Genetic mutation analysis at early stages of cell line development using next generation sequencing

Biotechnology progress

Volumn 32, Issue 3, 2016, Pages 813-817

  Wright, Chapman ^a   Groot, Joost ^a   Swahn, Samantha ^a   McLaughlin, Helen ^a   Liu, Mei ^a   Xu, Chongfeng ^a   Sun, Chao ^a   Zheng, Eric ^a   Estes, Scott ^a  

^a BIOGEN   (United States)

Author keywords

amplicon sequencing; CHO; early stage cell line development; mutation detection

Indexed keywords

MASS SPECTROMETRY; PROTEINS; SOFTWARE TESTING; THROUGHPUT; TURNAROUND TIME;

AMERICAN INSTITUTE OF CHEMICAL ENGINEERS; AMPLICONS; CELL LINES; CHINESE HAMSTER OVARY; CONFIRMATION METHODS; DEVELOPMENT WORKFLOW; MUTATION DETECTION; NEXT-GENERATION SEQUENCING;

CELL CULTURE;

ANIMAL; BIOLOGY; CELL CULTURE; CHO CELL LINE; CRICETULUS; DNA SEQUENCE; HIGH THROUGHPUT SEQUENCING; MASS SPECTROMETRY; MUTATION;

ANIMALS; CELLS, CULTURED; CHO CELLS; COMPUTATIONAL BIOLOGY; CRICETULUS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; MASS SPECTROMETRY; MUTATION; SEQUENCE ANALYSIS, DNA;

EID: 85028257064     PISSN: None     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.2263     Document Type: Article

References (15)