Inflammatory myopathy associated with anti-mitochondrial antibodies: A distinct phenotype with cardiac involvement

Seminars in Arthritis and Rheumatism

Volumn 47, Issue 4, 2018, Pages 552-556

  Albayda, Jemima ^a   Khan, Aamna ^a   Casciola Rosen, Livia ^a   Corse, Andrea M ^a   Paik, Julie J ^a   Christopher Stine, Lisa ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Anti mitochondrial antibodies; Arrhythmia; Cardiomyopathy; Myocarditis; Myositis

Indexed keywords

MITOCHONDRION ANTIBODY; AUTOANTIBODY;

ADULT; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNE HEPATITIS; BOHAN AND PETER CRITERIA; CARDIOMYOPATHY; CLINICAL ASSESSMENT TOOL; CLINICAL FEATURE; COHORT ANALYSIS; CONTROLLED STUDY; DERMATOMYOSITIS; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; ELECTROPHYSIOLOGY; FEMALE; GRANULOMATOUS MYOSITIS; HASHIMOTO DISEASE; HEART ATRIUM ARRHYTHMIA; HEART BLOCK; HEART DISEASE; HEART VENTRICLE ARRHYTHMIA; HEART VENTRICLE FIBRILLATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNEMEDIATED NECROTIZING MYOPATHY; IMMUNOPATHOGENESIS; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; MUSCLE ATROPHY; MUSCLE BIOPSY; MYOCARDITIS; MYOSITIS; PHENOTYPE; POLYMYOSITIS; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCAPLAR WINGING; SUPRAVENTRICULAR TACHYCARDIA; WEAKNESS; CARDIAC MUSCLE; IMMUNOLOGY; MIDDLE AGED; MITOCHONDRION;

AUTOANTIBODIES; FEMALE; HUMANS; MALE; MIDDLE AGED; MITOCHONDRIA; MYOCARDIUM; MYOSITIS; PHENOTYPE; RETROSPECTIVE STUDIES;

EID: 85028861937     PISSN: 00490172     EISSN: 1532866X     Source Type: Journal    
DOI: 10.1016/j.semarthrit.2017.06.004     Document Type: Article

References (38)

