Activation and inhibition of adaptive immune response mediated by mast cells

Journal of Biological Regulators and Homeostatic Agents

Volumn 31, Issue 3, 2017, Pages 543-548

  Toniato, E ^a   Frydas, I ^b   Robuffo, I ^c   Ronconi, G ^d   Caraffa, Al ^e   Kritas, S K ^f   Conti, P ^a  

^a UNIVERSITY OF CHIETI   (Italy)

^b ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^c CNR   (Italy)

^d FONDAZIONE POLICLINICO UNIVERSITARIO A GEMELLI IRCCS   (Italy)

^e UNIVERSITY OF PERUGIA   (Italy)

^f ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

Adaptive immunity; Cytokines; IL 37; Inflammation; Mast cells

Indexed keywords

GROWTH FACTOR; IMMUNOGLOBULIN E; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 18; INTERLEUKIN 33; INTERLEUKIN 37; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR AP 1; ALLERGEN; FCRI PROTEIN, HUMAN; IL37 PROTEIN, HUMAN; INTERLEUKIN 1; MYD88 PROTEIN, HUMAN; SIGNAL PEPTIDE; TOLL LIKE RECEPTOR;

ADAPTIVE IMMUNITY; ALLERGY; ANAPHYLAXIS; ASTHMA; CD4+ T LYMPHOCYTE; CELL ACTIVATION; CYTOKINE RELEASE; INFLAMMATION; INNATE IMMUNITY; MAST CELL; NONHUMAN; REVIEW; ANIMAL; HUMAN; HYPERSENSITIVITY; IMMUNOLOGY; IMMUNOMODULATION; TH2 CELL;

ADAPTIVE IMMUNITY; ALLERGENS; ANIMALS; HUMANS; HYPERSENSITIVITY; IMMUNOGLOBULIN E; IMMUNOMODULATION; INTERLEUKIN-1; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAST CELLS; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; TH2 CELLS; TOLL-LIKE RECEPTORS; TRANSCRIPTION FACTOR AP-1;

EID: 85030567385     PISSN: 0393974X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (24)

1. Nakae S, Iikura M, Suto H, et al. TIM-1 and TIM-3 enhancement of Th2 cytokine production by mast cells. Blood 2007; 110(7):25656-8.
2. Galli SJ. Mast cells and KIT as potential therapeutic targets in severe asthma. N Engl J Med 2017; 376(20):1983-84.
3. Sismanopoulos N, Delivanis DA, Mavrommati D, Hatziagelaki E, Conti P, Theoharides TC. Do mast cells link obesity and asthma? Allergy 2013; 68(1):8-15.
4. Taracanova A, Alevizos M, Karagkouni A, et al. SP and IL-33 together markedly enhance TNF synthesis and secretion from human mast cells mediated by the interaction of their receptors. Proc Natl Acad Sci U S A 2017; 114(20):E4002-E4009.
5. Conti P, Caraffa Al, Kritas SK, Ronconi G, Lessiani G, Toniato E, Theoharides TC. Mast cell, pro-inflammatory and anti-inflammatory: Jekyll and Hyde, the story continues. J Biol Regul Homeost Agents 2017; 31(2):263-67.
6. Shaik-Dasthagirisaheb YB, Conti P. The role of mast cells in Alzheimers Disease. Adv Clin Exp Med 2016; 25(4):781-87.
7. Galli SJ, Gaudenzio N. Human mast cells as antigen-presenting cells: When is this role important in vivo? J Allergy Clin Immunol 2017. doi: 10.1016/j.jaci.2017.05.029.
8. Theoharides TC, Stewart JM, Tsilioni I. Tolerability and benefit of a tetramethoxyluteolin-containing skin lotion. Int J Immunopathol Pharmacol 2017; 30(2):146-51.
9. Pandolfi F, Cianci R, Cammarota G, Pagliari D, Landolfi R, Conti P, Theoharides TC. Recent insights in primary immunodeficiency diseases: The role of T-lymphocytes and innate immunity. Ann Clin Lab Sci 2010; 40(1):3-9.
10. Zhan Q, Zeng Q, Song R, et al. IL-37 suppresses MyD88-mediated inflammatory responses in human aortic valve interstitial cells. Mol Med 2017; doi: 10.2119/molmed.2017.00022).
11. Kempuraj D, Caraffa A, Ronconi G, Lessiani G, Conti P. Are mast cells important in diabetes? Pol J Pathol 2016; 67(3):199-206.
12. Conti P, Kempuraj D. Important role of mast cells in multiple sclerosis. Mult Scler Relat Disord 2016; 5:77-80.
13. Conti P, Carinci F, Lessiani G, et al. Potential therapeutic use of IL-37: A key suppressor of innate immunity and allergic immune responses mediated by mast cells. Immunol Res 2017 doi: 10.1007/s12026-017-8938-7.
14. Yang L, Yue Ting Y, Shen Y, et al. 17β-estradiol modulates the viability, phenotype, endocytosis, and inflammatory cytokine expression of RAW264.7 macrophages. Eur J Inflamm 2016; (1):10-17.
15. Morita H, Arae K, Unno H, et al. An interleukin-33-mast cell-interleukin-2 axis suppresses papain-induced allergic inflammation by promoting regulatory T cell numbers. Immunity 2015; 43(1):175-86.
16. Zhan Q, Zeng Q, Song R, et al. IL-37 suppresses MyD88-mediated inflammatory responses in human aortic valve interstitial cells. Mol Med 2017; doi: 10.2119/molmed.2017.00022.
17. Theoharides TC, Petra AI, Taracanova A, Panagiotidou S, Conti P. Targeting IL-33 in autoimmunity and inflammation. J Pharmacol Exp Ther 2015; 54(1):24-31.
18. Cherry WB, Yoon J, Bartemes KR, Iijima K, Kita H. A novel IL-1 family cytokine, IL-33, potently activates human eosinophils. J Allergy Clin Immunol 2008; 121(6):1484-90.
19. Cherry WB, Yoon J, Bartemes KR, Iijima K, Kita H. A novel IL-1 family cytokine, IL-33, potently activates human eosinophils. J Allergy Clin Immunol 2008; 121(6):1484-90.
20. Eiwegger T, Akdis CA. IL-33 links tissue cells, dendritic cells and Th2 cell development in a mouse model of asthma. Eur J Immunol 2011; 41:1535-38.
21. Novick D, Kim S, Kaplanski G, Dinarello CA. Interleukin-18, more than a Th1 cytokine. Semin Immunol 2013; 25(6):439-48.
22. Garlanda C, Dinarello CA, Mantovani A. The interleukin-1 family: back to the future. Immunity 2013; 39(6):1003-18.
23. Carinci F, Lessiani G, Spinas E, Kritas SK, Ronconi G, Caraffa A, Conti P. Mast cell and cancer with special emphasis on IL-37 an anti-inflammatory and inhibitor of innate immunity: new frontiers. J Biol Regul Homeost Agents 2016; 30(4):945-50.
24. Conti P, Ronconi G, Caraffa A, Lessiani G, Duraisamy K. il-37 a new IL-1 family member emerges as a key suppressor of asthma mediated by mast cells. Immunol Invest 2017; 46(3):239-50.