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Volumn 1, Issue 1, 2010, Pages 46-55

The potential role of indoleamine 2,3 dioxygenase (IDO) as a predictive and therapeutic target for diabetes treatment: A mythical truth

Author keywords

IDO; Individual tolerance; Predictive diagnostic; Targeted treatment; Type 1 diabetes

Indexed keywords

ABATACEPT; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 17; INTERLEUKIN 21; INTERLEUKIN 22;

EID: 85027947433     PISSN: 18785077     EISSN: 18785085     Source Type: Journal    
DOI: 10.1007/s13167-010-0009-2     Document Type: Review
Times cited : (10)

References (70)
  • 1
    • 33644511372 scopus 로고    scopus 로고
    • Crystal structure of human indoleamine 2, 3-dioxygenase: Catalytic mechanism of O2 incorporation by a heme-containing dioxygenase
    • Sugimoto H, Oda S, Otsuki T, et al. Crystal structure of human indoleamine 2, 3-dioxygenase: catalytic mechanism of O2 incorporation by a heme-containing dioxygenase. Proc Natl Acad Sci USA. 2006;103(8):2611-6.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.8 , pp. 2611-2616
    • Sugimoto, H.1    Oda, S.2    Otsuki, T.3
  • 2
    • 34249295962 scopus 로고    scopus 로고
    • Characterization of an indoleamine 2, 3-dioxygenase-like protein found in humans and mice
    • Ball HJ, Sanchez-Perez A, Weiser S, et al. Characterization of an indoleamine 2, 3-dioxygenase-like protein found in humans and mice. Gene 2007;396(1):203-13.
    • (2007) Gene , vol.396 , Issue.1 , pp. 203-213
    • Ball, H.J.1    Sanchez-Perez, A.2    Weiser, S.3
  • 3
    • 58149308592 scopus 로고    scopus 로고
    • Indoleamine 2, 3-dioxygenase-2; a new enzyme in the kynurenine pathway
    • Ball HJ, Yuasa HJ, Austin CJ, et al. Indoleamine 2, 3-dioxygenase-2; a new enzyme in the kynurenine pathway. Int J Biochem Cell Biol. 2009;41(3):467-71.
    • (2009) Int J Biochem Cell Biol , vol.41 , Issue.3 , pp. 467-471
    • Ball, H.J.1    Yuasa, H.J.2    Austin, C.J.3
  • 4
    • 34547643025 scopus 로고    scopus 로고
    • Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2, 3-dioxygenase inhibitory compound D-1-methyl-tryptophan
    • Metz R, Duhadaway JB, Kamasani U, et al. Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2, 3-dioxygenase inhibitory compound D-1-methyl-tryptophan. Cancer Res. 2007;67(15):7082-7.
    • (2007) Cancer Res , vol.67 , Issue.15 , pp. 7082-7087
    • Metz, R.1    Duhadaway, J.B.2    Kamasani, U.3
  • 5
    • 4043170040 scopus 로고    scopus 로고
    • Inhibition of experimental asthma by indoleamine 2, 3-dioxygenase
    • Hayashi T, Beck L, Rossetto C, et al. Inhibition of experimental asthma by indoleamine 2, 3-dioxygenase. J Clin Invest. 2004;114 (2):270-9.
    • (2004) J Clin Invest , vol.114 , Issue.2 , pp. 270-279
    • Hayashi, T.1    Beck, L.2    Rossetto, C.3
  • 6
    • 1842507884 scopus 로고    scopus 로고
    • Indoleamine 2, 3-dioxygenase expression is restricted to fetal trophoblast giant cells during murine gestation and is maternal genome specific
    • Baban B, Chandler P, McCool D, et al. Indoleamine 2, 3-dioxygenase expression is restricted to fetal trophoblast giant cells during murine gestation and is maternal genome specific. J Reprod Immunol. 2004;61(2):67-77.
    • (2004) J Reprod Immunol , vol.61 , Issue.2 , pp. 67-77
    • Baban, B.1    Chandler, P.2    McCool, D.3
  • 7
    • 33745819629 scopus 로고    scopus 로고
    • Expression of indoleamine 2, 3-dioxygenase (IDO) by endothelial cells: Implications for the control of alloresponses
    • Beutelspacher SC, Tan PH, McClure MO, et al. Expression of indoleamine 2, 3-dioxygenase (IDO) by endothelial cells: implications for the control of alloresponses. Am J Transplant. 2006;6 (6):1320-30.
