Pyrimidino piperazinyl acetamides: Innovative class of hybrid acetamide drugs as potent antimicrobial and antimycobacterial agents

Pharmaceutical Chemistry Journal

Volumn 46, Issue 1, 2012, Pages 26-34

  Kanagarajan, V ^a,b   Gopalakrishnan, M ^b  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^b ANNAMALAI UNIVERSITY   (India)

Author keywords

2 (4 Methylpiperazin 1 yl) N (4,6 diarylpyrimidin 2 yl)acetamides; Antibacterial activity; Antifungal activity; Antitubercular activity; N methylpiperazine

Indexed keywords

2 (4 METHYLPIPERAZIN 1 YL) N (4,6 DIPHENYLPYRIMIDIN 2 YL)ACETAMIDE; 2 (4 METHYLPIPERAZIN 1 YL) N [4 (4 METHYLPHENYL) 6 PHENYLPYRIMIDIN 2 YL]ACETAMIDE; ACETAMIDE DERIVATIVE; ANTIINFECTIVE AGENT; ANTIMYCOBACTERIAL AGENT; CIPROFLOXACIN; ETHAMBUTOL; FLUCONAZOLE; ISONIAZID; N [4 (4 FLUOROPHENYL) 6 (4 METHOXYPHENYL)PYRIMIDIN 2 YL] 2 (4 METHYLPIPERAZIN 1 YL)ACETAMIDE; N [4 (4 FLUOROPHENYL) 6 PHENYLPYRIMIDIN 2 YL] 2 (4 METHYLPIPERAZIN 1 YL)ACETAMIDE; N [4 (4 METHYLPHENYL) 6 (4 FLUOROPHENYL)PYRIMIDIN 2 YL] 2 (4 METHYLPIPERAZIN 1 YL)ACETAMIDE; N [4 (4 METHYLPHENYL) 6 (4 METHOXYPHENYL)PYRIMIDIN 2 YL] 2 (4 METHYLPIPERAZIN 1 YL)ACETAMIDE; N [4 PHENYL 6 (4 METHOXYPHENYL)PYRIMIDIN 2 YL) 2 (4 METHYLPIPERAZIN 1 YL)ACETAMIDE; N [4,6 BIS (4 FLUOROPHENYL)PYRIMIDIN 2 YL] 2 (4 METHYLPIPERAZIN 1 YL)ACETAMIDE; PYRAZINAMIDE; RIFAMPICIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTHRODERMA GYPSEUM; ARTICLE; ASPERGILLUS FLAVUS; CONTROLLED STUDY; DRUG SYNTHESIS; ESCHERICHIA COLI; GROWTH INHIBITION; IN VITRO STUDY; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; MUCOR INDICUS; MUCORALES; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PSEUDOMONAS AERUGINOSA; RHIZOPUS ARRHIZUS; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS; VIBRIO CHOLERAE;

EID: 85027929803     PISSN: 0091150X     EISSN: 15739031     Source Type: Journal    
DOI: 10.1007/s11094-012-0729-9     Document Type: Article

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