1. Tansley, S., Gunawardena, H., The evolving spectrum of polymyositis and dermatomyositis—moving towards clinicoserological syndromes: a critical review. Clin Rev Allergy Immunol 47 (2014), 264–273, 10.1007/s12016-013-8387-6.
2. Betteridge, Z., McHugh, N., Myositis-specific autoantibodies: an important tool to support diagnosis of myositis. n/a-n/a J Intern Med, 2015, 10.1111/joim.12451.
3. Satoh, M., Tanaka, S., Ceribelli, A., Calise, S.J., Chan, E.K.L., A comprehensive overview on myositis-specific antibodies: new and old biomarkers in idiopathic inflammatory myopathy. Clin Rev Allergy Immunol 52 (2017), 1–19, 10.1007/s12016-015-8510-y.
4. Fiorentino, D., Chung, L., Zwerner, J., Rosen, A., Casciola-Rosen, L., The mucocutaneous and systemic phenotype of dermatomyositis patients with antibodies to MDA5 (CADM-140): a retrospective study. J Am Acad Dermatol 65 (2011), 25–34, 10.1016/j.jaad.2010.09.016.
5. Imbert-Masseau, A., Hamidou, M., Agard, C., Grolleau, J.-Y., Chérin, P., Antisynthetase syndrome. Joint Bone Spine 70 (2003), 161–168, 10.1016/S1297-319X(03)00012-5.
6. Bauhammer, J., Blank, N., Max, R., Lorenz, H.-M., Wagner, U., Krause, D., et al. Rituximab in the treatment of Jo1 antibody-associated antisynthetase syndrome: anti-Ro52 positivity as a marker for severity and treatment response. J Rheumatol 43 (2016), 1566–1574 jrheum–150844.
7. Hu, C.-J., Primary biliary cirrhosis: What do autoantibodies tell us?. World J Gastroenterol, 16, 2010, 3616, 10.3748/wjg.v16.i29.3616.
8. Chantran, Y., Ballot, É., Johanet, C., Autoantibodies in primary biliary cirrhosis: antimitochondrial autoantibodies. Clin Res Hepatol Gastroenterol 37 (2013), 431–433, 10.1016/j.clinre.2013.05.002.
9. Dahlqvist, G., Gaouar, F., Carrat, F., Meurisse, S., Chazouillères, O., Poupon, R., et al. Large-scale characterization study of patients with antimitochondrial antibodies but nonestablished primary biliary cholangitis. Hepatology 65 (2017), 152–163.
10. Floreani, A., Franceschet, I., Cazzagon, N., Spinazzè A., Buja, A., Furlan, P., et al. Extrahepatic autoimmune conditions associated with primary biliary cirrhosis. Clin Rev Allergy Immunol 48 (2015), 192–197, 10.1007/s12016-014-8427-x.
11. Paik, J.J., Wigley, F.M., Lloyd, T.E., Corse, A.M., Casciola-Rosen, L., Shah, A.A., et al. Spectrum of muscle histopathologic findings in forty-two scleroderma patients with weakness: muscle histopathologic findings in SSc patients with weakness. Arthritis Care Res 67 (2015), 1416–1425, 10.1002/acr.22620.
12. Bohan, A., Peter, J.B., Polymyositis and dermatomyositis (first of two parts). N Engl J Med 292 (1975), 344–347, 10.1056/NEJM197502132920706.
13. Bohan, A., Peter, J.B., Polymyositis and dermatomyositis (second of two parts). N Engl J Med 292 (1975), 403–407, 10.1056/NEJM197502202920807.
14. Hoogendijk, J.E., Amato, A.A., Lecky, B.R., Choy, E.H., Lundberg, I.E., Rose, M.R., et al. 119th ENMC International Workshop: trial design in adult idiopathic inflammatory myopathies, with the exception of inclusion body myositis, 10–12 October 2003, Naarden, The Netherlands. Neuromuscul Disord 14 (2004), 337–345, 10.1016/j.nmd.2004.02.006.
15. Pamfil, C., Candrea, E., Berki, E., Popov, H., Radu, P., Rednic, S., Primary biliary cirrhosis - autoimmune hepatitis overlap syndrome associated with dermatomyositis, autoimmune thyroiditis and antiphospholipid syndrome. J Gastrointestin Liver Dis, 24, 2015, 10.15403/jgld.2014.1121.cpa.
16. Willson, R.A., Therapeutic quandary. Dig Dis Sci 26 (1981), 372–375.
17. Yasuda, Y., Nakano, S., Akiguchi, I., Tanaka, M., Kameyama, M., Polymyositis associated with asymptomatic primary biliary cirrhosis. Eur Neurol 33 (1993), 51–53.
18. Harada, N., Dohmen, K., Itoh, H., Ohshima, T., Yamamoto, H., Nagano, M., et al. Sibling cases of primary biliary cirrhosis associated with polymyositis, vasculitis and Hashimoto's thyroiditis. Intern Med 31 (1992), 289–293.
