Liquid chromatography tandem mass spectrometry quantitation of intracellular concentrations of ganciclovir and its phosphorylated forms

Analytical and Bioanalytical Chemistry

Volumn 407, Issue 12, 2021, Pages

  Billat, Pierre André ^a   Sauvage, François Ludovic ^a,b   Picard, Nicolas ^a,b   Tafzi, Naїma ^b   Alain, Sophie ^b   Essig, Marie ^a,b   Marquet, Pierre ^a,b   Saint Marcoux, Franck ^a,b,c  

^a Univ Limoges   (France)

^b LIMOGES UNIVERSITY HOSPITAL   (France)

^c UNIVERSITY OF LIMOGES   (France)

Author keywords

Ganciclovir; Intracellular; LC MS MS; Metabolites

Indexed keywords

ANTIVIRAL AGENTS; BIOMARKERS; BLOOD; CELLS; CHLORINE COMPOUNDS; CYTOLOGY; DRUG PRODUCTS; MASS SPECTROMETERS; MASS SPECTROMETRY; METABOLITES; PHASE SEPARATION; PHOSPHATASES; PHOSPHORYLATION; POTASSIUM COMPOUNDS; TOXICITY;

GANCICLOVIR; INTRACELLULAR; INTRACELLULAR CONCENTRATION; LC-MS/MS; LIQUID CHROMATOGRAPHY COUPLED TO TANDEM MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; SOLID-PHASE EXTRACTION; US FOOD AND DRUG ADMINISTRATION;

LIQUID CHROMATOGRAPHY;

ACID PHOSPHATASE; GANCICLOVIR; POTASSIUM CHLORIDE;

BLOOD; CALIBRATION; CHEMISTRY; DEVICES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; KIDNEY TRANSPLANTATION; METABOLISM; PHOSPHORYLATION; PROCEDURES; REPRODUCIBILITY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

ACID PHOSPHATASE; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GANCICLOVIR; HUMANS; KIDNEY TRANSPLANTATION; PHOSPHORYLATION; POTASSIUM CHLORIDE; REPRODUCIBILITY OF RESULTS; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

EID: 85027944563     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-015-8554-0     Document Type: Article

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