-
1
-
-
84896698630
-
Cutaneous melanoma
-
Eggermont, A.M.M., Spatz, A., Robert, C., Cutaneous melanoma. Lancet 383 (2014), 816–827.
-
(2014)
Lancet
, vol.383
, pp. 816-827
-
-
Eggermont, A.M.M.1
Spatz, A.2
Robert, C.3
-
2
-
-
85026239318
-
Survival of patients with advanced metastatic melanoma: the impact of novel therapies-update 2017
-
Ugurel, S., Röhmel, J., Ascierto, P.A., et al. Survival of patients with advanced metastatic melanoma: the impact of novel therapies-update 2017. Eur J Cancer 83 (2017), 247–257.
-
(2017)
Eur J Cancer
, vol.83
, pp. 247-257
-
-
Ugurel, S.1
Röhmel, J.2
Ascierto, P.A.3
-
3
-
-
84933678156
-
Adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): a randomised, double-blind, phase 3 trial
-
Eggermont, A.M., Chiarion-Sileni, V., Grob, J.J., et al. Adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): a randomised, double-blind, phase 3 trial. Lancet Oncol 16:5 (2015 May), 522–530.
-
(2015)
Lancet Oncol
, vol.16
, Issue.5
, pp. 522-530
-
-
Eggermont, A.M.1
Chiarion-Sileni, V.2
Grob, J.J.3
-
4
-
-
84994874924
-
Prolonged survival with Ipilimumab as adjuvant in stage III melanoma
-
Eggermont, A.M., Chiarion-Sileni, V., Grob, J.J., et al. Prolonged survival with Ipilimumab as adjuvant in stage III melanoma. New Engl J Med 375 (2016), 1845–1855.
-
(2016)
New Engl J Med
, vol.375
, pp. 1845-1855
-
-
Eggermont, A.M.1
Chiarion-Sileni, V.2
Grob, J.J.3
-
5
-
-
84994236251
-
Adjuvant ipilimumab in stage III melanoma: new landscape, new questions
-
Eggermont, A.M., Adjuvant ipilimumab in stage III melanoma: new landscape, new questions. Eur J Cancer 69 (2016), 39–42.
-
(2016)
Eur J Cancer
, vol.69
, pp. 39-42
-
-
Eggermont, A.M.1
-
6
-
-
85033400433
-
Adjuvant nivolumab versus ipilimumab in resected stage III or IV melanoma
-
[Epub ahead of print]
-
Weber, J., Mandala, M., Del Vecchio, M., et al. Adjuvant nivolumab versus ipilimumab in resected stage III or IV melanoma. N Engl J Med, 2017 Sep 10, 10.1056/NEJMoa1709030 [Epub ahead of print].
-
(2017)
N Engl J Med
-
-
Weber, J.1
Mandala, M.2
Del Vecchio, M.3
-
7
-
-
85033203396
-
Adjuvant dabrafenib plus trametinib in stage III BRAF-mutated melanoma
-
[Epub ahead of print]
-
Long, G.V., Hauschild, A., Santinami, M., et al. Adjuvant dabrafenib plus trametinib in stage III BRAF-mutated melanoma. N Engl J Med, 2017 Sep 10, 10.1056/NEJMoa1708539 [Epub ahead of print].
-
(2017)
N Engl J Med
-
-
Long, G.V.1
Hauschild, A.2
Santinami, M.3
-
8
-
-
74949143594
-
Final version of 2009 AJCC melanoma staging and classification
-
Balch, C.M., Gershenwald, J.E., Soong, S.-J., et al. Final version of 2009 AJCC melanoma staging and classification. J Clin Oncol 27 (2009), 6199–6206.
