Scientific Opinion on the substantiation of health claims related to selenium and protection of DNA, proteins and lipids from oxidative damage (ID 277, 283, 286, 1289, 1290, 1291, 1293, 1751), function of the immune system (ID 278), thyroid function (ID 279, 282, 286, 1289, 1290, 1291, 1293), function of the heart and blood vessels (ID 280), prostate function (ID 284), cognitive function (ID 285) and spermatogenesis (ID 396) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

EFSA Journal

Volumn 7, Issue 10, 2009, Pages

[No Author Info available]

Author keywords

antioxidant; cardiovascular; cognitive; health claims; immune system; iodine utilisation; minerals; prostate; Selenium; spermatogenesis; thyroid hormone

Indexed keywords

EID: 85029285091     PISSN: None     EISSN: 18314732     Source Type: Journal    
DOI: 10.2903/j.efsa.2009.1220     Document Type: Article

References (19)

1. Ansari MA, Ahmad AS, Ahmad M, Salim S, Yousuf S, Ishrat T, Islam F, 2004. Selenium protects cerebral ischemia in rat brain mitochondria. Biol. Trace Elem. Res. 101, 73–86.
2. Bates CJ, 2005. Selenium. In: Caballero B, Allen L, Prentice A (eds). Encyclopedia of Human Nutrition. 2nd ed. Elsevier Academic Press, 118–125.
3. Burk RF and Levander OA, 2006. Selenium. In: Shils ME, Shike M, Ross AC, Caballero B, Cousins RJ (eds). Modern nutrition in health and disease, 10th edition. Philadelphia: Lippincott Williams and Wilkins, 326–331.
4. Chen J and Berry MJ, 2003. Selenium and selenoproteins in the brain and brain diseases. J. Neurochem. 86, 1–12.
5. Combs GF, 2005. Current evidence and research needs to support a health claim for selenium and cancer prevention. J. Nutr. 135, 343–347.
6. Dalla Puppa L, Savaskan NE, Brauer AU, Behne D, Kyriakopoulos A, 2007. The role of selenite on microglial migration. Ann. N.Y. Acad. Sci. 1096, 179–183.
7. Flores-Mateo G, Navas-Acien A, Pastor-Barriuso R, Guallar E, 2006. Selenium and coronary heart disease: a meta-analysis. Am. J. Clin. Nutr. 84, 762–773.
8. Gupta S, 2007. Prostate cancer chemoprevention: current status and future prospects. Toxicol. Appl. Pharmacol. 224, 369–376.
9. IoM (Institute of Medicine), 2001. Dietary Reference Intakes for vitamin C, vitamin E, selenium, and carotenoids. Washington D.C., National Academy Press.
10. Kryukov GV, Castellano S, Novoselov SV, Lobanov AV, Zehtab O, Guigó R, Gladyshev VN, 2003. Characterization of Mammalian Selenoproteomes. Science 300, 1439–1443.
11. Kuiper GG, Kester MH, Peeters RP, Visser TJ, 2005. Biochemical mechanisms of thyroid hormone deiodination. Thyroid 15, 787–798.
12. Lippman SM, Klein EA, Goodman PJ, Lucia MS, Thompson IM, Ford LG, Parnes HL, Minasian LM, Gaziano JM, Hartline JA, Parsons JK, Bearden JD, Crawford ED, Goodman GE, Claudio J, Winquist E, Cook ED, Karp DD, Walther P, Lieber MM, Kristal AR, Darke AK, Arnold KB, Ganz PA, Santella RM, Albanes D, Taylor PR, Probstfield JL, Jagpal TJ, Crowley JJ, Meyskens FL, Baker LH, Coltman CA, 2009. Effect of Selenium and Vitamin E on Risk of Prostate Cancer and Other Cancers: The Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA 301, 39–51.
13. Papp LV, Lu J, Holmgren A, Khanna KK, 2007. From selenium to selenoproteins: synthesis, identity, and their role in human health. Antioxid. Redox Signal. 9, 775–806.
14. Peters U, Foster CB, Chatterjee N, Schatzkin A, Reding D, Andriole GL, Crawford ED, Sturup S, Chanock SJ, Hayes RB, 2007. Serum selenium and risk of prostate cancer-a nested case-control study. Am. J. Clin. Nutr. 85, 209–217.
15. SCF (Scientific Committee on Food), 2000. Opinion of the Scientific Committee on Food on the Tolerable Upper Intake Level of Selenium.
16. Schweizer U, Brauer AU, Kohrle J, Nitsch R, Savaskan NE, 2004. Selenium and brain function: a poorly recognized liaison. Brain Res. Rev. 45, 164–178.
17. Thomson CD, 2004. Assessment of requirements for selenium and adequacy of selenium status: a review. Eur. J. Clin. Nutr. 58, 391–402.
18. Xu GL, Wang SC, Gu BQ, Yang YX, Song HB, Xue WL, Liang WS, Zhang PY, 1997. Further investigation on the role of selenium deficiency in the aetiology and pathogenesis of Keshan disease. Biomed. Environ. Sci. 10, 316–326.
19. Yousuf S, Atif F, Ahmad M, Hoda MN, Khan MB, Ishrat T, Islam F, 2007. Selenium plays a modulatory role against cerebral ischemia-induced neuronal damage in rat hippocampus. Brain Res. 1147, 218–225.