Sustained analgesia achieved through esterase-activated morphine prodrugs complexed with PAMAM dendrimer.

Pharmaceutical research

Volumn 30, Issue 1, 2013, Pages 247-256

  Ward, Brent B ^a   Huang, Baohua ^b   Desai, Ankur ^b   Cheng, Xue Min ^b   Vartanian, Mark ^b   Zong, Hong ^b   Shi, Xiangyang ^b   Thomas, Thommey P ^b   Kotlyar, Alina E ^b   Van Der Spek, Abraham ^b   Leroueil, Pascale R ^b   Baker, James R ^b  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DENDRIMER; MORPHINE; NARCOTIC ANALGESIC AGENT; PAMAM STARBURST; PRODRUG;

ANIMAL; ARTICLE; CHEMISTRY; DELAYED RELEASE FORMULATION; GUINEA PIG; MALE; PAIN; RAT; SOLUBILITY; SPRAGUE DAWLEY RAT;

ANALGESICS, OPIOID; ANIMALS; DELAYED-ACTION PREPARATIONS; DENDRIMERS; GUINEA PIGS; MALE; MORPHINE; PAIN; PRODRUGS; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY;

MLCS; MLOWN;

EID: 85027937034     PISSN: None     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-012-0869-3     Document Type: Article

References (0)