메뉴 건너뛰기




Volumn 31, Issue 5, 2011, Pages 1016-1023

Endothelial Grb2-associated binder 1 is crucial for postnatal angiogenesis

Author keywords

angiogenesis; endothelium; Gab1; growth factors; ischemia

Indexed keywords

ADAPTOR PROTEIN; CRE RECOMBINASE; GRB2 ASSOCIATED BINDER 1; MATRIGEL; MITOGEN ACTIVATED PROTEIN KINASE 1; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR; PROTEIN KINASE B; SCATTER FACTOR; TYROSINE; UNCLASSIFIED DRUG;

EID: 85027954042     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.111.224493     Document Type: Article
Times cited : (31)

References (40)
  • 2
    • 0026639806 scopus 로고
    • Angiogenesis
    • Folkman J, Shing Y. Angiogenesis. J Biol Chem. 1992;267:10931-10934.
    • (1992) J Biol Chem , vol.267 , pp. 10931-10934
    • Folkman, J.1    Shing, Y.2
  • 4
    • 0037453059 scopus 로고    scopus 로고
    • Angiogenic property of hepatocyte growth factor is dependent on upregulation of essential transcription factor for angiogenesis, ets-1
    • DOI 10.1161/01.CIR.0000055331.41937.AA
    • Tomita N, Morishita R, Taniyama Y, Koike H, Aoki M, Shimizu H, Matsumoto K, Nakamura T, Kaneda Y, Ogihara T. Angiogenic property of hepatocyte growth factor is dependent on upregulation of essential transcription factor for angiogenesis, ets-1. Circulation. 2003;107:1411-1417. (Pubitemid 36350741)
    • (2003) Circulation , vol.107 , Issue.10 , pp. 1411-1417
    • Tomita, N.1    Morishita, R.2    Taniyama, Y.3    Koike, H.4    Aoki, M.5    Shimizu, H.6    Matsumoto, K.7    Nakamura, T.8    Kaneda, Y.9    Ogihara, T.10
  • 6
    • 0032477844 scopus 로고    scopus 로고
    • Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor: The case for paracrine amplification of angiogenesis
    • Van Belle E, Witzenbichler B, Chen D, Silver M, Chang L, Schwall R, Isner JM. Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor: the case for paracrine amplification of angiogenesis. Circulation. 1998;97:381-390. (Pubitemid 28074339)
    • (1998) Circulation , vol.97 , Issue.4 , pp. 381-390
    • Van Belle, E.1    Witzenbichler, B.2    Chen, D.3    Silver, M.4    Chang, L.5    Schwall, R.6    Isner, J.M.7
  • 7
    • 0036006814 scopus 로고    scopus 로고
    • Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition
    • DOI 10.1016/S1359-6101(01)00029-6, PII S1359610101000296
    • Maulik G, Shrikhande A, Kijima T, Ma PC, Morrison PT, Salgia R. Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition. Cytokine Growth Factor Rev. 2002; 13:41-59. (Pubitemid 34436961)
    • (2002) Cytokine and Growth Factor Reviews , vol.13 , Issue.1 , pp. 41-59
    • Maulik, G.1    Shrikhande, A.2    Kijima, T.3    Ma, P.C.4    Morrison, P.T.5    Salgia, R.6
  • 8
    • 44449151030 scopus 로고    scopus 로고
    • Drug development of MET inhibitors: Targeting oncogene addiction and expedience
    • DOI 10.1038/nrd2530, PII NRD2530
    • Comoglio PM, Giordano S, Trusolino L. Drug development of MET inhibitors: targeting oncogene addiction and expedience. Nat Rev Drug Discov. 2008;7:504-516. (Pubitemid 351767118)
    • (2008) Nature Reviews Drug Discovery , vol.7 , Issue.6 , pp. 504-516
    • Comoglio, P.M.1    Giordano, S.2    Trusolino, L.3
  • 9
    • 0034547912 scopus 로고    scopus 로고
    • HGF/NK4, a four-kringle antagonist of hepatocyte growth factor, is an angiogenesis inhibitor that suppresses tumor growth and metastasis in mice
    • Kuba K, Matsumoto K, Date K, Shimura H, Tanaka M, Nakamura T. HGF/NK4, a four-kringle antagonist of hepatocyte growth factor, is an angiogenesis inhibitor that suppresses tumor growth and metastasis in mice. Cancer Res. 2000;60:6737-6743.
