Decatenation checkpoint-defective melanomas are dependent on PI3K for survival

Pigment cell & melanoma research

Volumn 27, Issue 5, 2014, Pages 813-821

  Brooks, Kelly ^a   Ranall, Max ^a   Spoerri, Loredana ^a   Stevenson, Alex ^a   Gunasingh, Gency ^a   Pavey, Sandra ^a   Meunier, Fred ^a   Gonda, Thomas J ^a   Gabrielli, Brian ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

decatenation checkpoint; melanoma; PI3K; synthetic lethality

Indexed keywords

1-(4-((4-(DIMETHYLAMINO)PIPERIDIN-1-YL)CARBONYL)PHENYL)-3-(4-(4,6-DIMORPHOLIN-4-YL-1,3,5-TRIAZIN-2-YL)PHENYL)UREA; CELL CYCLE PROTEIN; DNA TOPOISOMERASE (ATP HYDROLYSING); MORPHOLINE DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE; SMALL INTERFERING RNA; TRIAZINE DERIVATIVE;

ANTAGONISTS AND INHIBITORS; APOPTOSIS; CELL CYCLE CHECKPOINT; CELL SEPARATION; CHEMISTRY; DNA DAMAGE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MELANOMA; METABOLISM; POLYMERASE CHAIN REACTION; SKIN TUMOR; STEM CELL; TUMOR CELL LINE;

APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL SEPARATION; DNA DAMAGE; DNA TOPOISOMERASES, TYPE II; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MELANOMA; MORPHOLINES; PHOSPHATIDYLINOSITOL 3-KINASES; POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SKIN NEOPLASMS; STEM CELLS; TRIAZINES;

EID: 85027951882     PISSN: None     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/pcmr.12268     Document Type: Article

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