ArcA overexpression induces fermentation and results in enhanced growth rates of E. coli

Scientific Reports

Volumn 7, Issue 1, 2017, Pages

  Basan, Markus ^a   Hui, Sheng ^b   Williamson, James R ^c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARCA PROTEIN, E COLI; ESCHERICHIA COLI PROTEIN; OUTER MEMBRANE PROTEIN; REPRESSOR PROTEIN;

BIOSYNTHESIS; ESCHERICHIA COLI; FERMENTATION; GENE EXPRESSION REGULATION; GENETICS; GLYCOLYSIS; GROWTH, DEVELOPMENT AND AGING;

BACTERIAL OUTER MEMBRANE PROTEINS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FERMENTATION; GENE EXPRESSION REGULATION, BACTERIAL; GLYCOLYSIS; REPRESSOR PROTEINS;

EID: 85029890926     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-017-12144-6     Document Type: Article

References (20)

1. Gerosa, L., Rijsewijk, B. R. B. H. Van & Christodoulou, D. Pseudo-transition analysis identifies active transcriptional and metabolic regulators that govern bacterial nutrient adaptations. 1-34
2. Schuetz, R., Zamboni, N., Zampieri, M., Heinemann, M. & Sauer, U. Multidimensional optimality of microbial metabolism. Science 336, 601-4 (2012).
3. Basan, M. et al. Overflow metabolism in Escherichia coli results from efficient proteome allocation. Nature 528, 99-104 (2015).
4. Neidhardt, F. C., 1931-, Ingraham, J. L. & Schaechter, M. Physiology of the bacterial cell. (1990).
5. Wolfe, A. J. The acetate switch. Microbiol. Mol. Biol. Rev. 69, 12-50 (2005).
6. De Deken, R. H. The Crabtree Effect: A Regulatory System in Yeast. J. Gen. Microbiol. 44, 149-156 (1966).
7. Vander Heiden, M. G., Cantley, L. C. & Thompson, C. B. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324, 1029-33 (2009).
8. Hanahan, D. & Weinberg, R. A. Hallmarks of cancer: The next generation. Cell 144, 646-674 (2011).
9. Gerosa, L. et al. Pseudo-transition Analysis Identifies the Key Regulators of Dynamic Metabolic Adaptations from Steady-State Data. Cell Syst. 1, 270-282 (2015).
10. Hui, S. et al. Quantitative proteomic analysis reveals a simple strategy of global resource allocation in bacteria. Mol. Syst. Biol. (2015).
11. Klumpp, S., Zhang, Z. & Hwa, T. Growth rate-dependent global effects on gene expression in bacteria. Cell 139, 1366-75 (2009).
12. Alvarez, A. F. & Georgellis, D. In vitro and in vivo analysis of the ArcB/A redox signaling pathway. Methods Enzymol. 471, 205-28 (2010).
13. Brown, S. D. & Jun, S. Complete Genome Sequence of Escherichia coli NCM3722. Genome Announc. 3 (2015).
14. Grenier, F., Matteau, D., Baby, V. & Rodrigue, S. Complete Genome Sequence of Escherichia coli BW25113. Genome Announc. 2 (2014).
15. Applebee, M. K., Joyce, A. R., Conrad, T. M., Pettigrew, D. W. & Palsson, B. Ø. Functional and metabolic effects of adaptive glycerol kinase (GLPK) mutants in Escherichia coli. J. Biol. Chem. 286, 23150-9 (2011).
16. Towbin, B. D. et al. Optimality and sub-optimality in a bacterial growth law. Nat. Commun. 8, 14123 (2017).
17. Cortay, J. C. et al. In vitro asymmetric binding of the pleiotropic regulatory protein, FruR, to the ace operator controlling glyoxylate shunt enzyme synthesis. J. Biol. Chem. 269, 14885-91 (1994).
18. Ramseier, T. M. Cra and the control of carbon flux via metabolic pathways. Res. Microbiol. 147, 489-93 (1996).
19. Kotte, O., Volkmer, B., Radzikowski, J. L. & Heinemann, M. Phenotypic bistability in Escherichia coli's central carbon metabolism. Mol. Syst. Biol. 10, 736 (2014).
20. Malpica, R., Franco, B., Rodriguez, C., Kwon, O. & Georgellis, D. Identification of a quinone-sensitive redox switch in the ArcB sensor kinase. Proc. Natl. Acad. Sci. USA. 101, 13318-13323 (2004).