-
1
-
-
0022649225
-
A prospective trial of Intravenous Streptokinase in Acute Myocardial Infarction (ISAM): Mortality, morbidity and infarct size at 21 days
-
ISAM Study Group. A prospective trial of Intravenous Streptokinase in Acute Myocardial Infarction (ISAM): mortality, morbidity and infarct size at 21 days. N Engl J Med 1986; 314:1465-71
-
(1986)
N Engl J Med
, vol.314
, pp. 1465-1471
-
-
-
2
-
-
0022640774
-
Effectiveness of thrombolytic treatment in acute myocardial infarction
-
Gruppo Italiano per lo Studio della Streptochinasi nell’Infarto Miocardico (GISSI). Effectiveness of thrombolytic treatment in acute myocardial infarction. Lancet 1986;1:397-102
-
(1986)
Lancet
, vol.1
, pp. 102-397
-
-
-
3
-
-
0023775427
-
Intravenous tissue plasminogen activator and size of infarct, left ventricular function, and survival in acute myocardial infarction
-
Van de Werf F, Arnold AER. Intravenous tissue plasminogen activator and size of infarct, left ventricular function, and survival in acute myocardial infarction. BMJ 1988;297:1374-8
-
(1988)
BMJ
, vol.297
, pp. 1374-1378
-
-
Van De Werf, F.1
Arnold, A.2
-
4
-
-
0023783508
-
Trial of tissue plasminogen activator for mortality reduction in acute myocardial infarction: Anglo Scandinavian Study of early thrombolysis (ASSET)
-
Wilcox RG, von der Lippe G, Olsson CG, Jensen G, Skene AM, Hampton JR. Trial of tissue plasminogen activator for mortality reduction in acute myocardial infarction: Anglo Scandinavian Study of early thrombolysis (ASSET). Lancet 1988;2:525-30
-
(1988)
Lancet
, vol.2
, pp. 525-530
-
-
Wilcox, R.G.1
Von Der Lippe, G.2
Olsson, C.G.3
Jensen, G.4
Skene, A.M.5
Hampton, J.R.6
-
5
-
-
0023805341
-
Randomized trial of intravenous streptokinase, oral aspirin, both or neither among 17,187 cases of suspected, acute myocardial infarction: ISIS-2
-
ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Randomized trial of intravenous streptokinase, oral aspirin, both or neither among 17,187 cases of suspected, acute myocardial infarction: ISIS-2. Lancet 198S;2:349-60
-
Lancet 198S
, vol.2
, pp. 349-360
-
-
-
6
-
-
0025092298
-
For the HART Investigators. A comparison between heparin and low dose aspirin as conjunctive therapy with tissue plasminogen activator for acute myocardial infarction
-
Hsia J, Hamilton WP, Kleiman N, Roberts R, Chaitman BR, Ross AM, for the HART Investigators. A comparison between heparin and low dose aspirin as conjunctive therapy with tissue plasminogen activator for acute myocardial infarction. N Engl J Med 1990;323:1433-7
-
(1990)
N Engl J Med
, vol.323
, pp. 1433-1437
-
-
Hsia, J.1
Hamilton, W.P.2
Kleiman, N.3
Roberts, R.4
Chaitman, B.R.5
Ross, A.M.6
-
7
-
-
0025687989
-
Effect of heparin on coronary arterial patency after thrombolysis with tissue plasminogen activator in acute myocardial infarction
-
Bleich SD, Nichols TC, Schumacher RR, Cooke DH, Tate DA, Teichman SL. Effect of heparin on coronary arterial patency after thrombolysis with tissue plasminogen activator in acute myocardial infarction. Am J Cardiol 1990;66:1412-7
-
(1990)
Am J Cardiol
, vol.66
, pp. 1412-1417
-
-
Bleich, S.D.1
Nichols, T.C.2
Schumacher, R.R.3
Cooke, D.H.4
Tate, D.A.5
Teichman, S.L.6
-
8
-
-
0026537021
-
Tijssen J, et al, for the European Cooperative Study Group. Effect of early intravenous heparin on coronary patency, infarct size and bleeding complications after alteplase thrombolysis: Results of a randomized double blind European Cooperative Study Group trial
-
de Bono DP, Simoons ML, Tijssen J, et al, for the European Cooperative Study Group. Effect of early intravenous heparin on coronary patency, infarct size and bleeding complications after alteplase thrombolysis: results of a randomized double blind European Cooperative Study Group trial. Br Heart J 1992;67: 122-8
