Diethyldithiocarbamate induces apoptosis in neuroblastoma cells by raising the intracellular copper level, triggering cytochrome c release and caspase activation.

Toxicology in vitro : an international journal published in association with BIBRA

Volumn 27, Issue 1, 2013, Pages 349-357

  Matias, Andreza C ^a   Manieri, Tânia M ^b   Cipriano, Samantha S ^b   Carioni, Vivian M O ^b   Nomura, Cassiana S ^b   Machado, Camila M L ^b   Cerchiaro, Giselle ^b  

^a UNIVERSIDADE FEDERAL DO ABC   (Brazil)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; COPPER; CYTOCHROME C; DIETHYLDITHIOCARBAMIC ACID; PROTEIN BCL 2; PROTEIN P53;

APOPTOSIS; ARTICLE; CELL SURVIVAL; DRUG EFFECT; ENZYME ACTIVATION; HUMAN; METABOLISM; NEUROBLASTOMA; TUMOR CELL LINE;

APOPTOSIS; CASPASES; CELL LINE, TUMOR; CELL SURVIVAL; COPPER; CYTOCHROMES C; DITIOCARB; ENZYME ACTIVATION; HUMANS; NEUROBLASTOMA; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR SUPPRESSOR PROTEIN P53;

MLCS; MLOWN;

EID: 85027924086     PISSN: None     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2012.08.017     Document Type: Article

References (0)