    • (2000) Cancer Res , vol.60 , pp. 6737-6743
    • Kuba, K.1    Matsumoto, K.2    Date, K.3    Shimura, H.4    Tanaka, M.5    Nakamura, T.6
  • 11
    • 0029855280 scopus 로고    scopus 로고
    • Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis
    • DOI 10.1038/384173a0
    • Weidner KM, Di Cesare S, Sachs M, Brinkmann V, Behrens J, Birchmeier W. Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis. Nature. 1996;384:173-176. (Pubitemid 26386473)
    • (1996) Nature , vol.384 , Issue.6605 , pp. 173-176
    • Weidner, K.M.1    Di Cesare, S.2    Sachs, M.3    Brinkmann, V.4    Behrens, J.5    Birchmeier, W.6
  • 12
    • 0034613198 scopus 로고    scopus 로고
    • Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases
    • Lock LS, Royal I, Naujokas MA, Park M. Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases. J Biol Chem. 2000;275:31536-31545.
    • (2000) J Biol Chem , vol.275 , pp. 31536-31545
    • Lock, L.S.1    Royal, I.2    Naujokas, M.A.3    Park, M.4
  • 13
    • 0033959896 scopus 로고    scopus 로고
    • A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling
    • DOI 10.1128/MCB.20.4.1448-1459.2000
    • Rodrigues GA, Falasca M, Zhang Z, Ong SH, Schlessinger J. A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling. Mol Cell Biol. 2000;20:1448-1459. (Pubitemid 30069264)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.4 , pp. 1448-1459
    • Rodrigues, G.A.1    Falasca, M.2    Zhang, Z.3    Ong, S.H.4    Schlessinger, J.5
  • 14
    • 0033020148 scopus 로고    scopus 로고
    • The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the Met receptor tyrosine kinase
    • Maroun CR, Holgado-Madruga M, Royal I, Naujokas MA, Fournier TM, Wong AJ, Park M. The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase. Mol Cell Biol. 1999;19:1784-1799. (Pubitemid 29098237)
    • (1999) Molecular and Cellular Biology , vol.19 , Issue.3 , pp. 1784-1799
    • Maroun, C.R.1    Holgado-Madruga, M.2    Royal, I.3    Naujokas, M.A.4    Fournier, T.M.5    Wong, A.J.6    Park, M.7
  • 15
    • 0032530384 scopus 로고    scopus 로고
    • Identification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast
    • DOI 10.1093/emboj/17.18.5374
    • Isakoff SJ, Cardozo T, Andreev J, Li Z, Ferguson KM, Abagyan R, Lemmon MA, Aronheim A, Skolnik EY. Identification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast. EMBO J. 1998;17:5374-5387. (Pubitemid 28427051)
    • (1998) EMBO Journal , vol.17 , Issue.18 , pp. 5374-5387
    • Isakoff, S.J.1    Cardozo, T.2    Andreev, J.3    Li, Z.4    Ferguson, K.M.5    Abagyan, R.6    Lemmon, M.A.7    Aronheim, A.8    Skolnik, E.Y.9
  • 16
    • 0035968279 scopus 로고    scopus 로고
    • Phosphotyrosines 627 and 659 of Gab1 constitute a bisphosphoryl tyrosine-based activation motif (BTAM) conferring binding and activation of SHP2
    • Cunnick JM, Mei L, Doupnik CA, Wu J. Phosphotyrosines 627 and 659 of Gab1 constitute a bisphosphoryl tyrosine-based activation motif (BTAM) conferring binding and activation of SHP2. J Biol Chem. 2001; 276:24380-24387.