    • (2006) Am J Transplant , vol.6 , Issue.6 , pp. 1320-1330
    • Beutelspacher, S.C.1    Tan, P.H.2    McClure, M.O.3
  • 8
    • 49949118291 scopus 로고    scopus 로고
    • Indoleamine 2, 3-dioxygenase expression promotes renal ischemia-reperfusion injury
    • Mohib K, Wang S, Guan Q, et al. Indoleamine 2, 3-dioxygenase expression promotes renal ischemia-reperfusion injury. Am J Physiol Renal Physiol. 2008;295(1):F226-34.
    • (2008) Am J Physiol Renal Physiol , vol.295 , Issue.1 , pp. 226-234
    • Mohib, K.1    Wang, S.2    Guan, Q.3
  • 9
    • 73249121300 scopus 로고    scopus 로고
    • Kynurenine Pathway Metabolites in Humans: Disease and Healthy States
    • Chen Y, Guillemin GJ. Kynurenine Pathway Metabolites in Humans: Disease and Healthy States. Int J Tryptophan Res. 2009;2:1-19.
    • (2009) Int J Tryptophan Res , vol.2 , pp. 1-19
    • Chen, Y.1    Guillemin, G.J.2
  • 10
    • 0043032808 scopus 로고    scopus 로고
    • Asp274 and his346 are essential for heme binding and catalytic function of human indoleamine 2, 3-dioxygenase
    • Littlejohn TK, Takikawa O, Truscott RJ, et al. Asp274 and his346 are essential for heme binding and catalytic function of human indoleamine 2, 3-dioxygenase. J Biol Chem. 2003;278(32):29525-31.
    • (2003) J Biol Chem , vol.278 , Issue.32 , pp. 29525-29531
    • Littlejohn, T.K.1    Takikawa, O.2    Truscott, R.J.3
  • 11
    • 77953421676 scopus 로고    scopus 로고
    • Targeting the immunoregulatory Indoleamine 2,3-dioxygenase pathway in Immunotherapy
    • Johnson BA, Baban B, Mellor AL (2009) Targeting the immunoregulatory Indoleamine 2,3-dioxygenase pathway in Immunotherapy. Immunotherapy 1(4)
    • (2009) Immunotherapy , vol.1 , Issue.4
    • Johnson, B.A.1    Baban, B.2    Mellor, A.L.3
  • 12
    • 0000056144 scopus 로고
    • Interferon gamma blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cells to degrade tryptophan
    • Pfefferkorn ER. Interferon gamma blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cells to degrade tryptophan. Proc Natl Acad Sci USA. 1984;81(3):908-12.
    • (1984) Proc Natl Acad Sci USA , vol.81 , Issue.3 , pp. 908-912
    • Pfefferkorn, E.R.1
  • 13
    • 0032555614 scopus 로고    scopus 로고
    • Prevention of allogeneic fetal rejection by tryptophan catabolism
    • Munn DH, Zhou M, Attwood JT, et al. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science 1998;281 (5380):1191-3.
    • (1998) Science , vol.281 , Issue.5380 , pp. 1191-1193
    • Munn, D.H.1    Zhou, M.2    Attwood, J.T.3
  • 14
    • 67649891954 scopus 로고    scopus 로고
    • The missing link between indoleamine 2, 3-dioxygenase mediated antibacterial and immunoregulatory effects
    • Müller A, Heseler K, Schmidt SK, et al. The missing link between indoleamine 2, 3-dioxygenase mediated antibacterial and immunoregulatory effects. J Cell Mol Med. 2009;13(6):1125-35.
    • (2009) J Cell Mol Med , vol.13 , Issue.6 , pp. 1125-1135
    • Müller, A.1    Heseler, K.2    Schmidt, S.K.3
  • 15
    • 70349419639 scopus 로고    scopus 로고
    • Indoleamine 2, 3-dioxygenase is involved in defense against Neospora caninum in human and bovine cells
    • Spekker K, Czesla M, Ince V, et al. Indoleamine 2, 3-dioxygenase is involved in defense against Neospora caninum in human and bovine cells. Infect Immun. 2009;77(10):4496-501.
    • (2009) Infect Immun , vol.77 , Issue.10 , pp. 4496-4501
    • Spekker, K.1    Czesla, M.2    Ince, V.3
  • 16
    • 63849112500 scopus 로고    scopus 로고
    • The role of indoleamine 2, 3-dioxygenase in the induction of immune tolerance: Focus on hematology
    • Curti A, Trabanelli S, Salvestrini V, et al. The role of indoleamine 2, 3-dioxygenase in the induction of immune tolerance: focus on hematology. Blood 2009;113(11):2394-401.
