Mood stabilizers in pregnancy and child developmental outcomes: A systematic review

Australian and New Zealand Journal of Psychiatry

Volumn 51, Issue 11, 2017, Pages 1087-1097

  Haskey, Carolyn ^a   Galbally, Megan ^b,c,d  

^a Peel and Rockingham Kwinana Mental Health Service   (Australia)

^b MURDOCH UNIVERSITY   (Australia)

^c UNIVERSITY OF NOTRE DAME   (Australia)

^d FIONA STANLEY HOSPITAL   (Australia)

Author keywords

bipolar affective disorder; child development; mood stabilizers; Pregnancy

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; LAMOTRIGINE; LITHIUM CARBONATE; MOOD STABILIZER; VALPROIC ACID; NEUROLEPTIC AGENT; TRANQUILIZER;

ADAPTIVE BEHAVIOR; BIPOLAR DISORDER; CHILD; CHILD DEVELOPMENT; COGNITION; COMPARATIVE STUDY; DISEASE ASSOCIATION; DOSE RESPONSE; DRUG CHOICE; DRUG EFFECT; ELECTRONIC MEDICAL RECORD; FEMALE; FETUS OUTCOME; FOLLOW UP; HUMAN; MENTAL DISEASE; NERVOUS SYSTEM DEVELOPMENT; PREGNANCY; PREGNANCY OUTCOME; PREGNANT WOMAN; PRENATAL EXPOSURE; REVIEW; RISK; SYSTEMATIC REVIEW; CHEMICALLY INDUCED;

ANTICONVULSANTS; ANTIMANIC AGENTS; ANTIPSYCHOTIC AGENTS; BIPOLAR DISORDER; CHILD; CHILD DEVELOPMENT; FEMALE; HUMANS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS;

EID: 85029793114     PISSN: 00048674     EISSN: 14401614     Source Type: Journal    
DOI: 10.1177/0004867417726175     Document Type: Review

References (41)

