Joint bleeding in factor VIII deficient mice causes an acute loss of trabecular bone and calcification of joint soft tissues which is prevented with aggressive factor replacement

Haemophilia : the official journal of the World Federation of Hemophilia

Volumn 20, Issue 5, 2014, Pages 716-722

  Lau, A G ^a   Sun, J ^a   Hannah, W B ^a   Livingston, E W ^a   Heymann, D ^a   Bateman, T A ^a   Monahan, P E ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

bone density; factor VIII; haemarthrosis; joint degradation; microCT; mineralization

Indexed keywords

BLOOD CLOTTING FACTOR 8; COAGULATING AGENT;

ACUTE DISEASE; ANIMAL; CALCINOSIS; COMPLICATION; DISEASE MODEL; HEMARTHROSIS; HEMOPHILIA A; KNOCKOUT MOUSE; MALE; MICRO-COMPUTED TOMOGRAPHY; MOUSE; OSTEOARTHRITIS, KNEE; OSTEOPOROSIS; PATHOLOGY; TIBIA; TRABECULAR MESHWORK;

ACUTE DISEASE; ANIMALS; CALCINOSIS; COAGULANTS; DISEASE MODELS, ANIMAL; FACTOR VIII; HEMARTHROSIS; HEMOPHILIA A; MALE; MICE; MICE, KNOCKOUT; OSTEOARTHRITIS, KNEE; OSTEOPOROSIS; TIBIA; TRABECULAR MESHWORK; X-RAY MICROTOMOGRAPHY;

EID: 85027950984     PISSN: None     EISSN: 13652516     Source Type: Journal    
DOI: 10.1111/hae.12399     Document Type: Article

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