Cyclooxygenase inhibition abrogates aeroallergen-induced immune tolerance by suppressing prostaglandin I2 receptor signaling

The Journal of allergy and clinical immunology

Volumn 134, Issue 3, 2014, Pages 698-705.e5

  Zhou, Weisong ^a   Goleniewska, Kasia ^a   Zhang, Jian ^a   Dulek, Daniel E ^a   Toki, Shinji ^a   Lotz, Matthew T ^a   Newcomb, Dawn C ^a   Boswell, Madison G ^a   Polosukhin, Vasiliy V ^a   Milne, Ginger L ^a   Wu, Pingsheng ^a   Moore, Martin L ^b   FitzGerald, Garret A ^c   Peebles, R Stokes ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

allergy; immune tolerance; PGI(2)

Indexed keywords

ALLERGEN; ENZYME INHIBITOR; INDOMETACIN; OVALBUMIN; PROSTACYCLIN; PROSTACYCLIN RECEPTOR; PROSTAGLANDIN SYNTHASE;

129 MOUSE; ADVERSE EFFECTS; AIR POLLUTION; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; GENETICS; HUMAN; HYPERSENSITIVITY; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MOUSE; SIGNAL TRANSDUCTION;

AIR POLLUTION; ALLERGENS; ANIMALS; ENZYME INHIBITORS; EPOPROSTENOL; HUMANS; HYPERSENSITIVITY; IMMUNE TOLERANCE; INDOMETHACIN; MICE; MICE, 129 STRAIN; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; OVALBUMIN; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RECEPTORS, EPOPROSTENOL; SIGNAL TRANSDUCTION;

EID: 85027955906     PISSN: None     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2014.06.004     Document Type: Article

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