1. Arkilo D, Hanna J, Dickens D. (2015) Pregnancy and neurodevelopmental outcomes with in-utero antiepileptic agent exposure. A pilot study. European Journal of Paediatric Neurology 19: 37–40.
2. Baker GA, Bromley RL, Briggs M. (2015) IQ at 6 years after in utero exposure to antiepileptic drugs: A controlled cohort study. Neurology 84: 382–390.
3. Bambini-Junior V, Rodrigues L, Behr GA. (2011) Animal model of autism induced by prenatal exposure to valproate: Behavioral changes and liver parameters. Brain Research 1408: 8–16.
4. Bayley N, (2005) Bayley Scales of Infant and Toddler Development, 3rd Edition. San Antonio, TX: Psychological Corporation.
5. Bergink V, Burgerhout KM, Koorengevel KM. (2015) Treatment of psychosis and mania in the postpartum period. American Journal of Psychiatry 172: 115–123.
6. Brameld KJ, Jablensky A, Griffith J. (2017) Psychotropic medication and substance use during pregnancy by women with severe mental illness. Frontiers in Psychiatry 8: 28.
7. Bromley R, (2016) The treatment of epilepsy in pregnancy: The neurodevelopmental risks associated with exposure to antiepileptic drugs. Reproductive Toxicology 64: 203–210.
8. Bromley RL, Calderbank R, Cheyne CP. (2016) Cognition in school-age children exposed to levetiracetam, topiramate, or sodium valproate. Neurology 87: 1943–1953.
9. Bromley RL, Pulman JL, Adab N. (2014) Meta-analysis of neurodevelopmental outcome following prenatal exposure to antiepileptic drugs. Epilepsia 55: 31.
10. Deshmukh U, Adams J, Macklin EA. (2016) Behavioral outcomes in children exposed prenatally to lamotrigine, valproate, or carbamazepine. Neurotoxicology and Teratology 54: 5–14.
11. Elkjaer LS, Bech BH, Laursen TM. (2016) Cognitive problems among children exposed to antiepileptic drugs preliminary data. European Journal of Neurology 23: 26.
12. Eriksen HL, Kesmodel US, Underbjerg M. (2013) Predictors of intelligence at the age of 5: Family, pregnancy and birth characteristics, postnatal influences, and postnatal growth. PLoS ONE 8: e79200.
13. Forsberg L, Berglund G, Naver L. (2012) Bipolar disorder and pregnancy-neurodevelopmental outcome of children exposed to maternal illness with or without lithium during pregnancy. Archives of Disease in Childhood 97: A184–A185.
14. Galbally M, Lewis AJ, Buist A, (2015) Child developmental outcomes in preschool children following antidepressant exposure in pregnancy. Australian and New Zealand Journal of Psychiatry 49: 642–650.
15. Galbally M, Lewis AJ, Gentile S. (2012) The biology of fetal exposure to serotonin reuptake inhibitors: Implications for neurodevelopment. In: Migne LJ, Post JW, (eds) Antidepressants: Pharmacology, Health Effects and Controversy. New York: Nova Science Publishers, pp. 1–26.
16. Galbally M, Roberts M, Buist A, (2010a) Mood stabilizers in pregnancy: A systematic review. Australian and New Zealand Journal of Psychiatry 44: 967–977.
17. Galbally M, Snellen M, Walker S. (2010b) Management of antipsychotic and mood stabilizer medication in pregnancy: Recommendations for antenatal care. Australian and New Zealand Journal of Psychiatry 44: 99–108.
18. Gentile S, (2012) Lithium in pregnancy: The need to treat, the duty to ensure safety. Expert Opinion on Drug Safety 11: 425–437.
19. Gogatishvili N, Ediberidze T, Mamukadze S. (2015) Cognitive outcomes of children with fetal antiepileptic drug exposure at the age of 3–6 years-preliminary data. European Journal of Neurology 22: 329.
20. Gopinath N, Muneer AK, Unnikrishnan S. (2015) Children (10–12 years age) of women with epilepsy have lower intelligence, attention and memory: Observations from a prospective cohort case control study. Epilepsy Research 117: 58–62.
21. Guveli BT, Gurses C, Atakli D. (2015) Behavioral characteristics and cognitive development among school age children born to women with epilepsy. Neurological Research 37: 295–300.
22. Johnson KC, LaPrairie JL, Brennan PA. (2012) Prenatal antipsychotic exposure and neuromotor performance during infancy. JAMA Psychiatry 69: 787–794.
23. Judd F, Komiti A, Sheehan P. (2014) Adverse obstetric and neonatal outcomes in women with severe mental illness: To what extent can they be prevented? Schizophrenia Research 157: 305–309.
24. Khan SJ, Fersh ME, Ernst C. (2016) Bipolar disorder in pregnancy and postpartum: Principles of management. Current Psychiatry Reports 18: 13.
25. Kulkarni J, Worsley R, Gilbert H. (2014) A prospective cohort study of antipsychotic medications in pregnancy: The first 147 pregnancies and 100 one year old babies. PLoS ONE 9: e94788.
26. Malhi GS, Bassett D, Boyce P. (2015) Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders. Australian and New Zealand Journal of Psychiatry 49: 1087–1206.
27. Marcon C, Geniaux H, Coubret A. (2015) Child psychomotor development after in utero exposure to an antiepileptic drug monotherapy. Fundamental and Clinical Pharmacology 29: 4.
28. McCorry D, Bromley R, (2015) Does in utero exposure of antiepileptic drugs lead to failure to reach full cognitive potential? Seizure 28: 51–56.
29. Meador KJ, Loring DW, (2016) Developmental effects of antiepileptic drugs and the need for improved regulations. Neurology 86: 297–306.
30. Moher D, Liberati A, Tetzlaff J. (2009) Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. PLoS Med 6: e1000097.
31. Nguyen T, Faulkner D, Frayne J. (2012) Obstetric and neonatal outcomes of pregnant women with severe mental illness at a specialist antenatal clinic. Medical Journal of Australia 199: S26–S29.
32. Peng M, Gao K, Ding Y. (2013) Effects of prenatal exposure to atypical antipsychotics on postnatal development and growth of infants: A case-controlled, prospective study. Psychopharmacology 228: 577–584.
33. Schou M, (1976) What happened later to the lithium babies? A follow up study of children born without malformations. Acta Psychiatrica Scandinavica 54: 193–197.
34. Shao P, Ou J, Peng M. (2015) Effects of clozapine and other atypical antipsychotics on infants development who were exposed to as fetus: A post-hoc analysis. PLoS ONE 10: e0123373.
35. Tomson T, Marson A, Boon P. (2015) Valproate in the treatment of epilepsy in girls and women of childbearing potential. Epilepsia 56: 1006–1019.
36. Van der Lugt N, Van de Maat JS, Van Kamp IL. (2012) Fetal, neonatal and developmental outcomes of lithium-exposed pregnancies. Early Human Development 88: 375–378.
37. Viguera AC, Nonacs R, Cohen LS. (2000) Risk of recurrence of bipolar disorder in pregnant and nonpregnant women after discontinuing lithium maintenance. American Journal of Psychiatry 157: 179–184.
38. Wechsler D, (1949) Wechsler Intelligence Scale for Children. San Antonio, TX: Psychological Corporation Wechsler Intelligence Scale for Children.
39. Wells G, Shea B, O’Connell T. (2014) Newcastle–Ottawa Quality Assessment Scale cohort studies. Available at: www.ohri.ca/programs/clinical_epidemiology/oxford.asp (accessed 15 September 2016).
40. Wesseloo R, Kamperman AM, Munk-Olsen T. (2016) Risk of postpartum relapse in bipolar disorder and postpartum psychosis: A systematic review and meta-analysis. American Journal of Psychiatry 173: 117–127.
41. Wood AG, Nadebaum C, Anderson V. (2015) Prospective assessment of autism traits in children exposed to antiepileptic drugs during pregnancy. Epilepsia 56: 1047–1055.