Moderate alcohol intake lowers biochemical markers of bone turnover in postmenopausal women

Menopause

Volumn 19, Issue 9, 2012, Pages 974-979

  Marrone, Jill A ^a   Maddalozzo, Gianni F ^a   Branscum, Adam J ^a   Hardin, Karin ^a   Cialdella Kam, Lynn ^a   Philbrick, Kenneth A ^a   Breggia, Anne C ^b   Rosen, Clifford J ^b   Turner, Russell T ^a   Iwaniec, Urszula T ^a  

^a OREGON STATE UNIVERSITY   (United States)

^b Maine Medical Center Research Institute   (United States)

Author keywords

C terminal telopeptide; Dual energy X ray absorptiometry; Ethanol; Osteocalcin; Osteoporosis; Serum estradiol

Indexed keywords

ALCOHOL; BIOLOGICAL MARKER; CARBOXY TERMINAL TELOPEPTIDE; OSTEOCALCIN;

ADULT; ALCOHOL ABSTINENCE; ALCOHOL CONSUMPTION; ALCOHOL WITHDRAWAL; ARTICLE; BONE DENSITY; BONE TURNOVER; CONTROLLED STUDY; CORRELATIONAL STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; HUMAN; IMMUNOASSAY; OSSIFICATION; OSTEOLYSIS; POSTMENOPAUSE;

EID: 85027926415     PISSN: 10723714     EISSN: 15300374     Source Type: Journal    
DOI: 10.1097/gme.0b013e31824ac071     Document Type: Article

References (35)