-
(1992)
Br Heart J
, vol.67
, pp. 122
-
-
De Bono, D.P.1
Simoons, M.L.2
-
9
-
-
0024571383
-
Kereiakes DJ, et al, and the TAMI Study Group. A randomized controlled trial of intravenous tissue plasminogen activator and early intravenous heparin in acute myocardial infarction
-
Topol EJ, George BS, Kereiakes DJ, et al, and the TAMI Study Group. A randomized controlled trial of intravenous tissue plasminogen activator and early intravenous heparin in acute myocardial infarction. Circulation 1989;79:281-6
-
(1989)
Circulation
, vol.79
, pp. 281-286
-
-
Topol, E.J.1
George, B.S.2
-
10
-
-
0025335032
-
GISSI-2: A factorial randomized trial of alteplase versus streptokinase and heparin versus no heparin among 12,490 patients with acute myocardial infarction
-
Gruppo Italiano per lo Studio della Streptochinasi nell’Infarto Miocardico. GISSI-2: a factorial randomized trial of alteplase versus streptokinase and heparin versus no heparin among 12,490 patients with acute myocardial infarction. Lancet 1990;336:65-71
-
(1990)
Lancet
, vol.336
, pp. 65-71
-
-
-
11
-
-
0025329267
-
In-hospital mortality and clinical course of 20,891 patients with suspected acute myocardial infarction randomized between tissue plasminogen activator or streptokinase with or without heparin
-
International Study Group. In-hospital mortality and clinical course of 20,891 patients with suspected acute myocardial infarction randomized between tissue plasminogen activator or streptokinase with or without heparin. Lancet 1990;336:71-5
-
(1990)
Lancet
, vol.336
, pp. 71-75
-
-
-
12
-
-
0026031064
-
Heparin as an conjunctive treatment after thrombolytic therapy for acute myocardial infarction
-
Prins MH, Hirsh J. Heparin as an conjunctive treatment after thrombolytic therapy for acute myocardial infarction. Am J Cardiol 1991;67:3-l 1A
-
(1991)
Am J Cardiol
, vol.67
, Issue.3
, pp. 1A
-
-
Prins, M.H.1
Hirsh, J.2
-
13
-
-
0026607185
-
ISIS-3: A randomized comparison of strepto kinase versus tissue plasminogen activator versus aspirin alone among 41,299 cases of suspected acute myocardial infarction
-
ISIS-3 (Third International Study of Infarct Survival) Collaborative Group. ISIS-3: a randomized comparison of strepto kinase versus tissue plasminogen activator versus aspirin alone among 41,299 cases of suspected acute myocardial infarction. Lancet 1992;339:753-70
-
(1992)
Lancet
, vol.339
, pp. 753-770
-
-
-
14
-
-
0025957848
-
Thrombolysis and myocardial infarction
-
Tiefenbrunn AJ, Sobel BE. Thrombolysis and myocardial infarction. Fibrinolysis 1991;5:1-15
-
(1991)
Fibrinolysis
, vol.5
, pp. 1-15
-
-
Tiefenbrunn, A.J.1
Sobel, B.E.2
-
15
-
-
0025182206
-
Prevention of thrombosis and rethrombosis
-
Runge MS. Prevention of thrombosis and rethrombosis. New approaches. Circulation 1990;82:655-7
-
(1990)
New Approaches
, vol.82
, pp. 655-657
-
-
Runge, M.S.1
-
16
-
-
0025964515
-
Role of new antiplatelet agents as conjunctive therapies in thrombolysis
-
Willerson JT, Golino P, McNatt J, Eidt J, Yao S-K, Buja LM. Role of new antiplatelet agents as conjunctive therapies in thrombolysis. Am J Cardiol 1991;67:12-18A
-
(1991)
Am J Cardiol
, vol.67
, pp. 12A-18A
-
-
Willerson, J.T.1
Golino, P.2
McNatt, J.3
Eidt, J.4
Yao, S.-K.5
Buja, L.M.6
-
17
-
-
0026031065
-
Role of new anticoagulants as conjunctive therapy during thrombolysis
-
Eisenberg PR. Role of new anticoagulants as conjunctive therapy during thrombolysis. Am J Cardiol 1991;67:19-24A
-
(1991)
Am J Cardiol
, vol.67
, pp. 19A-24A
-
-
Eisenberg, P.R.1
-
18
-
-
0025375504
-
Tick anticoagulant peptide (TAP) is a novel inhibitor of blood coagulation factor Xa
-
