Nonalcoholic Fatty Liver Disease and Coronary Artery Calcification in a Northern Chinese Population: A Cross Sectional Study

Scientific Reports

Volumn 7, Issue 1, 2017, Pages

  Wu, Rina ^a   Hou, Feng ^b   Wang, Xiaomin ^a   Zhou, Yong ^c   Sun, Kai ^a   Wang, Youxin ^d   Liu, Henghui ^e   Wu, Jing ^e   Zhao, Ruiping ^a   Hu, Jiang ^a  

^a Central Hospital of Baotou   (China)

^b INNER MONGOLIA MEDICAL UNIVERSITY   (China)

^c CAPITAL MEDICAL UNIVERSITY   (China)

^d CAPITAL MEDICAL UNIVERSITY   (China)

^e Beijing Success Technology Co Ltd   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; BLOOD VESSEL CALCIFICATION; CHINA; COMPLICATION; CORONARY ARTERY DISEASE; CROSS-SECTIONAL STUDY; DIAGNOSTIC IMAGING; ECHOGRAPHY; FEMALE; HUMAN; LIVER; MALE; MIDDLE AGED; NONALCOHOLIC FATTY LIVER; PREVALENCE; X-RAY COMPUTED TOMOGRAPHY;

AGED; CHINA; CORONARY ARTERY DISEASE; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; LIVER; MALE; MIDDLE AGED; NON-ALCOHOLIC FATTY LIVER DISEASE; PREVALENCE; TOMOGRAPHY, X-RAY COMPUTED; ULTRASONOGRAPHY; VASCULAR CALCIFICATION;

EID: 85028585990     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-017-09851-5     Document Type: Article

References (55)

