-
2
-
-
34347266509
-
Changes in causes of death in systemic sclerosis, 1972-2002
-
Steen VD, Medsger TA. Changes in causes of death in systemic sclerosis, 1972-2002. Ann Rheum Dis 2007, 66:940-944.
-
(2007)
Ann Rheum Dis
, vol.66
, pp. 940-944
-
-
Steen, V.D.1
Medsger, T.A.2
-
3
-
-
0038799767
-
Interstitial lung disease in scleroderma
-
White B. Interstitial lung disease in scleroderma. Rheum Dis Clin North Am 2003, 29:371-390.
-
(2003)
Rheum Dis Clin North Am
, vol.29
, pp. 371-390
-
-
White, B.1
-
4
-
-
0036124419
-
Systemic sclerosis: demographic, clinical and serological features and survival in 1,012 Italian patients
-
Ferri C, Valentini G, Cozzi F, Sebastiani M, Michelassi C, La Montagna G, Bullo A, Cazzato M, Tirri E, Storino F, Giuggioli D, Cuomo G, Rosada M, Bombardieri S, Todesco S, Tirri G, . Systemic Sclerosis Study Group of the Italian Society of Rheumatology (SIR-GSSSc) Systemic sclerosis: demographic, clinical and serological features and survival in 1,012 Italian patients. Medicine (Baltimore) 2002, 81:139-153. Systemic Sclerosis Study Group of the Italian Society of Rheumatology (SIR-GSSSc).
-
(2002)
Medicine (Baltimore)
, vol.81
, pp. 139-153
-
-
Ferri, C.1
Valentini, G.2
Cozzi, F.3
Sebastiani, M.4
Michelassi, C.5
La Montagna, G.6
Bullo, A.7
Cazzato, M.8
Tirri, E.9
Storino, F.10
Giuggioli, D.11
Cuomo, G.12
Rosada, M.13
Bombardieri, S.14
Todesco, S.15
Tirri, G.16
-
5
-
-
33947697880
-
The natural course of progressive systemic sclerosis patients with interstitial lung involvement
-
Benan M, Hande I, Ongen G. The natural course of progressive systemic sclerosis patients with interstitial lung involvement. Clin Rheumatol 2007, 26:349-354.
-
(2007)
Clin Rheumatol
, vol.26
, pp. 349-354
-
-
Benan, M.1
Hande, I.2
Ongen, G.3
-
6
-
-
0025046335
-
Interstitial lung disease in progressive systemic sclerosis: high resolution CT versus radiography
-
Schurawitzki H, Stiglbauer R, Graninger W, Herold C, Po¨lzleitner D, Burghuber OC, Tscholakoff D. Interstitial lung disease in progressive systemic sclerosis: high resolution CT versus radiography. Radiology 1990, 176:755-759.
-
(1990)
Radiology
, vol.176
, pp. 755-759
-
-
Schurawitzki, H.1
Stiglbauer, R.2
Graninger, W.3
Herold, C.4
Po¨lzleitner, D.5
Burghuber, O.C.6
Tscholakoff, D.7
-
7
-
-
0036635291
-
Glivec (STI571, Imatinib), a rationally developed, targeted anticancer drug
-
Capdeville R, Buchdunger E, Zimmeermann J, Matter A. Glivec (STI571, Imatinib), a rationally developed, targeted anticancer drug. Nat Rev Drug Discov 2002, 1:493-502.
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 493-502
-
-
Capdeville, R.1
Buchdunger, E.2
Zimmeermann, J.3
Matter, A.4
-
8
-
-
15244339164
-
Imatinib mesylate inhibits the pro-fibrogenic activity of TGF-β and prevents bleomycin mediated lung fibrosis
-
Daniels CE, Wilkes MC, Edens M, Kottom TJ, Murphy SJ, Limper AH, Leof EB. Imatinib mesylate inhibits the pro-fibrogenic activity of TGF-β and prevents bleomycin mediated lung fibrosis. J Clin Invest 2004, 114:1308-1316.
-
(2004)
J Clin Invest
, vol.114
, pp. 1308-1316
-
-
Daniels, C.E.1
Wilkes, M.C.2
Edens, M.3
Kottom, T.J.4
Murphy, S.J.5
Limper, A.H.6
Leof, E.B.7
-
9
-
-
0031454003
-
CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins
-
Carrol M, Ohno-Jones S, Tamura S, Buchdunger E, Zimmermann J, Lydon NB, Gilliland DG, Druker BJ. CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins. Blood 1997, 90:4947-4952.