    • (2009) Blood , vol.113 , Issue.11 , pp. 2394-2401
    • Curti, A.1    Trabanelli, S.2    Salvestrini, V.3
  • 17
    • 0027462422 scopus 로고
    • Immunity to intracellular bacteria
    • Kaufmann SH. Immunity to intracellular bacteria. Annu Rev Immunol. 1993;11:129-63.
    • (1993) Annu Rev Immunol , vol.11 , pp. 129-163
    • Kaufmann, S.H.1
  • 18
    • 0018179447 scopus 로고
    • Induction of pulmonary indoleamine 2, 3- dioxygenase by intraperitoneal injection of bacterial lipopolysaccharide
    • Yoshida R, Hayaishi O. Induction of pulmonary indoleamine 2, 3- dioxygenase by intraperitoneal injection of bacterial lipopolysaccharide. Proc Natl Acad Sci USA. 1978;75:3998-4000.
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 3998-4000
    • Yoshida, R.1    Hayaishi, O.2
  • 19
    • 0034832976 scopus 로고    scopus 로고
    • Restriction of Toxoplasma gondii growth in human brain microvascular endothelial cells by activation of indoleamine 2, 3-dioxygenase
    • Däubener W, Spors B, Hucke C, et al. Restriction of Toxoplasma gondii growth in human brain microvascular endothelial cells by activation of indoleamine 2, 3-dioxygenase. Infect Immun.2001;69:6527-31.
    • (2001) Infect Immun , vol.69 , pp. 6527-6531
    • Däubener, W.1    Spors, B.2    Hucke, C.3
  • 20
    • 0037438465 scopus 로고    scopus 로고
    • Indoleamine 2, 3-dioxygenase is regulated by IFN-gamma in the mouse placenta during Listeria monocytogenes infection
    • Mackler AM, Barber EM, Takikawa O, et al. Indoleamine 2, 3-dioxygenase is regulated by IFN-gamma in the mouse placenta during Listeria monocytogenes infection. J Immunol. 2003;170: 823-30.
    • (2003) J Immunol , vol.170 , pp. 823-830
    • Mackler, A.M.1    Barber, E.M.2    Takikawa, O.3
  • 21
    • 0018649875 scopus 로고
    • Induction of indoleamine 2, 3-dioxygenase in mouse lung during virus infection
    • Yoshida R, Urade Y, Tokuda M, et al. Induction of indoleamine 2, 3-dioxygenase in mouse lung during virus infection. Proc Natl Acad Sci USA. 1979;76:4084-6.
    • (1979) Proc Natl Acad Sci USA , vol.76 , pp. 4084-4086
    • Yoshida, R.1    Urade, Y.2    Tokuda, M.3
  • 22
    • 67649295473 scopus 로고    scopus 로고
    • Balancing inflammation and tolerance in vivo through dendritic cells by the commensal Candida albicans
    • Epub 2009 May 6
    • Bonifazi P, Zelante T, D'Angelo C, De Luca A, Moretti S, Bozza S, et al. Balancing inflammation and tolerance in vivo through dendritic cells by the commensal Candida albicans. Mucosal Immunol. 2009;2(4):362-374. Epub 2009 May 6.
    • (2009) Mucosal Immunol , vol.2 , Issue.4 , pp. 362-374
    • Bonifazi, P.1    Zelante, T.2    D'Angelo, C.3    de Luca, A.4    Moretti, S.5    Bozza, S.6
  • 23
    • 58249103970 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase in infection: The paradox of an evasive strategy that benefits the host
    • Epub 2008 Oct 25
    • Zelante T, Fallarino F, Bistoni F, Puccetti P, Romani L. Indoleamine 2,3-dioxygenase in infection: the paradox of an evasive strategy that benefits the host. Microbes Infect. 2009;11(1):133-141. Epub 2008 Oct 25.
    • (2009) Microbes Infect , vol.11 , Issue.1 , pp. 133-141
    • Zelante, T.1    Fallarino, F.2    Bistoni, F.3    Puccetti, P.4    Romani, L.5
  • 24
    • 0142137237 scopus 로고    scopus 로고
    • Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2, 3-dioxygenase
    • Uyttenhove C, Pilotte L, Théate I, et al. Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2, 3-dioxygenase. Nat Med. 2003;9(10):1269-74.
    • (2003) Nat Med , vol.9 , Issue.10 , pp. 1269-1274
    • Uyttenhove, C.1    Pilotte, L.2    Théate, I.3
  • 25
    • 4043092238 scopus 로고    scopus 로고
    • Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes
    • Erratum in: J Clin Invest 114(4):599
    • Munn DH, Sharma MD, Hou D, et al. Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes. J Clin Invest. 2004;114(2):280-90. Erratum in: J Clin Invest 114(4):599.