Waxman L, Smith DE, Arcuri KE, Vlasuk GP: Tick anticoagulant peptide (TAP) is a novel inhibitor of blood coagulation factor Xa. Science 1990;248:593-6
-
(1990)
Science
, vol.248
, pp. 593-596
-
-
Waxman, L.1
Smith, D.E.2
Arcuri, K.E.3
Vlasuk, G.P.4
-
19
-
-
0025163058
-
Characterization of recombinant tick anticoagulant peptide
-
Neeper MP, Waxman L, Smith DE, et al. Characterization of recombinant tick anticoagulant peptide. J Biol Chem 1990;265: 17746-52
-
(1990)
J Biol Chem
, vol.265
, pp. 17746-17752
-
-
Neeper, M.P.1
Waxman, L.2
Smith, D.E.3
-
20
-
-
0025683260
-
Tick anticoagulant peptide: Kinetic analysis of the recombinant inhibitor with blood coagulation factor Xa
-
Jordan SP, Waxman L, Smith DE, Vlasuk GP. Tick anticoagulant peptide: kinetic analysis of the recombinant inhibitor with blood coagulation factor Xa. Biochemistry 1990;29:11095-100
-
(1990)
Biochemistry
, vol.29
, pp. 11095-11100
-
-
Jordan, S.P.1
Waxman, L.2
Smith, D.E.3
Vlasuk, G.P.4
-
21
-
-
0025891319
-
Fujita, et al. Comparison of the in vivo anticoagulant properties of standard heparin and the highly selective factor Xa inhibitors antistasin and tick anticoagulant peptide (rTAP) in a rabbit model of venous thrombosis
-
Vlasuk GP, Ramjit D, Fujita, et al. Comparison of the in vivo anticoagulant properties of standard heparin and the highly selective factor Xa inhibitors antistasin and tick anticoagulant peptide (rTAP) in a rabbit model of venous thrombosis. Thromb Haemost 1991;65:257-62
-
(1991)
Thromb Haemost
, vol.65
, pp. 257-262
-
-
Vlasuk, G.P.1
Ramjit, D.2
-
22
-
-
0026059199
-
Antithrombotic efficacy of recombinant tick anticoagulant peptide. A potent inhibitor of coagulation factor Xa in a primate model of arterial thrombosis
-
Schaffer LW, Davidson JT, Vlasuk GP, Siegl PKS. Antithrombotic efficacy of recombinant tick anticoagulant peptide. A potent inhibitor of coagulation factor Xa in a primate model of arterial thrombosis. Circulation 1991;84:1741-8
-
(1991)
Circulation
, vol.84
, pp. 1741-1748
-
-
Schaffer, L.W.1
Davidson, J.T.2
Vlasuk, G.P.3
Siegl, P.K.S.4
-
23
-
-
0024416485
-
Development of hirudin as an antithrombotic agent
-
Markwardt F. Development of hirudin as an antithrombotic agent. Semin Thromb Hemost 1989;15:269-82
-
(1989)
Semin Thromb Hemost
, vol.15
, pp. 269-282
-
-
Markwardt, F.1
-
24
-
-
0026558347
-
Lynch JJ. Vlasuk GP. Conjunctive enhancement of enzymatic thrombolysis and prevention of thrombotic reocclusion with the selective factor Xa inhibitor tick anticoagulant peptide. Comparison to hirudin and heparin in a canine model of acute coronary artery thrombosis
-
Sitko GR, Ramjit DR, Stabilito II, Lehman D, Lynch JJ. Vlasuk GP. Conjunctive enhancement of enzymatic thrombolysis and prevention of thrombotic reocclusion with the selective factor Xa inhibitor tick anticoagulant peptide. Comparison to hirudin and heparin in a canine model of acute coronary artery thrombosis. Circulation 1992;85:805-15
-
(1992)
Circulation
, vol.85
, pp. 805-815
-
-
Sitko, G.R.1
Ramjit, D.R.2
Stabilito, I.I.3
Lehman, D.4
-
26
-
-
0026651846
-
Pharmacological assessment of the antithrombotic activity of the peptide thrombin inhibitor, D-methyl-phenylalanyl-prolyl-arginal (GYKI-14766), in a canine model of coronary artery thrombosis
-
Jackson CV, Crowe VG, Frank JD, et al. Pharmacological assessment of the antithrombotic activity of the peptide thrombin inhibitor, D-methyl-phenylalanyl-prolyl-arginal (GYKI-14766), in a canine model of coronary artery thrombosis. J Pharmacol Exp Ther 1992;261:546-52
-
(1992)
J Pharmacol Exp Ther
, vol.261
, pp. 546-552
-
-
Jackson, C.V.1
Crowe, V.G.2
Frank, J.D.3
-
27
-
-
0025782444
-
Recombinant hirudin reduces the incidence of thrombotic occlusion in a canine model of coronary vascular injury
-
