메뉴 건너뛰기




Volumn 20, Issue 3, 2017, Pages 352-360

Lutetium-177-labelled anti-prostate-specific membrane antigen antibody and ligands for the treatment of metastatic castrate-resistant prostate cancer: A systematic review and meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

DKZ LU 177; DOTAGA (I-Y)FK LU 177; MONOCLONAL ANTIBODY J591; MONOCLONAL ANTIBODY J591 LU 177; PROSTATE SPECIFIC ANTIGEN; PROSTATE SPECIFIC MEMBRANE ANTIGEN; RADIOLIGAND; UNCLASSIFIED DRUG; GLUTAMATE CARBOXYPEPTIDASE II; GLUTAMATE CARBOXYPEPTIDASE II, HUMAN; KALLIKREIN; KALLIKREIN-RELATED PEPTIDASE 3, HUMAN; LIGAND; LUTETIUM; LUTETIUM-177; MEMBRANE ANTIGEN; RADIOISOTOPE; RADIOPHARMACEUTICAL AGENT;

EID: 85030756743     PISSN: 13657852     EISSN: 14765608     Source Type: Journal    
DOI: 10.1038/pcan.2017.23     Document Type: Article
Times cited : (71)

References (37)
  • 1
    • 85014090415 scopus 로고    scopus 로고
    • EAU-ESTROSIOG guidelines on prostate cancer Part II: Treatment of relapsing, metastatic and castration-resistant prostate cancer
    • Conford P, Bellmunt J, Bolla M, Briers E, De Santis M, Gross T et al. EAU-ESTROSIOG guidelines on prostate cancer. Part II: treatment of relapsing, metastatic and castration-resistant prostate cancer. Eur Urol 2017; 71: 630-642.
    • (2017) Eur Urol , vol.71 , pp. 630-642
    • Conford, P.1    Bellmunt, J.2    Bolla, M.3    Briers, E.4    De Santis, M.5    Gross, T.6
  • 2
    • 84991320867 scopus 로고    scopus 로고
    • PSMA-based radioligand therapy for metastatic castration-resistant prostate cancer: The bad berka experience 2013
    • Kulkarni HR, Singh A, Schuchardt C, Niepsch K, Sayeg M, Leshch Y et al. PSMA-based radioligand therapy for metastatic castration-resistant prostate cancer: the bad berka experience 2013. J Nucl Med 2016; 57: 97S-104S.
    • (2016) J Nucl Med , vol.57 , pp. 97S-104S
    • Kulkarni, H.R.1    Singh, A.2    Schuchardt, C.3    Niepsch, K.4    Sayeg, M.5    Leshch, Y.6
  • 3
    • 84978426205 scopus 로고    scopus 로고
    • 177Lulabeled prostate-specific membrane antigen radioligand therapy of metastatic castration-resistant prostate cancer: Safety and efficacy
    • Baum RP, Kulkarni HR, Schuchardt C, Singh A, Wirtz M, Wiessalla S et al. 177Lulabeled prostate-specific membrane antigen radioligand therapy of metastatic castration-resistant prostate cancer: safety and efficacy. J Nucl Med 2016; 57: 1006-1013.
    • (2016) J Nucl Med , vol.57 , pp. 1006-1013
    • Baum, R.P.1    Kulkarni, H.R.2    Schuchardt, C.3    Singh, A.4    Wirtz, M.5    Wiessalla, S.6
  • 4
    • 0032530135 scopus 로고    scopus 로고
    • Constitutive and antibody-induced internalization of prostate-specific membrane antigen
    • Liu H, Rajasekaran AK, Moy P, Xia Y, Kim S, Navarro V et al. Constitutive and antibody-induced internalization of prostate-specific membrane antigen. Cancer Res 1998; 58: 4055-4060.
    • (1998) Cancer Res , vol.58 , pp. 4055-4060
    • Liu, H.1    Rajasekaran, A.K.2    Moy, P.3    Xia, Y.4    Kim, S.5    Navarro, V.6
  • 5
    • 0030866116 scopus 로고    scopus 로고
    • Monoclonal antibodies to the extracellular domain of prostate-specific membrane antigen also react with tumour vascular endothelium
    • Liu H, Moy P, Kim S, Xia Y, Rajasekaran A, Navarro V et al. Monoclonal antibodies to the extracellular domain of prostate-specific membrane antigen also react with tumour vascular endothelium. Cancer Res 1997; 57: 3629-3634.
