In vitro Phase I and Phase II metabolism of α-pyrrolidinovalerophenone (α-PVP), methylenedioxypyrovalerone (MDPV) and methedrone by human liver microsomes and human liver cytosol

Analytical and Bioanalytical Chemistry

Volumn 407, Issue 19, 2021, Pages

  Negreira, Noelia ^a   Erratico, Claudio ^a   Kosjek, Tina ^b   van Nuijs, Alexander L N ^a   Heath, Ester ^b   Neels, Hugo ^a   Covaci, Adrian ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b JO EF STEFAN INSTITUTE   (Slovenia)

Author keywords

Cathinones; In vitro metabolism; MDPV; Methedrone; New psychoactive substances; Quadrupole time of flight mass spectrometry; PVP

Indexed keywords

BIOMOLECULES; HYDROXYLATION; KETONES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; NEGATIVE IONS;

CATHINONES; IN-VITRO; MDPV; METHEDRONE; NEW PSYCHOACTIVE SUBSTANCES; QUADRUPOLE TIME OF FLIGHT MASS SPECTROMETRY;

METABOLITES;

1,3 BENZODIOXOLE DERIVATIVE; 3,4-METHYLENEDIOXYPYROVALERONE; 4-METHOXYMETHCATHINONE; ALPHA-PYRROLIDINOVALEROPHENONE; CYTOCHROME; PROPIOPHENONE DERIVATIVE; PYRROLIDINE DERIVATIVE;

CYTOSOL; ENZYMOLOGY; HUMAN; LIVER; LIVER MICROSOME; METABOLISM; TANDEM MASS SPECTROMETRY;

BENZODIOXOLES; CYTOCHROMES; CYTOSOL; HUMANS; LIVER; MICROSOMES, LIVER; PROPIOPHENONES; PYRROLIDINES; TANDEM MASS SPECTROMETRY;

EID: 85027939008     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-015-8763-6     Document Type: Article

References (0)