-
(1997)
Blood
, vol.90
, pp. 4947-4952
-
-
Carrol, M.1
Ohno-Jones, S.2
Tamura, S.3
Buchdunger, E.4
Zimmermann, J.5
Lydon, N.B.6
Gilliland, D.G.7
Druker, B.J.8
-
10
-
-
80155206225
-
Imatinib in active diffuse cutaneous systemic sclerosis: results of a six-month, randomized, double-blind, placebo-controlled, proof-of-concept pilot study at a single center
-
Pope J, McBain D, Petrlich L, Watson S, Vanderhoek L, de Leon F, Seney S, Summers K. Imatinib in active diffuse cutaneous systemic sclerosis: results of a six-month, randomized, double-blind, placebo-controlled, proof-of-concept pilot study at a single center. Arthritis Rheum 2011, 63:3547-3551.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 3547-3551
-
-
Pope, J.1
McBain, D.2
Petrlich, L.3
Watson, S.4
Vanderhoek, L.5
de Leon, F.6
Seney, S.7
Summers, K.8
-
11
-
-
79955860261
-
Imatinib mesylate (Gleevec) in the treatment of diffuse cutaneous systemic sclerosis: results of a 1-year, phase IIa, single-arm, open-label clinical trial
-
Spiera RF, Gordon JK, Mersten JN, Magro CM, Mehta M, Wildman HF, kloiber S, Kirou KA, Lyman S, Crow MK. Imatinib mesylate (Gleevec) in the treatment of diffuse cutaneous systemic sclerosis: results of a 1-year, phase IIa, single-arm, open-label clinical trial. Ann Rheum Dis 2011, 70:1003-1009.
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 1003-1009
-
-
Spiera, R.F.1
Gordon, J.K.2
Mersten, J.N.3
Magro, C.M.4
Mehta, M.5
Wildman, H.F.6
kloiber, S.7
Kirou, K.A.8
Lyman, S.9
Crow, M.K.10
-
12
-
-
80155204477
-
A one-year, phase I/IIa, open-label pilot trial of imatinib mesylate in the treatment of systemic sclerosis-associated active interstitial lung disease
-
Khanna D, Saggar R, Mayes MD, Abtin F, Clements PJ, Maranian P, Assassi S, Saggar R, Singh RR, Furst DE. A one-year, phase I/IIa, open-label pilot trial of imatinib mesylate in the treatment of systemic sclerosis-associated active interstitial lung disease. Arthritis Rheum 2011, 63:3540-3546.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 3540-3546
-
-
Khanna, D.1
Saggar, R.2
Mayes, M.D.3
Abtin, F.4
Clements, P.J.5
Maranian, P.6
Assassi, S.7
Saggar, R.8
Singh, R.R.9
Furst, D.E.10
-
13
-
-
84859248430
-
A multi-center, open-label, proof of concept study of imatinib mesylate demonstrate no benefit for the treatment of fibrosis in patients with early, diffuse systemic sclerosis. [abstract]
-
Distler O, Distler JHW, Varga J, Denton CP, Lafyatis RA, Wigley FM, Schett G. A multi-center, open-label, proof of concept study of imatinib mesylate demonstrate no benefit for the treatment of fibrosis in patients with early, diffuse systemic sclerosis. [abstract]. Arthritis Rheum 2010, 62:560.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 560
-
-
Distler, O.1
Distler, J.H.W.2
Varga, J.3
Denton, C.P.4
Lafyatis, R.A.5
Wigley, F.M.6
Schett, G.7
-
14
-
-
84867889852
-
Low-dose imatinib in the treatment of severe systemic sclerosis: a case series of six Chinese patients and literature review
-
Guo L, Chen XX, Gu YY, Zou HJ, Ye S. Low-dose imatinib in the treatment of severe systemic sclerosis: a case series of six Chinese patients and literature review. Clin Rheumatol 2012, 31:1395-1400.
-
(2012)
Clin Rheumatol
, vol.31
, pp. 1395-1400
-
-
Guo, L.1
Chen, X.X.2
Gu, Y.Y.3
Zou, H.J.4
Ye, S.5
-
15
-
-
84868214290
-
Imatinib mesylate in scleroderma-associated diffuse skin fibrosis: a phase II multicentre randomized double-blinded controlled trial
-
Prey S, Ezzedine K, Doussau A, Grandoulier AS, Barcat D, Chatelus E, Diot E, Durant C, Havchulla E, de Korwin-Krokowski JD, Kostrzewa E, Quemeneur T, Paul C, Schaeverbeke T, seneschal J, Solanilla A, Sparsa A, Bouchet S, Lepreux S, Mahon FX, Chene G, Tai¨eb A. Imatinib mesylate in scleroderma-associated diffuse skin fibrosis: a phase II multicentre randomized double-blinded controlled trial. Br J Dermatol 2012, 167:1138-1144.