1. Melton LJ III, Thamer M, Ray NF, et al. Fractures attributable to osteoporosis: report from the National Osteoporosis Foundation. J Bone Miner Res 1997;12:16-23.
2. Garnero P, Delmas PD. Contribution of bone mineral density and bone turnover markers to the estimation of risk of osteoporotic fracture in postmenopausal women. J Musculoskelet Neuronal Interact 2004;4:50-63.
3. Kamel HR. Postmenopausal osteoporosis: etiology, current diagnosis, strategies, and nonprescription interventions. J Manag Care Pharm 2006;12: S4-S9.
4. Leeming DJ, Alexandersen P, Karsdal MA, Qvist P, Schaller S, Tanko LB. An update on biomarkers of bone turnover and their utility in biomedical research and clinical practice. Eur J Clin Pharmacol 2006;62:781-792.
5. US Department of Health and Human Services. Bone Health and Osteoporosis: A Report of the Surgeon General. Rockville, MD: US Department of Health and Human Services, Office of the Surgeon General, 2004.
6. Reid IR. Anti-resorptive therapies for osteoporosis. Semin Cell Dev Biol 2008;19:473-478.
7. Lane N. Osteoporosis: is there a rational approach to fracture prevention. Bull NYU Hosp Jt Dis 2006;64:67-71.
8. Chappard D, Plantard B, Petitjean M, Alexandre C, Riffat G. Alcoholic cirrhosis and osteoporosis in men: a light and scanning electron microscopy study. J Stud Alcohol 1991;52:269-274.
9. de Vernejoul MC, Bielakoff J, Herve M, et al. Evidence for defective osteoblastic function. A role for alcohol and tobacco consumption in osteoporosis in middle-aged men. Clin Orthop Relat Res 1983:107-115.
10. Chavassieux P, Serre CM, Vergnaud P, Delmas PD, Meunier PJ. In vitro evaluation of dose-effects of ethanol on human osteoblastic cells. Bone Miner 1993;22:95-103.
11. Friday KE, Howard GA. Ethanol inhibits human bone cell proliferation and function in vitro. Metabolism 1991;40:562-565.
12. Klein RF, Fausti KA, Carlos AS. Ethanol inhibits human osteoblastic cell proliferation. Alcohol Clin Exp Res 1996;20:572-578.
13. Berg KM, Kunins HV, Jackson JL, et al. Association between alcohol consumption and both osteoporotic fracture and bone density. Am J Med 2008;121:406-418.
14. Feskanich D, Korrick SA, Greenspan SL, Rosen HN, Colditz GA. Moderate alcohol consumption and bone density among postmenopausal women. J Womens Health 1999;8:65-73.
15. Ganry O, Baudoin C, Fardellone P. Effect of alcohol intake on bone mineral density in elderly women: The EPIDOS Study. Epidemiologie de l'Osteoporose. Am J Epidemiol 2000;151:773-780.
16. Holbrook TL, Barrett-Connor E. A prospective study of alcohol consumption and bone mineral density. BMJ 1993;306:1506-1509.
17. Ilich JZ, Brownbill RA, Tamborini L, Crncevic-Orlic Z. To drink or not to drink: how are alcohol, caffeine and past smoking related to bone mineral density in elderly women? J Am Coll Nutr 2002;21:536-544.
18. Rapuri PB, Gallagher JC, Balhorn KE, Ryschon KL. Alcohol intake and bone metabolism in elderly women. Am J Clin Nutr 2000;72:1206-1213.
19. Wosje KS, Kalkwarf HJ. Bone density in relation to alcohol intake among men and women in the United States. Osteoporos Int 2007;18: 391-400.
20. Turner RT, Kidder LS, Kennedy A, Evans GL, Sibonga JD. Moderate alcohol consumption suppresses bone turnover in adult female rats. J Bone Miner Res 2001;16:589-594.
21. Kanis JA, Melton LJ III, Christiansen C, Johnston CC, Khaltaev N. The diagnosis of osteoporosis. J Bone Miner Res 1994;9:1137-1141.
22. Turner RT, Wronski TJ, Zhang M, Kidder LS, Bloomfield SA, Sibonga JD. Effects of ethanol on gene expression in rat bone: transient dosedependent changes in mRNA levels for matrix proteins, skeletal growth factors, and cytokines are followed by reductions in bone formation. Alcohol Clin Exp Res 1998;22:1591-1599.
23. Hassager C, Risteli J, Risteli L, Jensen SB, Christiansen C. Diurnal variation in serum markers of type I collagen synthesis and degradation in healthy premenopausal women. J Bone Miner Res 1992;7:1307-1311.
24. Qvist P, Christgau S, Pedersen BJ, Schlemmer A, Christiansen C. Circadian variation in the serum concentration of C-terminal telopeptide of type I collagen (serum CTx): effects of gender, age, menopausal status, posture, daylight, serum cortisol, and fasting. Bone 2002;31:57-61.
25. Szulc P, Delmas PD. Biochemical markers of bone turnover: potential use in the investigation and management of postmenopausal osteoporosis. Osteoporos Int 2008;19:1683-1704.
26. Wichers M, Schmidt E, Bidlingmaier F, Klingmuller D. Diurnal rhythm of CrossLaps in human serum. Clin Chem 1999;45:1858-1860.
27. International Center for Alcohol Policies Blue Book, module 20. Available at: http://www.icap.org/PolicyTools/ICAPBlueBook/BlueBookModules/ 20StandardDrinks/tabid/161/Default.aspx. Accessed June 1, 2011.
28. Turner C. How much alcohol is in a Fstandard drink? An analysis of 125 studies. Br J Addict 1990;85:1171-1175.
29. Di Castelnuovo A, Costanzo S, Bagnardi V, Donati MB, Iacoviello L, de Gaetano G. Alcohol dosing and total mortality in men and women: an updated meta-analysis of 34 prospective studies. Arch Intern Med 2006;166:2437-2445.
30. Felson DT, Zhang Y, Hannan MT, Kannel WB, Kiel DP. Alcohol intake and bone mineral density in elderly men and women. The Framingham Study. Am J Epidemiol 1995;142:485-492.
31. Agerbaek MO, Eriksen EF, Kragstrup J, Mosekilde L, Melsen F. A reconstruction of the remodelling cycle in normal human cortical iliac bone. Bone Miner 1991;12:101-112.
32. Sripanyakorn S, Jugdaohsingh R, Mander A, Davidson SL, Thompson RP, Powell JJ. Moderate ingestion of alcohol is associated with acute ethanol-induced suppression of circulating CTx in a PTH-independent fashion. J Bone Miner Res 2009;24:1380-1388.
33. Chen WY, Rosner B, Hankinson SE, Colditz GA, Willett WC. Moderate alcohol consumption during adult life, drinking patterns, and breast cancer risk. JAMA 2011;306:1884-1890.
34. Ronksley PE, Brien SE, Turner BJ, Mukamal KJ, Ghali WA. Association of alcohol consumption with selected cardiovascular disease outcomes: a systematic review and meta-analysis. BMJ 2011;342:d671.
35. Purohit V. Can alcohol promote aromatization of androgens to estrogens? A review. Alcohol 2000;22:123-127.