The RNA helicase DDX46 inhibits innate immunity by entrapping m 6 A-demethylated antiviral transcripts in the nucleus

Nature Immunology

Volumn 18, Issue 10, 2017, Pages 1094-1103

  Zheng, Qingliang ^a   Hou, Jin ^b   Zhou, Ye ^b   Li, Zhenyang ^b   Cao, Xuetao ^a,b  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE INHIBITOR; ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 5; ANTIVIRUS AGENT; DEAD BOX PROTEIN 17; DEAD BOX PROTEIN 23; DEAD BOX PROTEIN 39; DEAD BOX PROTEIN 42; DEAD BOX PROTEIN 46; DEAD BOX PROTEIN 48; DEAD BOX PROTEIN 5; INTERFERON; RNA HELICASE; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG; 6-METHYLADENINE; ADENINE; DEAD BOX PROTEIN; MESSENGER RNA; PROTEIN BINDING;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEMETHYLATION; ENZYME INHIBITION; HUMAN; IMMUNE RESPONSE; IN VIVO STUDY; INFLAMMATORY DISEASE; INNATE IMMUNITY; INTERFERON PRODUCTION; PERITONEUM MACROPHAGE; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN RNA BINDING; RNA SPLICING; RNA TRANSLATION; VESICULAR STOMATITIS; ANALOGS AND DERIVATIVES; ANIMAL; BINDING SITE; BIOSYNTHESIS; CELL LINE; CELL NUCLEUS; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM; MOUSE; NUCLEOTIDE MOTIF; PHYSIOLOGY; RNA TRANSPORT; VESICULOVIRUS; VIRUS REPLICATION;

ADENINE; ALKB HOMOLOG 5, RNA DEMETHYLASE; ANIMALS; BINDING SITES; CELL LINE; CELL NUCLEUS; DEAD-BOX RNA HELICASES; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; HUMANS; IMMUNITY, INNATE; INTERFERON TYPE I; MACROPHAGES; MICE; MICE, KNOCKOUT; NUCLEOTIDE MOTIFS; PROTEIN BINDING; RNA TRANSPORT; RNA, MESSENGER; TRANSCRIPTION, GENETIC; VESICULAR STOMATITIS; VESICULOVIRUS; VIRUS REPLICATION;

EID: 85030610496     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3830     Document Type: Article

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