    • (2001) J Biol Chem , vol.276 , pp. 24380-24387
    • Cunnick, J.M.1    Mei, L.2    Doupnik, C.A.3    Wu, J.4
  • 17
    • 0034607968 scopus 로고    scopus 로고
    • Requirement of SHP2 binding to Grb2-associated binder-1 for mitogen- activated protein kinase activation in response to lysophosphatidic acid and epidermal growth factor
    • DOI 10.1074/jbc.275.18.13842
    • Cunnick JM, Dorsey JF, Munoz-Antonia T, Mei L, Wu J. Requirement of SHP2 binding to Grb2-associated binder-1 for mitogen-activated protein kinase activation in response to lysophosphatidic acid and epidermal growth factor. J Biol Chem. 2000;275:13842-13848. (Pubitemid 30257458)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.18 , pp. 13842-13848
    • Cunnick, J.M.1    Dorsey, J.F.2    Munoz-Antonia, T.3    Mei, L.4    Wu, J.5
  • 19
    • 0034095213 scopus 로고    scopus 로고
    • Enhanced transformation by a plasma membrane-associated met oncoprotein: Activation of a phosphoinositide 3'-kinase-dependent autocrine loop involving hyaluronic acid and CD44
    • DOI 10.1128/MCB.20.10.3482-3496.2000
    • Kamikura DM, Khoury H, Maroun C, Naujokas MA, Park M. Enhanced transformation by a plasma membrane-associated met oncoprotein: activation of a phosphoinositide 3-kinase-dependent autocrine loop involving hyaluronic acid and CD44. Mol Cell Biol. 2000;20:3482-3496. (Pubitemid 30243894)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.10 , pp. 3482-3496
    • Kamikura, D.M.1    Khoury, H.2    Maroun, C.3    Naujokas, M.A.4    Park, M.5
  • 20
    • 0032730852 scopus 로고    scopus 로고
    • An epidermal growth factor receptor/Gab1 signaling pathway is required for activation of phosphoinositide 3-kinase by lysophosphatidic acid
    • Laffargue M, Raynal P, Yart A, Peres C, Wetzker R, Roche S, Payrastre B, Chap H. An epidermal growth factor receptor/Gab1 signaling pathway is required for activation of phosphoinositide 3-kinase by lysophosphatidic acid. J Biol Chem. 1999;274:32835-32841. (Pubitemid 129535317)
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.46 , pp. 32835-32841
    • Laffargue, M.1    Raynal, P.2    Yart, A.3    Peres, C.4    Wetzker, R.5    Roche, S.6    Payrastre, B.7    Chap, H.8
  • 22
    • 0035937767 scopus 로고    scopus 로고
    • A critical role for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of ras and mitogen-activated protein kinases by epidermal growth factor
    • Yart A, Laffargue M, Mayeux P, Chretien S, Peres C, Tonks N, Roche S, Payrastre B, Chap H, Raynal P. A critical role for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of ras and mitogen-activated protein kinases by epidermal growth factor. J Biol Chem. 2001;276:8856-8864.