    • (2004) J Clin Invest , vol.114 , Issue.2 , pp. 280-290
    • Munn, D.H.1    Sharma, M.D.2    Hou, D.3
  • 26
    • 16244408626 scopus 로고    scopus 로고
    • Inhibition of indoleamine 2, 3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy
    • Muller AJ, DuHadaway JB, Donover PS, et al. Inhibition of indoleamine 2, 3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy. Nat Med. 2005;11:312-9.
    • (2005) Nat Med , vol.11 , pp. 312-319
    • Muller, A.J.1    Duhadaway, J.B.2    Donover, P.S.3
  • 27
    • 70049096598 scopus 로고    scopus 로고
    • The paradoxical patterns of expression of indoleamine 2, 3-dioxygenase in colon cancer
    • Gao YF, Peng RQ, Li J, et al. The paradoxical patterns of expression of indoleamine 2, 3-dioxygenase in colon cancer. J Transl Med. 2009;7:71.
    • (2009) J Transl Med , vol.7 , pp. 71
    • Gao, Y.F.1    Peng, R.Q.2    Li, J.3
  • 28
    • 0142011214 scopus 로고    scopus 로고
    • Pattern of recruitment of immunoregulatory antigen-presenting cells in malignant melanoma
    • Lee JR, Dalton RR, Messina JL, et al. Pattern of recruitment of immunoregulatory antigen-presenting cells in malignant melanoma. Lab Invest. 2003;83(10):1457-66.
    • (2003) Lab Invest , vol.83 , Issue.10 , pp. 1457-1466
    • Lee, J.R.1    Dalton, R.R.2    Messina, J.L.3
  • 30
    • 33644775726 scopus 로고    scopus 로고
    • Prognostic value of indoleamine 2, 3-dioxygenase expression in colorectal cancer: Effect on tumor-infiltrating T cells
    • Brandacher G, Perathoner A, Ladurner R, et al. Prognostic value of indoleamine 2, 3-dioxygenase expression in colorectal cancer: effect on tumor-infiltrating T cells. Clin Cancer Res. 2006;12 (4):1144-51.
    • (2006) Clin Cancer Res , vol.12 , Issue.4 , pp. 1144-1151
    • Brandacher, G.1    Perathoner, A.2    Ladurner, R.3
  • 31
    • 23844451052 scopus 로고    scopus 로고
    • Indoleamine 2, 3-dioxygenase serves as a marker of poor prognosis in gene expression profiles of serous ovarian cancer cells
    • Okamoto A, Nikaido T, Ochiai K, et al. Indoleamine 2, 3-dioxygenase serves as a marker of poor prognosis in gene expression profiles of serous ovarian cancer cells. Clin Cancer Res. 2005;11(16):6030-9.
    • (2005) Clin Cancer Res , vol.11 , Issue.16 , pp. 6030-6039
    • Okamoto, A.1    Nikaido, T.2    Ochiai, K.3
  • 32
    • 34548024195 scopus 로고    scopus 로고
    • Increased synthesis of indoleamine-2, 3-dioxygenase protein is positively associated with impaired survival in patients with serous-type, but not with other types of, ovarian cancer
    • Takao M, Okamoto A, Nikaido T, et al. Increased synthesis of indoleamine-2, 3-dioxygenase protein is positively associated with impaired survival in patients with serous-type, but not with other types of, ovarian cancer. Oncol Rep. 2007;17(6):1333-9.
    • (2007) Oncol Rep , vol.17 , Issue.6 , pp. 1333-1339
    • Takao, M.1    Okamoto, A.2    Nikaido, T.3
  • 33
    • 53749088471 scopus 로고    scopus 로고
    • Expression and prognosis role of indoleamine 2, 3-dioxygenase in hepatocellular carcinoma
    • Pan K, Wang H, Chen MS, et al. Expression and prognosis role of indoleamine 2, 3-dioxygenase in hepatocellular carcinoma. J Cancer Res Clin Oncol. 2008;134(11):1247-53.
    • (2008) J Cancer Res Clin Oncol , vol.134 , Issue.11 , pp. 1247-1253
    • Pan, K.1    Wang, H.2    Chen, M.S.3
  • 34
    • 73949103808 scopus 로고    scopus 로고
    • Inducing the tryptophan catabolic pathway, indoleamine 2, 3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality
    • Jasperson LK, Bucher C, Panoskaltsis-Mortari A, et al. Inducing the tryptophan catabolic pathway, indoleamine 2, 3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality. Blood 2009;114(24):5062-70.