-
(2009)
J Clin Oncol
, vol.27
, pp. 6199-6206
-
-
Balch, C.M.1
Gershenwald, J.E.2
Soong, S.-J.3
-
9
-
-
77952532215
-
Multivariate analysis of prognostic factors among 2,313 patients with stage III melanoma: comparison of nodal micrometastases versus macrometastases
-
Balch, C.M., Gershenwald, J.E., Soong, S.-J., et al. Multivariate analysis of prognostic factors among 2,313 patients with stage III melanoma: comparison of nodal micrometastases versus macrometastases. J Clin Oncol 28 (2010), 2452–2459.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2452-2459
-
-
Balch, C.M.1
Gershenwald, J.E.2
Soong, S.-J.3
-
10
-
-
77955919194
-
EORTC Melanoma Group sentinel node protocol identifies high rate of submicrometastases according to Rotterdam Criteria
-
van der Ploeg, A.P., van Akkooi, A.C., Schmitz, P.I., Koljenovic, S., Verhoef, C., Eggermont, A.M., EORTC Melanoma Group sentinel node protocol identifies high rate of submicrometastases according to Rotterdam Criteria. Eur J Cancer 46 (2010), 2414–2421.
-
(2010)
Eur J Cancer
, vol.46
, pp. 2414-2421
-
-
van der Ploeg, A.P.1
van Akkooi, A.C.2
Schmitz, P.I.3
Koljenovic, S.4
Verhoef, C.5
Eggermont, A.M.6
-
11
-
-
58149375115
-
Sentinel node tumor burden according to the Rotterdam criteria is the most important prognostic factor for survival in melanoma patients: a multicenter study in 388 patients with positive sentinel nodes
-
Van Akkooi, A.C.J., Nowecki, Z.I., Voit, C., et al. Sentinel node tumor burden according to the Rotterdam criteria is the most important prognostic factor for survival in melanoma patients: a multicenter study in 388 patients with positive sentinel nodes. Ann Surg 248 (2008), 949–955.
-
(2008)
Ann Surg
, vol.248
, pp. 949-955
-
-
Van Akkooi, A.C.J.1
Nowecki, Z.I.2
Voit, C.3
-
12
-
-
79957970164
-
Prognosis in patients with sentinel node-positive melanoma is accurately defined by the combined Rotterdam tumor load and Dewar topography criteria
-
Van der Ploeg, A.P.T., Van Akkooi, A.C.J., Rutkowski, P., et al. Prognosis in patients with sentinel node-positive melanoma is accurately defined by the combined Rotterdam tumor load and Dewar topography criteria. J Clin Oncol 29 (2011), 2206–2214.
-
(2011)
J Clin Oncol
, vol.29
, pp. 2206-2214
-
-
Van der Ploeg, A.P.T.1
Van Akkooi, A.C.J.2
Rutkowski, P.3
-
13
-
-
84891627916
-
The prognostic significance of sentinel node tumour burden in melanoma patients: an international, multicenter study of 1539 sentinel node-positive melanoma patients
-
Van der Ploeg, A.P., van Akkooi, A.C., Haydu, L.E., et al. The prognostic significance of sentinel node tumour burden in melanoma patients: an international, multicenter study of 1539 sentinel node-positive melanoma patients. Eur J Cancer 50 (2014), 111–120.
-
(2014)
Eur J Cancer
, vol.50
, pp. 111-120
-
-
Van der Ploeg, A.P.1
van Akkooi, A.C.2
Haydu, L.E.3
-
14
-
-
85027501801
-
Pembrolizumab versus ipilimumab for advanced melanoma: final overall survival results of a multicentre, randomised, open-label phase 3 study (KEYNOTE-006)
-
pii: S0140-6736(17)31601-X. [Epub ahead of print]
-
Schachter, J., Ribas, A., Long, G.V., et al. Pembrolizumab versus ipilimumab for advanced melanoma: final overall survival results of a multicentre, randomised, open-label phase 3 study (KEYNOTE-006). Lancet, 2017 Aug 16, 10.1016/S0140-6736(17)31601-X pii: S0140-6736(17)31601-X. [Epub ahead of print].
-
(2017)
Lancet
-
-
Schachter, J.1
Ribas, A.2
Long, G.V.3
-
15
-
-
85030180429
-
Overall survival with combined therapy with nivolumab and ipilimumab in melanoma
-
[Epub ahead of print]
-
Wolchok, J.D., Chiarion-Seleni, V., Gonzalez, R., et al. Overall survival with combined therapy with nivolumab and ipilimumab in melanoma. N Engl J Med, 2017 Sep 10, 10.1056/NEJMoa1708539 [Epub ahead of print].