    • (1997) Cancer Res , vol.57 , pp. 3629-3634
    • Liu, H.1    Moy, P.2    Kim, S.3    Xia, Y.4    Rajasekaran, A.5    Navarro, V.6
  • 6
    • 84949808103 scopus 로고    scopus 로고
    • Radioimmunotherapy of metastatic prostate cancer with 177Lu-DOTA-huJ591 anti-prostate specific membrane antigen specific monoclonal antibody
    • Vallabhajosula S, Nikolopoulou A, Jhanwar YS, Kaur G, Tagawa ST, Nanus DM et al. Radioimmunotherapy of metastatic prostate cancer with 177Lu-DOTA-huJ591 anti-prostate specific membrane antigen specific monoclonal antibody. Curr Radiopharm 2016; 9: 44-53.
    • (2016) Curr Radiopharm , vol.9 , pp. 44-53
    • Vallabhajosula, S.1    Nikolopoulou, A.2    Jhanwar, Y.S.3    Kaur, G.4    Tagawa, S.T.5    Nanus, D.M.6
  • 7
    • 0141919750 scopus 로고    scopus 로고
    • Targeting metastatic prostate cancer with radiolabeled monoclonal antibody J591 to the extracellular domain of prostate specific membrane antigen
    • Bander NH, Trabulsi EJ, Kostakoglu L, Yao D, Vallabhajosula S, Smith-Jones P et al. Targeting metastatic prostate cancer with radiolabeled monoclonal antibody J591 to the extracellular domain of prostate specific membrane antigen. J Urol 2003; 170: 1717-1721.
    • (2003) J Urol , vol.170 , pp. 1717-1721
    • Bander, N.H.1    Trabulsi, E.J.2    Kostakoglu, L.3    Yao, D.4    Vallabhajosula, S.5    Smith-Jones, P.6
  • 8
    • 67249105432 scopus 로고    scopus 로고
    • Design, synthesis, and pre-clinical evaluation of prostate specific membrane antigen targeted 99mTc-radioimmaging agents
    • Kularatne SA, Zhou Z, Yang J, Post CB, Low PS. Design, synthesis, and pre-clinical evaluation of prostate specific membrane antigen targeted 99mTc-radioimmaging agents. Mol Pharm 2009; 6: 790-800.
    • (2009) Mol Pharm , vol.6 , pp. 790-800
    • Kularatne, S.A.1    Zhou, Z.2    Yang, J.3    Post, C.B.4    Low, P.S.5
  • 9
    • 77956444662 scopus 로고    scopus 로고
    • A remote arene-bidning site on prostate specific membrane antigen revealed by antibody-recruiting small molecules
    • Zhang AX, Murelli RP, Barinka C, Michel J, Cocleaza A, Jorgensen WL et al. A remote arene-bidning site on prostate specific membrane antigen revealed by antibody-recruiting small molecules. J Am Chem Soc 2010; 132: 12711-12716.
    • (2010) J Am Chem Soc , vol.132 , pp. 12711-12716
    • Zhang, A.X.1    Murelli, R.P.2    Barinka, C.3    Michel, J.4    Cocleaza, A.5    Jorgensen, W.L.6
  • 10
    • 84938833007 scopus 로고    scopus 로고
    • 68Ga- and 177Lu-labeled PSMA I&T: Optimization of a PSMA targeted theranostic concept and first proof of concept human studies
    • Weineisen M, Schottelius M, Simecek J, Baum RP, Yildiz A, Beykan S et al. 68Ga- and 177Lu-labeled PSMA I&T: optimization of a PSMA targeted theranostic concept and first proof of concept human studies. J Nucl Med 2015; 56: 1169-1176.