-
(2012)
Br J Dermatol
, vol.167
, pp. 1138-1144
-
-
Prey, S.1
Ezzedine, K.2
Doussau, A.3
Grandoulier, A.S.4
Barcat, D.5
Chatelus, E.6
Diot, E.7
Durant, C.8
Havchulla, E.9
de Korwin-Krokowski, J.D.10
Kostrzewa, E.11
Quemeneur, T.12
Paul, C.13
Schaeverbeke, T.14
seneschal, J.15
Solanilla, A.16
Sparsa, A.17
Bouchet, S.18
Lepreux, S.19
Mahon, F.X.20
Chene, G.21
Tai¨eb, A.22
more..
-
17
-
-
0024536437
-
Optimal two stage designs for phase II clinical trials
-
Simon R. Optimal two stage designs for phase II clinical trials. Control Clin Trials 1989, 10:1-10.
-
(1989)
Control Clin Trials
, vol.10
, pp. 1-10
-
-
Simon, R.1
-
18
-
-
0018887574
-
Preliminary criteria for the classification of systemic sclerosis (scleroderma)
-
Subcommitte for Scleroderma Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Commitee Preliminary criteria for the classification of systemic sclerosis (scleroderma). Arthrtis Rheum 1980, 23:581-590. Subcommitte for Scleroderma Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Commitee.
-
(1980)
Arthrtis Rheum
, vol.23
, pp. 581-590
-
-
-
19
-
-
0021256105
-
The measurement of dyspnea: contents, inter-observer agreement, and physiologic correlates of two new clinical indexes
-
Mahler DA, Weinberg DHW, Wells CK, Feinstein AR. The measurement of dyspnea: contents, inter-observer agreement, and physiologic correlates of two new clinical indexes. Chest 1984, 85:751-758.
-
(1984)
Chest
, vol.85
, pp. 751-758
-
-
Mahler, D.A.1
Weinberg, D.H.W.2
Wells, C.K.3
Feinstein, A.R.4
-
20
-
-
21744434300
-
Standardisation of the measurement of lung volumes
-
Wanger J, Clausen JL, Coates A. Standardisation of the measurement of lung volumes. Eur Respir J 2005, 26:511-522.
-
(2005)
Eur Respir J
, vol.26
, pp. 511-522
-
-
Wanger, J.1
Clausen, J.L.2
Coates, A.3
-
21
-
-
21744439879
-
Standardisation of the single-breath determination of carbon monoxide uptake in the lung
-
Macintyre N, Crapo RO, Viegi G, Johnson DC, van der Grinten CP, Brusasco V, Burgos F, Casaburi R, Coates A, Enright P, Gustafsson P, Hankinson J, Jensen R, McKay R, Miller MR, Navajas D, Pedersen OF, Pellegrino R, Wanger J. Standardisation of the single-breath determination of carbon monoxide uptake in the lung. Eur Respir J 2005, 26:720-735.
-
(2005)
Eur Respir J
, vol.26
, pp. 720-735
-
-
Macintyre, N.1
Crapo, R.O.2
Viegi, G.3
Johnson, D.C.4
van der Grinten, C.P.5
Brusasco, V.6
Burgos, F.7
Casaburi, R.8
Coates, A.9
Enright, P.10
Gustafsson, P.11
Hankinson, J.12
Jensen, R.13
McKay, R.14
Miller, M.R.15
Navajas, D.16
Pedersen, O.F.17
Pellegrino, R.18
Wanger, J.19
-
22
-
-
33748580286
-
High resolution computer tomography in fibrosing alveolitis associated with systemic sclerosis
-
Launay D, Remy-Jardin M, Micron-Pasturel U. High resolution computer tomography in fibrosing alveolitis associated with systemic sclerosis. J Rheum 2006, 33:1789-1801.
-
(2006)
J Rheum
, vol.33
, pp. 1789-1801
-
-
Launay, D.1
Remy-Jardin, M.2
Micron-Pasturel, U.3
-
23
-
-
0029048089
-
Inter and intraobserver variability of total skin thickness score (modified Rodnan TSS) in systemic sclerosis
-
Clements P, Lachenbruch P, Siebold J, White B, Weiner S, Martin R, Weinstein A, Weisman M, Mayes M, Collier D, Wigley F, Medsger JT, Steen V, Moreland L, Dixon M, Massa M, Lally E, McCloskey D, Varga J, et al. Inter and intraobserver variability of total skin thickness score (modified Rodnan TSS) in systemic sclerosis. J Rheumatol 1995, 22:1281-1285.