    • (2009) Blood , vol.114 , Issue.24 , pp. 5062-5070
    • Jasperson, L.K.1    Bucher, C.2    Panoskaltsis-Mortari, A.3
  • 36
    • 85028093624 scopus 로고    scopus 로고
    • Donor IL-4-treatment induces alternatively activated liver macrophages and IDO-expressing NK cells and promotes rat liver allograft acceptance
    • Wang C, Tay SS, Tran GT et al Donor IL-4-treatment induces alternatively activated liver macrophages and IDO-expressing NK cells and promotes rat liver allograft acceptance. Transpl Immunol [Epub ahead of print]
    • Transpl Immunol [Epub Ahead of Print]
    • Wang, C.1    Tay, S.S.2    Tran, G.T.3
  • 37
    • 27644587079 scopus 로고    scopus 로고
    • Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite
    • Erratum in: Science. 2006 Feb 17;311(5763):954
    • Platten M, Ho PP, Youssef S, et al. Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite. Science 2005;310(5749):850-855. Erratum in: Science. 2006 Feb 17;311(5763):954.
    • (2005) Science , vol.310 , Issue.5749 , pp. 850-855
    • Platten, M.1    Ho, P.P.2    Youssef, S.3
  • 38
    • 76249084930 scopus 로고    scopus 로고
    • Mesenchymal stem cells derived from human gingiva are capable of immunomodulatory functions and ameliorate inflammation-related tissue destruction in experimental colitis
    • Zhang Q, Shi S, Liu Y, et al. Mesenchymal stem cells derived from human gingiva are capable of immunomodulatory functions and ameliorate inflammation-related tissue destruction in experimental colitis. J Immunol. 2009;183(12):7787-98.
    • (2009) J Immunol , vol.183 , Issue.12 , pp. 7787-7798
    • Zhang, Q.1    Shi, S.2    Liu, Y.3
  • 39
    • 33751574468 scopus 로고    scopus 로고
    • Synovial autoreactive T cells in rheumatoid arthritis resist IDO-mediated inhibition
    • Zhu L, Ji F, Wang Y, et al. Synovial autoreactive T cells in rheumatoid arthritis resist IDO-mediated inhibition. J Immunol. 2006;177:8226-33.
    • (2006) J Immunol , vol.177 , pp. 8226-8233
    • Zhu, L.1    Ji, F.2    Wang, Y.3
  • 40
    • 54949123439 scopus 로고    scopus 로고
    • Distribution of myeloid dendritic cells and plasmacytoid dendritic cells in the synovial tissues of rheumatoid arthritis
    • Takakubo Y, Takagi M, Maeda K, et al. Distribution of myeloid dendritic cells and plasmacytoid dendritic cells in the synovial tissues of rheumatoid arthritis. J Rheumatol. 2008;35(10):1919-31.
    • (2008) J Rheumatol , vol.35 , Issue.10 , pp. 1919-1931
    • Takakubo, Y.1    Takagi, M.2    Maeda, K.3
  • 41
    • 67649216127 scopus 로고    scopus 로고
    • The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity
    • Scott GN, DuHadaway J, Pigott E, et al. The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity. J Immunol. 2009;182(12):7509-17.
    • (2009) J Immunol , vol.182 , Issue.12 , pp. 7509-7517
    • Scott, G.N.1    Duhadaway, J.2    Pigott, E.3
  • 42
    • 58249098408 scopus 로고    scopus 로고
    • Mouse pancreatic islets are resistant to indoleamine 2, 3 dioxygenaseinduced general control nonderepressible-2 kinase stress pathway and maintain normal viability and function
    • Jalili RB, Forouzandeh F, Moeenrezakhanlou A, et al. Mouse pancreatic islets are resistant to indoleamine 2, 3 dioxygenaseinduced general control nonderepressible-2 kinase stress pathway and maintain normal viability and function. Am J Pathol. 2009;174(1):196-205.
    • (2009) Am J Pathol , vol.174 , Issue.1 , pp. 196-205
    • Jalili, R.B.1    Forouzandeh, F.2    Moeenrezakhanlou, A.3
  • 43
    • 77649239326 scopus 로고    scopus 로고
    • IDO mediates TLR9-driven protection from experimental autoimmune diabetes
    • Fallarino F, Volpi C, Zelante T, et al. IDO mediates TLR9-driven protection from experimental autoimmune diabetes. J Immunol. 2009;183(10):6303-12.
