, Nicholson J, Apple FS. Diagnosis of type 1 and type 2 myocardial infarction using a high-sensitivity cardiac troponin I assay with sex-specific 99th percentiles based on the third universal definition of myocardial infarction classification system. Clin Chem 2015; 61: 657-63.
11. Love SA, Sandoval Y, Smith SW, Nicholson J, Cao J, Ler R, et al. Incidence of undetectable, measurable, and increased cardiac troponin I concentrations above the 99th percentile using a high-sensitivity vs. a contemporary assay in patients presenting to the emergency department. Clin Chem 2016; 62: 1115-9.
12. Sandoval Y, Smith SW, Shah AS, Anand A, Chapman AR, Love SA, et al. Rapid rule-out of acute myocardial injury using a single high-sensitivity cardiac troponin I measurement. Clin Chem 2017; 63: 369-76.
13. Than M, Herbert M, Flaws D, Cullen L, Hess E, Hollander JE, et al. What is an acceptable risk of major adverse cardiac event in chest pain patients soon after discharge from the emergency department? a clinical survey. Int J Cardiol 2013; 166: 752-4.
14. Pickering JW, Greenslade JH, Cullen L, Flaws D, Parsonage W, George P, et al. Validation of presentation and 3 h high-sensitivity troponin to rule-in and rule-out acute myocardial infarction. Heart 2016; 102: 1270-8.
15. Sandoval Y, Thygesen K. Myocardial infarction type 2 and myocardial injury. Clin Chem 2017; 63: 101-7.
16. Reichlin T, Irfan A, Twerenbold R, Reiter M, Hochholzer W, Burkhalter H, et al. Utility of absolute and relative changes in cardiac troponin concentrations in the early diagnosis of acute myocardial infarction. Circulation 2011; 124: 136-45.
17. Mueller M, Biener M, Vafaie M, Doerr S, Keller T, Blankenberg S, et al. Absolute and relative kinetic changes of high-sensitivity cardiac troponin T in acute coronary syndrome in patients with increased troponin in the absence of acute coronary syndrome. Clin Chem 2012; 58: 209-18.
18. Apple FS, Smith SW, Pearce LA, Murakami MM. Delta changes for optimizing clinical specificity and 60-day risk of adverse events in patients presenting with symptoms suggestive of acute coronary syndrome utilizing the ADVIA Centaur TnI-Ultra assay. Clin Biochem 2012; 45: 711-3.
19. Reichlin T, Twerenbold R, Reiter M, Steuer S, Bassetti S, Balmelli C, et al. Introduction of high-sensitivity troponin assays: Impact on myocardial infarction incidence and prognosis. Am J Med 2012; 125: 1205-13.
20. Sandoval Y, Smith SW, Thordsen SE, Bruen CA, Carlson MD, Dodd KW, et al. Type 1 and 2 myocardial infarction and myocardial injury: Clinical transition to highsensitivity cardiac troponin I. [Epub ahead of print] Am J Med July 21, 2017 as doi: Http: //dx.doi.org/ 10.1016/j.amjmed.2017.05.049.