-
(2017)
N Engl J Med
-
-
Wolchok, J.D.1
Chiarion-Seleni, V.2
Gonzalez, R.3
-
16
-
-
84964345287
-
Cutaneous, gastrointestinal, hepatic, endocrine, and renal side-effects of anti-PD-1 therapy
-
Hofmann, L., Forschner, A., Loquai, C., et al. Cutaneous, gastrointestinal, hepatic, endocrine, and renal side-effects of anti-PD-1 therapy. Eur J Cancer 60 (2016 Jun), 190–209.
-
(2016)
Eur J Cancer
, vol.60
, pp. 190-209
-
-
Hofmann, L.1
Forschner, A.2
Loquai, C.3
-
17
-
-
84964389238
-
Neurological, respiratory, musculoskeletal, cardiac and ocular side-effects of anti-PD-1 therapy
-
Zimmer, L., Goldinger, S.M., Hofmann, L., et al. Neurological, respiratory, musculoskeletal, cardiac and ocular side-effects of anti-PD-1 therapy. Eur J Cancer 60 (2016 Jun), 210–225.
-
(2016)
Eur J Cancer
, vol.60
, pp. 210-225
-
-
Zimmer, L.1
Goldinger, S.M.2
Hofmann, L.3
-
18
-
-
85011277323
-
Phase III trial (EORTC 18071/CA184-029) of post-operative adjuvant ipilimumab compared to placebo in patients with resected stage III cutaneous melanoma: Health Related Quality of Life (HRQoL) results
-
Coens, C., Suciu, S., Vanna Chiarion-Sileni, V., et al. Phase III trial (EORTC 18071/CA184-029) of post-operative adjuvant ipilimumab compared to placebo in patients with resected stage III cutaneous melanoma: Health Related Quality of Life (HRQoL) results. Lancet Oncol 18:3 (2017 Mar), 393–403.
-
(2017)
Lancet Oncol
, vol.18
, Issue.3
, pp. 393-403
-
-
Coens, C.1
Suciu, S.2
Vanna Chiarion-Sileni, V.3
-
19
-
-
85021091606
-
Three-year pooled analysis of factors associated with clinical outcomes across dabrafenib and trametinib combination therapy phase 3 randomised trials
-
Schadendorf, D., Long, G.V., Stroiakovski, D., et al. Three-year pooled analysis of factors associated with clinical outcomes across dabrafenib and trametinib combination therapy phase 3 randomised trials. Eur J Cancer 82 (2017), 45–55.
-
(2017)
Eur J Cancer
, vol.82
, pp. 45-55
-
-
Schadendorf, D.1
Long, G.V.2
Stroiakovski, D.3
-
20
-
-
0030030347
-
Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group Trial EST 1684
-
Kirkwood, J.M., Strawderman, M.H., Ernstoff, M.S., Smith, T.J., Borden, E.C., Blum, R.H., Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group Trial EST 1684. J Clin Oncol 14:1 (1996 Jan), 7–17.
-
(1996)
J Clin Oncol
, vol.14
, Issue.1
, pp. 7-17
-
-
Kirkwood, J.M.1
Strawderman, M.H.2
Ernstoff, M.S.3
Smith, T.J.4
Borden, E.C.5
Blum, R.H.6
-
21
-
-
7144228601
-
Randomised trial of interferon alpha-2a as adjuvant therapy in resected primary melanoma thicker than 1.5 mm without clinically detectable node metastases. French Cooperative Group on Melanoma
-
Grob, J.J., Dreno, B., de la Salmonière, P., et al. Randomised trial of interferon alpha-2a as adjuvant therapy in resected primary melanoma thicker than 1.5 mm without clinically detectable node metastases. French Cooperative Group on Melanoma. Lancet 351:9120 (1998 Jun 27), 1905–1910.
-
(1998)
Lancet
, vol.351
, Issue.9120
, pp. 1905-1910
-
-
Grob, J.J.1
Dreno, B.2
de la Salmonière, P.3
-
22
-
-
46749103710
-
Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial
-
Eggermont, A.M.M., Suciu, S., Santinami, M., et al. Adjuvant therapy with pegylated interferon alfa-2b versus observation alone in resected stage III melanoma: final results of EORTC 18991, a randomised phase III trial. Lancet 372 (2008), 117–126.
