Development of volume-stable adipose tissue constructs using polycaprolactone-based polyurethane scaffolds and fibrin hydrogels

Journal of Tissue Engineering and Regenerative Medicine

Volumn 10, Issue 10, 2016, Pages E409-E418

  Wittmann, Katharina ^a   Storck, Katharina ^b   Muhr, Christian ^a   Mayer, Helena ^b   Regn, Sybille ^b   Staudenmaier, Rainer ^b   Wiese, Hinrich ^c   Maier, Gerhard ^c   Bauer Kreisel, Petra ^a   Blunk, Torsten ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c POLYMATERIALS AG   (Germany)

Author keywords

adipogenesis; adipose tissue; adipose derived stem cells; fibrin; polyurethane; support structure; tissue engineering

Indexed keywords

CELL ENGINEERING; COPYRIGHTS; GELS; GROUND SUPPORTS; HYDROGELS; POLYURETHANES; SCAFFOLDS (BIOLOGY); TISSUE;

ADIPOGENESIS; ADIPOSE DERIVED STEM CELLS; ADIPOSE TISSUE; CELL-BE; CELL/B.E; CELL/BE; FIBRIN; POLYURETHANE SCAFFOLDS; SUPPORT STRUCTURES; TISSUES ENGINEERINGS;

STEM CELLS;

CCAAT ENHANCER BINDING PROTEIN ALPHA; DNA; FIBRIN; FIBRIN GLUE; GLUCOSE TRANSPORTER 4; LEPTIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; POLYCAPROLACTONE; POLYURETHAN; TRANSCRIPTION FACTOR AP 2;

ADIPOGENESIS; ADIPOSE DERIVED STEM CELL; ADIPOSE TISSUE; ADULT; ANIMAL EXPERIMENT; AP2 GENE; ARTERIOVENOUS SHUNT; ARTICLE; CEBPA GENE; CELL DIFFERENTIATION; CELL VIABILITY; COMPOSITE MATERIAL; CONTROLLED STUDY; FEMALE; GLUT4 GENE; HUMAN; HUMAN CELL; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PARTICLE SIZE; PILOT STUDY; PPARG GENE; PRIORITY JOURNAL; TISSUE ENGINEERING; TISSUE SCAFFOLD; UPREGULATION; VASCULARIZATION;

EID: 85027951939     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.1830     Document Type: Article

References (29)

1. Bauer-Kreisel P, Goepferich A, Blunk T. 2010; Cell-delivery therapeutics for adipose tissue regeneration. Adv Drug Deliv Rev 62: 798–813.
2. Beahm EK, Walton RL, Patrick CW Jr. 2003; Progress in adipose tissue construct development. Clin Plast Surg 30: 547–558.
3. Cho SW, Kim SS, Rhie JW, et al. 2005; Engineering of volume-stable adipose tissues. Biomaterials 26: 3577–3585.
4. Choi JH, Gimble JM, Lee K, et al. 2010; Adipose tissue engineering for soft tissue regeneration. Tissue Eng B Rev 16: 413–426.
5. Christiaens V, Lijnen HR. 2010; Angiogenesis and development of adipose tissue. Mol Cell Endocrinol 318: 2–9.
6. Cronin KJ, Messina A, Knight KR, et al. 2004; New murine model of spontaneous autologous tissue engineering, combining an arteriovenous pedicle with matrix materials. Plast Reconstr Surg 113: 260–269.
7. Dolderer JH, Abberton KM, Thompson EW, et al. 2007; Spontaneous large volume adipose tissue generation from a vascularized pedicled fat flap inside a chamber space. Tissue Eng 13: 673–681.
8. Eyrich D, Brandl F, Appel B, et al. 2007; Long-term stable fibrin gels for cartilage engineering. Biomaterials 28: 55–65.
9. Findlay MW, Messina A, Thompson EW, et al. 2009; Long-term persistence of tissue-engineered adipose flaps in a murine model to 1 year: an update, Plast Reconstr Surg 124: 1077–1084.
10. Flynn L, Woodhouse KA. 2008; Adipose tissue engineering with cells in engineered matrices. Organogenesis 4: 228–235.
11. Gimble JM, Katz AJ, Bunnell BA. 2007; Adipose-derived stem cells for regenerative medicine. Circ Res 100: 1249–1260.
12. Gomillion CT, Burg KJL. 2006; Stem cells and adipose tissue engineering. Biomaterials 27: 6052–6063.
13. von Heimburg D, Zachariah S, Low A, et al. 2001; Influence of different biodegradable carriers on the in vivo behaviour of human adipose precursor cells. Plast Reconstr Surg 108: 411–420.
14. Hwang CS, Loftus TM, Mandrup S, et al. 1997; Adipocyte differentiation and leptin expression. Annu Rev Cell Dev Biol 13: 231–259.
15. Kimura Y, Ozeki M, Inamoto T, et al. 2003; Adipose tissue engineering based on human preadipocytes combined with gelatin microspheres containing basic fibroblast growth factor. Biomaterials 24: 2513–2521.
16. Lee KY, Mooney DJ. 2001; Hydrogels for tissue engineering. Chem Rev 101: 1869–1879.
17. Nguyen A, Pasyk KA, Bouvier TN, et al. 1990; Comparative study of survival of autologous adipose tissue taken and transplanted by different techniques. Plast Reconstr Surg 85: 378–386.
18. Park HY, Kwon HM, Lim HJ, et al. 2001; Potential role of leptin in angiogenesis: leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro. Exp Mol Med 33: 95–102.
19. Patrick CW Jr. 2004; Breast tissue engineering. Annu Rev Biomed Eng 6: 109–130.
20. Patrick CW Jr. 2001; Tissue engineering strategies for adipose tissue repair. Anat Rec 263: 361–366.
21. Rosen ED, MacDougald OR. 2006; Adipocyte differentiation from the inside out. Mol Cell Biol 7: 885–896.
22. Tachi M, Yamada A. 2005; Choice of flaps for breast reconstruction. J Clin Oncol 10: 289–297.
23. Torio-Padron N, Baerlecken N, Momeni A, et al. 2007; Engineering of adipose tissue by injection of human preadipocytes in fibrin. Aesthetic Plast Surg 31: 285–293.
24. Tsuji W, Inamoto T, Yamashiro H, et al. 2009; Adipogenesis induced by human adipose tissue-derived stem cells. Tissue Eng A 15: 83–93.
25. Walton RL, Beahm EK, Wu L. 2004; De novo adipose tissue formation in a vascularized engineered construct. Microsurgery 24: 378–384.
26. Weiser B, Prantl L, Schubert TEO, et al. 2008; In vivo development and long-term survival of engineered adipose tissue depend on in vitro precultivation strategy. Tissue Eng A 14: 275–284.
27. Wiese H, Maier G. 2005; Open-pored polyurethane foam without skin formation, formulation for the production thereof and use thereof as a carrier material for cell and tissue cultures or medicaments. Patent No. WO/2006/032501 A1, Germany.
28. Wiggenhauser PS, Müller DF, Melchels FPW, et al. 2012; Engineering of vascularized adipose constructs. Cell Tissue Res 347: 747–757.
29. Yang S, Leong KF, Du Z, et al. 2001; The design of scaffolds for the use in tissue engineering. Part I. Traditional factors. Tissue Eng 7: 679–689.