Artificial neural network associated to UV/Vis spectroscopy for monitoring bioreactions in biopharmaceutical processes

Bioprocess and Biosystems Engineering

Volumn 38, Issue 6, 2024, Pages

  Takahashi, Maria Beatriz ^a   Leme, Jaci ^b   Caricati, Celso Pereira ^b   Tonso, Aldo ^c   Fernández Núñez, Eutimio Gustavo ^a,c   Rocha, José Celso ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b INSTITUTO BUTANTAN   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Artificial neural network; Biopharmaceutical process; Bioreactor monitoring; UV Vis spectroscopy

Indexed keywords

AMINO ACIDS; ANIMAL CELL CULTURE; BIOREACTORS; CELLS; DISSOLVED OXYGEN; LEAST SQUARES APPROXIMATIONS; MAMMALS; METABOLITES; NEURAL NETWORKS; PROCESS CONTROL; PROCESS MONITORING;

BIOPHARMACEUTICAL PROCESS; BIOPHARMACEUTICALS; BIOREACTIONS; BIOREACTOR MONITORING; CELL CONCENTRATIONS; CULTURE MEDIUM; MAMMALIAN CELLS; SPECTROSCOPIC TECHNIQUE; UV/ VIS SPECTROSCOPY; VIABLE CELLS;

NUTRIENTS;

BIOLOGICAL PRODUCT; CULTURE MEDIUM;

ANIMAL; ARTIFICIAL NEURAL NETWORK; BIOREACTOR; CELL LINE; CULTURE MEDIUM; HAMSTER; PH; PROCEDURES; ULTRAVIOLET SPECTROPHOTOMETRY;

ANIMALS; BIOLOGICAL PRODUCTS; BIOREACTORS; CELL LINE; CRICETINAE; CULTURE MEDIA; HYDROGEN-ION CONCENTRATION; NEURAL NETWORKS (COMPUTER); SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 85027949164     PISSN: 16157591     EISSN: 16157605     Source Type: Journal    
DOI: 10.1007/s00449-014-1346-7     Document Type: Article

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