-
(1995)
J Rheumatol
, vol.22
, pp. 1281-1285
-
-
Clements, P.1
Lachenbruch, P.2
Siebold, J.3
White, B.4
Weiner, S.5
Martin, R.6
Weinstein, A.7
Weisman, M.8
Mayes, M.9
Collier, D.10
Wigley, F.11
Medsger, J.T.12
Steen, V.13
Moreland, L.14
Dixon, M.15
Massa, M.16
Lally, E.17
McCloskey, D.18
Varga, J.19
-
24
-
-
13444252280
-
Correlation of the degree of dyspnea with health-related quality of life, functional abilities, and diffusing capacity of carbon monoxide in patients with systemic sclerosis and active alveolitis
-
Khanna D, Clements PJ, Furst DE, Chon Y, Elashoff R, Roth MD, Sterz MG, Chung J, Fitzgerald JD, Seibold JR, Varga J, Theodore A, Wigley FM, Silver RM, Steen VD, Mayes MD, Connolly MK, Fessler BJ, Rothfiels NF, Mubarak K, Molitor J, Tashkin DP, . Scleroderma Lung Study Group Correlation of the degree of dyspnea with health-related quality of life, functional abilities, and diffusing capacity of carbon monoxide in patients with systemic sclerosis and active alveolitis. Arthritis Rheum 2005, 52:592-600. Scleroderma Lung Study Group.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 592-600
-
-
Khanna, D.1
Clements, P.J.2
Furst, D.E.3
Chon, Y.4
Elashoff, R.5
Roth, M.D.6
Sterz, M.G.7
Chung, J.8
Fitzgerald, J.D.9
Seibold, J.R.10
Varga, J.11
Theodore, A.12
Wigley, F.M.13
Silver, R.M.14
Steen, V.D.15
Mayes, M.D.16
Connolly, M.K.17
Fessler, B.J.18
Rothfiels, N.F.19
Mubarak, K.20
Molitor, J.21
Tashkin, D.P.22
more..
-
25
-
-
85047496188
-
-
Guidance for Industry. E6 Good Clinical Practice: Consolidated Guidance. [http://www.fda.gov/downloads/Drugs/Guidances/ucm073122.pdf].
-
-
-
-
26
-
-
33745227399
-
Cyclophosphamide versus placebo in scleroderma lung disease
-
Tashkin DP, Elashoff R, Clements PJ, Goldin J, Roth MD, Furst DE, Arriola E, Silver R, Strange C, Bolster M, Seibold JR, Riley DJ, Hsu VM, Varga J, Schraufnagel DE, Theodore A, Simms R, Wise R, Wigley F, White B, Steen V, Read C, Mayes M, Parsley E, Mubarak K, Connolly MK, Golden J, Olman M, Fessler B, Rothfield N, Metersky M, . Scleroderma Lung Study Research Group Cyclophosphamide versus placebo in scleroderma lung disease. N Engl J Med 2006, 354:2655-2666. Scleroderma Lung Study Research Group.
-
(2006)
N Engl J Med
, vol.354
, pp. 2655-2666
-
-
Tashkin, D.P.1
Elashoff, R.2
Clements, P.J.3
Goldin, J.4
Roth, M.D.5
Furst, D.E.6
Arriola, E.7
Silver, R.8
Strange, C.9
Bolster, M.10
Seibold, J.R.11
Riley, D.J.12
Hsu, V.M.13
Varga, J.14
Schraufnagel, D.E.15
Theodore, A.16
Simms, R.17
Wise, R.18
Wigley, F.19
White, B.20
Steen, V.21
Read, C.22
Mayes, M.23
Parsley, E.24
Mubarak, K.25
Connolly, M.K.26
Golden, J.27
Olman, M.28
Fessler, B.29
Rothfield, N.30
Metersky, M.31
more..
-
27
-
-
84887463104
-
Levels of target activation predict antifibrotic responses to tyrosine kinase inhibitors
-
Maurer B, Distler A, Dees C, Khan K, Denton CP, Abraham D, Gay RE, Michel BA, Gay S, Distler J, Distler O. Levels of target activation predict antifibrotic responses to tyrosine kinase inhibitors. Ann Rheum Dis 2013, 72:2039-2046.