    • (2015) J Nucl Med , vol.56 , pp. 1169-1176
    • Weineisen, M.1    Schottelius, M.2    Simecek, J.3    Baum, R.P.4    Yildiz, A.5    Beykan, S.6
  • 11
    • 70149094319 scopus 로고    scopus 로고
    • Pre-clinical evaluation of novel glutamate-urea-lysine analogues that target prostate-specific membrane antigen as molecular imaging pharmaceuticals for prostate cancer
    • Hillier SM, Maresca KP, Femia FJ, Marquis JC, Foss CA, Nguyen N et al. Pre-clinical evaluation of novel glutamate-urea-lysine analogues that target prostate-specific membrane antigen as molecular imaging pharmaceuticals for prostate cancer. Cancer Res 2009; 69: 6932-6940.
    • (2009) Cancer Res , vol.69 , pp. 6932-6940
    • Hillier, S.M.1    Maresca, K.P.2    Femia, F.J.3    Marquis, J.C.4    Foss, C.A.5    Nguyen, N.6
  • 12
    • 84930364730 scopus 로고    scopus 로고
    • Preclinical evaluation of tailor-made DOTA-conjugated PSMA inhibitor with optimized linker moiety for imaging and endoradiotherapy of prostate cancer
    • Benesova M, Schafer M, Bauder-Wust U, Afshar-Oromieh A, Kratochwil C, Mier W et al. Preclinical evaluation of tailor-made DOTA-conjugated PSMA inhibitor with optimized linker moiety for imaging and endoradiotherapy of prostate cancer. J Nucl Med 2015; 56: 914-920.
    • (2015) J Nucl Med , vol.56 , pp. 914-920
    • Benesova, M.1    Schafer, M.2    Bauder-Wust, U.3    Afshar-Oromieh, A.4    Kratochwil, C.5    Mier, W.6
  • 13
    • 22044451179 scopus 로고    scopus 로고
    • Phase i trial of 177lutetium labeled J591, a monoclonal antibody to prostatespecific membrane antigen, in patients with androgen-independent prostate cancer
    • Bander NH, Milowsky MI, Nanus DM, Kostakoglu L, Vallabhajosula S, Goldsmith SJ. Phase I trial of 177lutetium labeled J591, a monoclonal antibody to prostatespecific membrane antigen, in patients with androgen-independent prostate cancer. J Clin Oncol 2005; 23: 4591-4601.
    • (2005) J Clin Oncol , vol.23 , pp. 4591-4601
    • Bander, N.H.1    Milowsky, M.I.2    Nanus, D.M.3    Kostakoglu, L.4    Vallabhajosula, S.5    Goldsmith, S.J.6
  • 14
    • 85030787231 scopus 로고    scopus 로고
    • Phase II study of Lutetium-177-labelled anti-prostate-specific membrane antigen monoclonal antibody J591 for metastatic castration-resistant prostate cancer
    • Tagawa ST, Milowsky M, Morris M, Vallabhajosula S, Christos P, Akhtar NH et al. Phase II study of Lutetium-177-labelled anti-prostate-specific membrane antigen monoclonal antibody J591 for metastatic castration-resistant prostate cancer. Clin Cancer Res 2013; 46: 220-231.
    • (2013) Clin Cancer Res , vol.46 , pp. 220-231
    • Tagawa, S.T.1    Milowsky, M.2    Morris, M.3    Vallabhajosula, S.4    Christos, P.5    Akhtar, N.H.6
  • 15
    • 84934918549 scopus 로고    scopus 로고
    • Early side effects and first results of radioligand therapy with (177)Lu-DKFZ-617 PSMA of castrate-resistant metastatic prostate cancer: A two-centre study
    • Ahmadzadehfar H, Rahbar K, Kurpig S, Bogemann M, Claesener M, Eppard E et al. Early side effects and first results of radioligand therapy with (177)Lu-DKFZ-617 PSMA of castrate-resistant metastatic prostate cancer: a two-centre study. EJNMMI Res 2015; 5: 1-8.
    • (2015) EJNMMI Res , vol.5 , pp. 1-8
    • Ahmadzadehfar, H.1    Rahbar, K.2    Kurpig, S.3    Bogemann, M.4    Claesener, M.5    Eppard, E.6
  • 16
    • 84979659039 scopus 로고    scopus 로고
    • Systemic radioligand therapy with 177Lu labeled prostate specific membrane for imaging and therapy in patients with metastatic castration-resistant prostate cancer
    • Heck MM, Retz M, D'Alessandria C, Rauscher I, Scheidhauer K, Maurer T et al. Systemic radioligand therapy with 177Lu labeled prostate specific membrane for imaging and therapy in patients with metastatic castration-resistant prostate cancer. J Urol 2016; 196: 382-391.