1. Mendis, S. et al. Global atlas on cardiovascular disease prevention and control. Geneva World Health Organization (2012).
2. Greenland, P. et al. ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 56, e50-103 (2010).
3. Raggi, P. et al. Coronary artery calcium to predict all-cause mortality in elderly men and women. J Am Coll Cardiol 52, 17-23 (2008).
4. Polonsky, T. S. et al. Coronary artery calcium score and risk classification for coronary heart disease prediction. JAMA 303, 1610-1616 (2010).
5. Budoff, M. J. et al. Long-term prognosis associated with coronary calcification: observations from a registry of 25,253 patients. J Am Coll Cardiol 49, 1860-1870 (2007).
6. Budoff, M. J. et al. Progression of coronary artery calcium predicts all-cause mortality. JACC Cardiovasc Imaging 3, 1229-1236 (2010).
7. Chalasani, N. et al. The diagnosis and management of non-alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association. Hepatology 55, 2005-2023 (2012).
8. Targher, G., Marra, F. & Marchesini, G. Increased risk of cardiovascular disease in non-alcoholic fatty liver disease: causal effect or epiphenomenon? Diabetologia 51, 1947-1953 (2008).
9. Ekstedt, M. et al. Long-term follow-up of patients with NAFLD and elevated liver enzymes. Hepatology 44, 865-873 (2006).
10. Lee, Y. H. et al. The severity of Fatty liver disease relating to metabolic abnormalities independently predicts coronary calcification. Radiol Res Pract 2011, 586785 (2011).
11. Targher, G. et al. Nonalcoholic fatty liver disease is independently associated with an increased incidence of cardiovascular events in type 2 diabetic patients. Diabetes Care 30, 2119-2121 (2007).
12. Chhabra, R. et al. Association of coronary artery calcification with hepatic steatosis in asymptomatic individuals. Mayo Clin Proc 88, 1259-1265 (2013).
13. Lee, M. K. et al. Higher association of coronary artery calcification with non-alcoholic fatty liver disease than with abdominal obesity in middle-aged Korean men: the Kangbuk Samsung Health Study. Cardiovasc Diabetol 14, 88 (2015).
14. Kim, L. K. et al. Impact of metabolic syndrome on the progression of coronary calcium and of coronary artery disease assessed by repeated cardiac computed tomography scans. Cardiovasc Diabetol 15, 92 (2016).
15. Kim, J. Y. et al. Relationship between non-alcoholic fatty liver disease, metabolic syndrome and insulin resistance in Korean adults: A cross-sectional study. Clin Chim Acta 458, 12-17 (2016).
16. Chen, C. H., Nien, C. K., Yang, C. C. & Yeh, Y. H. Association between nonalcoholic fatty liver disease and coronary artery calcification. Dig Dis Sci 55, 1752-1760 (2010).
17. Kim, D. et al. Nonalcoholic fatty liver disease is associated with coronary artery calcification. Hepatology 56, 605-613 (2012).
18. Ding, J. et al. Association between non-subcutaneous adiposity and calcified coronary plaque: a substudy of the Multi-Ethnic Study of Atherosclerosis. Am J Clin Nutr 88, 645-650 (2008).
19. VanWagner, L. B. et al. Associations between nonalcoholic fatty liver disease and subclinical atherosclerosis in middle-aged adults: the Coronary Artery Risk Development in Young Adults Study. Atherosclerosis 235, 599-605 (2014).
20. Kwak, M. S. et al. Nonalcoholic fatty liver disease is associated with coronary artery calcium score in diabetes patients with higher HbA1c. Diabetol Metab Syndr 7, 28 (2015).
21. McKimmie, R. L. et al. Hepatic steatosis and subclinical cardiovascular disease in a cohort enriched for type 2 diabetes: the Diabetes Heart Study. Am J Gastroenterol 103, 3029-3035 (2008).
22. Al Rifai, M. et al. The association of nonalcoholic fatty liver disease, obesity, and metabolic syndrome, with systemic inflammation and subclinical atherosclerosis: the Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis 239, 629-633 (2015).
23. Mellinger, J. L. et al. Hepatic steatosis and cardiovascular disease outcomes: An analysis of the Framingham Heart Study. J Hepatol 63, 470-476 (2015).
24. Sung, K. C. et al. Arterial stiffness, fatty liver and the presence of coronary artery calcium in a large population cohort. Cardiovasc Diabetol 12, 162 (2013).
25. Nambi, V. et al. Common carotid artery intima-media thickness is as good as carotid intima-media thickness of all carotid artery segments in improving prediction of coronary heart disease risk in the Atherosclerosis Risk in Communities (ARIC) study. Eur Heart J 33, 183-190 (2012).
26. Lorenz, M. W. et al. Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analysis. Circulation 115, 459-467 (2007).
27. Lankarani, K. B. et al. Common carotid intima-media thickness in patients with non-alcoholic fatty liver disease: a population-based case-control study. Korean J Gastroenterol 62, 344-351 (2013).