    • (2001) J Biol Chem , vol.276 , pp. 8856-8864
    • Yart, A.1    Laffargue, M.2    Mayeux, P.3    Chretien, S.4    Peres, C.5    Tonks, N.6    Roche, S.7    Payrastre, B.8    Chap, H.9    Raynal, P.10
  • 25
    • 0033624921 scopus 로고    scopus 로고
    • Role of Gab l in heart, placenta, and skin development and growth factor- and cytokine-induced extracellular signal-regulated kinase mitogen- activated protein kinase activation
    • DOI 10.1128/MCB.20.10.3695-3704.2000
    • Itoh M, Yoshida Y, Nishida K, Narimatsu M, Hibi M, Hirano T. Role of Gab1 in heart, placenta, and skin development and growth factor- and cytokine-induced extracellular signal-regulated kinase mitogen-activated protein kinase activation. Mol Cell Biol. 2000;20:3695-3704. (Pubitemid 30243915)
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.10 , pp. 3695-3704
    • Itoh, M.1    Yoshida, Y.2    Nishida, K.3    Narimatsu, M.4    Hibi, M.5    Hirano, T.6
  • 26
    • 18844411108 scopus 로고    scopus 로고
    • Deletion of Gab1 in the liver leads to enhanced glucose tolerance and improved hepatic insulin action
    • DOI 10.1038/nm1227
    • Bard-Chapeau EA, Hevener AL, Long S, Zhang EE, Olefsky JM, Feng GS. Deletion of Gab1 in the liver leads to enhanced glucose tolerance and improved hepatic insulin action. Nat Med. 2005;11:567-571. (Pubitemid 40685981)
    • (2005) Nature Medicine , vol.11 , Issue.5 , pp. 567-571
    • Bard-Chapeau, E.A.1    Hevener, A.L.2    Long, S.3    Zhang, E.E.4    Olefsky, J.M.5    Feng, G.-S.6
  • 28
    • 62749184858 scopus 로고    scopus 로고
    • Non-redundant roles of the Gab1 and Gab2 scaffolding adapters in VEGF-mediated signalling, migration, and survival of endothelial cells
    • Caron C, Spring K, Laramee M, Chabot C, Cloutier M, Gu H, Royal I. Non-redundant roles of the Gab1 and Gab2 scaffolding adapters in VEGF-mediated signalling, migration, and survival of endothelial cells. Cell Signal. 2009;21:943-953.
    • (2009) Cell Signal , vol.21 , pp. 943-953
    • Caron, C.1    Spring, K.2    Laramee, M.3    Chabot, C.4    Cloutier, M.5    Gu, H.6    Royal, I.7
  • 31
    • 0037699955 scopus 로고    scopus 로고
    • Angiogenesis in health and disease
    • DOI 10.1038/nm0603-653
    • Carmeliet P. Angiogenesis in health and disease. Nat Med. 2003;9: 653-660. (Pubitemid 36749213)
    • (2003) Nature Medicine , vol.9 , Issue.6 , pp. 653-660
    • Carmeliet, P.1
  • 32
    • 0037326702 scopus 로고    scopus 로고
    • Signal transduction by vascular endothelial growth factor receptors
    • Claesson-Welsh L. Signal transduction by vascular endothelial growth factor receptors. Biochem Soc Trans. 2003;31:20-24. (Pubitemid 36241390)
    • (2003) Biochemical Society Transactions , vol.31 , Issue.1 , pp. 20-24
    • Claesson-Welsh, L.1
  • 33
    • 0038649977 scopus 로고    scopus 로고
    • Targeting of mitogen-activated protein kinases and phosphatidylinositol 3 kinase inhibits hepatocyte growth factor/scatter factor - Induced angiogenesis
    • DOI 10.1161/01.CIR.0000077501.19266.E5
    • Sengupta S, Sellers LA, Li RC, Gherardi E, Zhao G, Watson N, Sasisekharan R, Fan TP. Targeting of mitogen-activated protein kinases and phosphatidylinositol 3 kinase inhibits hepatocyte growth factor/ scatter factor-induced angiogenesis. Circulation. 2003;107:2955-2961. (Pubitemid 36736639)
    • (2003) Circulation , vol.107 , Issue.23 , pp. 2955-2961
    • Sengupta, S.1    Sellers, L.A.2    Li, R.-C.3    Gherardi, E.4    Zhao, G.5    Watson, N.6    Sasisekharan, R.7    Fan, T.-P.D.8
  • 34
    • 0042827955 scopus 로고    scopus 로고
    • 2+- and phosphoinositide 3-kinase/Akt-dependent phosphorylation in aortic endothelial cells
    • DOI 10.1042/BJ20030326
    • Makondo K, Kimura K, Kitamura N, Kitamura T, Yamaji D, Jung BD, Saito M. Hepatocyte growth factor activates endothelial nitric oxide synthase by Ca(2)- and phosphoinositide 3-kinase/Akt-dependent phosphorylation in aortic endothelial cells. Biochem J. 2003;374:63-69. (Pubitemid 37046929)
    • (2003) Biochemical Journal , vol.374 , Issue.1 , pp. 63-69
    • Makondo, K.1    Kimura, K.2    Kitamura, N.3    Kitamura, T.4    Yamaji, D.5    Dong Jung, B.6    Saito, M.7
  • 35
    • 0347660479 scopus 로고    scopus 로고
    • The role of Gab family scaffolding adapter proteins in the signal transduction of cytokine and growth factor receptors
    • DOI 10.1111/j.1349-7006.2003.tb01396.x
    • Nishida K, Hirano T. The role of Gab family scaffolding adapter proteins in the signal transduction of cytokine and growth factor receptors. Cancer Sci. 2003;94:1029-1033. (Pubitemid 38035515)
    • (2003) Cancer Science , vol.94 , Issue.12 , pp. 1029-1033
    • Nishida, K.1    Hirano, T.2
  • 36
    • 0037333264 scopus 로고    scopus 로고
    • The "gab" in signal transduction
    • Gu H, Neel BG. The "Gab" in signal transduction. Trends Cell Biol. 2003;13:122-130.