-
(2013)
Ann Rheum Dis
, vol.72
, pp. 2039-2046
-
-
Maurer, B.1
Distler, A.2
Dees, C.3
Khan, K.4
Denton, C.P.5
Abraham, D.6
Gay, R.E.7
Michel, B.A.8
Gay, S.9
Distler, J.10
Distler, O.11
-
28
-
-
0031454003
-
CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins
-
Carroll M, Ohno-Jones S, Tamura S, Buchdunger E, Zimmermann J, Lydon NB, Gilliand DG, Druker BJ. CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins. Blood 1997, 15:4947-4952.
-
(1997)
Blood
, vol.15
, pp. 4947-4952
-
-
Carroll, M.1
Ohno-Jones, S.2
Tamura, S.3
Buchdunger, E.4
Zimmermann, J.5
Lydon, N.B.6
Gilliand, D.G.7
Druker, B.J.8
-
29
-
-
17044403497
-
Macrophage colony-stimulating factor receptor c-fms is a novel target of imatinib
-
Dewar AL, Cambareri AC, Zannettino AC, Miller BL, Doherty KV, Hughes TP, Lyons AB. Macrophage colony-stimulating factor receptor c-fms is a novel target of imatinib. Blood 2005, 105:3127-3132.
-
(2005)
Blood
, vol.105
, pp. 3127-3132
-
-
Dewar, A.L.1
Cambareri, A.C.2
Zannettino, A.C.3
Miller, B.L.4
Doherty, K.V.5
Hughes, T.P.6
Lyons, A.B.7
-
30
-
-
15244351682
-
Imatinib inhibits T-cell receptor-mediated T-cell proliferation and activation in a dose-dependent manner
-
Lore´ K, Greiner E, Magnusson MK, Price DA, Douek DC, Dumbar CE. Imatinib inhibits T-cell receptor-mediated T-cell proliferation and activation in a dose-dependent manner. Blood 2005, 105:2473-2479.
-
(2005)
Blood
, vol.105
, pp. 2473-2479
-
-
Lore´, K.1
Greiner, E.2
Magnusson, M.K.3
Price, D.A.4
Douek, D.C.5
Dumbar, C.E.6
-
31
-
-
84877094679
-
Imatinib: novel treatment of immune-mediated kidney injury
-
Wallace E, Gewin L. Imatinib: novel treatment of immune-mediated kidney injury. J Am Soc Nephrol 2013, 24:694-701.
-
(2013)
J Am Soc Nephrol
, vol.24
, pp. 694-701
-
-
Wallace, E.1
Gewin, L.2
-
32
-
-
84857048686
-
Tyrosine kinase inhibitors ameliorate autoimmune encephalomyelitis in a mouse model of multiple sclerosis
-
Crespo O, Kang SC, Daneman R, Lindstrom TM, Ho PP, Sobel RA, Steinman L, Robinson WH. Tyrosine kinase inhibitors ameliorate autoimmune encephalomyelitis in a mouse model of multiple sclerosis. J Clin Immunol 2011, 31:1010-1020.
-
(2011)
J Clin Immunol
, vol.31
, pp. 1010-1020
-
-
Crespo, O.1
Kang, S.C.2
Daneman, R.3
Lindstrom, T.M.4
Ho, P.P.5
Sobel, R.A.6
Steinman, L.7
Robinson, W.H.8
-
33
-
-
33749446861
-
Selective tyrosine kinase inhibition by imatinib mesylate for the treatment of autoimmune arthritis
-
Paniagua RT, Sharpe O, Ho PP, Chan SM, Chang A, Higgins JP, Tomooka BH, Thomas FM, Song JJ, Goodman SB, Lee DM, Genovese MC, Utz PJ, Steinman L, Robinson WH. Selective tyrosine kinase inhibition by imatinib mesylate for the treatment of autoimmune arthritis. J Clin Invest 2006, 116:2633-2642.
-
(2006)
J Clin Invest
, vol.116
, pp. 2633-2642
-
-
Paniagua, R.T.1
Sharpe, O.2
Ho, P.P.3
Chan, S.M.4
Chang, A.5
Higgins, J.P.6
Tomooka, B.H.7
Thomas, F.M.8
Song, J.J.9
Goodman, S.B.10
Lee, D.M.11
Genovese, M.C.12
Utz, P.J.13
Steinman, L.14
Robinson, W.H.15
-
34
-
-
57749094961
-
Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic mice
-
Louvet C, Szot GL, Lang J, Lee MR, Martinier N, Bollag G, Zhu S, Weiss A, Bluestone JA. Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic mice. Proc Natl Acad Sci U S A 2008, 105:18895-18900.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 18895-18900
-
-
Louvet, C.1
Szot, G.L.2
Lang, J.3
Lee, M.R.4
Martinier, N.5
Bollag, G.6
Zhu, S.7
Weiss, A.8
Bluestone, J.A.9
|