    • (2016) J Urol , vol.196 , pp. 382-391
    • Heck, M.M.1    Retz, M.2    D'Alessandria, C.3    Rauscher, I.4    Scheidhauer, K.5    Maurer, T.6
  • 17
    • 85009751119 scopus 로고    scopus 로고
    • Preliminary experience with dosimetry, response and patient reported outcome after 177Lu-PSMA-617 therapy for metastatic castration-resistant prostate cancer
    • Fendler WP, Reinhardt S, Ilhan H, Delker A, Boning G, Gildehaus FJ et al. Preliminary experience with dosimetry, response and patient reported outcome after 177Lu-PSMA-617 therapy for metastatic castration-resistant prostate cancer. Oncotarget 2016; 8: 3581-3590.
    • (2016) Oncotarget , vol.8 , pp. 3581-3590
    • Fendler, W.P.1    Reinhardt, S.2    Ilhan, H.3    Delker, A.4    Boning, G.5    Gildehaus, F.J.6
  • 18
    • 85009062605 scopus 로고    scopus 로고
    • German multicenter study investigating 177Lu-PSMA-617 radioligand therapy in advanced prostate cancer patients
    • Rahbar K, Ahmadzadehfar H, Kratochwil C, Haberkorn U, Schafers M, Essler M et al. German multicenter study investigating 177Lu-PSMA-617 radioligand therapy in advanced prostate cancer patients. J Nucl Med 2017; 58: 85-90.
    • (2017) J Nucl Med , vol.58 , pp. 85-90
    • Rahbar, K.1    Ahmadzadehfar, H.2    Kratochwil, C.3    Haberkorn, U.4    Schafers, M.5    Essler, M.6
  • 19
    • 85030777222 scopus 로고    scopus 로고
    • Final results of 2-dose fractionation of 177Lu-J591 for progressive metastatic castration-resistant prostate cancer (mCRPC) Conference: 2016 annual meeting of the American society of clinical oncology, asco
    • abstract 5022
    • Tagawa ST, Batra J, Vallabhajosula S, Jhanwar Y, Christos PJ, Emmerich L et al. Final results of 2-dose fractionation of 177Lu-J591 for progressive metastatic castration-resistant prostate cancer (mCRPC). Conference: 2016 Annual Meeting of the American Society of Clinical Oncology, ASCO. J Clin Oncol 2016; 34 (abstract 5022).
    • (2016) J Clin Oncol , vol.34
    • Tagawa, S.T.1    Batra, J.2    Vallabhajosula, S.3    Jhanwar, Y.4    Christos, P.J.5    Emmerich, L.6
  • 20
    • 85030787424 scopus 로고    scopus 로고
    • Assessment of response, clinical evaluation and toxicity of radioligand therapy (RLT) with 177- Lutetium-DKFZ-617-labeled prostate specific membrane antigen (177-Lu-DKFZ-617-PSMA) for metastatic castrate resistant prostate cancer (mCRPC): An initial experience in Jaslok conference: 29th annual congress of the european association of nuclear medicine, EANM 2016, Spain
    • Rathore H, Shah H, Aland P, Chaudhuri P, Bharadwaj T, Kale C et al. Assessment of response, clinical evaluation and toxicity of radioligand therapy (RLT) with 177- Lutetium-DKFZ-617-labeled prostate specific membrane antigen (177-Lu-DKFZ-617-PSMA) for metastatic castrate resistant prostate cancer (mCRPC): an initial experience in Jaslok. Conference: 29th Annual Congress of the European Association of Nuclear Medicine, EANM 2016, Spain. Eur J Nucl Med Mol Imaging 2016; 43: S414.
    • (2016) Eur J Nucl Med Mol Imaging , vol.43 , pp. S414
    • Rathore, H.1    Shah, H.2    Aland, P.3    Chaudhuri, P.4    Bharadwaj, T.5    Kale, C.6
  • 21
    • 84981294507 scopus 로고    scopus 로고
    • 177Lu-DKFZPSMA- 617 therapy in metastatic castration resistant prostate cancer: Safety, efficacy, and quality of life assessment
    • Yadav MP, Ballal S, Tripathi M, Damle NA, Sahoo RK, Seth A et al. 177Lu-DKFZPSMA- 617 therapy in metastatic castration resistant prostate cancer: safety, efficacy, and quality of life assessment. Eur J Nucl Med Mol Imaging 2017; 44: 81-91.