28. Park, H. E. et al. Nonalcoholic Fatty Liver Disease Is Associated With Coronary Artery Calcification Development: A Longitudinal Study. J Clin Endocrinol Metab 101, 3134-3143 (2016).
29. Sung, K. C. et al. Fatty Liver, Insulin Resistance, and Obesity: Relationships With Increase in Coronary Artery Calcium Over Time. Clin Cardiol 39, 321-328 (2016).
30. Li, Z. et al. Prevalence of nonalcoholic fatty liver disease in mainland of China: a meta-analysis of published studies. J Gastroenterol Hepatol 29, 42-51 (2014).
31. Clark, J. M. The epidemiology of nonalcoholic fatty liver disease in adults. J Clin Gastroenterol 40(Suppl 1), S5-10 (2006).
32. Lavoie, J. M. & Pighon, A. NAFLD, Estrogens, and Physical Exercise: The Animal Model. J Nutr Metab 2012, 914938 (2012).
33. Gutierrez-Grobe, Y. et al. Prevalence of non alcoholic fatty liver disease in premenopausal, posmenopausal and polycystic ovary syndrome women. The role of estrogens. Ann Hepatol 9, 402-409 (2010).
34. Kim, M. K. et al. Association between nonalcoholic fatty liver disease and coronary artery calcification in postmenopausal women. Menopause 22, 1323-1327 (2015).
35. Kim, H. J. et al. Gender-based differences in the relationship between fatty liver disease and atherosclerosis. Cardiovasc J Afr 27, 1-6 (2016).
36. Liu, H. & Lu, H. Y. Nonalcoholic fatty liver disease and cardiovascular disease. World J Gastroenterol 20, 8407-8415 (2014).
37. Yang, H. R. & Chang, E. J. Insulin resistance, body composition, and fat distribution in obese children with nonalcoholic fatty liver disease. Asia Pac J Clin Nutr 25, 126-133 (2016).
38. Erkan, G. et al. The relationship between insulin resistance, metabolic syndrome and nonalcoholic fatty liver disease in non-obese non-diabetic Turkish individuals: A pilot study. Turk J Gastroenterol 25(Suppl 1), 63-68 (2014).
39. Sung, K. C., Jeong, W. S., Wild, S. H. & Byrne, C. D. Combined influence of insulin resistance, overweight/obesity, and fatty liver as risk factors for type 2 diabetes. Diabetes Care 35, 717-722 (2012).
40. Korenblat, K. M., Fabbrini, E., Mohammed, B. S. & Klein, S. Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects. Gastroenterology 134, 1369-1375 (2008).
41. Koroglu, E. et al. Role of oxidative stress and insulin resistance in disease severity of non-alcoholic fatty liver disease. Turk J Gastroenterol 27, 361-366 (2016).
42. Blaha, M. J. et al. The relationship between insulin resistance and incidence and progression of coronary artery calcification: the Multi-Ethnic Study of Atherosclerosis (MESA). Diabetes Care 34, 749-751 (2011).
43. Spahis, S., Delvin, E., Borys, J. M. & Levy, E. Oxidative Stress as a Critical Factor in Nonalcoholic Fatty Liver Disease Pathogenesis. Antioxid Redox Signal (2016).
44. Bhatia, L. S., Curzen, N. P. & Byrne, C. D. Nonalcoholic fatty liver disease and vascular risk. Curr Opin Cardiol 27, 420-428 (2012).
45. Liu, J. et al. Fatty liver, abdominal adipose tissue and atherosclerotic calcification in African Americans: the Jackson Heart Study. Atherosclerosis 224, 521-525 (2012).
46. Saarikoski, L. A. et al. Low serum adiponectin levels in childhood and adolescence predict increased intima-media thickness in adulthood. The Cardiovascular Risk in Young Finns Study. Ann Med, 1-26 (2016).
47. Ntzouvani, A. et al. Reduced circulating adiponectin levels are associated with the metabolic syndrome independently of obesity, lipid indices and serum insulin levels: a cross-sectional study. Lipids Health Dis 15, 140 (2016).
48. Hernaez, R. et al. Diagnostic accuracy and reliability of ultrasonography for the detection of fatty liver: a meta-analysis. Hepatology 54, 1082-1090 (2011).
49. Kleiner, D. E. et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 41, 1313-1321 (2005).
50. Hao, Z. et al. The Association between Ideal Cardiovascular Health Metrics and Extracranial Carotid Artery Stenosis in a Northern Chinese Population: A Cross-Sectional Study. Sci Rep 6, 31720 (2016).
51. Fan, J. G. et al. Guidelines for the diagnosis and management of nonalcoholic fatty liver disease: update 2010: (published in Chinese on Chinese Journal of Hepatology 2010; 18:163-166). J Dig Dis 12, 38-44 (2011).
52. Farrell, G. C. et al. Guidelines for the assessment and management of non-alcoholic fatty liver disease in the Asia-Pacific region: executive summary. J Gastroenterol Hepatol 22, 775-777 (2007).
53. Agatston, A. S. et al. Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol 15, 827-832 (1990).
54. Luo, T. Y. et al. Ideal Cardiovascular Health Metrics and Coronary Artery Calcification in Northern Chinese Population: A Cross-sectional Study. Biomed Environ Sci 29, 475-483 (2016).
55. Pletcher, M. J., Tice, J. A., Pignone, M. & Browner, W. S. Using the coronary artery calcium score to predict coronary heart disease events: a systematic review and meta-analysis. Arch Intern Med 164, 1285-1292 (2004).