19. Uenaka, T., Kowa, H., Sekiguchi, K., Nagata, K., Ohtsuka, Y., Kanda, F., et al. Myositis with antimitochondrial antibodies diagnosed by rectus abdominis muscle biopsy: myopathy with anti-M2 antibodies. Muscle Nerve 47 (2013), 766–768, 10.1002/mus.23730.
20. Tanaka, K., Sato, A., Kasuga, K., Kanazawa, M., Yanagawa, K., Umeda, M., et al. Chronic myositis with cardiomyopathy and respiratory failure associated with mild form of organ-specific autoimmune diseases. Clin Rheumatol 26 (2007), 1917–1919, 10.1007/s10067-007-0698-7.
21. Simpson, W.G., Nickl, N.J., Polymyositis associated with primary biliary cirrhosis. J Ky Med Assoc 93 (1995), 93–94.
22. Milosevic, M., Adams, P., Primary biliary cirrhosis and polymyositis. J Clin Gastroenterol 12 (1990), 332–335.
23. Matsumoto, K., Tanaka, H., Yamana, S., Kaneko, A., Tsuji, T., Ryo, K., et al. Successful steroid therapy for heart failure due to myocarditis associated with primary biliary cirrhosis. Can J Cardiol 28 (2012), 515.e3–515.e6, 10.1016/j.cjca.2011.12.010.
24. Kurihara, Y., Shishido, T., Oku, K., Takamatsu, M., Ishiguro, H., Suzuki, A., et al. Polymyositis associated with autoimmune hepatitis, primary biliary cirrhosis, and autoimmune thrombocytopenic purpura. Mod Rheumatol 21 (2011), 325–329, 10.1007/s10165-010-0397-0.
25. Honma, F., Shio, K., Monoe, K., Kanno, Y., Takahashi, A., Yokokawa, J., et al. Primary biliary cirrhosis complicated by polymyositis and pulmonary hypertension. Intern Med 47 (2008), 667–669.
26. Epstein, O., Burroughs, A.K., Sherlock, S., Polymyositis and acute onset systemic sclerosis in a patient with primary biliary cirrhosis: a clinical syndrome similar to the mixed connective tissue disease. J R Soc Med, 74, 1981, 456.
27. Bradley, J.D., Pinals, R.S., Gupta, R.C., Chronic active hepatitis associated with polymyositis. Association with precipitating mitochondrial M-B antibody. J Rheumatol 12 (1985), 368–371.
28. Bondeson, J., Veress, B., Lindroth, Y., Lindgren, S., Polymyositis associated with asymptomatic primary biliary cirrhosis. Clin Exp Rheumatol 16 (1998), 172–174.
29. Boki, K.A., Dourakis, S.P., Polymyositis associated with primary biliary cirrhosis. Clin Rheumatol 14 (1995), 375–378.
30. Mader, R., Blake, R., Keystone, E.C., Polymyositis associated with primary biliary cirrhosis. J Rheumatol 18 (1991), 1767–1768.
31. Varga, J., Heiman-Patterson, T., Muñoz, S., Love, L.A., Myopathy with mitochondrial alterations in patients with primary biliary cirrhosis and antimitochondrial antibodies. Arthritis Rheum 36 (1993), 1468–1475.
32. Tanaka, T., Suzuki, S., Nishino, I., Hamaguchi, Y., Fujimoto, T., What is the third serological marker associated with immune-mediated necrotizing myopathy?. Scand J Rheumatol, 2017, 1–2, 10.1080/03009742.2016.1258730.
33. Maeda, M.H., Tsuji, S., Shimizu, J., Inflammatory myopathies associated with anti-mitochondrial antibodies. Brain 135 (2012), 1767–1777, 10.1093/brain/aws106.
34. Kassardjian, C.D., Lennon, V.A., Alfugham, N.B., Mahler, M., Milone, M., Clinical features and treatment outcomes of necrotizing autoimmune myopathy. JAMA Neurol, 72, 2015, 996, 10.1001/jamaneurol.2015.1207.
35. Dieval, C., Deligny, C., Meyer, A., Cluzel, P., Champtiaux, N., Lefevre, G., et al. Myocarditis in patients with antisynthetase syndrome: prevalence, presentation, and outcomes. Medicine (Baltimore), 94, 2015, e798, 10.1097/MD.0000000000000798.
36. Schultheiss, H.P., Bolte, H.D., Immunological analysis of auto-antibodies against the adenine nucleotide translocator in dilated cardiomyopathy. J Mol Cell Cardiol 17 (1985), 603–617, 10.1016/S0022-2828(85)80029-8.
37. Schulze, K., Becker, B.F., Schultheiss, H.P., Antibodies to the ADP/ATP carrier, an autoantigen in myocarditis and dilated cardiomyopathy, penetrate into myocardial cells and disturb energy metabolism in vivo. Circ Res 64 (1989), 179–192.
38. Schulze, K., Becker, B.F., Schauer, R., Schultheiss, H.P., Antibodies to ADP-ATP carrier—an autoantigen in myocarditis and dilated cardiomyopathy—impair cardiac function. Circulation 81 (1990), 959–969.