Formaldehyde Hemiacetal Sampling, Recovery, and Quantification from Electronic Cigarette Aerosols

Scientific Reports

Volumn 7, Issue 1, 2017, Pages

  Salamanca, James C ^a   Munhenzva, Ian ^a   Escobedo, Jorge O ^a   Jensen, R Paul ^a   Shaw, Angela ^a   Campbell, Robert ^a   Luo, Wentai ^a   Peyton, David H ^a   Strongin, Robert M ^a  

^a PORTLAND STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FORMALDEHYDE;

AEROSOL; ANALOGS AND DERIVATIVES; CHEMISTRY; ELECTRONIC CIGARETTE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

AEROSOLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTRONIC NICOTINE DELIVERY SYSTEMS; FORMALDEHYDE; MAGNETIC RESONANCE SPECTROSCOPY;

EID: 85028966693     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-017-11499-0     Document Type: Article

References (25)

1. The health consequences of smoking-50 years of progress: A report of the Surgeon General. (US Department of Health Human Services, Atlanta, GA, 2014).
2. Geiss, O., Bianchi, I. & Barrero-Moreno, J. Correlation of volatile carbonyl yields emitted by e-cigarettes with the temperature of the heating coil and the perceived sensorial quality of the generated vapours. Int. J. Hyg. Environ. Health 219, 268-277 (2016).
3. Ogunwale, M. A. et al. Aldehyde detection in electronic cigarette aerosols. ACS omega 2, 1207-1214 (2017).
4. Goniewicz, M. L. et al. Levels of selected carcinogens and toxicants in vapour from electronic cigarettes. Tob. Control 23, 133-139 (2014).
5. Cheng, T. Chemical evaluation of electronic cigarettes. Tob. Control 23, ii11-ii17 (2014).
6. Jensen, R. P., Luo, W., Pankow, J. F., Strongin, R. M. & Peyton, D. H. Hidden formaldehyde in e-cigarette aerosols. N. Engl. J. Med. 2015, 392-394 (2015).
7. Kosmider, L. et al. Carbonyl Compounds in Electronic Cigarette Vapors: Effects of Nicotine Solvent and Battery Output Voltage. Nicotine Tob. Res. 16, 1319-1326 (2014).
8. Jensen, R. P., Strongin, R. M. & Peyton, D. H. Solvent Chemistry in the Electronic Cigarette Reaction Vessel. Sci Rep 7, 42549 (2017).
9. Bekki, K. et al. Carbonyl compounds generated from electronic cigarettes. Int. J. Environ. Res. Public. Health 11, 11192-11200 (2014).
10. Sleiman, M. et al. Emissions from electronic cigarettes: Key parameters affecting the release of harmful chemicals. Environ. Sci. Technol. 50, 9644-9651 (2016).
11. Khlystov, A. & Samburova, V. Flavoring compounds dominate toxic aldehyde production during e-cigarette vaping. Environ. Sci. Technol. 50, 13080-13085 (2016).
12. Soussy, S. et al. Detection of 5-hydroxymethylfurfural and furfural in the aerosol of electronic cigarettes. Tob. Control, tobaccocontrol-2016-053220, (2016).
13. Tayyarah, R. & Long, G. A. Comparison of select analytes in aerosol from e-cigarettes with smoke from conventional cigarettes and with ambient air. Regul. Toxicol. Pharmacol. 70, 704-710 (2014).
14. Hutzler, C. et al. Chemical hazards present in liquids and vapors of electronic cigarettes. Arch. Toxicol. 88, 1295-1308 (2014).
15. Pankow, J. F. Calculating compound dependent gas-droplet distributions in aerosols of propylene glycol and glycerol from electronic cigarettes. J. Aerosol Sci. 107, 9-13 (2017).
16. Farsalinos, K. E., Voudris, V. & Poulas, K. Ecigarettes generate high levels of aldehydes only in 'dry puff'conditions. Addiction 110, 1352-1356 (2015).
17. Balashov, A., Danov, S., Krasnov, V., Chernov, A. Y. & Ryabova, T. Association of formaldehyde in aqueous-Alcoholic systems. Russ. J. Gen. Chem. 72, 744-747 (2002).
18. CORESTA Smoke Science Study Group: CORESTA recommended method No. 74: Determination of selected carbonyls in mainstream smoke by HPLC, http://www.coresta.org/Recommended-Methods/CRM-74-update(July14).pdf (2014).
19. Bharti, S. K. & Roy, R. Quantitative 1H NMR spectroscopy. Trends Anal. Chem.; TrAC 35, 5-26 (2012).
20. Paine, J. B., Pithawalla, Y. B., Naworal, J. D. & Thomas, C. E. Carbohydrate pyrolysis mechanisms from isotopic labeling: Part 1: The pyrolysis of glycerin: Discovery of competing fragmentation mechanisms affording acetaldehyde and formaldehyde and the implications for carbohydrate pyrolysis. J. Anal. Appl. Pyrolysis 80, 297-311 (2007).
21. Nef, J. U. Dissociation processes in the glycol-glycerine sequence. Justus Liebigs Ann. Chem. 335, 191-245 (1904).
22. Harnitzky, T. & Menschutkine, N. Ann. Chem. Pharm. 136, 126, (1865).
23. Schulz, M. & Tollens, B. Justus Liebigs Ann. Chem., 20 (1896).
24. Trillat, A. & Cambier, R. Action of paraformaldehyde (trioxymethylene) on alcohols in presence of ferric chloride. Compt. Rend. 118, 1277-1280 (1894).
25. Walker, J. F. Formaldehyde. 3rd edn, Vol. 159 (American Chemical Society Monograph Series; Robert E. Krieger Publishing Company, 1975).