    • (2017) Eur J Nucl Med Mol Imaging , vol.44 , pp. 81-91
    • Yadav, M.P.1    Ballal, S.2    Tripathi, M.3    Damle, N.A.4    Sahoo, R.K.5    Seth, A.6
  • 22
    • 80054690379 scopus 로고    scopus 로고
    • Characterising the castration-resistant prostate cancer population: A systematic review
    • Kirby M, Hirst C, Crawford ED. Characterising the castration-resistant prostate cancer population: a systematic review. Int J Clin Pract 2011; 65: 1180-1192.
    • (2011) Int J Clin Pract , vol.65 , pp. 1180-1192
    • Kirby, M.1    Hirst, C.2    Crawford, E.D.3
  • 23
    • 84908450488 scopus 로고    scopus 로고
    • Systemic therapy in men with metastatic castration-resistant prostate cancer: American society of clinical oncology and cancer care, Ontario clinical practice guideline
    • Basch E, Loblaw DA, Oliver TK, Carducci M, Chen RC, Frame JN et al. Systemic therapy in men with metastatic castration-resistant prostate cancer: American Society of Clinical Oncology and Cancer Care, Ontario clinical practice guideline. J Clin Oncol 2014; 32: 3436-3448.
    • (2014) J Clin Oncol , vol.32 , pp. 3436-3448
    • Basch, E.1    Loblaw, D.A.2    Oliver, T.K.3    Carducci, M.4    Chen, R.C.5    Frame, J.N.6
  • 27
    • 84941009295 scopus 로고    scopus 로고
    • Auger radiopharmaceutical therapy targeting prostate-specific membrane antigen
    • Kiess A, Minn I, Chen Y, Hobbs R, Sgouros G, Mease RC et al. Auger radiopharmaceutical therapy targeting prostate-specific membrane antigen. J Nucl Med 2015; 56: 1401-1407.
    • (2015) J Nucl Med , vol.56 , pp. 1401-1407
    • Kiess, A.1    Minn, I.2    Chen, Y.3    Hobbs, R.4    Sgouros, G.5    Mease, R.C.6
  • 28
    • 85030757766 scopus 로고    scopus 로고
    • Phase i trial of fractionated-dose 177Lutetium radiolabeled anti-prostatespecific membrane antigen (PSMA) monoclonal antibody J591 (177Lu-J591) for metastatic castration-resistant prostate cancer (CRPC) Conference: European cancer congress, ECC 2013 Amsterdam, Netherlands
    • Tagawa ST, Akhtar NH, Nikolopoulou A, Vallabhajosula S, Osborne J, Beltran H et al. Phase I trial of fractionated-dose 177Lutetium radiolabeled anti-prostatespecific membrane antigen (PSMA) monoclonal antibody J591 (177Lu-J591) for metastatic castration-resistant prostate cancer (CRPC). Conference: European Cancer Congress, ECC 2013, Amsterdam, Netherlands. Eur J Cancer 2013; 49: S701-S702.
    • (2013) Eur J Cancer , vol.49 , pp. S701-S702
    • Tagawa, S.T.1    Akhtar, N.H.2    Nikolopoulou, A.3    Vallabhajosula, S.4    Osborne, J.5    Beltran, H.6
  • 29
    • 85030781457 scopus 로고    scopus 로고
    • Phase i trial of docetaxel/prednisone plus fractionated dose radiolabeled anti-prostate-specific membrane antigen (PSMA) monoclonal antibody 177Lu- J591 in patients with metastatic, castration-resistant prostate cancer (mCRPC) Conference: Annual meeting of the American society of clinical oncology, ASCO, Chicago, United States 2014
    • Tagawa ST, Whang YE, Kaur G, Vallabhajosula S, Christos PJ, Nikolopoulou A et al. Phase I trial of docetaxel/prednisone plus fractionated dose radiolabeled anti-prostate-specific membrane antigen (PSMA) monoclonal antibody 177Lu- J591 in patients with metastatic, castration-resistant prostate cancer (mCRPC). Conference: Annual Meeting of the American Society of Clinical Oncology, ASCO, Chicago, United States, 2014. J Clin Oncol 2014; 32 (Suppl 1): 15.
