Characterization of the co-elution of host cell proteins with monoclonal antibodies during protein A purification

Biotechnology progress

Volumn 32, Issue 3, 2016, Pages 708-717

  Zhang, Qingchun ^a   Goetze, Andrew M ^a   Cui, Huanchun ^a   Wylie, Jenna ^a   Tillotson, Ben ^a   Hewig, Art ^a   Hall, Michael P ^a   Flynn, Gregory C ^a  

^a AMGEN INC   (United States)

Author keywords

host cell proteins; mass spectrometry; monoclonal antibody; protein A

Indexed keywords

CELL CULTURE; CELLS; MAMMALS; MASS SPECTROMETRY; MONOCLONAL ANTIBODIES; PRASEODYMIUM COMPOUNDS; PURIFICATION; REMOVAL; TISSUE CULTURE;

AMERICAN INSTITUTE OF CHEMICAL ENGINEERS; COMPREHENSIVE COMPARISONS; HOST CELL PROTEIN; LIMITED INFORMATION; MONOCLONAL ANTIBODIES (MAB); PROTEIN A; PROTEIN A CHROMATOGRAPHY; RETENTION MECHANISM;

CHROMATOGRAPHY;

MONOCLONAL ANTIBODY; STAPHYLOCOCCUS PROTEIN A;

ANIMAL; CELL CULTURE; CHEMISTRY; CHO CELL LINE; CRICETULUS; ISOLATION AND PURIFICATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

ANIMALS; ANTIBODIES, MONOCLONAL; CELLS, CULTURED; CHO CELLS; CHROMATOGRAPHY, LIQUID; CRICETULUS; MASS SPECTROMETRY; STAPHYLOCOCCAL PROTEIN A;

EID: 85027939781     PISSN: None     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.2272     Document Type: Article

References (33)