    • (2003) Trends Cell Biol , vol.13 , pp. 122-130
    • Gu, H.1    Neel, B.G.2
  • 37
    • 34247221517 scopus 로고    scopus 로고
    • The scaffolding adapter Gab1 mediates vascular endothelial growth factor signaling and is required for endothelial cell migration and capillary formation
    • DOI 10.1074/jbc.M611327200
    • Laramee M, Chabot C, Cloutier M, Stenne R, Holgado-Madruga M, Wong AJ, Royal I. The scaffolding adapter Gab1 mediates vascular endothelial growth factor and is required for endothelial cell migration and capillary formation. J Biol Chem. 2007;282:7758-7769. (Pubitemid 47093597)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.11 , pp. 7758-7769
    • Larame, M.1    Chabot, C.2    Cloutier, M.3    Stenne, R.4    Holgado-Madruga, M.5    Wong, A.J.6    Royal, I.7
  • 38
    • 0033910377 scopus 로고    scopus 로고
    • Enhanced secretion of cardiac hepatocyte growth factor from an infarct region is associated with less severe ventricular enlargement and improved cardiac function
    • DOI 10.1016/S0735-1097(00)00675-6, PII S0735109700006756
    • Yasuda S, Goto Y, Baba T, Satoh T, Sumida H, Miyazaki S, Nonogi H. Enhanced secretion of cardiac hepatocyte growth factor from an infarct region is associated with less severe ventricular enlargement and improved cardiac function. J Am Coll Cardiol. 2000;36:115-121. (Pubitemid 30466121)
    • (2000) Journal of the American College of Cardiology , vol.36 , Issue.1 , pp. 115-121
    • Yasuda, S.1    Goto, Y.2    Baba, T.3    Satoh, T.4    Sumida, H.5    Miyazaki, S.6    Nonogi, H.7
  • 40
    • 20944452151 scopus 로고    scopus 로고
    • Hepatocyte growth factor ameliorates the progression of experimental autoimmune myocarditis: A potential role for induction of T helper 2 cytokines
    • DOI 10.1161/01.RES.0000163016.52653.2e
    • Futamatsu H, Suzuki J, Mizuno S, Koga N, Adachi S, Kosuge H, Maejima Y, Hirao K, Nakamura T, Isobe M. Hepatocyte growth factor ameliorates the progression of experimental autoimmune myocarditis: a potential role for induction of T helper 2 cytokines. Circ Res. 2005;96:823-830. (Pubitemid 40604965)
    • (2005) Circulation Research , vol.96 , Issue.8 , pp. 823-830
    • Futamatsu, H.1    Suzuki, J.-I.2    Mizuno, S.3    Koga, N.4    Adachi, S.5    Kosuge, H.6    Maejima, Y.7    Hirao, K.8    Nakamura, T.9    Isobe, M.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.