Homeister JW, Mickelson JK, Hoff PT, Lucchesi BR. Recombinant hirudin reduces the incidence of thrombotic occlusion in a canine model of coronary vascular injury. Coronary Art Dis 1991;2:237-46
-
(1991)
Coronary Art Dis
, vol.2
, pp. 237-246
-
-
Homeister, J.W.1
Mickelson, J.K.2
Hoff, P.T.3
Lucchesi, B.R.4
-
28
-
-
0023412655
-
Buccal mucosa bleeding times of healthy dogs and of dogs in various pathologic states, including thrombocytopenia, uremia and von Willebrand’s disease
-
Jergens AE, Turrentine MA, Krave KH, Johnson GS. Buccal mucosa bleeding times of healthy dogs and of dogs in various pathologic states, including thrombocytopenia, uremia and von Willebrand’s disease. Am J Vet Res 1987;48:1337-12
-
(1987)
Am J Vet Res
, vol.48
, pp. 1337-1412
-
-
Jergens, A.E.1
Turrentine, M.A.2
Krave, K.H.3
Johnson, G.S.4
-
29
-
-
0026502250
-
Przysiecki CT, et ai Large scale purification and characterization of recombinant tick anticoagulant peptide
-
Lehman ED, Schaefer TF, Przysiecki CT, et ai Large scale purification and characterization of recombinant tick anticoagulant peptide. J Chromatogr 1992;574: 225-35
-
(1992)
J Chromatogr
, vol.574
, pp. 225-235
-
-
Lehman, E.D.1
Schaefer, T.F.2
-
30
-
-
0027619013
-
Expression, purification and characterization of multigram amounts of a recombinant hybrid HV1-HV2 himdin variant expressed in Saccharomvces cerevisiae
-
Lehman ED, Joyce JG, Bailey FJ, et al. Expression, purification and characterization of multigram amounts of a recombinant hybrid HV1-HV2 himdin variant expressed in Saccharomvces cerevisiae. Protein Expression Purif 1993;4:247-55
-
(1993)
Protein Expression Purif
, vol.4
, pp. 247-255
-
-
Lehman, E.D.1
Joyce, J.G.2
Bailey, F.J.3
-
31
-
-
0025085821
-
In vivo models of arterial thrombosis and thrombolysis
-
Bush LR, Shebuski RJ. In vivo models of arterial thrombosis and thrombolysis. FASEB J 1990;4:3087-98
-
(1990)
FASEB J
, vol.4
, pp. 3087-3098
-
-
Bush, L.R.1
Shebuski, R.J.2
-
32
-
-
0023749096
-
Influence of selective endoperoxide/thromboxane A: Receptor antagonism with sulotroban on lysis time and reocclusion rate after tissue plasminogen activator-induced coronary thrombolysis in the dog
-
Shebuski RJ, Smith JM, Storer BL, Granett JR, Bugelski PJ. Influence of selective endoperoxide/thromboxane A: receptor antagonism with sulotroban on lysis time and reocclusion rate after tissue plasminogen activator-induced coronary thrombolysis in the dog. J Pharmacol Exp Ther 1988;246:790-6
-
(1988)
J Pharmacol Exp Ther
, vol.246
, pp. 790-796
-
-
Shebuski, R.J.1
Smith, J.M.2
Storer, B.L.3
Granett, J.R.4
Bugelski, P.J.5
-
33
-
-
0024393955
-
Role of thrombin and thromboxane A; in reocclusion following coronary thrombolysis with tissue-type plasminogen activator
-
Fitzgerald DJ, FitzGerald GA. Role of thrombin and thromboxane A;in reocclusion following coronary thrombolysis with tissue-type plasminogen activator. Proc Natl Acad Sci USA 1989;86:7585-9
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 7585-7589
-
-
Fitzgerald, D.J.1
Fitzgerald, G.A.2
-
34
-
-
0024339744
-
Increased thromboxane biosynthesis during coronary thrombolysis. Evidence that platelet activation and thromboxane A, modulate the response to tissue-type plasminogen activator in vivo
-
Fitzgerald DJ, Wright F, FitzGerald GA. Increased thromboxane biosynthesis during coronary thrombolysis. Evidence that platelet activation and thromboxane A, modulate the response to tissue-type plasminogen activator in vivo. Circ Res 1989;65:83-94
-
(1989)
Circ Res
, vol.65
, pp. 83-94
-
-
Fitzgerald, D.J.1
Wright, F.2
Fitzgerald, G.A.3
-
35
-
-
0026099431
-
Relative efficacy of antithrombin compared with antiplatelet agents in accelerating coronary thrombolysis and preventing early reocclusion
