Influence of process conditions on the crystallization and transition of metastable mannitol forms in protein formulations during lyophilization.

Pharmaceutical research

Volumn 30, Issue 1, 2013, Pages 131-139

  Cao, Wenjin ^a   Xie, Yong ^b   Krishnan, Sampathkumar ^b   Lin, Hong ^b   Ricci, Margaret ^b  

^a AMGEN INC   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

MANNITOL; PROTEIN; SUCROSE;

ARTICLE; CHEMISTRY; CRYSTALLIZATION; FREEZE DRYING; METHODOLOGY; POWDER DIFFRACTION; RAMAN SPECTROMETRY; X RAY DIFFRACTION;

CRYSTALLIZATION; FREEZE DRYING; MANNITOL; POWDER DIFFRACTION; PROTEINS; SPECTRUM ANALYSIS, RAMAN; SUCROSE; X-RAY DIFFRACTION;

EID: 85027935299     PISSN: None     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-012-0855-9     Document Type: Article

References (0)