    • (2014) J Clin Oncol , vol.32 , pp. 15
    • Tagawa, S.T.1    Whang, Y.E.2    Kaur, G.3    Vallabhajosula, S.4    Christos, P.J.5    Nikolopoulou, A.6
  • 31
    • 77957682309 scopus 로고    scopus 로고
    • Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: A randomised openlabel trial
    • De Bono JS, Oudard S, Ozguroglu M, Hansen S, Machiels JP, Kocak I et al. Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised openlabel trial. Lancet 2010; 376: 1147-1154.
    • (2010) Lancet , vol.376 , pp. 1147-1154
    • De Bono, J.S.1    Oudard, S.2    Ozguroglu, M.3    Hansen, S.4    Machiels, J.P.5    Kocak, I.6
  • 32
    • 80053085982 scopus 로고    scopus 로고
    • End points and outcomes in castration resistant prostate cancer: From clinical trials to clinical practice
    • Scher HI, Morris MJ, Basch E, Heller G. End points and outcomes in castration resistant prostate cancer: from clinical trials to clinical practice. J Clin Oncol 2011; 29: 3695-3704.
    • (2011) J Clin Oncol , vol.29 , pp. 3695-3704
    • Scher, H.I.1    Morris, M.J.2    Basch, E.3    Heller, G.4
  • 34
    • 0030219893 scopus 로고    scopus 로고
    • Upregulation of prostate-specific membrane antigen after androgen-deprivation therapy
    • Wright GL Jr, Grob BM, Haley C, Grossman K, Newhall K, Petrylak D et al. Upregulation of prostate-specific membrane antigen after androgen-deprivation therapy. Urology 1996; 48: 326-334.
    • (1996) Urology , vol.48 , pp. 326-334
    • Wright, G.L.1    Grob, B.M.2    Haley, C.3    Grossman, K.4    Newhall, K.5    Petrylak, D.6
  • 35
    • 78049527402 scopus 로고    scopus 로고
    • External irradiation with or without long-term androgen suppression for prostate cancer with high metastatic risk: 10-year results of an EORTC randomised study
    • Bolla M, Van Tienhoven G, Warde P, Dubois JB, Mirimanoff RO, Storme G et al. External irradiation with or without long-term androgen suppression for prostate cancer with high metastatic risk: 10-year results of an EORTC randomised study. Lancet Oncol 2010; 11: 1066-1073.
    • (2010) Lancet Oncol , vol.11 , pp. 1066-1073
    • Bolla, M.1    Van Tienhoven, G.2    Warde, P.3    Dubois, J.B.4    Mirimanoff, R.O.5    Storme, G.6
  • 36
    • 84945895120 scopus 로고    scopus 로고
    • Androgen receptor upregulation mediates radioresistance after ionizing radiation
    • Spratt DE, Evans MJ, Davis BJ, Doran MG, Lee MX, Shah N et al. Androgen receptor upregulation mediates radioresistance after ionizing radiation. Cancer Res 2015; 75: 4688-4696.
    • (2015) Cancer Res , vol.75 , pp. 4688-4696
    • Spratt, D.E.1    Evans, M.J.2    Davis, B.J.3    Doran, M.G.4    Lee, M.X.5    Shah, N.6
  • 37
    • 85001831561 scopus 로고    scopus 로고
    • Correlation of PSMA-targeted 18F-DCFPyL PET/CT findings with immunohistochemical and genomic data in a patient with metastatic neuroendocrine prostate cancer
    • Tosoian JJ, Gorin MA, Rowe SP, Andreas D, Szabo Z, Pienta KJ et al. Correlation of PSMA-targeted 18F-DCFPyL PET/CT findings with immunohistochemical and genomic data in a patient with metastatic neuroendocrine prostate cancer. Clin Genitourin Cancer 2017; 15: e65-e68.
    • (2017) Clin Genitourin Cancer , vol.15 , pp. e65-e68
    • Tosoian, J.J.1    Gorin, M.A.2    Rowe, S.P.3    Andreas, D.4    Szabo, Z.5    Pienta, K.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.