-
Haskel EJ, Prager NA, Sobel BE, Abendschein DR. Relative efficacy of antithrombin compared with antiplatelet agents in accelerating coronary thrombolysis and preventing early reocclusion. Circulation 1991;83:1048-56
-
(1991)
Circulation
, vol.83
, pp. 1048-1056
-
-
Haskel, E.J.1
Prager, N.A.2
Sobel, B.E.3
Abendschein, D.R.4
-
36
-
-
0026499492
-
Combination of inhibition of thrombin and blockade of thromboxane A, synthetase and receptors enhances thrombolysis and delays reocclusion in canine coronary arteries
-
Yao S-K, Ober JC, Ferguson JJ, et al. Combination of inhibition of thrombin and blockade of thromboxane A, synthetase and receptors enhances thrombolysis and delays reocclusion in canine coronary arteries. Circulation 1992;86:1993-9
-
(1992)
Circulation
, vol.86
, pp. 1993-1999
-
-
Yao, S.-K.1
Ober, J.C.2
Ferguson, J.J.3
-
37
-
-
0027207766
-
Maintenance of patency after thrombolysis in stenotic coronary arteries requires combined inhibition of thrombin and platelets
-
Prager NA, Torr-Brown SR, Sobel BE. Abendschein DR. Maintenance of patency after thrombolysis in stenotic coronary arteries requires combined inhibition of thrombin and platelets. J Am Coll Cardiol 1993;22:296-301
-
(1993)
J am Coll Cardiol
, vol.22
, pp. 296-301
-
-
Prager, N.A.1
Torr-Brown, S.R.2
Sobel, B.E.3
Abendschein, D.R.4
-
38
-
-
0018891865
-
Electrical induction of coronary artery thrombosis in the ambulatory canine: A model for in vivo evaluation of antithrombotic agents
-
Romson JL, Haack DW, Lucchesi BR. Electrical induction of coronary artery thrombosis in the ambulatory canine: a model for in vivo evaluation of antithrombotic agents. Thromb Res 1980;17:841-53
-
(1980)
Thromb Res
, vol.17
, pp. 841-853
-
-
Romson, J.L.1
Haack, D.W.2
Lucchesi, B.R.3
-
40
-
-
0024582671
-
Effects of thrombin inhibition on the development of acute platelet-thrombus deposition during angioplasty in pigs. Heparin vs recombinant hirudin, a specific thrombin inhibitor
-
Heras M, Chesebro JH, Penny WJ, Bailey KR. Badimon L, Fuster V. Effects of thrombin inhibition on the development of acute platelet-thrombus deposition during angioplasty in pigs. Heparin vs recombinant hirudin, a specific thrombin inhibitor. Circulation 1989;79:657-65
-
(1989)
Circulation
, vol.79
, pp. 657-665
-
-
Heras, M.1
Chesebro, J.H.2
Penny, W.J.3
Bailey, K.R.4
Badimon, L.5
Fuster, V.6
-
41
-
-
0025563384
-
Hirudin, heparin and placebo during deep arterial injury in the pig. The in vivo role of thrombin in platelet-mediated thrombosis
-
Heras M, Chesebro JH, Webster MWI, et al. Hirudin, heparin and placebo during deep arterial injury in the pig. The in vivo role of thrombin in platelet-mediated thrombosis. Circulation 1990;82: 1476-84
-
(1990)
Circulation
, vol.82
, pp. 1476-1484
-
-
Heras, M.1
Chesebro, J.H.2
Webster, M.3
-
42
-
-
0026073345
-
Hirudin interruption of heparin-resistant arterial thrombus formation in baboons
-
Kelly AB, Marzec UM, Hrupski W, et al. Hirudin interruption of heparin-resistant arterial thrombus formation in baboons. Blood 1991;5:1006-12
-
(1991)
Blood
, vol.5
, pp. 1006-1012
-
-
Kelly, A.B.1
Marzec, U.M.2
Hrupski, W.3
-
43
-
-
0026320287
-
Anticoagulant effects of the selective factor Xa inhibitors tick anticoagulant peptide and antistasin in the APTT assay are determined by the relative rate of prothrombinase inhibition
-
Dunwiddie CT, Smith DE, Nutt EM, Vlasuk GP. Anticoagulant effects of the selective factor Xa inhibitors tick anticoagulant peptide and antistasin in the APTT assay are determined by the relative rate of prothrombinase inhibition. Thromb Res 1991:64: 787-94
-
(1991)
Thromb Res
, vol.64
, pp. 787-794
-
-
Dunwiddie, C.T.1
Smith, D.E.2
Nutt, E.M.3
Vlasuk, G.P.4
|