AXL is not essential for Zika virus infection in the mouse brain

Emerging Microbes and Infections

Volumn 6, Issue 3, 2017, Pages

  Li, Feng ^a   Wang, Pei Rong ^b   Qu, Lin Bing ^c   Yi, Chang Hua ^c   Zhang, Fu Chun ^a   Tang, Xiao Ping ^a   Zhang, Li Guo ^b   Chen, Ling ^c  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b INSTITUTE OF BIOPHYSICS   (China)

^c GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AXL RECEPTOR TYROSINE KINASE; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG; ONCOPROTEIN; VIRUS RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONTROLLED STUDY; CRISPR-CAS9 SYSTEM; KNOCKOUT MOUSE; LETTER; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; VIRUS ENCEPHALITIS; VIRUS REPLICATION; VIRUS STRAIN; VIRUS TITRATION; ZIKA FEVER; ANIMAL; BAGG ALBINO MOUSE; BRAIN; GENETICS; HOST PATHOGEN INTERACTION; HUMAN; METABOLISM; PHYSIOLOGY; VIROLOGY; ZIKA VIRUS;

ANIMALS; BRAIN; HOST-PATHOGEN INTERACTIONS; HUMANS; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, VIRUS; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 85030163939     PISSN: None     EISSN: 22221751     Source Type: Journal    
DOI: 10.1038/emi.2017.10     Document Type: Letter

References (5)

1. Mlakar J, Korva M, Tul N et al. Zika virus associated with microcephaly. N Engl J Med 2016; 374: 951-958.
2. Hamel R, Dejarnac O, Wichit S et al. Biology of Zika virus infection in human skin cells. J Virol 2015; 89: 8880-8896.
3. Savidis G, McDougall WM, Meraner P et al. Identification of Zika virus and dengue virus dependency factors using functional genomics. Cell Rep 2016; 16: 232-246.
4. Nowakowski TJ, Pollen AA, Di Lullo E et al. Expression analysis highlights AXL as a candidate Zika virus entry receptor in neural stem cells. Cell Stem Cell 2016; 18: 591-596.
5. Wells MF, Salick MR, Wiskow O et al. Genetic ablation of AXL does not protect human neural progenitor cells and cerebral organoids from zika virus infection. Cell Stem Cell 2016; 19: 703-708.