    • (2009) J Immunol , vol.183 , Issue.10 , pp. 6303-6312
    • Fallarino, F.1    Volpi, C.2    Zelante, T.3
  • 44
    • 38449111402 scopus 로고    scopus 로고
    • The countervailing actions of myeloid and plasmacytoid dendritic cells control autoimmune diabetes in the nonobese diabetic mouse
    • Saxena V, Ondr JK, Magnusen AF, et al. The countervailing actions of myeloid and plasmacytoid dendritic cells control autoimmune diabetes in the nonobese diabetic mouse. J Immunol. 2007;179(8):5041-53.
    • (2007) J Immunol , vol.179 , Issue.8 , pp. 5041-5053
    • Saxena, V.1    Ondr, J.K.2    Magnusen, A.F.3
  • 45
    • 34249695524 scopus 로고    scopus 로고
    • Transient upregulation of indoleamine 2, 3-dioxygenase in dendritic cells by human chorionic gonadotropin downregulates autoimmune diabetes
    • Ueno A, Cho S, Cheng L, et al. Transient upregulation of indoleamine 2, 3-dioxygenase in dendritic cells by human chorionic gonadotropin downregulates autoimmune diabetes. Diabetes 2007;56(6):1686-93.
    • (2007) Diabetes , vol.56 , Issue.6 , pp. 1686-1693
    • Ueno, A.1    Cho, S.2    Cheng, L.3
  • 46
    • 33845694341 scopus 로고    scopus 로고
    • Non-invasive monitoring of kidney allograft rejection through IDO metabolism evaluation
    • Brandacher G, Cakar F, Winkler C, et al. Non-invasive monitoring of kidney allograft rejection through IDO metabolism evaluation. Kidney Int. 2007;71(1):60-7.
    • (2007) Kidney Int , vol.71 , Issue.1 , pp. 60-67
    • Brandacher, G.1    Cakar, F.2    Winkler, C.3
  • 47
    • 34247182736 scopus 로고    scopus 로고
    • Pharmacological targeting of IDO-mediated tolerance for treating autoimmune disease
    • Penberthy WT. Pharmacological targeting of IDO-mediated tolerance for treating autoimmune disease. Curr Drug Metab. 2007;8(3):245-66.
    • (2007) Curr Drug Metab , vol.8 , Issue.3 , pp. 245-266
    • Penberthy, W.T.1
  • 48
    • 1542374723 scopus 로고    scopus 로고
    • CDllc+ cells modulate pulmonary immune responses by production of indoleamine 2, 3-dioxygenase
    • Swanson KA, Zheng Y, Heidler KM, et al. CDllc+ cells modulate pulmonary immune responses by production of indoleamine 2, 3-dioxygenase. Am J Respir Cell Mol Biol. 2004; 30:311-8.
    • (2004) Am J Respir Cell Mol Biol , vol.30 , pp. 311-318
    • Swanson, K.A.1    Zheng, Y.2    Heidler, K.M.3
  • 49
    • 33645123655 scopus 로고    scopus 로고
    • Novel action of indoleamine 2, 3-dioxygenase attenuating acute lung allograft injury
    • Liu H, Liu L, Liu K, et al. Novel action of indoleamine 2, 3-dioxygenase attenuating acute lung allograft injury. Am J Respir Crit Care Med. 2006;173:566-72.
    • (2006) Am J Respir Crit Care Med , vol.173 , pp. 566-572
    • Liu, H.1    Liu, L.2    Liu, K.3
  • 50
    • 70249124641 scopus 로고    scopus 로고
    • Reduced cytotoxic function of effector CD8+ T cells is responsible for indoleamine 2, 3-dioxygenasedependent immune suppression
    • Liu H, Liu L, Liu K, et al. Reduced cytotoxic function of effector CD8+ T cells is responsible for indoleamine 2, 3-dioxygenasedependent immune suppression. J Immunol. 2009;183:1022-31.
    • (2009) J Immunol , vol.183 , pp. 1022-1031
    • Liu, H.1    Liu, L.2    Liu, K.3
  • 51
    • 70149101645 scopus 로고    scopus 로고
    • IDO activates regulatory T cells and blocks their conversion into Th17-like T cells
    • Baban B, Chandler PR, Sharma MD, et al. IDO activates regulatory T cells and blocks their conversion into Th17-like T cells. J Immunol. 2009;183(4):2475-83.