-
(2008)
Lancet
, vol.372
, pp. 117-126
-
-
Eggermont, A.M.M.1
Suciu, S.2
Santinami, M.3
-
23
-
-
84869212118
-
Long term results of the randomized phase III trial EORTC 18991 of adjuvant therapy with pegylated interferon alfa-2b versus observation in resected stage III melanoma
-
Eggermont, A.M., Suciu, S., Testori, A., et al. Long term results of the randomized phase III trial EORTC 18991 of adjuvant therapy with pegylated interferon alfa-2b versus observation in resected stage III melanoma. J Clin Oncol 30 (2012), 3810–3818.
-
(2012)
J Clin Oncol
, vol.30
, pp. 3810-3818
-
-
Eggermont, A.M.1
Suciu, S.2
Testori, A.3
-
24
-
-
25844465690
-
Post-surgery adjuvant therapy with intermediate doses of interferon alfa 2b versus observation in patients with stage IIb/III melanoma (EORTC 18952): randomised controlled trial
-
Eggermont, A.M.M., Suciu, S., MacKie, R., et al. Post-surgery adjuvant therapy with intermediate doses of interferon alfa 2b versus observation in patients with stage IIb/III melanoma (EORTC 18952): randomised controlled trial. Lancet 366 (2005), 1189–1196.
-
(2005)
Lancet
, vol.366
, pp. 1189-1196
-
-
Eggermont, A.M.M.1
Suciu, S.2
MacKie, R.3
-
25
-
-
84655168007
-
Ulceration and stage are predictive of interferon efficacy in melanoma: results of the phase III adjuvant trials EORTC 18952 and EORTC 18991
-
Eggermont, A.M.M., Suciu, S., Testori, A., et al. Ulceration and stage are predictive of interferon efficacy in melanoma: results of the phase III adjuvant trials EORTC 18952 and EORTC 18991. Eur J Cancer 48 (2012), 218–225.
-
(2012)
Eur J Cancer
, vol.48
, pp. 218-225
-
-
Eggermont, A.M.M.1
Suciu, S.2
Testori, A.3
-
26
-
-
84954458766
-
Long term follow up of the EORTC 18952 trial of adjuvant therapy in resected stage IIB-III cutaneous melanoma patients comparing intermediate doses of interferon-alpha-2b (IFN) with observation: ulceration of primary is key determinant for IFN-sensitivity
-
Eggermont, A.M., Suciu, S., Rutkowski, P., et al. Long term follow up of the EORTC 18952 trial of adjuvant therapy in resected stage IIB-III cutaneous melanoma patients comparing intermediate doses of interferon-alpha-2b (IFN) with observation: ulceration of primary is key determinant for IFN-sensitivity. Eur J Cancer 55 (2016), 111–121.
-
(2016)
Eur J Cancer
, vol.55
, pp. 111-121
-
-
Eggermont, A.M.1
Suciu, S.2
Rutkowski, P.3
-
27
-
-
85021715890
-
Adjuvant interferon-α for the treatment of high-risk melanoma: an individual patient data meta-analysis
-
Ives, N.J., Suciu, S., Eggermont, A.M.M., et al. Adjuvant interferon-α for the treatment of high-risk melanoma: an individual patient data meta-analysis. Eur J Cancer 82 (2017), 171–183.
-
(2017)
Eur J Cancer
, vol.82
, pp. 171-183
-
-
Ives, N.J.1
Suciu, S.2
Eggermont, A.M.M.3
-
28
-
-
0041409703
-
Does adjuvant interferon-alpha for high-risk melanoma provide a worthwhile benefit? A meta-analysis of the randomised trials
-
Wheatley, K., Ives, N., Hancock, B., Gore, M., Eggermont, A., Suciu, S., Does adjuvant interferon-alpha for high-risk melanoma provide a worthwhile benefit? A meta-analysis of the randomised trials. Cancer Treat Rev 29 (2003), 241–252.
-
(2003)
Cancer Treat Rev
, vol.29
, pp. 241-252
-
-
Wheatley, K.1
Ives, N.2
Hancock, B.3
Gore, M.4
Eggermont, A.5
Suciu, S.6
-
29
-
-
77950576363
-
Interferon alpha adjuvant therapy in patients with high-risk melanoma: a systematic review and meta-analysis
-
Mocellin, S., Pasquali, S., Rossi, C.R., Nitti, D., Interferon alpha adjuvant therapy in patients with high-risk melanoma: a systematic review and meta-analysis. J Natl Cancer Inst 102 (2010), 493–501.
