Conditional Müller cell ablation leads to retinal iron accumulation

Investigative Ophthalmology and Visual Science

Volumn 58, Issue 10, 2017, Pages 4223-4234

  Baumann, Bailey ^a   Sterling, Jacob ^a   Song, Ying ^a   Song, Delu ^a   Fruttiger, Marcus ^b   Gillies, Mark ^c   Shen, Weiyong ^c   Dunaief, Joshua L ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

AMD; Blood retinal barrier; Diabetic retinopathy; Ferroportin; Iron; Macular telangectasia type 2; M ller cells; Retina; Zip14; Zip8

Indexed keywords

BETA ACTIN; FERRITIN; FERROPORTIN; TRANSFERRIN RECEPTOR; ZINC TRANSPORTER; CATION TRANSPORT PROTEIN; IRON; MESSENGER RNA; METAL TRANSPORTING PROTEIN 1; SLC39A14 PROTEIN, MOUSE; SLC39A8 PROTEIN, MOUSE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD RETINA BARRIER; CELL LOSS; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; MASS SPECTROMETRY; MOUSE; MUELLER CELL; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RETINAL IRON ACCUMULATION; RETINOPATHY; TELANGIECTASIA; WESTERN BLOTTING; AGED; ANIMAL; C57BL MOUSE; CAPILLARY PERMEABILITY; CBA MOUSE; DISEASE MODEL; FEMALE; GENETICS; MACROGLIA; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; RETINA; RETINAL TELANGIECTASIA; TRANSGENIC MOUSE;

AGED; ANIMALS; BLOOD-RETINAL BARRIER; BLOTTING, WESTERN; CAPILLARY PERMEABILITY; CATION TRANSPORT PROTEINS; DISEASE MODELS, ANIMAL; EPENDYMOGLIAL CELLS; FEMALE; FERRITINS; HUMANS; IMMUNOHISTOCHEMISTRY; IRON; MALE; MASS SPECTROMETRY; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, TRANSGENIC; MIDDLE AGED; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, TRANSFERRIN; RETINA; RETINAL TELANGIECTASIS; RNA, MESSENGER;

EID: 85028608584     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.17-21743     Document Type: Article

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