    • (2009) J Immunol , vol.183 , Issue.4 , pp. 2475-2483
    • Baban, B.1    Chandler, P.R.2    Sharma, M.D.3
  • 52
    • 68349116068 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells in autoimmune diabetes-potential tools for immunotherapy
    • Nikolic T, Welzen-Coppens JM, Leenen PJ, et al. Plasmacytoid dendritic cells in autoimmune diabetes-potential tools for immunotherapy. Immunobiology 2009;214(9-10):791-9.
    • (2009) Immunobiology , vol.214 , Issue.9-10 , pp. 791-799
    • Nikolic, T.1    Welzen-Coppens, J.M.2    Leenen, P.J.3
  • 53
    • 34848837386 scopus 로고    scopus 로고
    • Taking dendritic cells into medicine
    • Steinman RM, Banchereau J. Taking dendritic cells into medicine. Nature 2007;449(7161):419-26.
    • (2007) Nature , vol.449 , Issue.7161 , pp. 419-426
    • Steinman, R.M.1    Banchereau, J.2
  • 54
    • 63849217133 scopus 로고    scopus 로고
    • The divergence and interplay between pDC and mDC in humans
    • Kadowaki N. The divergence and interplay between pDC and mDC in humans. Front Biosci. 2009;14:808-17.
    • (2009) Front Biosci , vol.14 , pp. 808-817
    • Kadowaki, N.1
  • 55
    • 34548133569 scopus 로고    scopus 로고
    • Dendritic cells: A conductor of T cell differentiation
    • Kadowaki N. Dendritic cells: a conductor of T cell differentiation. Allergol Int. 2007;56(3):193-9.
    • (2007) Allergol Int , vol.56 , Issue.3 , pp. 193-199
    • Kadowaki, N.1
  • 56
    • 37549061827 scopus 로고    scopus 로고
    • Creating immune privilege: Active local suppression that benefits friends, but protects foes
    • Erratum in: Nat Rev Immunol. 2008 Feb;8(2):160
    • Mellor AL, Munn DH. Creating immune privilege: active local suppression that benefits friends, but protects foes. Nat Rev Immunol. 2008;8(1):74-80. Erratum in: Nat Rev Immunol. 2008 Feb;8(2):160
    • (2008) Nat Rev Immunol , vol.8 , Issue.1 , pp. 74-80
    • Mellor, A.L.1    Munn, D.H.2
  • 57
    • 22344438901 scopus 로고    scopus 로고
    • Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production
    • Nestle FO, Conrad C, Tun-Kyi A, et al. Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production. J Exp Med. 2005;202(1):135-43.
    • (2005) J Exp Med , vol.202 , Issue.1 , pp. 135-143
    • Nestle, F.O.1    Conrad, C.2    Tun-Kyi, A.3
  • 58
    • 44849114680 scopus 로고    scopus 로고
    • Immunomodulation of autoimmune diabetes by dendritic cells
    • Pechhold K, Koczwara K. Immunomodulation of autoimmune diabetes by dendritic cells. Curr Diab Rep. 2008;8(2):107-13.
    • (2008) Curr Diab Rep , vol.8 , Issue.2 , pp. 107-113
    • Pechhold, K.1    Koczwara, K.2
  • 59
    • 18544364477 scopus 로고    scopus 로고
    • Potential regulatory function of human dendritic cells expressing indoleamine 2, 3-dioxygenase
    • Munn DH, Sharma MD, Lee JR, et al. Potential regulatory function of human dendritic cells expressing indoleamine 2, 3-dioxygenase. Science 2002;297(5588):1867-70.
    • (2002) Science , vol.297 , Issue.5588 , pp. 1867-1870
    • Munn, D.H.1    Sharma, M.D.2    Lee, J.R.3
  • 60
    • 0036155562 scopus 로고    scopus 로고
    • Functional expression of indoleamine 2, 3-dioxygenase by murine CD8 alpha(+) dendritic cells
    • Fallarino F, Vacca C, Orabona C, et al. Functional expression of indoleamine 2, 3-dioxygenase by murine CD8 alpha(+) dendritic cells. Int Immunol. 2002;14(1):65-8.
    • (2002) Int Immunol , vol.14 , Issue.1 , pp. 65-68
    • Fallarino, F.1    Vacca, C.2    Orabona, C.3
  • 61
    • 26444489716 scopus 로고    scopus 로고
    • A minor population of splenic dendritic cells expressing CD19 mediates IDO-dependent T cell suppression via type I IFN signaling following B7 ligation
    • Baban B, Hansen AM, Chandler PR, et al. A minor population of splenic dendritic cells expressing CD19 mediates IDO-dependent T cell suppression via type I IFN signaling following B7 ligation. Int Immunol. 2005;17(7):909-19.