-
(2010)
J Natl Cancer Inst
, vol.102
, pp. 493-501
-
-
Mocellin, S.1
Pasquali, S.2
Rossi, C.R.3
Nitti, D.4
-
30
-
-
84976328992
-
Diagnosis and treatment of melanoma. European consensus-based interdisciplinary guideline – update 2016
-
Garbe, C., Peris, K., Hauschild, A., et al. Diagnosis and treatment of melanoma. European consensus-based interdisciplinary guideline – update 2016. Eur J Cancer 63 (2016), 201–217.
-
(2016)
Eur J Cancer
, vol.63
, pp. 201-217
-
-
Garbe, C.1
Peris, K.2
Hauschild, A.3
-
31
-
-
84965027970
-
Complete lymph node dissection versus no dissection in patients with sentinel lymph node biopsy positive melanoma (DeCOG-SLT): a multicentre, randomised, phase 3 trial
-
Leiter, U., Stadler, R., Mauch, C., et al. Complete lymph node dissection versus no dissection in patients with sentinel lymph node biopsy positive melanoma (DeCOG-SLT): a multicentre, randomised, phase 3 trial. Lancet Oncol 17:6 (2016), 757–767.
-
(2016)
Lancet Oncol
, vol.17
, Issue.6
, pp. 757-767
-
-
Leiter, U.1
Stadler, R.2
Mauch, C.3
-
32
-
-
85020241826
-
Completion dissection or observation for sentinel-node metastasis in melanoma
-
Faries, M.B., Thompson, J.F., Cochran, A.J., et al. Completion dissection or observation for sentinel-node metastasis in melanoma. N Engl J Med 376:23 (2017), 2211–2222.
-
(2017)
N Engl J Med
, vol.376
, Issue.23
, pp. 2211-2222
-
-
Faries, M.B.1
Thompson, J.F.2
Cochran, A.J.3
-
33
-
-
85051390303
-
(Neo-)adjuvant ipilimumab 1 nivolumab (IPI1NIVO) in palpable stage 3 melanoma – updated relapse free survival (RFS) data from the OpACIN trial and first biomarker analyses
-
Rozeman, E.A., Fanchi, L., van Akkooi, A.C.J., et al. (Neo-)adjuvant ipilimumab 1 nivolumab (IPI1NIVO) in palpable stage 3 melanoma – updated relapse free survival (RFS) data from the OpACIN trial and first biomarker analyses. Ann Oncol, 28(Suppl 5), 2017, 1221.
-
(2017)
Ann Oncol
, vol.28
, pp. 1221
-
-
Rozeman, E.A.1
Fanchi, L.2
van Akkooi, A.C.J.3
-
34
-
-
85030163780
-
Phase 2 study of neoadjuvant dabrafenib + trametinib (D1T) for resectable stage IIIB/C BRAF V600 mutant melanoma
-
Menzies, A.M., Gonzalez, M., Guminski, A., et al. Phase 2 study of neoadjuvant dabrafenib + trametinib (D1T) for resectable stage IIIB/C BRAF V600 mutant melanoma. Ann Oncol, 28(Suppl 5), 2017, 1221.
-
(2017)
Ann Oncol
, vol.28
, pp. 1221
-
-
Menzies, A.M.1
Gonzalez, M.2
Guminski, A.3
-
35
-
-
85024497892
-
Standard-dose pembrolizumab in combination with reduced-dose ipilimumab for patients with advanced melanoma (KEYNOTE-029): an open-label, phase 1b trial
-
Long, G.V., Atkinson, V., Cebon, J.S., et al. Standard-dose pembrolizumab in combination with reduced-dose ipilimumab for patients with advanced melanoma (KEYNOTE-029): an open-label, phase 1b trial. Lancet Oncol 18:9 (2017 Sep), 1202–1210.
-
(2017)
Lancet Oncol
, vol.18
, Issue.9
, pp. 1202-1210
-
-
Long, G.V.1
Atkinson, V.2
Cebon, J.S.3
|