    • (2005) Int Immunol , vol.17 , Issue.7 , pp. 909-919
    • Baban, B.1    Hansen, A.M.2    Chandler, P.R.3
  • 62
    • 50549088692 scopus 로고    scopus 로고
    • Functional dichotomy of plasmacytoid dendritic cells: Antigen-specific activation of T cells versus production of type I interferon
    • Jaehn PS, Zaenker KS, Schmitz J, et al. Functional dichotomy of plasmacytoid dendritic cells: antigen-specific activation of T cells versus production of type I interferon. Eur J Immunol. 2008;38 (7):1822-32.
    • (2008) Eur J Immunol , vol.38 , Issue.7 , pp. 1822-1832
    • Jaehn, P.S.1    Zaenker, K.S.2    Schmitz, J.3
  • 63
    • 34848837386 scopus 로고    scopus 로고
    • Taking dendritic cells into medicine
    • Steinman RM, Banchereau J. Taking dendritic cells into medicine. Nature 2007;449(7161):419-26.
    • (2007) Nature , vol.449 , Issue.7161 , pp. 419-426
    • Steinman, R.M.1    Banchereau, J.2
  • 64
    • 1042291134 scopus 로고    scopus 로고
    • Tryptophan catabolism in nonobese diabetic mice
    • Grohmann U, Fallarino F, Bianchi R, et al. Tryptophan catabolism in nonobese diabetic mice. Adv Exp Med Biol. 2003; 527:47-54.
    • (2003) Adv Exp Med Biol , vol.527 , pp. 47-54
    • Grohmann, U.1    Fallarino, F.2    Bianchi, R.3
  • 65
    • 70449707629 scopus 로고    scopus 로고
    • Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone
    • Fallarino F, Luca G, Calvitti M, et al. Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone. J Exp Med. 2009;206(11):2511-26.
    • (2009) J Exp Med , vol.206 , Issue.11 , pp. 2511-2526
    • Fallarino, F.1    Luca, G.2    Calvitti, M.3
  • 66
    • 50449087345 scopus 로고    scopus 로고
    • Interferon-alpha initiates type 1 diabetes in nonobese diabetic mice
    • Li Q, Xu B, Michie SA, et al. Interferon-alpha initiates type 1 diabetes in nonobese diabetic mice. Proc Natl Acad Sci USA. 2008;105(34):12439-44.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.34 , pp. 12439-12444
    • Li, Q.1    Xu, B.2    Michie, S.A.3
  • 67
    • 10744226191 scopus 로고    scopus 로고
    • Frequencies of dendritic cells (myeloid DC and plasmacytoid DC) and their ratio reduced in pregnant women: Comparison with umbilical cord blood and normal healthy adults
    • Ueda Y, Hagihara M, Okamoto A, et al. Frequencies of dendritic cells (myeloid DC and plasmacytoid DC) and their ratio reduced in pregnant women: comparison with umbilical cord blood and normal healthy adults. Hum Immunol. 2003;64(12):1144-51.
    • (2003) Hum Immunol , vol.64 , Issue.12 , pp. 1144-1151
    • Ueda, Y.1    Hagihara, M.2    Okamoto, A.3
  • 68
    • 34848915783 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2, 3-dioxygenase
    • Sharma MD, Baban B, Chandler P, et al. Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2, 3-dioxygenase. J Clin Invest. 2007;117(9):2570-82.
    • (2007) J Clin Invest , vol.117 , Issue.9 , pp. 2570-2582
    • Sharma, M.D.1    Baban, B.2    Chandler, P.3
  • 69
    • 15244349785 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells in immunity
    • Colonna M, Trinchieri G, Liu YJ. Plasmacytoid dendritic cells in immunity. Nat Immunol. 2004;5(12):1219-26.
    • (2004) Nat Immunol , vol.5 , Issue.12 , pp. 1219-1226
    • Colonna, M.1    Trinchieri, G.2    Liu, Y.J.3
  • 70
    • 33748861223 scopus 로고    scopus 로고
    • From plasmacytoid to dendritic cell: Morphological and functional switches during plasmacytoid pre-dendritic cell differentiation
    • Soumelis V, Liu YJ. From plasmacytoid to dendritic cell: morphological and functional switches during plasmacytoid pre-dendritic cell differentiation. Eur J Immunol. 2006;36(9):2286-92.
    • (2006) Eur J Immunol , vol.36 , Issue.9 , pp. 2286-2292
    • Soumelis, V.1    Liu, Y.J.2


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